Clinical research is a necessity if effective and safe treatments are to be developed. However, this may well include the need for research that is best described as ‘invasive’ in that it may be associated with some discomfort or inconvenience. Limitations in the undertaking of invasive research involving people with intellectual disabilities (ID) are perhaps related to anxieties within the academic community and among ethics committees; however, the consequence of this neglect is that innovative treatments specific to people with ID (...) may not be developed. Such concerns are likely to continue while there is limited published knowledge regarding the actual experiences of people with ID who have participated in invasive clinical research. As part of a pilot study trialling the novel use of a surgically inserted device to curb overeating in people with Prader–Willi syndrome (PWS) we have investigated the experience of research through semistructured qualitative interviews involving three participants and their carers. Thematic analysis revealed that the adults with PWS and their family carers rated their participation positively, seeing it as a rewarding and enriching experience. This brief report discusses findings from our interview data in order to highlight strategies which may ensure that research is acceptable to participants, meets the necessary ethical standards and is able to achieve the aims set out by the researchers. To our knowledge, this is the first study to record experiences directly from people with PWS and their carers regarding their involvement in invasive clinical research. (shrink)

I argue for a deflationary answer to the question, “What is it to be a woman?” Prior attempts by feminist theorists to provide a metaphysical account of what all and only women have in common have all failed for the same reason: there is nothing women have in common beyond being women. Although the social kinds man and woman are primitive, their existence can be explained. I say that human sex difference is the material ground of systems of gender; gender (...) systems serve to enable male control of female reproductive capacities. This explains the fact that most women are female, but it does not entail that all women are female or that all females are women. To clarify my position, I draw an analogy between the kind woman and the kind parent. While it is difficult to come up with necessary and sufficient conditions for being a parent, it is clear that the social institution or practice of parenting has its material ground in the biological facts about human reproduction together with facts about infantile dependency. Saying this does not entail that all and only biological progenitors are parents. (shrink)

The term "Philosophic lyric".--Introductory chapter.--The "return to nature"; Wordsworth's "philosophy of nature".--The period between Wordsworth and Meredith.--Wordsworth and Meredith as poets of nature.--Browning and Meredith as poets of man.--Conclusion.

Renowned as the chief challenger of traditional views of morality, man's freedom, and religion from 1650-1750, Benedict de Spinoza (1632-77) spread alarm and ...

side or other from his conception of reality ; for though some kind of reality is generally allowed to exist on the other side, ... Thus to the ordinary man philosophy seems to offer no choice, but either to destroy absolutely one half of his sense of ...

Paper 3 This paper discusses how patriarchy made the name 'man' their Brand. It would guarantee their entitlement to rule and control the masses by repeating man in so many names. Partial lists are shown.

The final published book by Nobel Prize-winning author and philosopher Henri Bergson (1859-1941), La pensée et le mouvant (translated here as The Creative Mind), is a masterly autobiography of his philosophical method. Through essays and lectures written between 1903 and 1923, Bergson retraces how and why he became a philosopher, and crafts a fascinating critique of philosophy itself. Until it leaves its false paths, he demonstrates, philosophy will remain only a wordy dialectic that surmounts false problems. With masterful skill and (...) intensity, Bergson shows that metaphysics and science must be rooted in experience for philosophy to become a genuine search for truth. And in the quest for unanswered questions, the spiritual dimension of human life and the importance of intuition must be emphasized. A source of inspiration for physicists as well as philosophers, Bergson's introduction to metaphysics reveals a philosophy that is always on the move, blending man's spiritual drive with his mastery of the material world. (shrink)

The main claim in this article is that the traditionally Western and currently dominant understandings of the figures of “Nature” and “Animal” underlie and structure different forms of oppression and should be critically confronted. The racial-sexual subjugation of the colonized African draws symbolically on the older Western symbolic subjugations of Animal and Woman. In the Great Chain of Being of Western metaphysics it is Woman’s sexual body that links humans to the domain of the animal, and Man’s intellect that distinguishes (...) and separates humans from that same domain. Situated in the border between human and Animal, Woman merges with the chaos and fleshiness of Animal and Nature. With the emergence of race as a category of classification and colonial justification, the African is placed at the furthest remove from Western Man, the epitome of reasonable humanity. African Woman, in particular, is seen as the Animal Other. The colonial-“civilizing” project thus institutes a certain flight from Nat... (shrink)

In this article the authors discuss in broad strokes the work of two theorists, namely Nigerian sociologist Oyèrónkẹ́ Oyěwùmí and Argentinian philosopher Maria Lugones to argue that a specific logic of sexualisation accompanied, permeated and coloured the colonial project of racialising the ‘native’. The sexual wound which to a great extent explains the abjection of the racialised body, is a key aspect of the colony and should therefore also be a central theme in any properly critical discourse on decolonisation in (...) Africa. After drawing on Oyĕwùmí and Lugones to make their central argument, the authors apply this framework to the problem of sexual violence in South Africa. Understanding the nature of the sexual-racial wound of coloniality will not only ensure that the problem of sexual violence gets properly addressed as a central question of decolonisation, but will also suggest new ways of concretely addressing the problem. In particular, the dominant discourse needs to shift away from the ‘emasculated man’ trope and towards a critical feminist decoloniality which views the radical dehumanisation of native woman as key to colonial violence understood as a world-destructive. (shrink)

The purpose of the following text is to give readers a general introduction to Gordon Pask’s conversation theory, which is considered here to be a cybernetic and epistemological account of concept-forming and concept-sharing through conversational discourse and practice. While Pask devoted three lengthy tomes to articulate the theory and its applications, I believe it is necessary to give readers who are interested in conversation theory a general introduction to what I believe are the key features of his work in this (...) area. I argue that conversation theory should be considered an inferential account of the theory of concepts rather than a representational account, by virtue of Pask’s argument that a concept must be a process that involves many other concepts. (shrink)

Howard Adelmann’s majestic five volume Marcello Malpighi and the Evolution of Embryology was published nearly 50 years ago. A mix of paraphrase and translation, as well as extended commentary, Adelmann described Malpighi as “one of the cardinal figures in the history of biology. As we look back over the three centuries that separate him from us, he may, for all his towering stature, at first glance seem a distant figure. And yet he and his work are not so remote after (...) all” . Much has changed in the history of biology since Adelmann’s groundbreaking work, and among the many lessons to be taken from Domenico Bertoloni-Meli’s carefully researched, persuasive and, at times, beautifully rendered book is that the life sciences in the early modern period must be studied with an eye to the history of science, medicine and philosophy—i.e., calling Malpighi simply a “biologist” is very liable to mislead. This point, though only implicit in Meli’s choice to study Malpighi “in relati .. (shrink)

Descartes is well known as a mathematician and natural philosopher. However, none of Descartes's biographers has described the invitation he received in 1633 to fill a chair in theoretical medicine at the University of Bologna, or the fact that he was already sufficiently known and respected for his medical knowledge that the invitation came four years before his first publication. In this note I authenticate and contextualize this event, which I refer to as the ‘Bologna affair’. I transcribe the letter (...) written to the Bolognese Senate announcing efforts to bring Descartes to the university and explain the events that led to Descartes receiving the invitation. While many questions about the Bologna affair cannot be answered because of the paucity of the historical record, I conclude that the event invites us to consider again the larger historiographical issue of how best to integrate the history of medicine with the history of science and philosophy during the early modern period. (shrink)

We describe a machine learning system for the recognition of names in biomedical texts. The system makes extensive use of local and syntactic features within the text, as well as external resources including the web and gazetteers. It achieves an F- score of 70% on the Coling 2004 NLPBA/BioNLP shared task of identifying five biomedical named entities in the GENIA corpus.

In _Always More Than One_, the philosopher, visual artist, and dancer Erin Manning explores the concept of the "more than human" in the context of movement, perception, and experience. Working from Whitehead's process philosophy and Simondon's theory of individuation, she extends the concepts of movement and relation developed in her earlier work toward the notion of "choreographic thinking." Here, she uses choreographic thinking to explore a mode of perception prior to the settling of experience into established categories. Manning (...) connects this to the concept of "autistic perception," described by autistics as the awareness of a relational field prior to the so-called neurotypical tendency to "chunk" experience into predetermined subjects and objects. Autistics explain that, rather than immediately distinguishing objects—such as chairs and tables and humans—from one another on entering a given environment, they experience the environment as gradually taking form. Manning maintains that this mode of awareness underlies all perception. What we perceive is never first a subject or an object, but an ecology. From this vantage point, she proposes that we consider an ecological politics where movement and relation take precedence over predefined categories, such as the neurotypical and the neurodiverse, or the human and the nonhuman. What would it mean to embrace an ecological politics of collective individuation? (shrink)

The author reflects on the relation between the different veins of Bentham's thought and on the various experiences which influenced them.

The relationship between psychology and Christian theology has been one of the most important topics in the science and religion field. Discussions, however, are too frequently one-sided. This book takes an alternative approach, following the lead of Fraser Watts, the contributions develop various aspects of the mutual enrichment of each discipline by the other. Beyond outdated models of conflict and independence, this book highlights areas of fruitful enhancement at the interface of Christian belief and practice with psychology. Set out in (...) four sections the book's chapters first engage methodological and substantive issues in the interdisciplinarity raised by the dialogue between psychology and theology. Secondly, chapters explore a variety of areas in which psychology enriches theology, looking at both historical and contemporary themes such as psychoanalysis, embodiment and mindfulness. Chapters in the third section explore some of the theological enrichments of psychology, with topics including character strengths, wisdom, and forgiveness. The final section engages aspects of the mutual enrichment in religious life and pastoral care with an applied focus on mental health, meditation, prayer, spiritual direction and spirituality. A refreshing alternative study of the mutual enrichment of psychology and theology with theoretical and practical applications, this book reinforces the need for both disciplines to pursue creative and constructive engagement with each other. Of interest to scholars in psychology, theology, religious studies this book will also be of interest more widely as a case study of successful interdisciplinary work. (shrink)

Paul Tillich is one of the most important theologians of the twentieth century, and he produced a corpus of work that is considered canon for Western theology. While his influence is broad in and beyond the field of religious studies, his historic or ideological connection to radical theology has been hotly debated for decades. This introduction engages Tillich’s work as a whole but focuses upon what elements of Tillich are specifically employed by radical theologians, but more importantly, makes the case (...) that Tillich is, in fact, not only influential upon radical theology but rather that he should be counted among them as a proto-radical Christian thinker. (shrink)

There are now over 1.1 million people overseen by Immigration and Customs Enforcement (ICE), with about 33,000 detained in jails and federal detention centers around the country at any particular time. The average detention time is two months, but some are detained for much longer periods. Since its inception, one hundred and twenty one deaths and countless cases of medical neglect have occurred. Given its secrecy, and lack of accountability and oversight, it is not clear how many of these deaths (...) are the result of grossly inadequate medical care. ICE is a branch of a government agency in a democratic country, thus the citizens on whose behalf it allegedly operates have an obligation to ensure that it operates in conformity with the fundamental principles of justice on which this nation was founded. ICE is a young and rapidly growing bureaucracy with little oversight. It operates using a mix of federal, state, local and private centers, many of which are penal institutions. It has a history of serious abuse, and even when it operates in conformity with its penal standards, it inflicts additional harm onto vulnerable people, especially asylum seekers and parents of minor children. It thus requires our constant vigilance and concern. Our immigration policies and detention practices are deeply troubling, but until we elect to reform them, we have a special obligation to the vulnerable populations that we house in ICE detention. (shrink)

An update of one of the indispensable political and social histories of African Americans since World War II.

This study contributes to the growing interest in how hybrid organizations manage paradoxical social–business tensions. Our empirical case is “impact sourcing”—hybrids in global supply chains that hire staff from disadvantaged communities to provide services to business clients. We identify two major growth orientations—“community-focused” and “client-focused” growth—their inherent tensions and ways that hybrids manage them. The former favors slow growth and manages tensions through highly integrated client and community relations; the latter promotes faster growth and manages client and community relations separately. (...) Both growth orientations address social–business tensions in particular ways, but also create latent constraints that manifest when entrepreneurial aspirations conflict with the current growth path. In presenting and discussing our findings, we introduce preempting management practices of tensions, and the importance of geographic embeddedness and distance to the paradox literature. (shrink)

Current methods of obtaining consent for emergency neonatal research are flawed. They risk aggravating the distress of parents of preterm and other sick neonates. This distress, and the inevitable time constraints, compromise understanding and voluntariness, essential components of adequately informed consent. Current practice may be unjust in over-representing babies of more vulnerable and deprived parents. The research findings may thus not be generalisable. Informing parents antenatally about the possible need for emergency neonatal research, with presumed consent and scope for opting (...) out, would address these problems. It would spare parents of sick neonates, already terrified by their baby's illness, further distress. Experience with opting out suggests that recruitment might increase, thus generating earlier results, without compromising parental understanding of the nature and purpose of the research. (shrink)

In July 1787, Dr John Elliot, apothecary and scientist, assaulted Miss Mary Boydell in the streets of London. Elliotś defenders sought his acquittal on the grounds of insanity, and cited as proof a paper in which he alleged the existence of intelligent life on the surface of the sun. He has since become a stock character in the history of astronomy, routinely cited as a pathetic example of the ignorance of his age. His reputation is undeserved since his claims were (...) well within the canon of the era, and since his anti-social behaviour may well be explained by considering the hazards of his profession. Rather than serving as an exemplar of science gone awry, Elliot's dilemma can provide an opportunity for fresh analysis of late eighteenth-century thought on solar structure and on the processes that sustain it. (shrink)

I defend and clarify my arguments in "Real Representation of Fictional Objects" in response to criticisms from Joseph Sartorelli. In particular, I clarify why Kripke's notion of "levels of language" and a pragmatic principle suggested by van Inwagen do not support the view that works of fiction generate fictional objects but do not represent them.

The place of God in Nietzsche’s thought remains central and controversial. Nietzsche’s proclamation of 'the death of God' is one of the most famous slogans in modern philosophy, seeming to encapsulate the nineteenth-century loss of religious faith in the affirmation that God has "turned out to be our oldest lie" and yet the nature of Nietzsche’s own ‘theology’ is far from clear. This volume engages with Nietzsche’s arguments about God, theology, and religion. The volume extends the discussion to an engagement (...) of Nietzsche with alternative models of God, with ancient Greek religions, and with discussions of diversity in dis/conjunction with religion. The chapters examine Nietzsche’s genealogy of religion and his claims about the place of God and theology in the history of Western thought, as well as his engagements with alternative conceptions of God. The volume also examines the historical and contemporary reception of Nietzsche’s arguments about God by religious and non-religious thinkers, asking to what extent Nietzsche’s philosophy of God speaks to the challenges of today's globalized philosophy and religion. (shrink)

This three-part paper presents Gordon Pask’s conversation theory (CT) and interaction of actors theory (IA) and outlines ways to apply these cybernetic approaches to designing technologies and scenarios for both formal and informal learning. The first part of the paper covers concepts central to CT and IA, explaining the relationship between conceptual and mechanical operators, and machines mediating informal and formal learning. The second part of the paper applies visual representations of CT and IA to understanding the use of Pask’s (...) course assembly systems (CASTE and THOUGHTSTICKER), created between the late 1960s and the 1980s, and the ThoughtShuffler search interface, created in the 2010s. The third part proposes two pathways for design based on CT and IA: firstly, the potential for designers and observers to reformulate the qualities of tools and learning scenarios to augment human thinking and collective action; and secondly, the possibility to create tools with malleable interfaces that allow users to become intermediaries rather than consumers of knowledge. (shrink)