A collection of one man's essays in book form tends to be viewed today with some suspicion, if not hostility, by philosophical critics. It would seem that the author is guilty of an academic sin of pride: causing or helping to cause separately conceived articles to surpass their original station and assume a new life, a grander articulation. It can hardly be denied that the essays which follow must face this sullen charge, for they were composed at different times (...) for different sorts of audiences and, for the most part, have already been published. Their appearance in a new form will not allay commonplace criticisms: there are repetitions, certain key terms are defined and defined again in various places, a few quotations reappear, and, beyond this, the essays are unequal in range, depth, and fundamental intent. But it is what brings these essays together that constitutes, I trust, their collective merit. Underlying the special arguments that are to be found in each of the chapters is a particular sense of reality, not a thesis or a theory but rather a way of seeing the world and of appreciating its texture and design. It is that sense of reality that I should like to speak of here. Philosophy stands in a paradoxical relationship to mundane ex istence: it is at once its critique and one of its possibilities. (shrink)

Due to the variation, contingency and complexity of living systems, biology is often taken to be a science without fundamental theories, laws or general principles. I revisit this question in light of the quest for design principles in systems biology and show that different views can be reconciled if we distinguish between different types of generality. The philosophical literature has primarily focused on generality of specific models or explanations, or on the heuristic role of abstraction. This paper takes a (...) different approach in emphasizing a theory-constituting role of general principles. Design principles signify general dependencyrelations between structures and functions, given a set of formally defined constraints. I contend that design principles increase our understanding of living systems by relating specific models to general types. The categorization of types is based on a delineation of the scope of biological possibilities, which serves to identify and define the generic features of classes of systems. To characterize the basis for general principles through generic abstraction and reasoning about possibility spaces, I coin the term constraint-based generality. I show that constraintbased generality is distinct from other types of generality in biology, and argue that general principles play a unifying role that does not entail theory reduction. (shrink)

Christian Emden’s book is a contribution to the current debates in the English-language literature over Nietzsche’s “naturalism.” Emden regards this subject as “crucial to any understanding of Friedrich Nietzsche’s philosophical thought”, claiming that the “central task of Nietzsche’s philosophical project” is to “translate humanity back into nature,” as Nietzsche himself puts it in BGE 230. However, Emden does not undertake to demonstrate this thesis as such. Rather, he aims to interpret Nietzsche’s naturalism in terms of the “problem of normativity”, (...) that of how the sources of normativity can be understood without appealing to a normative standard independent of us as natural beings.... (shrink)

What's Next? Michael Crichtons und Mikhail Bulgakovs Kritik der Fetischisierung in den Lebenswissenschaften. Dieser Beitrag wurde angeregt durch den Thriller Next (2006) von Michael Crichton. Im Gegensatz zu dessen State of Fear (2004), wo die Behandlung eines aktuellen wissenschaftspolitischen Problems – des Klimawandels – mit einer harschen Kritik am Umgang politischer Aktivisten mit wissenschaftlichen Ergebnissen einhergeht, setzt Next Hoffnungen und Ängste ins Zentrum, die im Zusammenhang mit dem ‚Human Genome Project‘ verhandelt wurden. Crichton stellt hier wissenschaftlich‐ökonomische Verflechtungen dar, vor denen (...) er schon in seinen Romanen zu Jurassic Park (1990) warnte. Hier wird auf die Gefahr der Fetischisierung im Zusammenhang mit utopisch untermalten wissenschaftlich‐technischen Großprojekten und der Phantasie ‚Leben zu machen‘ hingewiesen, und es werden entsprechende Motive und Narrative der,longue‐durée‘ aufgegriffen, z.B. künstliche Menschen, menschliche Hybris und das Außer‐Kontrolle‐Geraten wissenschaftlich‐technischer Großprojekte. Unter der Fragestellung, wie kritische Wissenschaftsreflexion im Medium von Literatur erfolgen kann und was der spezifische Beitrag aus der Wissenschaftsgeschichte wäre, behandelt dieser Essay neben Werken von Michael Crichton (vor allem Next und Lost World, 1997) auch die satirischen Novellen Die verhängnisvollen Eier (1924/1925) und Hundeherz (1926/1968) von Mikhail Bulgakov, da bereits dort die (mögliche) künstliche Hervorbringung von Lebewesen unter der Bedingung eines (versuchten) direkten Zugriffs auf deren Reproduktionsmechanismen fokussiert wurde. Wissenschaftskritik als Gesellschaftskritik zeigt sich hier als Reflexion auf die Grenzen zwischen Wissenschaft und Gesellschaft und auf die Verantwortung der entlang dieser Grenzen agierenden Menschen, aber auch auf strukturelle Gewalt und deren Auswirkungen auf die Verhältnisse zwischen Menschen und Naturdingen sowie unter Menschen.Summary: What's Next? Michael Crichton's and Mikhail Bulgakov's Criticism of Fetishism in the Life Sciences. This paper was first inspired by Michael Crichton's last thriller, Next (2006), which staged hopes and fears triggered by the completion of the Human Genome Project and by the perfection of Polymerase chain reaction techniques, enabling the replication of DNA on a large scale. These developments nourished fantasies about the artificial (re)construction of living beings from DNA. Crichton had already warned of the fetishization of artificially produced living beings in Jurassic Park and in the novels on which the film was based inventing a futuristic scenario where this was happening on a large scale. Here, the topics of hubris and hybrids were center stage. In Next, the fetishization of life is an effect of the growing encroachment of economic actors upon the life sciences. This paper compares Crichton's criticism of techno‐scientific fetishism with Mikhail Bulgakov's critical account of human tinkering with the reproductive organs of humans and non‐humans in his two satirical novels The Fateful Eggs and Dog's Heart. The works of both authors link criticism of science with criticism of society. They focus the borders between science and society and analyze the responsibilities of humans who are acting along those borders. The thrillers and satirical novels illustrate the – often violent – power relations between humans and nature and also among humans. Comparing two authors who wrote nearly a century apart from each other and focussing different social systems will help compare longue‐durée and more specific forms of techno‐scientific fetishism. (shrink)

This paper finds its origin in a debate between Georges Bataille (1897-1962) and Octavio Paz (1914-1998) on what is central to the idea of eroticism. Bataille posits that violence and transgression are fundamental to eroticism, and without prohibition, eroticism would cease to exist. Paz, however, views violence and transgression as merely intersecting with, rather than being intrinsic to, eroticism. Paz places focus on imagination, and transforms eroticism from a transgressive, to a ritualistic act. Eroticism thus functions as an intermediary, turning (...) animal sexuality into ceremony and rite. In this paper, I argue that Paz and Bataille are not fundamentally at odds in their conceptualisation of eroticism. Instead, Paz redefines the locus of eroticism by subverting its unsettling aspects. His conception of eroticism gives precedence to the imagination, which in itself is an act of violation. Imagination transgresses normal life, but this transgression – the violation of the habitual world – also introduces a glimpse of the numinous that Paz associates with belongingness. The paper further explores eroticism, as this is perceived today, and argues that it ultimately eliminates the threshold marked by transgression. The rise of the contemporary pornographic society is marked by a loss of imagination and transcendence, which ultimately reduces the subject into a mere automaton that demands instant gratification. (shrink)

This collection addresses two different audiences: 1) historians and philosophers of the life sciences reflecting on collaborations across disciplines, especially as regards defining and addressing Grand Challenges; 2) researchers and other stakeholders involved in cross-disciplinary collaborations aimed at tackling Grand Challenges in the life and medical sciences. The essays collected here offer ideas and resources both for the study and for the practice of goal-driven cross-disciplinary research in the life and medical sciences. We organise (...) this introduction in three sections. The first section provides some background and context. The second motivates our take on this topic and then outlines the central ideas of each paper. The third section highlights the specificity and significance of this approach by considering: a) how this collection departs from existing literature on inter- and trans-disciplinarity, b) what is characteristic about this approach, and c) what role this suggests for the history and philosophy of the life sciences in addressing Grand Challenges. (shrink)

Vitalism is understood as impacting the history of the life sciences, medicine and philosophy, representing an epistemological challenge to the dominance of mechanism over the last 200 years, and partly revived with organicism in early theoretical biology. The contributions in this volume portray the history of vitalism from the end of the Enlightenment to the modern day, suggesting some reassessment of what it means both historically and conceptually. As such it includes a wide range of material, employing both (...) historical and philosophical methodologies, and it is divided fairly evenly between 19th and 20th century historical treatments and more contemporary analysis. This volume presents a significant contribution to the current literature in the history and philosophy of science and the history of medicine. (shrink)

ABSTRACTThe early history of anthropology in eighteenth-century Germany wove together contributions from medicine, metaphysics, and a host of other disciplines in an attempt to develop a holistic ‘science of man.’ This paper examines a literary text written by prominent figure in that movement, Johann Gottlob Krüger’s Dreams. The collection of parables staged as dreams in this book presents specifically literary cases against the sufficiency of either philosophy or physiology for the study of human life as a whole. Through close (...) readings of a number of these dreams and related texts, this paper shows how Krüger’s Dreams advocates an approach to anthropology that recognizes the importance of literature for an interdisciplinary study of human life. More than simply recognising literary writing as another means of studying human life, the vision of a new anthropology implied in this book draws on literary devices to counter the overconfidence and partisanship of existing philosophical and medical theories of human nature. (shrink)

"All art should become science and all science art; poetry and philosophy should be made one." Friedrich Schlegel's words perfectly capture the project of the German Romantics, who believed that the aesthetic approaches of art and literature could reveal patterns and meaning in nature that couldn't be uncovered through rationalistic philosophy and science alone. In this wide-ranging work, Robert J. Richards shows how the Romantic conception of the world influenced (and was influenced by) both the lives of the people (...) who held it and the development of nineteenth-century science. Integrating Romantic literature, science, and philosophy with an intimate knowledge of the individuals involved—from Goethe and the brothers Schlegel to Humboldt and Friedrich and Caroline Schelling—Richards demonstrates how their tempestuous lives shaped their ideas as profoundly as their intellectual and cultural heritage. He focuses especially on how Romantic concepts of the self, as well as aesthetic and moral considerations—all tempered by personal relationships—altered scientific representations of nature. Although historians have long considered Romanticism at best a minor tributary to scientific thought, Richards moves it to the center of the main currents of nineteenth-century biology, culminating in the conception of nature that underlies Darwin's evolutionary theory. Uniting the personal and poetic aspects of philosophy and science in a way that the German Romantics themselves would have honored, The Romantic Conception of Life alters how we look at Romanticism and nineteenth-century biology. (shrink)

The problem of function statements in the Life Sciences may be stated as follows. Life Scientists make frequent and important use of statements of the form 'X is the function of Y', in explaining phenomena intimately connected with living organisms. The use of such statements, according to recent philosophical discussions suffers the defects of presupposing or committing the user to the existence of vital forces, purposive activity outside the realm of human action, or a special kind of (...) ';causal' nexus, i.e. final causality, or constitutes the basis for the irreducibility of the LIFE sciences to physics . ;Because scientists find such statements so useful they are not willing to throw these statements out altogether. Instead the philosopher embarks on a program to 'save' such statements by showing that upon analysis function statements do not really suffer the above-mentioned defects. This analysis of function statements into statements of efficient causality shows them to be causal in a way which does not commit one to vital forces, purposive activity outside the realm of human activity, or final causality, and does not provide ammunition for those who would resist the reduction of Biology to Physics. ;First I consider attempts which have been made in the philosophical literature to analyze function statements into regular causal statements. I provide in the course of these considerations a positive account of the legitimate use of function statements in the life sciences which is non-reductive yet does not involve any of the defects which motivate the standard philosophical analyses. This positive account sees function statements as compacted explanations which among other distinguishing uses and characteristics focus on a special class of consequences. (shrink)

There is a crisis of valuation practices in the current academic life sciences, triggered by unsustainable growth and “hyper-competition.” Quantitative metrics in evaluating researchers are seen as replacing deeper considerations of the quality and novelty of work, as well as substantive care for the societal implications of research. Junior researchers are frequently mentioned as those most strongly affected by these dynamics. However, their own perceptions of these issues are much less frequently considered. This paper aims at contributing to (...) a better understanding of the interplay between how research is valued and how young researchers learn to live, work and produce knowledge within academia. We thus analyze how PhD students and postdocs in the Austrian life sciences ascribe worth to people, objects and practices as they talk about their own present and future lives in research. We draw on literature from the field of valuation studies and its interest in how actors refer to different forms of valuation to account for their actions. We explore how young researchers are socialized into different valuation practices in different stages of their growing into science. Introducing the concept of “regimes of valuation” we show that PhD students relate to a wider evaluative repertoire while postdocs base their decisions on one dominant regime of valuing research. In conclusion, we discuss the implications of these findings for the epistemic and social development of the life sciences, and for other scientific fields. (shrink)

Francis Bacon, the English philosopher, statesman and jurist, is best known for developing the empiricist method which forms the basis of modern science. Bacon's writings concentrated on philosophy and judicial reform. His most significant work is the Instauratio Magna comprising two parts - The Advancement of Learning and the Novum Organum. The first part is noteworthy as the first major philosophical work published in English. James Spedding and his co-editors arranged this fourteen-volume edition, published in London between 1857 and 1874, (...) not in chronological order but by subject matter, so that different volumes would appeal to different audiences. The material is divided into three parts: philosophy and general literature; legal works; and letters, speeches and tracts relating to politics. Volume 11, published in 1868, contains Bacon's political writings and letters from 1608 to 1613, including his treatise on the Irish plantations presented to King James I. (shrink)

Francis Bacon, the English philosopher, statesman and jurist, is best known for developing the empiricist method which forms the basis of modern science. Bacon's writings concentrated on philosophy and judicial reform. His most significant work is the Instauratio Magna comprising two parts - The Advancement of Learning and the Novum Organum. The first part is noteworthy as the first major philosophical work published in English. James Spedding and his co-editors arranged this fourteen-volume edition, published in London between 1857 and 1874, (...) not in chronological order but by subject matter, so that different volumes would appeal to different audiences. The material is divided into three parts: philosophy and general literature; legal works; and letters, speeches and tracts relating to politics. Published in 1869, Volume 12 contains Bacon's letters and writings between 1613 and 1616, which primarily relate to his appointment as Attorney General. (shrink)

Francis Bacon, the English philosopher, statesman and jurist, is best known for developing the empiricist method which forms the basis of modern science. Bacon's writings concentrated on philosophy and judicial reform. His most significant work is the Instauratio Magna comprising two parts - The Advancement of Learning and the Novum Organum. The first part is noteworthy as the first major philosophical work published in English. James Spedding and his co-editors arranged this fourteen-volume edition, published in London between 1857 and 1874, (...) not in chronological order but by subject matter, so that different volumes would appeal to different audiences. The material is divided into three parts: philosophy and general literature; legal works; and letters, speeches and tracts relating to politics. Volume 13, published in 1872, contains Bacon's papers from 1616 to 1618 and relate to his appointment as Lord Chancellor, and England's relations with Ireland and Spain. (shrink)

A review of Arthur Goldhammer's 1988 translation of Georges Canguilhem's Idéologie et rationalité dans l’histoire des sciences de la vie.

Previous chapter In her book Die Form des Werdens: Eine Kulturgeschichte der Embryologie, 1760-1830, Janina Wellmann claims that around 1800 the concept of rhythm has emerged and penetrated the entire Western culture. In literature, in theoretical reflection on art, in philosophy, but especially in the newest life sciences, rhythm would have become a common scientific “Paradigm” or better yet, a new “Episteme”. It would be great if it is true. But I think - Sur le concept de (...) rythme – Nouvel article. (shrink)

Staying for an answer : the untidy process of groping for truth -- The same, only different -- The unity of truth and the plurality of truths -- Coherence, consistency, cogency, congruity, cohesiveness, &c. : remain calm! don't go overboard! -- Not cynicism, but synechism : lessons from classical pragmatism -- Science, economics, "vision" -- The integrity of science : what it means, why it matters -- Scientific secrecy and "spin" : the sad, sleazy story of the trials of remune (...) -- Truth and justice, inquiry and advocacy, science and law -- Trial and error : the Supreme Court's philosophy of science -- An epistemologist among the epidemiologists -- Fallibilism and faith, naturalism and the supernatural, science and religion -- The ideal of intellectual integrity, in life and literature -- After my own heart : Dorothy Sayers's feminism -- Worthwhile lives -- Why I am not an oxymoron -- Formal philosophy? : a plea for pluralism. (shrink)

Against the background of the current discussion about self-organization theories and complexity theories and their application within biology and ecology, the question of teleology gains a new significance. Some scholars insist on the total elimination of any reference to teleology from the realm of the natural sciences. However, it seems especially hard to eradicate teleological expressions from scientific language when the issue of understanding living beings is at stake. For this reason, other scholars opt for a middle path that (...) allows for some teleological language. Yet, it is an open question whether teleological expressions are to be considered as playing a merely metaphorical or a necessary heuristic role in the sciences. Moreover, the ontological presuppositions, which underpin different positions in the debate, need to be depicted and analyzed. This paper aims at addressing the question of teleology within the life sciences by taking into account both Kant’s critical philosophy and Whitehead’s ontology. My analysis starts with Georg Toepfer’s distinction among different concepts of teleology and then focuses on the role of “internal purposiveness” (innere Zweckmäßigkeit) for biology today. I show how purposiveness (Zweckmäßigkeit; hereafter: ZM) corresponds to a very complex form of reciprocal causation (Wechselwirkung) rather than to any model of final causation. Drawing on Kant’s analysis of “natural purposes” in the Critique of Judgment as well as selforganization theory, I claim that reciprocal causation – however complex it might well be – is not sufficient to describe living beings adequately. However, since the natural sciences are still caught up in the presuppositions of modern scientistic and materialistic ontology, a step beyond mere efficient causation seems to be impossible within their methodological framework. And yet, as I will show, a genuine teleology of nature implies the idea of anticipation of totality. This kind of teleological consideration is presented at first in its role as a regulative concept in Kantian terms. Finally, I follow the path of Whitehead’s ‘philosophy of organism’ and claim for natural teleology the state of a necessary ontological presupposition. Whitehead’s ontology offers an ontological underpinning for teleological issues that, by avoiding any recourse to supernatural forces, invites life and natural sciences to a fruitful dialogue at the limit of their methodological boundaries, pressing them beyond their unreflected presuppositions. (shrink)

The Empire of Chance tells how quantitative ideas of chance transformed the natural and social sciences, as well as daily life over the last three centuries. A continuous narrative connects the earliest application of probability and statistics in gambling and insurance to the most recent forays into law, medicine, polling and baseball. Separate chapters explore the theoretical and methodological impact in biology, physics and psychology. Themes recur - determinism, inference, causality, free will, evidence, the shifting meaning of probability (...) - but in dramatically different disciplinary and historical contexts. In contrast to the literature on the mathematical development of probability and statistics, this book centres on how these technical innovations remade our conceptions of nature, mind and society. Written by an interdisciplinary team of historians and philosophers, this readable, lucid account keeps technical material to an absolute minimum. It is aimed not only at specialists in the history and philosophy of science, but also at the general reader and scholars in other disciplines. (shrink)

Francis Bacon, the English philosopher, statesman and jurist, is best known for developing the empiricist method which forms the basis of modern science. Bacon's writings concentrated on philosophy and judicial reform. His most significant work is the Instauratio Magna comprising two parts - The Advancement of Learning and the Novum Organum. The first part is noteworthy as the first major philosophical work published in English. James Spedding and his co-editors arranged this fourteen-volume edition, published in London between 1857 and 1874, (...) not in chronological order but by subject matter, so that different volumes would appeal to different audiences. The material is divided into three parts: philosophy and general literature; legal works; and letters, speeches and tracts relating to politics. Volume 14, published in 1874, contains Bacon's papers from 1619 until his death, including his will, papers about his impeachment, and his treatise on English laws. (shrink)

Francis Bacon, the English philosopher, statesman and jurist, is best known for developing the empiricist method which forms the basis of modern science. Bacon's writings concentrated on philosophy and judicial reform. His most significant work is the Instauratio Magna comprising two parts - The Advancement of Learning and the Novum Organum. The first part is noteworthy as the first major philosophical work published in English. James Spedding and his co-editors arranged this fourteen-volume edition, published in London between 1857 and 1874, (...) not in chronological order but by subject matter, so that different volumes would appeal to different audiences. The material is divided into three parts: philosophy and general literature; legal works; and letters, speeches and tracts relating to politics. Volume 9, published in 1862, contains letters and political writings from 1595 to 1601, including papers relating to the treason trial of Robert Devereux, Earl of Essex. (shrink)

Despite the alarming drop in numbers of students studying science throughout the Western world today there is no more important subject in our time than science broadly construed, and these three books provide some of the reasons. Their diversity indicates the shape of the debates occurring about the scientist in Western culture, science's tortured philosophical realism and representation as troubled categories, and, most predictably, life on the screen in the age of the Internet.

The threat of ecological collapse is increasingly becoming a reality for the world’s populations, both human and nonhuman; addressing this global challenge requires enormous cultural creativity and demands a diversity of perspectives, especially from the humanities. Theology and Ecology Across the Disciplines draws from a variety of academic disciplines and positions in order to explore the role and nature of environmental responsibility, especially where such themes intersect with religious or theological viewpoints. Covering disciplines such as history, philosophy, literature, politics, (...) peace studies, economics, women’s studies, and the ecological sciences as well as systematic and moral theology, the contributors emphasize how these positions have begun to develop distinct perspectives on urgent ecological issues, as well as pointing toward specific practices at the local and international level. This volume provides a multidisciplinary point of departure for urgent conversations on environmental responsibility that resist simplistic solutions. Rather, the contributors highlight the complex nature of modern ecology, and suggest creative ways forward in the situation of an apparently intractable global problem. (shrink)

This edited collection discusses phenomenological critiques of formalism and their relevance to the problem of responsibility and the life-world. The authors deal with themes of formalisation of knowledge in connection to the life-world, the natural world, the history of science and our responsibility for both our epistemic claims and the world in which we live. Readers will discover critiques of formalisation, the life-world and responsibility, and a collation and comparison of Patočka's and Husserl's work on these themes. (...) Considerable literature on Husserl is presented here and the two themes of epistemic responsibility and the life-world are discussed together. This work specifically emphasises the interrelatedness of these existential aspects of his work - self-responsibility and the crisis - as not only epistemological, but also related to human life. This volume also introduces Jan Patočka to English-speaking readers as a phenomenologist in his own right. Patočka shows us, in particular, the significance of the modern abyss between our thinking and the world. Readers will discover that this abyss is of concern for our everyday experience because it leads to a rupture in our understanding of the world: between the world of our living and its scientific construct. We see that Patočka continually emphasised the relevance of Husserl's work to existential questions relating to human responsibility and the life-world, which he admits is left largely implicit in Husserl's work. This edited collection will spark discussion on the question of responsibility against the backdrop of formalised knowledge which is increasingly inaccessible to human understanding. Despite the complexity of some of the analysed ideas, the authors discuss these themes in a clear and readable way. This work is scholarly, exact in its discussion and authoritative in its reading, but at the same time accessible to anyone motivated to understand these debates. (shrink)

Francis Bacon, the English philosopher, statesman and jurist, is best known for developing the empiricist method which forms the basis of modern science. Bacon's writings concentrated on philosophy and judicial reform. His most significant work is the Instauratio Magna comprising two parts - The Advancement of Learning and the Novum Organum. The first part is noteworthy as the first major philosophical work published in English. James Spedding and his co-editors arranged this fourteen-volume edition, published in London between 1857 and 1874, (...) not in chronological order but by subject matter, so that different volumes would appeal to different audiences. The material is divided into three parts: philosophy and general literature; legal works; and letters, speeches and tracts relating to politics. Volume 10, published in 1868, contains Bacon's letters and political writings from 1601 to 1607. Of note is Bacon's support of the union of England and Scotland. (shrink)

Islamic polities of the classical period recognized the importance of seaweeds in their daily life. Their men of science, craftsmen, and navigators used them for medicinal purposes, manufacturing, and navigation. The agar components were used in treating pathological conditions such jaundice, spleen, kidney and skin ailments, and malignancies. As food, we stress that our conclusions derive from Qur'ān-based commentaries and Muslim religious law that encouraged seafaring and exploiting the resources of the sea. Concerning navigation, sailors could identify coastal trunk (...) routes, shallows, and various marine phenomena; shipwrights used agar compounds as a protective coating against the Greek Fire. Like their Greco-Roman counterparts, Muslim physicians, chemists, botanists, and professional sailors of this period were acquainted with numerous species of seaweeds and could appreciate the actual scientific importance of each type as well as the aquatic environment where these species lived and developed. Their scholarly literature consists of several generic Arabic and Arabicized terms to denote seaweeds and the terms variations appeared to be physical rather than linguistic. (shrink)

The Life of Voltaire delves into the profound influence of Voltaire's ideas on the betterment of humanity during the eighteenth century. In an era when France was dominated by the authority of the Catholic Church, which stifled science, literature, and freedom, Voltaire stood as a singular force. This book explores how he fearlessly confronted the Church's intolerance, cruelty, and suppression of basic rights. Drawing from a diverse range of French and English sources on Voltaire, and enriched by extensive (...) research, the book not only presents a compelling biography but also offers glimpses into the lives of key eighteenth-century figures who crossed paths with Voltaire. While accessible to general readers, this book provides in-depth insights into Voltaire's philosophical, religious, and literary contributions, examining his most significant works. Notably, it sheds light on his transformation from a literary giant into a staunch advocate for victims of injustice and a vocal opponent of the Catholic Church's dogmatism in the later years of his life. The book is a captivating journey through history, showcasing the enduring relevance of Voltaire's ideas and his pivotal role in shaping modern concepts of human rights and intellectual freedom. (shrink)

Using animals for scientific research is a highly contentious issue that Continental philosophers engaging with 'the animal question' have been rightly accused of shying away from. Now, Wahida Khandker asks whether Continental approaches to animality and organic life will make us reconsider our treatment of non-human animals. By following its historical and philosophical development, she argues that the concept of 'pathological life' as a means of understanding organic life as a whole plays a pivotal role in refiguring (...) the human-animal distinction. She explores the significance of this across philosophy and the life sciences through the work of a number of key thinkers of life and process, from Henri Bergson to Donna Haraway. (shrink)

In this new study, Cristina Chimisso explores the work of the French Philosopher of Science, Gaston Bachelard by situating it within French cultural life of the first half of the century. The book is introduced by a study - based on an analysis of portraits and literary representations - of how Bachelard's admirers transformed him into the mythical image of the Philosopher, the Patriarch and the 'Teacher of Happiness'. Such a projected image is contrasted with Bachelard's own conception of (...) philosophy and his personal pedagogical and moral ideas. This pedagogical orientation is a major feature of Bachelard's texts, and one which deepens our understanding of the main philosophical arguments. The primary thesis of the book is based on the examination of the French educational system of the time and of French philosophy taught in schools and conceived by contemporary philosophers. This approach also helps to explain Bachelard's reception of psychoanalysis and his mastery of modern literature. _Gaston Bachelard: Critic of Science and the Imagination_ thus allows for a new reading of Bachelard's body of work, whilst at the same time providing an insight into twentieth century French culture. (shrink)

The biology of early life adversity explores how social experiences early in life affect physical and psychological health and well-being throughout the life course. In our previous work, we argued that narratives emerging from and about this research field tend to focus on harm and lasting damage with little discussion of reversibility and resilience. However, as the Science and Technology Studies literature has demonstrated, scientific research can be actively taken up and transformed as it moves through (...) social worlds. Drawing on fieldwork with actors in education and juvenile corrections in the US Pacific Northwest, we found that they employed the biology of early life adversity not only to promote prevention but also to argue for changes within their own institutions that would allow them to better serve children and youth who have experienced adversity and trauma. Our study shows that biosocial narratives are neither inherently liberatory nor inherently oppressive but that the situated narrative choreographies in which they are enrolled are essential for their political effects. In our case, we show how these biosocial narratives have been articulated with knowledge and practices from restorative justice and trauma-informed care to reimagine the social meaning of the biology of early life adversity. (shrink)

The rise of cognitive neuroscience is the most important scientific and intellectual development of the last thirty years. Findings pour forth, and major initiatives for brain research continue. The social sciences have responded to this development slowly--for good reasons. The implications of particular controversial findings, such as the discovery of mirror neurons, have been ambiguous, controversial within neuroscience itself, and difficult to integrate with conventional social science. Yet many of these findings, such as those of experimental neuro-economics, pose very (...) direct challenges to standard social science. At the same time, however, the known facts of social science, for example about linguistic and moral diversity, pose a significant challenge to standard neuroscience approaches, which tend to focus on "universal" aspects of human and animal cognition. A serious encounter between cognitive neuroscience and social science is likely to be challenging, and transformative, for both parties. Although a literature has developed on proposals to integrate neuroscience and social science, these proposals go in divergent directions. None of them has a developed conception of social life. This book surveys these issues, introduces the basic alternative conceptions both of the mental world and the social world, and show how, with sufficient modification, they can be fit together in plausible ways. The book is not a "new theory " of anything, but rather an exploration of the critical issues that relate to the social aspects of cognition which expands the topic from the social neuroscience of immediate interpersonal interaction to the whole range of places where social variation interacts with the cognitive. The focus is on the conceptual problems produced by any attempt to take these issues seriously, and also on the new resources and considerations relevant to doing so. But it is also on the need for a revision of social theoretical concepts in order to utilize these resources. The book points to some conclusions, especially about how the process of what was known as socialization needs to be understood in cognitive science friendly terms. But there is no attempt to resolve the underlying issues within cognitive science, which will doubtless persist. (shrink)

Towards biodeconstruction -- Between life and death: différance -- The absolute programme -- The text and the living -- Between life and death: the bond -- Beyond life death: autoimmunity -- Living on: the arche-performative.

In the context of the mandated phaseout of methyl bromide, California’s strawberry industry has increased its use of chloropicrin, another soil fumigant that has long been on the market. However, due to its 2010 designation as a toxic air contaminant, the US Environmental Protection Agency and California’s Department of Pesticide Regulation have developed enhanced application protocols to mitigate exposures of the chemical to bystanders, nearby residents, and farmworkers. The central feature of these mitigation technologies are enhanced buffer zones between treated (...) fields and nearby buildings. Not only do buffer zones inherently privilege neighbors over farmworkers, but the determinations of the size of these buffer zones are also based on acceptable threshold levels and probabilities that allow significant exposures to those they are designed to protect. Moreover, these protocols require human monitors to detect sensory irritation. While the science and technology studies literature is highly useful for understanding the inextricability of science and politics in developing protective measures and is attentive to what counts as data in setting acceptable thresholds, it tends to overlook that social sorting is intrinsic to such regulation. We thus turn to Foucault’s biopolitics to make sense of regulations that are designed to protect but inherently allow some to become ill. Doing so illuminates how determinations of the bright line are at once technical–political as well as implicit decisions about whose bodies count. (shrink)

In the field of cultural evolution it is generally assumed that the study of culture and cultural change would benefit enormously from being informed by evolutionary thinking. Recently, however, there has been much debate about what this “being informed” means. According to the standard view, an interesting analogy obtains between cultural and biological evolution. In the literature, however, the analogy is interpreted and used in at least three distinct, but interrelated ways. We provide a taxonomy in order to clarify (...) these different meanings. Subsequently, we discuss the alternatives model of cultural attraction theory and memetics, which both challenge basic assumptions of the standard view. Finally, we briefly summarize the contributions to the special issue on Darwin in the Humanities and the Social Sciences, which is the result of a collaborative project between scholars and scientists from the universities of Lille and Ghent. Furthermore, we explain how they add to the discussions about the integration of evolutionary thinking and the study of culture. (shrink)

BackgroundInformed consent forms for clinical research are several and variable at international, national and local levels. According to the literature, they are often unclear and poorly understood by participants. Within the H2020 project CORBEL—Coordinated Research Infrastructures Building Enduring Life-science Services—clinical researchers, researchers in ethical, social, and legal issues, experts in planning and management of clinical studies, clinicians, researchers in citizen involvement and public engagement worked together to provide a minimum set of requirements for informed consent in clinical studies.MethodsThe (...) template was based on a literature review including systematic reviews and guidelines searched on PubMed, Embase, Cochrane Library, NICE, SIGN, GIN, and Clearinghouse databases, and on comparison of templates gathered through an extensive search on the websites of research institutes, national and international agencies, and international initiatives. We discussed the draft versions step-by-step and then we referred to it as the “matrix” to underline its modular character and indicate that it allows adaptation to the context in which it will be used. The matrix was revised by representatives of two international patient groups.ResultsThe matrix covers the process of ensuring that the appropriate information, context and setting are provided so that the participant can give truly informed consent. It addresses the key topics and proposes wording on how to clarify the meaning of placebo and of non-inferiority studies, the importance of individual participants’ data sharing, and the impossibility of knowing in advance how the data might be used in future studies. Finally, it presents general suggestions on wording, format, and length of the information sheet.ConclusionsThe matrix underlines the importance of improving the process of communication, its proper conditions (space, time, setting), and addresses the participants’ lack of knowledge on how clinical research is conducted. It can be easily applied to a specific setting and could be a useful tool to identify the appropriate informed consent format for any study. The matrix is mainly intended to support multicentre interventional randomized clinical studies, but several suggestions also apply to non-interventional research. (shrink)

_Religion and the Rise of Modern Culture_ describes and analyzes changing attitudes toward religion during three stages of modern European culture: the Renaissance, the Enlightenment, and the Romantic period. Louis Dupré is an expert guide to the complex historical and intellectual relation between religion and modern culture. Dupré begins by tracing the weakening of the Christian synthesis. At the end of the Middle Ages intellectual attitudes toward religion began to change. Theology, once the dominant science that had integrated all others, (...) lost its commanding position. After the French Revolution, religion once again played a role in intellectual life, but not as the dominant force. Religion became transformed by intellectual and moral principles conceived independently of faith. Dupré explores this new situation in three areas: the literature of Romanticism ; idealist philosophy ; and theology itself. Dupré argues that contemporary religion has not yet met the challenge presented by Romantic thought. “This beautifully crafted essay by Louis Dupré makes an original contribution to our understanding of the emergence and development of modernity, which dispensing with religion as a governing discourse and form of life, nonetheless attempts to find a place for it in a world sufficiently depleted of meaning and value as to require reenchantment. It supplements Dupré’s two magisterial texts on the topic of the modernity covering the Renaissance and Enlightenment periods, and whets the appetite for the forthcoming volume on Romanticism. Deep learning is worn lightly in this marvelously readable book.” —_Cyril O'Regan, University of Notre Dame_ “A stunning synthesis of Dupré's magisterial intellectual history of modernity and his distinctive and important philosophy of religion.” —_David Tracy, emeritus, The University of Chicago Divinity School_ “Louis Dupre's literate and sweeping review of the fate of religious faith in modern culture will help contemporary readers, who share his closing yearning for ways in which ‘transcendence can be recognized again,’ to appreciate why many of us find a postmodern climate—for better or worse—more conducive to fulfilling that desire. For his dramatic depictions of modernity teach us how different is the culture in which we now live.” —_David Burrell, CSC, Hesburgh Professor Emeritus in Philosophy and Theology, University of Notre Dame_. (shrink)

Hybride der Romantik: Frankenstein, Olimpia und das künstliche Leben. Dieser Beitrag untersucht Vorstellungen über die Möglichkeit der Erzeugung künstlicher Lebewesen in der Zeit der Romantik und die damit verbundenen Ängste am Beispiel zweier fiktionaler Texte: Mary Shelleys Frankenstein und Ernst Theodor Amadeus Hoffmanns Sandmann. Dr. Franksteins Monster und Dr. Spalanzanis Automat verkörpern – auf unterschiedliche Weise – die Möglichkeit einer Wendung wissenschaftlicher Produkte und insbesondere künstlicher Hybride ins Monströse. Ihre Geschichten thematisieren das Grauen, das vom drohenden Kontrollverlust ausgeht und als (...) der modernen Wissenschaft innewohnende Gefahr selbst nach der Zerstörung der monströsen Kreaturen bestehen bleibt. Der Begriff des Unheimlichen, von Ernst Jentsch und Sigmund Freud mit Bezug auf Hoffmanns Sandmann formuliert und 1970 von dem japanischen Robotiker Masahiro Mori als Phänomen „des unheimlichen Tals“ (Uncanny Valley) weiterentwickelt, erlaubt weitere Einblicke in die Frage nach künstlichen Lebewesen und ihre Interaktion mit Menschen. Summary: Hybrids of the Romantic: Frankenstein, Olimpia, and Artificial Life. This essay analyzes fantasies and fears related to the possible creation of artificial humans in two influential pieces of Romantic literature, namely E.T.A. Hoffmann's Der Sandmann and Mary Shelley's Frankenstein. Both the automaton Olimpia and Dr. Frankenstein's monster are hybrid creatures. These dystopian figures represent the Romantic fear of the loss of control over the outcome of human endeavour, they symbolize the dangers immanent in modern science and technology. As hybrids, Olimpia and Frankenstein's monster are capable of breaking apparently unpenetrable boundaries, such as those between human and non‐human, and between life and death. As such, these creatures become “unheimlich” (uncanny), a critical term developed by Ernst Jentsch and Sigmund Freud, who directly referred to Hoffmann's Sandman. The term “uncanny” was further developed by the Japanese roboticist Masahiro Mori in the 1970s. Mori's investigation of human responses to androids (“Uncanny Valley”), shows the persistence of doubts and fears surrounding artificial humans far beyond the Romantic times, and opens new questions related to the issues of creation, reproduction, hybrids, hubris and gender. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:The Human Revolution and the Adaptive Function of LiteratureJoseph CarrollIBefore the advent of purely culturalist ways of thinking in the early decades of the twentieth century, the idea of "human nature" was deeply ingrained in the literature and the humanistic social theory of the West.1 In the past three decades, ethology, sociobiology, and evolutionary psychology have succeeded in making the idea of "human nature" once again a commonplace (...) of public discourse, but the actual shape and content of human nature, even among Darwinian social scientists, remains controversial. Human nature is the product of evolution, and for Darwinians, concepts about the structure of human nature are necessarily bound up with concepts about the course of human evolution. My purpose in this essay will be to examine two chief alternatives in the current Darwinian understanding of human evolution and human nature, to advocate one of these alternatives, and to assess its implications for Darwinian literary study. One alternative can be identified with evolutionary psychology, and the other, the one I shall advocate, with evolutionary anthropology and cognitive archaeology. For the sake of economy, I shall refer to the former as the EP model and to the latter as the EACA model.In the late 1980s and early 1990s, the main theoretical controversy in Darwinian social science was that between the sociobiologists and Darwinian anthropologists, on the one side, and the evolutionary psychologists on the other. The point at issue was whether "fitness maximization" or the desire to maximize reproductive success could serve as a direct motive in human behavior. The sociobiologists tended to assume it could; the [End Page 33] evolutionary psychologists instead insisted that fitness maximization was mediated through "proximal mechanisms" such as the male desire for sex and the female desire to acquire resources from male sexual partners. In the arena of received professional opinion, the evolutionary psychologists won this debate, and evolutionary psychology is now the mainstream, establishment creed in Darwinian social science.2 Its hegemony is evidenced by a flood of popular expositions and textbooks. The majority of these expositions give little evidence that the authors are themselves alert to the speculative character of the fundamental concepts of their creed, and the chief tenets of the creed have often been reiterated in a naively uncritical way.The chief tenets of orthodox evolutionary psychology are (a) that the structure of the human mind stabilized during the Pleistocene (beginning about 1.6 million years ago); (b) that the human mind is "modular" in character—consisting of discrete bits of dedicated neural circuitry automatically activated by environmental releasers; (c) that human cognitive aptitudes and motivational structures are firmly adapted to the hunter-gatherer life-style of the Pleistocene—the "environment of evolutionary adaptedness" or EEA; and (d) that the adaptation to Pleistocene conditions carries with it, as a necessary corollary, a "mismatch" between the adapted human mind and all cultural ecologies more complex than that of hunter-gatherers. The core concept, the idea on which all the others depend, is that of the EEA:What we think of as all of human history—from, say, the rise of the Shang, Minoan, Egyptian, Indian, and Sumerian civilizations—and everything we take for granted as normal parts of life—agriculture, pastoralism, governments, police, sanitation, medical care, education, armies, transportation, and so on—are all the novel products of the last few thousand years. In contrast to this, our ancestors spent the last two million years as Pleistocene hunter-gatherers, and, of course, several hundred million years before that as one kind of forager or another. These relative spans are important because they establish which set of environments and conditions defined the adaptive problems the mind was shaped to cope with: Pleistocene conditions, rather than modern conditions.3For evolutionary psychologists, the difference between our Paleolithic ancestors and ourselves is a difference not in anatomical and neurological character but only in external "circumstances." In the EP model, the structure of the human mind at the present time and the structure [End Page 34] of the mind of, say, half a million years ago, would be the same. They would be equally the mind of the Pleistocene.The EP model of... (shrink)