BackgroundThe proper and ethical inclusion of PWLHIV and their young children in research is paramount to ensure valid evidence is generated to optimize treatment and care. Little empirical data exists to inform ethical considerations deemed most critical to these populations. Our study aimed to systematically review the empiric literature regarding ethical considerations for research participation of PWLHIV and their young children.MethodsWe conducted this systematic review in partnership with a medical librarian. A search strategy was designed and performed within the following (...) electronic databases: Ovid MEDLINE, Embase and CINAHL. We screened titles and abstracts using the following inclusion criteria: (1) a study population of PWLHIV or children under 5 years of age; and (2) collection of qualitative or quantitative data regarding ethics of research participation. Excluded were reviews, commentaries, policy statements, clinical care-related ethics concerns, abstracts, case studies, or studies unrelated to HIV research. Studies were appraised for quality, data were extracted, and studies were qualitatively analyzed using a principle-based ethical framework within the Belmont Report.ResultsOf the 7470 titles identified, 538 full-text articles were reviewed for eligibility and only three articles met full criteria for inclusion within this review. While we allowed for inclusion of studies involving young children born to mothers with HIV, only articles focused on PWLHIV were identified. Within the results of these studies, four themes emerged: (1) adequacy of informed consent; (2) consideration of paternal involvement; (3) balancing risks; and (4) access to research and treatment. A strength of this review is that it included perspectives of international research investigators, community leaders, and male partners. However, only two studies collected empiric data from PWLHIV regarding their experiences participating in researchConclusionResearchers and funding agencies should be aware of these considerations and appreciate the value of and critical need for formative research to ensure clinical trials involving PWLHIV promote ethical, well-informed research participation and, ultimately, improve care outcomes. More research is needed to create a comprehensive ethical framework for researchers when conducting studies with PWLHIV. (shrink)

Volume 20, Issue 5, June 2020, Page 72-74.

Over the last several years, democratic citizens and theorists have been grappling with an upsurge in political commentary on the crisis and decline of democratic legitimacy around the world. Increasingly, theoretical attention is turning from the philosophical justification of ambitious moral ideals of democracy, to the interpretation of potentials within existing political practice for democratic renewal and repair. This review article examines three new books at the forefront of this theoretical turn towards engagement with the real-world political dynamics of democratic (...) crisis and revival: Open Democracy by Hélène Landemore; Hope for Democracy by John Gastil and Katherine Knobloch; and Mending Democracy by Carolyn Hendriks, Selen Ercan and John Boswell. It begins by surveying the new contributions of these books – highlighting the importance all attribute to creative political agency as a source of revival in democratic practice. It then discusses several questions left unresolved by these books – concerning the problem of democratic legitimacy, the normativity of democratic standards and the power dynamics undergirding democratic agency – which jointly mark out an important agenda for future theoretical work on pathways out of democratic crisis. (shrink)

_Varieties of Things: Foundations of Contemporary Metaphysics_ is about some of the most fundamental kinds of things that there are; the things that we encounter in everyday experience. A book about the things that we encounter in everyday experience. Contains a thorough and accessible discussion of the nature and aims of metaphysics. Examines a wide range of ontological categories, including both particulars and universals. Mounts a forceful and persuasive case for anti-reductionism.

In this chapter, I examine Lewis's ideas about ontological innocence, ontological commitment and double-counting, in his discussion of composition as identity in Parts of Classes. I attempt to understand these primarily as epistemic or methodological claims: how far can we get down this route without adopting radical metaphysical theses about composition as identity?

There are moments when things suddenly seem strange - objects in the world lose their meaning, we feel like strangers to ourselves, or human existence itself strikes us as bizarre and unintelligible. Through a detailed philosophical investigation of Heidegger's concept of uncanniness (Unheimlichkeit), Katherine Withy explores what such experiences reveal about us. She argues that while others (such as Freud, in his seminal psychoanalytic essay, 'The Uncanny') take uncanniness to be an affective quality of strangeness or eeriness, Heidegger uses (...) the concept to go beyond feeling uncanny to reach the ground of this feeling in our being uncanny. -/- "Heidegger on Being Uncanny" answers those who wonder whether human existence is fundamentally strange to itself by showing that we can be what we are only if we do not fully understand what it is to be us. This fundamental finitude in our self-understanding is our uncanniness. In this first dedicated interpretation of Heidegger's uncanniness, Withy tracks this concept from his early analyses of angst through his later interpretations of the choral ode from Sophocles's Antigone. Her interpretation uncovers a novel and robust continuity in Heidegger's thought and in his vision of the human being as uncanny, and it points the way toward what it is to live well as an uncanny human being. (shrink)

Not a full treatment of Newton’s scientific method, this book discusses his optical research only in passing (342–43). Its subtitle better indicates its scope: it focuses narrowly on the argument for universal gravitation in Book III of the Principia. The philosophical project is to set out an “ideal of empirical success” realized by the argument. Newton claims his method is to “deduce” propositions “from phenomena.” On Harper’s interpretation Newton’s phenomena are patterns of data, which are used to measure “parameters” by (...) which the theory explains them. An example is Kepler’s Area Rule. Its fit to the data confirms the hypothesis that the force maintaining a body in orbit is directed toward the .. (shrink)

In this chapter I explore how epistemic injustice (as discussed by Miranda Fricker) can arise in connection with knowledge how. I attempt to bypass the question of whether knowledge how is a type of propositional knowledge, and instead focus on some distinctive ways in which knowledge how is sometimes sought, identified or ignored.

Many philosophers have attempted to provide a solution to the paradox of fiction, a triad of sentences that lead to the conclusion that genuine emotional responses to fiction are irrational. We suggest that disagreement over the best response to this paradox stems directly from the formulation of the paradox itself. Our main goal is to show that there is an ambiguity regarding the word ‘exist’ throughout the premises of the paradox. To reveal this ambiguity, we display the diverse existential commitments (...) of several leading theories of emotion, and argue that none of the theories we consider are committed to notions of ‘exist’ employed by the paradox. We conclude that it is unclear whether or not there remains a paradox of fiction to be solved—rather than to be argued for—once this ambiguity is addressed. (shrink)

In this paper, I utilise the tools of analytic philosophy to amalgamate mono-causal and multi-causal theories of disease. My aim is to better integrate viral and socio-economic explanations of AIDS in particular, and to consider how the perceived divide between mono-causal and multi-causal theories played a role in the tragedy of AIDS denialism in South Africa in the early 2000s. Currently, there is conceptual ambiguity surrounding the relationship between mono-causal and multi-causal theories in biomedicine and epidemiology. Mono-causal theories focus on (...) single, typically microbial, sources of illness and are most concerned with infectious diseases. By contrast, multi-causal theories allow for multiple factors to underpin a disease’s aetiology, including socio-economic and behavioural factors, and they usually focus on chronic non-communicable diseases. However, if these theories are taken to be strictly distinct, this prevents the inclusion of both microbial and socio-economic factors in a single explanation of any particular disease. This strict distinction became a problem when trying to explain the disproportionate prevalence of AIDS in southern Africa and ultimately contributed to the tragedy of AIDS denialism in South Africa. In tandem with viewing how the perceived divide between multi-causal and mono-causal theories underpinned AIDS denialism, I examine Thabo Mbeki’s specific role, while acknowledging that AIDS is being deprioritised on a broader international level. Overall, I will demonstrate that any long-term plan to eliminate AIDS will require viral and socio-economic factors to be considered simultaneously and that such a theoretical approach requires a clearer understanding of the underlying concepts of disease aetiology. (shrink)

This paper explores the conscious visual experience of seeing race. In everyday occurrences, racialized seeing involves the capacity for a subject to simply “see” that someone she encounters belongs to a racial category. I bridge research in analytic philosophy of perception and accounts from phenomenologists and critical race theorists on the lived experience of racialized seeing. I contend that we should not trust our visual experiences of racialized seeing because they provide, at best, incomplete information on a target’s racial identity. (...) I make a case for a version of perceptual learning that I think both captures actual experiences of racialized seeing and is empirically plausible. Finally, I follow work of critical race theorists in suggesting that normative constraints surrounding racial identity and privilege are built into our experiences of racialized seeing. Both types of racialized seeing are subject to social norms and practices and, thus, aid in perpetuating racial hierarchies. (shrink)

It is widely accepted that physicalism faces its most serious challenge when it comes to making room for the phenomenal character of psychological experience, its so-called what-it-is-like aspect. The challenge has surfaced repeatedly over the past two decades in a variety of forms. In a particularly striking one, Frank Jackson considers a situation in which Mary, a brilliant scientist who knows all the physical facts there are to know about psychological experience, has spent the whole of her life in a (...) black and white room. He asks, What will happen when Mary is released from her black and white room or is given a colour television monitor? Will she learn anything or not? It seems just obvious that she will learn something about the world and our visual experience of it. But then it is inescapable that her previous knowledge was incomplete. But she had all the physical information. (Jackson 1986: 130). (shrink)

Our day-to-day experience of the world regularly brings us into contact with middlesized objects such as apples, dogs, and other human beings. These objects possess observable properties, properties that are available or accessible to the unaided senses, such as redness and roundness, as well as properties that are not so available, such as chemical ones. Both of these kinds of properties serve as valuable sources of information about our familiar middle-sized objects at least to the extent that they enable us (...) to understand the behaviours of those objects and their effects on each other and on us. I see the apple on the table before me, and in doing so I see its redness, its roundness, and so on. I do not see, but know that it has, a certain chemical constitution. The knowledge gained of the apple by means of both properties tells me something about the nature of that apple. In general, most, if not all, of the properties that objects in the observable world possess serve as the basis of our knowledge of such objects. But the subject-predicate form of much of our discourse and thought about objects suggests that substances are one kind of thing, properties another. We use subject terms such as names to identify objects, predicate terms to attribute properties to them. What, then, is it for an object to have a property? And what is the relation between an object and its properties? (shrink)

This paper considers whether individual companies have an ethical obligation to label their Genetically Modified (GM) foods. GM foods and ingredients pervade grocery store shelves, despite the fact that a majority of North Americans have worries about eating those products. The market as whole has largely failed to respond to consumer preference in this regard, as have North American governments. A number of consumer groups, NGO’s, and activist organizations have urged corporations to label their GM products. This paper asks whether, (...) in such a situation, individual corporations can be ethically required to take such unilateral action. We argue that they cannot. Given the lack of solid evidence for any risk to human health, and the serious market disadvantage almost surely associated with costly unilateral action, no individual company has an ethical obligation to label its GM foods. (shrink)

This article focuses on a potentially perplexing aspect of our interactions with pictorial representations : in some cases, it seems that visual representations can play tricks on our cognitive faculties. We may either come to believe that objects represented in pictures are real or perhaps perceive them as such. The possibility of widespread pictorial illusions has been oft discussed, and discarded, in the aesthetics literature. I support this stance. However, the nature of the illusion is more complicated than is usually (...) considered. I argue that there are five different types of potential illusions and present reasons for rejecting each. I also explore in detail the most persistent illusion: the “object recognition perceptual illusion thesis,” which states that we undergo a perceptual illusion while viewing pictorial representations simply in virtue of seeing objects in the representation. I contend that a rejection of this thesis depends on the nature of perceptual content, an issue with far-reaching consequences in aesthetics. (shrink)

This paper responds to comments on the paper "True Faith: Against Doxastic Partiality about Faith (in God and Religious Communities) and in Defense of Evidentialism" (Australasian Philosophical Review). I begin with some clarifications on faith and its normativity (section 1). I then zero in on doxastic normativity (section 2), where an ideological rift emerges between evidentialism and partialist critiques (section 3). I then discuss evidentialist reason and its relationship to objectivity (section 4), and the sort of norms at issue (section (...) 5). (shrink)

This article considers two prominent, competing approaches to defining the scope of business responsibility for human rights. The first approach advocates extension of business responsibility beyond the boundaries of the enterprise to encompass broader ‘spheres of influence’. The second approach advocates a business ‘responsibility to respect’ human rights. Building on a critical evaluation of these competing accounts of business responsibility, this article outlines a modified account, referred to as a framework of ‘spheres of responsibility’. On such an account, business responsibility (...) for human rights outcomes is conceptualised not only in relation to direct ‘harms’ imposed by business, but also in relation to corporate influence over broader relationships and institutions that shape and constrain the substantive realisation of human rights. (shrink)

In his reflections on his adolescent theft of a neighbor’s pears, Augustine first claims that he did it just because it was wicked. But he then worries that there is something unacceptable in that claim. Some readers have found in this account Augustine’s rejection of the principle that all voluntary action is done for the sake of some perceived good. I argue that Augustine intends his case to call the principle into question, but that he does not ultimately reject it. (...) His careful and resourceful analysis of the motivations of his theft adds subtlety to his own understanding of voluntary action and allows hirn to introduce an important component of his general account of sin, namely, that it essentially involves prideful self-assertion in imitation of God. (shrink)

Ignorance can excuse otherwise blameworthy action, but only if the ignorance itself is blameless. One way to avoid culpable ignorance is to pay attention when epistemic peers disagree. Expressed disagreements place an obligation on the agent to pay attention when an interlocutor disagrees, or risk culpable ignorance for which they might later be found blameworthy. Silence, on the other hand, is typically taken as assent. But in cases of suppressed disagreement, the silenced interlocutor has information that could save the agent (...) from ignorance in scenarios where that ignorance might lead to harmful action, and silence does not actually indicate assent. The problem is further complicated because the agent might not be aware of the fact that a silenced interlocutor has information that could prevent ignorance, and consequent harmful action. In this paper, I provide a new account of excuses from ignorance in situations of suppressed disagreement. I do this in the context of two cases; Kelly’s hypothetical case of the Tyrannical Dictator, and the real-world case of former South African President Thabo Mbeki and his AIDS denialist policies in the late 1990s and early 2000s. (shrink)

This volume explores the ethical dimensions of a wide selection of philosophical and theological topics in Aquinas's texts.

The main goal of part 1 is to challenge the widely held view that Poincaré orders the sciences in a hierarchy of dependence, such that all others presuppose arithmetic. Commentators have suggested that the intuition that grounds the use of induction in arithmetic also underlies the conception of a continuum, that the consistency of geometrical axioms must be proved through arithmetical induction, and that arithmetical induction licenses the supposition that certain operations form a group. I criticize each of these readings. (...) More fully, I argue that the justification Poincaré offers for the use of the group notion in geometry appears to extend to set-theoretic notions that would suffice to put arithmetic on a logical foundation, thus undermining his own case for the necessity of intuition in arithmetic. In part 2, I offer an interpretation of intuition’s role on which it justifies the use of group-theoretic, but not set-theoretic, notions. (shrink)

There is a consistent and simple interpretation of the quantum theory of isolated systems. The interpretation suffers no measurement problem and provides a quantum explanation of state reduction, which is usually postulated. Quantum entanglement plays an essential role in the construction of the interpretation.

This paper explores the role of the Ciceronian tradition in the radical religious discourse of John Toland . Toland produced numerous works seeking to challenge the authority of the clergy, condemning their ‘priestcraft’ as a significant threat to the integrity of the Commonwealth. Throughout these anticlerical writings, Toland repeatedly invoked Cicero as an enemy to superstition and as a religious sceptic, particularly citing the theological dialogues De Natura Deorum and De Divinatione. This paper argues that Toland adapted the Ciceronian tradition (...) so that it could function as an active influence on the construction of his radical discourse. First, it shows that Toland championed a particular interpretation of Cicero's works which legitimised his use of Cicero in this rational context. Then, it shows the practical manifestations of this interpretation, examining the ramifications for how Toland formed three important facets of his campaign against priestcraft: his identification of priestcraft as a superstition; his argument for a rational religion in which priestcraft could play no role; and his portrayal of anticlericalism as a service to the Commonwealth. (shrink)

Hans C. Ohanian 1 claims to “defeat” the conventionalist thesis of clock synchronization using an argument based on dynamics. My aim here is to show that his argument does not succeed.

We outline a simple development of special and general relativity based on the physical meaning of the spacetime interval. The Lorentz transformation is not used.

There is no indication of time dilation of clocks or of length contraction of rods in Marzke and Wheeler's clock or in Desloge's metrosphere.

"Permanent Things reminds us that some of the century's most imaginative minds - G. K. Chesterton, T. S. Eliot, C. S. Lewis, Dorothy Sayers, and Evelyn Waugh - were profoundly at odds with the secularist spirit of the age, seeing progressive enlightenment as ushering in, not a millennium of perfect freedom, but a Waste Land whose inhabitants - Waugh's "vile bodies," Eliot's "hollow men," Lewis's "men without chests" - can find refuge from their boredom and anomie only in the ceaseless (...) acquisition of things or in the consoling illusions of pseudo religions - "distracted from distraction by distraction," as Eliot memorably put it." "How does one explain the desolation of a world which, though richly endowed with material comforts, is mentally and spiritually impoverished? The essayists here are united, as were their subjects, by a need to try to answer this question. Modern man's poverty of spirit, visible alike in so much of his art and architecture, his literature and philosophy and political science, reflects his loss of any good reasons for living - his loss of the Permanent Things." "The Christian writers whose work is eloquently interpreted in this book repay our attention for at least two reasons. First is their ability to sharpen our awareness of what, by any previous civilized standards, must be called the abnormal condition of modern man. For all the writers treated in this book, it was never enough to simply capture the spiritual aridity of modern life. It was also necessary to speak of a moral order that may yet be restored by the expressive power and beauty of the written word."--BOOK JACKET.Title Summary field provided by Blackwell North America, Inc. All Rights Reserved. (shrink)

Dozens of records attest to the fact that during the mid-seventeenth century politicized public nudity or “going naked as a sign” as it was known to early modernsubjects proliferated. This practice captured so much popular attention that Sir Charles Sedley along with other royalist libertines notoriously stripped in front of 1,000 spectators in 1663 and delivered a mock sermon in a grotesque parody of religious sectarians. I examine Quaker approaches to signification, focusing on their deployment of incarnational signs to advance (...) a revolutionary challenge to the empty reified signs of a burgeoning secular and commercial culture. Although both men and women went naked as a sign, the creative potential of women’s bodies, I argue, constituted a doubly-threatening specter to observers. In the midst of a period that witnessed what James Holstun has characterized as “the sundering of human life from providential history,” women openly exposed their bodies in order to visually underscore their creative potential and to call attention to the sacred and incalculable promise of life itself. (shrink)

This article represents conversations with the American composer Libby Larsen in which she described her beliefs about music, music education, and the dilemmas that our current system faces as we seek to provide relevant and meaningful music education to our students. Our conversation explores such topics as cognitive psychology, music theory, cultural practices and developments in American culture, and current music education practices. Larsen brought up many questions about music education in America, providing some suggestions for the future and posing (...) problems for which the solution may require a great deal of imagination by music education teachers. The article is structured as a Socratic dialogue, in which Larsen constructs an inductively strong argu- ment for making radical changes to current music education practice. (shrink)

Nanotechnology research is beginning to see widespread coverage in the media and popular science literatures, but discussions of hopes and fears about nanotechnology have already become polarised into utopian and dystopian visions. More moderate discussions focus on the near-term applications of nanotechnologies, and on potential benefits and harms. However, in exploring the social and ethical implications of nanotechnology, important lessons should be learned from experiences in other fields. In particular, studies of the ethical, legal, and social issues of genetics research (...) have successfully mapped out many of the issues that arise when new technologies are deployed. It is our contention that, for the most part, the ethical and social issues arising in nanomedicine are not altogether new, and thus do not require novel ethical principles or frameworks, nor a massive investment in ‘NELSI’ research. Instead, what is needed is support for the development of a culture of ethics amongst scientists and clinicians, basic scientific and medical knowledge for bioethicists, and a social competency for citizens to participate actively in debates about the implications of new technologies in general. (shrink)

There has been a distinct trend in modern thought to be deeply suspicious and critical of the human mind's ability to gain genuine access to any reality that transcends the world or the mind. As such, much modern reflection on the mind's relationship to a transcendent God has either banished God from the realm of the cognitively accessible or found ways to evacuate God of his transcendence, and reduce God to a concept or idea in the mind. In this book, (...) I directly challenge negative modern understandings of the mind's relationship to God, and advance the provocative claim that the human mind is not "bounded" on the outside but actually remains "open" to the world and to God. As such, the mind is able to know the world and God with varying degrees of objectivity. I turn to Thomas Aquinas in order to explicate as well as defend important claims that Aquinas makes about human cognition as well as our knowledge of God. (shrink)

In this article, I address the question why God would create a world with damned human beings in it when (presumably) he could create a better world without damned human beings. Specifically, I explain and defend what I call the “perfection of the universe argument.” According to this argument, which is Augustinian and Thomistic in origin, it is entirely and equally consistent with divine goodness for God to create a world with damned human beings in it or a damnation-free world (...) so long as God ensures that each world is good as a whole. I then respond to two different objections to this argument. Finally, I show how the perfection of the universe argument leaves room for hoping that we live in a world in which no human being is damned and God affords every human being a life that is good as a whole. (shrink)

Health care providers’ interpretation of law can have intended and unintended effects on health care delivery in Canada. At times, health care providers encounter situations where they perceive the law to conflict with their sense of what is most ethically justified. In many cases, these health care providers feel especially torn because they assume that the legal requirements must dictate the decision, and cannot be explored or questioned. We challenge this assumption: the law is not as cut-and-dried as some assume; (...) therefore, its significance to health care decisions should be carefully considered. Within a systematic ethics process, legal considerations can be a source of values and information and can create opportunities for further dialogue. This approach is justified because it appropriately reflects the relationship of the law to ethics. This way of thinking about the law and ethics also avoids potentially harmful consequences of legalistic approaches to decision-making, such as breakdowns in communication, adversarial relationships, and a reduction of ethically complex decisions to simple rule following. (shrink)