Ample research links mothers’ postpartum depression (PPD) to adverse interactions with their infants. However, most studies relied on general population samples, whereas a substantial number of women are at elevated depression risk. The purpose of this study was to describe mothers’ interactions with their 6- and 12-month-old infants among women at elevated risk, although with a range of symptom severity. We also identified higher-order factors that best characterized the interactions and tested longitudinal consistency of these factors from 6 to 12 (...) months of infant age. We leveraged data from eight projects across the United States (n = 647), using standardized depression measures and an adaptation of the NICHD Mother-Infant Interaction Scales. Overall, these depression-vulnerable mothers showed high levels of sensitivity and positive regard and low levels of intrusiveness, detachment, and negative regard with their infants. Factor analyses of maternal behaviors identified two overarching factors—“positive engagement” and “negative intrusiveness” that were comparable at 6 and 12 months of infant age. Mothers’ ability to regulate depressed mood was a key behavior that defined “positive engagement” in factor loadings. An exceptionally strong loading of intrusiveness on the second factor suggested its central importance for women at elevated depression risk. Mothers with severe depressive symptoms had significantly more “negative intrusiveness” and less “positive engagement” with their 6-month-old infants than women with moderate or fewer depressive symptoms, suggesting a potential tipping point at which symptoms may interfere with the quality of care. Results provide the foundation for further research into predictors and moderators of women’s interactions with their infant among women at elevated risk for PPD. They also indicate a need for evidence-based interventions that can support more severely depressed women in providing optimal care. (shrink)

We estimate that 208,000 deep brain stimulation (DBS) devices have been implanted to address neurological and neuropsychiatric disorders worldwide. DBS Think Tank presenters pooled data and determined that DBS expanded in its scope and has been applied to multiple brain disorders in an effort to modulate neural circuitry. The DBS Think Tank was founded in 2012 providing a space where clinicians, engineers, researchers from industry and academia discuss current and emerging DBS technologies and logistical and ethical issues facing the field. (...) The emphasis is on cutting edge research and collaboration aimed to advance the DBS field. The Eighth Annual DBS Think Tank was held virtually on September 1 and 2, 2020 (Zoom Video Communications) due to restrictions related to the COVID-19 pandemic. The meeting focused on advances in: (1) optogenetics as a tool for comprehending neurobiology of diseases and on optogenetically-inspired DBS, (2) cutting edge of emerging DBS technologies, (3) ethical issues affecting DBS research and access to care, (4) neuromodulatory approaches for depression, (5) advancing novel hardware, software and imaging methodologies, (6) use of neurophysiological signals in adaptive neurostimulation, and (7) use of more advanced technologies to improve DBS clinical outcomes. There were 178 attendees who participated in a DBS Think Tank survey, which revealed the expansion of DBS into several indications such as obesity, post-traumatic stress disorder, addiction and Alzheimer’s disease. This proceedings summarizes the advances discussed at the Eighth Annual DBS Think Tank. (shrink)

With this third edition of Nelson Goodman's The Structure of Appear ance, we are pleased to make available once more one of the most in fluential and important works in the philosophy of our times. Professor Geoffrey Hellman's introduction gives a sustained analysis and appreciation of the major themes and the thrust of the book, as well as an account of the ways in which many of Goodman's problems and projects have been picked up and developed by others. (...) Hellman also suggests how The Structure of Appearance introduces issues which Goodman later continues in his essays and in the Languages of Art. There remains the task of understanding Good man's project as a whole; to see the deep continuities of his thought, as it ranges from logic to epistemology, to science and art; to see it therefore as a complex yet coherent theory of human cognition and practice. What we can only hope to suggest, in this note, is the b. road Significance of Goodman's apparently technical work for philosophers, scientists and humanists. One may say of Nelson Goodman that his bite is worse than his bark. Behind what appears as a cool and methodical analysis of the conditions of the construction of systems, there lurks a radical and disturbing thesis: that the world is, in itself, no more one way than another, nor are we. It depends on the ways in which we take it, and on what we do. (shrink)

Talk given at a memorial meeting for C. I. Lewis at Harvard University, April 23, 1964.

Required reading at more than 100 colleges and universities throughout North America.

Fundamental Buddhist teachings -- Main features of some western ethical theories -- Teravāda ethics as rule-consequentialism -- Mahāyāna ethics before Śāntideva and after -- Transcending ethics -- Buddhist ethics and the demands of consequentialism -- Buddhism on moral responsibility -- Punishment -- Objections and replies -- A Buddhist response to Kant.

Essays discuss cognition, perception, art, science, truth, metaphor, education, philosophy, and cognitive psychology.

In an essay on performance-enhancing drugs, author Chuck Klosterman (2007) argues that the category of enhancers extends from hallucinogens used to inspire music to steroids used to strengthen athletes—and he criticizes those who would excuse one means of enhancement while railing against the other as a form of cheating: After the summer of 1964, the Beatles started taking serious drugs, and those drugs altered their musical performance. Though it may not have been their overt intent, the Beatles took performance-enhancing drugs. (...) And . . . absolutely no one holds it against them. No one views “Rubber Soul” and “Revolver” as “less authentic” albums, despite the fact that they would not (and probably could .. (shrink)

Vague existence can seem like the worst kind of vagueness in the world, or seem to be an entirely unintelligible notion. This bad reputation is based upon the rumour that if there is vague existence then there are non-existent objects. But the rumour is false: the modest brand of vague existence entailed by certain metaphysical theories of composition does not deserve its bad reputation.

Sometimes it is epistemically beneficial to form a belief on authority. When you do, what happens to other reasons you have for that belief? Linda Zagzebski’s total-preemption view says that these reasons are “preempted”: you still have them, but you do not use them to support your belief. I argue that this situation is problematic, because having reasons for a belief while not using them forfeits you doxastic justification. I present an alternative account of belief on authority, the proper-basing view, (...) which enables the agent to base her belief on as many reasons as she has. A salient result is that the notion of a preemptive reason, useful though it may be in accounting for acting on authority, does not have any place in an account of believing on authority or in epistemology more generally. (shrink)

This cogently argued and richly illustrated book rejects the dichotomy between the God of Abraham and the God of the philosophers to argue that the two are one. In God of Abraham, one of our leading philosophers of religion shows how human values can illuminate our idea of God and how the monotheistic idea of God in turn illuminates our moral, social, cultural, aesthetic, and even ritual understanding. Throughout Goodman draws on a wealth of traditional, philosophical, historical, and anthropological (...) materials, and particularly on a wide range of Jewish sources. He demonstrates how an adequate understanding of the interplay of values with monotheism dissolves many of the longstanding problems of natural theology and ethics and guides us toward a genuinely humanistic moral and social philosophy. (shrink)

Conditional excluded middle (CEM) is the following principe of counterfactual logic: either, if it were the case that φ, it would be the case that ψ, or, if it were the case that φ, it would be the case that not-ψ. I will first show that CEM entails the identity of indiscernibles, the falsity of physicalism, and the failure of the modal to supervene on the categorical and of the vague to supervene on the precise. I will then argue that (...) we should accept these startling conclusions, since CEM is valid. (shrink)

Student nurses’ professional development arises through socialisation in nursing knowledge, values and behaviours. Students are expected to demonstrate compassion; however, compassion is a complex concept, one that creates emotional challenges. A grounded theory study was undertaken to explore student nurse socialisation in compassionate practice. In-depth interviews were undertaken with 19 students in the north of England during 2009–2010, and their concerns and concern management emerged. Students expressed several concerns, one being their emotional vulnerability and uncertainty of the emotional requirements for (...) compassionate practice. A core category of ‘balancing future intentions’ was identified: that students managed feelings of vulnerability and uncertainty through balancing their intentions towards and away from engagement in compassionate practice, depending upon perceived impact on their emotional well-being. The findings are discussed in relation to emotional labour and moral distress, and courage, resilience and self-compassion are explored as a means to enable sustainable compassionate practice. (shrink)

Much attention has been given to the question of ontic vagueness, and the issues usually center around whether certain paradigmatically concrete entities – cats, clouds, mountains, etc. – are vague in the sense of having indeterminate spatial boundaries. In this paper, however, I wish to focus on a way in which some abstracta seem to be locationally vague. To begin, I will briefly cover some territory already covered regarding certain types of “traditional” abstracta and the ways they are currently alleged (...) to be vague. I then wish to discuss two types of “nontraditional” abstracta and the sense in which I think some of these objects are locationally vague. I will next reexamine some of the traditional abstracta and discuss whether any of these objects are locationally vague in the novel way suggested for the nontraditional sorts. I’ll finish by discussing objections, and conclude with some remarks about characterizing the abstract/concrete distinction. (shrink)

There is no concept more central to logic and critical thinking than the concept of an argument. I here address the definition of ‘argument’ in the logical sense of the term and defend the claim that many current proposals, once they are interpreted in a way that makes them sufficiently precise, are extensionally inadequate. Definitions found in some contemporary, prominent critical thinking textbooks will serve as a springboard. I claim that each may be interpreted in an absolutist way or a (...) relativistic way, yet all turn out to be objectionable no matter which route is taken. I finish with a proposal on which the definition of ‘argument’ is an absolutist one, yet one that avoids the problems discussed for the earlier proposals. (shrink)

Multimodal prehabilitation is increasingly recognized as an important component of the pre-operative pathway in oncology. It aims to optimize physical and psychological health through delivery of a series of tailored interventions including exercise, nutrition, and psychological support. At the core of this prescription is a need for considerable health behavior change, to ensure that patients are engaged with and adhere to these interventions and experience the associated benefits. To date the prehabilitation literature has focused on testing the efficacy of devised (...) exercise and nutritional interventions with a primary focus on physiological and mechanistic outcomes with little consideration for the role of behavioral science, supporting individual behavior change or optimizing patient engagement. Changing health behavior is complex and to maximize success, prehabilitation programs should draw on latest insights from the field of behavioral science. Behavioral science offers extensive knowledge on theories and models of health behavior change to further advance intervention effectiveness. Similarly, interventions developed with a person-centered approach, taking into consideration individual needs and preferences will increase engagement. In this article, we will provide an overview of the extent to which the existing prehabilitation literature incorporates behavioral science, as well as studies that have explored patient's attitudes toward prehabilitation. We will go on to describe and critique ongoing trials in a variety of contexts within oncology prehabilitation and discuss how current scientific knowledge may be enhanced from a behavioral science perspective. We will also consider the role of “surgery schools” and detail practical recommendations that can be embedded in existing or emerging clinical settings. (shrink)

We are living in an era of multiple crises, multiple social resistances, and multiple cosmopolitanisms. The post-Cold War context has generated a plethora of movements, but no single unifying ideology or global political program has yet materialized. The historical confrontation between capital and its alternatives, however, continues to pose new possibilities for social and systemic transformations. Critical analysis of ideological divisions among today’s diverse emancipatory and transformative movements is important in order to understand past and present shortcomings, and many continuing (...) difficulties in imagining crisis-free alternative futures. Inspired by a multiplicity of responses from the Global South and the Global North, and by furthering Delanty’s critical cosmopolitanist approach, this article aims to create a new framework for interpreting ‘transformative visions’ that challenge systems of domination embedded in capitalist social relations. The framework is designed to enable the evaluative analysis of such visions, as well as the exploration of embedded ideological obstacles to dialogue and collaboration among them. (shrink)

One of the largest, oldest, and most interesting challenges in health care is the balancing act in which clinicians have generally uncontroversial duties both to individual patients and to communities. Physicians and nurses must — so we teach them — put patients first, and at the same time recognize that individuals are members of communities. Individuals affect the health of communities, and communities affect the health of individuals. Thus, the moral and professional duties that result are sometimes in conflict.Moreover, the (...) traditional, prosaic clinical encounter is evolving in an environment increasingly shaped by electronic health records, personal health records, pharmacogenomics and vast networks of data collection and storage for public health surveillance, human subjects research, health services evaluation, and comparative effectiveness research. Health information technology is changing everything. It would be perverse otherwise: imagine large amounts of data and information either ignored, missed, or collected and then ignored. (shrink)

Volume 20, Issue 5, June 2020, Page 38-40.

This article traces the rapid progression of policy pertaining to human genome germline modifications using genome editing. It provides an overview of how one fertility physician implemented and advertised experimental techniques as part of his fertility clinic services, examines US law and policy, and assesses the impact of rhetoric influencing global policy and interpretation of the law. This article provides an in-depth examination of the medical rationale driving the acceptance of genome editing human embryos in two contexts: to cure disease (...) and treat infertility. It describes complexities in genomics and outlines risks currently associated with genome editing, asserting the available evidence fails to demonstrate genome editing constitutes a curative therapy. (shrink)

The case of Terri Schiavo, a young woman who spent 15 years in a persistent vegetative state, has emerged as a watershed in debates over end-of-life care. While many observers had thought the right to refuse medical treatment was well established, this case split a family, divided a nation, and counfounded physicians, legislators, and many of the people they treated or represented. In renewing debates over the importance of advance directives, the appropriate role of artificial hydration and nutrition, and the (...) responsibilities of family members, the case also became one of history's most extensively litigated health care disputes. The Case of Terri Schiavo assembles a team of first-hand participants and content experts to provide thoughtful and nuanced analyses. In addition to a comprehensive overview, the book includes contributions by Ms. Schiavo's guardian ad litem, a neurologist and lawyer who participated in the case, and scholars who examine issues related to litigation, faith, gender, and disability. The volume also includes a powerful dissent from the views of many scholars in the bioethics community. The book is intended for students, health care professionals, policy makers, and other in search of carefully reasoned analyses of the case that will shape our view of death and end-of-life medical care for decades. (shrink)

This study draws on Relevance Theory, Conversation Analysis, and Politeness Theory in investigating a full range of discourse functions for hao and dui with reference to recurrent patterns, distributions, and forms of organization in a large corpus of talk. Special emphasis is placed on a comparison of hao and dui in combination with a small subset of discourse particles: in particular hao/hao le/ hao la/hao a/hao ba and dui/dui a/dui le in spoken discourse. We find that both of the markers (...) signal special sequential relatedness in talk and carry information which is relevant in determining the boundaries of conversational exchange. However, in interaction hao is used for expressing acceptance of the other speaker’s move or act, whereas dui conveys acknowledgment of the propositional content of the utterance produced by the other speaker. (shrink)

This paper explains the phenomena that compose the experience of the passage of time and argues that this experience represents the temporal direction of causal processes. The experience of the passage of time comprises several more specific experiences, namely: (1) the experience of continuously advancing to later times; (2) the observation of continuous change, both in the things around us and in ourselves; (3) the feeling of a lack of control over (1) and (2); and (4) the experience of a (...) number of phenomena that we describe as animated, dynamic, or flowing. The experience of passage is a causal process whose function is to promote survival and reproductive success by representing the temporal direction of causal processes (including itself). It does this primarily via the specious present, wherein later content is presented as more vivid than earlier content. The experience of passage is veridical and is compatible with either the B‐theory or the A‐theoretic views of time. (shrink)

Illustrates Plato’s theory of the philosopher-king in the context of medieval and Renaissance Jewish thought.

The most commonly encountered and most serious objection against consequentialist theories of punishment is that they could sometimes endorse punishing innocent people. Two-level consequentialists...

Although at first glance, “facts” are the paradigms of straightforwardness, something about facts seems to invite perpetual controversy and dichotomizing. Innumerable bifurcations on the topic have included "Facts vs. Theories”, “Facts vs. Appearance”, "Facts vs. Values", ... and, popular nowadays, "(Real)Facts vs. Fake Facts". This paper most aligns with the facts vs. theories model, so far as whatever facts are, theories seem to be constructed stories that are necessary for connecting and interpreting the facts. Yet the boundary between the two (...) is fluid and fuzzy: Fact in one context is theory in another, depending on what is being accepted or contested at the time. This paper’s views are compatible with—but neutral on the plausibility of having—an optimism like Peirce’s that scientific inquiry may nonetheless converge towards a consensus. To illustrate the challenges of finding “straightforward” facts, the paper includes a case example, related to research on possible health effects of exposure to electromagnetic-field radiation (EMF). _ The source paper for this 2018 update was originally presented at the University of Waterloo 30th Anniversary Philosophy Conference, 1993. (shrink)

If overstatements were a symptom of the agency conflict, pay-for-performance sensitivities should have increased in response to the additional penalties for misreporting imposed by SOX. Our finding of their decrease is inconsistent with the view that overstatements were an unintended consequence of incentive pay prior to 2002. To corroborate our interpretation, we show that CEO pay-for-performance sensitivities are higher among firms whose shareholders stand to benefit from overstatements; this cross-sectional relationship weakens significantly after SOX; and the within-firm decrease in pay-for-performance (...) sensitivity is most pronounced among firms with high pre-SOX shareholder benefits from overstatements. (shrink)

The ethics of treating the seriously and critically ill have not been static throughout the ages. Twentieth century medicine has inherited from the nineteenth century a science which places an inappropriate weight on diagnosis over prognosis and management, combined with a seventeenth century duty to prolong life. However other earlier ethical traditions, both Hippocratic and Christian, respected both the limitations of medicine and emphasised the importance of prognosis. This paper outlines some of the historical precedents for the treatment of the (...) critically ill, and also how the current paradigm limits clinical practice and causes ethical tensions. An understanding that other paradigms have been ethically acceptable in the past allows wider consideration and acceptance of alternatives for the future. However future alternatives will also have to address the role of technology, given its importance in this area of medicine. (shrink)

This article contributes to existing feminist technoscience analyses by proposing a new tool for examining how norms governing viable and unviable bodies are discursively constructed in an increasingly technologized world. This tool is the result of synthesizing two existing concepts: white noise from the field of media theory/information studies, and the abject from psychosemiotics/gender studies. Synthesizing these two concepts produces an enriched term for detecting interrelations between discursive disturbances and disturbances in bodily norms. In this article, the synthesized concept is (...) used as a tool to analyse material concerning the assignment of International Nonproprietary Names to biotechnological drugs. Biotech offers itself as a prime testing ground for this new tool, replete as it is with bodily anxieties, powerful discourses and innovative technologies. This article compares three versions of an INN guidance document showing how anxieties about bodily norms are reflected in, and managed through, these documents. (shrink)

Throughout history, one focus of society has been expanding and educating its less fortunate or less advanced. This has not change in the twenty-first century. It seems to be a topic in every political election: what are you going to do to help the poor? What are you going to do to help the poor in other countries? The mistreatment of others is all over the media. It fills the home and the head. The squalor of poorer countries is featured (...) on the nightly news. People typically say, send food. Send medicine. One man had a different idea. Send education in the form of inexpensive laptops. (shrink)