Eukaryotic genomes are packaged into nucleosomal chromatin, and genomic activity requires the precise localization of transcription factors, histone modifications and nucleosomes. Classic work described the progressive reassembly and maturation of bulk chromatin behind replication forks. More recent proteomics has detailed the molecular machines that accompany the replicative polymerase to promote rapid histone deposition onto the newly replicated DNA. However, localized chromatin features are transiently obliterated by DNA replication every S phase of the cell cycle. Genomic strategies now observe the rebuilding (...) of locus‐specific chromatin features, and reveal surprising delays in transcription factor binding behind replication forks. This implies that transient chromatin disorganization during replication is a central juncture for targeted transcription factor binding within genomes. We propose that transient occlusion of regulatory elements by disorganized nucleosomes during chromatin maturation enforces specificity of factor binding. (shrink)

Abstract: Perhaps dating back to the fourth century BCE, Shinto traditions in Japan have evolved through the years and have become distinct as Buddhist and Chinese influences have migrated eastward. Kami, supernatural creatures that live in heaven or exist on Earth as sacrosanct forces in nature, are a distinctive aspect of Shinto, which continues to permeate modern Japanese culture. The term "Shinto" refers to the religious ideas and customs that are said to have originated in Japan before the sixth (...) century CE, when Asian religious traditions began to be imported into the country. With a few historical exceptions, the Japanese have avoided attempting to spread Shinto outside of their country because they consider it to be the core of their cultural identity and legacy. Contrary to popular belief, Shinto has had a significant influence on world history. Shinto had a significant impact on how Japan interacted with foreign cultures. Furthermore, it is still a significant religious and cultural institution in modern Japan. Keywords: Shinto, kami, Buddhism, monk, Japan, worship, political dominance, shrine. (shrink)

This article proposes an analysis of changes implemented during Malaysia's Prime Minister Abdullah Ahmad Badawi's administration (20032003), which displayed bias against changes and introduced schemes to justify the systems it upheld. Transmutations wrought during Abdullah's tenure may have been neither substantial nor totalizing, but within the conservative paradigm which had long gripped national politics, Abdullah's deviations were significant nevertheless.

The aim of present paper is to introduce the concept of ‘expressive perception’ in Ernst Cassirer’s philosophical mythology. Having Cited Dorothy Emmet’s methodological objection, the author, by recalling Kantian aspect of Cassirer’s thought and referring to the concept of ‘expressive perception’, would make an attempt to reply on his part: according to Cassirer, this level of perceptive experience is the origin of the mythical form of thinking as a whole and, at the same time, is the original and irreducible altogether. (...) Thus, taking ‘mythical thought’ as an independent form of thinking, beside the ‘critical-empirical’ form of thinking, is, for one thing, completely cogent; for another, due to its dependency upon expressive form of perception, mythical thought would never be quite omitted, rather, keep living latently beneath the skin of mental life. In addition, author explains how much Cassirer owes, regarding to the concept of ‘expressive form of perception’, to Max Scheler. Avoiding to elaborate on Scheler’s detailed argument, Cassirer relies strongly on the consequences Scheler draws from his considerations in his work ‘Wesen und Formen der Sympathie’. Restating Scheler’s argument briefly should help in understanding Cassirer’s idea. (shrink)

At the turn of the millennium, new sensibilities are opening for the human spirit. Dimensions of the mind long forgotten since the beginning of the ...

Religionen sind ästhetisch vermittelt. Nicht nur die religiöse Praxis, sondern der religiöse Habitus überhaupt vollzieht sich in ästhetischen Akten. In diesem Band wird dem komplexen Feld der ästhetischen Inszenierung des Religiösen multidisziplinär Rechnung getragen, und zwar mit besonderem Augenmerk auf filmisch-serielle Narration.

The paper describes the design of an intelligent tutoring system for teaching Introduction to Computer Science-a compulsory curriculum in Al-Azhar University of Gaza to students who attend the university. The basic idea of this system is a systematic introduction into computer science. The system presents topics with examples. The system is dynamically checks student's individual progress. An initial evaluation study was done to investigate the effect of using the intelligent tutoring system on the performance of students enrolled in computer science (...) curriculum at Al-Azhar University, Gaza. The results showed a positive impact on the evaluators. (shrink)

Irfan Ahmad makes the far-reaching argument that potent systems and modes for self-critique as well as critique of others are inherent in Islam--indeed, critique is integral to its fundamental tenets and practices. Challenging common views of Islam as hostile to critical thinking, Ahmad delineates thriving traditions of critique in Islamic culture, focusing in large part on South Asian traditions. Ahmad contemplates and interrogates Greek and Enlightenment notions of reason and critique, and he notes how they are invoked (...) in relation to "others," including Muslims. Drafting an alternative genealogy of critique in Islam, Ahmad reads religious teachings and texts, drawing on sources in Hindi, Urdu, Farsi, and English, and demonstrates how they serve as expressions of critique. Throughout, he depicts Islam as an agent, not an object, of critique. (shrink)

Decolonization and Psychoanalysis challenges traditional psychoanalytic frameworks by revisiting Lacan's conceptualization of the materiality of speech through a decolonial lens. Ahmad Fuad Rahmat explores how Lacan's ideas about the symbolic order and its historical development are intertwined with colonial assumptions, and proposes that rethinking these assumptions can pave the way for a decolonial psychoanalysis. The book explores how Lacan uses Freud's Jewishness as a marginalized perspective that reveals the excluded dimensions of signification within the symbolic order, and examines James (...) Joyce's anti-colonial politics and its significance for Lacan's conception of the sinthome. The critique extends to Slavoj Žižek's Eurocentric readings of Malcolm X as a foil with which colonized speech could be conceived as 'symbolic dispossession.' Finally, it reframes the gap by understanding global capitalism as a mode of exchange to advocate for a decolonial psychoanalysis that focuses on the gaps and non-spaces of transmission as opposed to a like for like export of the clinic from the center to the periphery. Decolonization and Psychoanalysis will be of great interest to psychoanalysts and to academics and scholars of psychoanalytic studies, critical theory and cultural studies. (shrink)

A co-creation values consumers’ input as its primary crust in informing businesses on current consumer needs. More importantly, it would be the next shape in future demands of consumers in business sustainability. This paper addressed this context, narrowing its scope in investigating the voices of stakeholders on what would be the essential aspects of the present and future youth qualities in achieving sustainable well-being in the present trend. The findings would be essentially helpful for the youth and the business world (...) to understand the aspects of good youth development, which would shape the next fabric of consumerism. Self-potential development of the youth is vital in achieving excellent life quality and the youth’s well-being in Malaysia. However, the increase in challenges faced by today’s youth is inconsistent with a decline of the group’s well-being. There are various studies and interventions implemented to overcome the youth situation. However, there is still in need for a model that can guide the holistic development of youth self-potential. The purpose of this study is to build a sustainable and comprehensive model of the self-potential development of the youth, which can be integrated with all of the self-potential indicators of the youth via a co-creation process. This study used the Fuzzy Delphi Method on the proposed elements in the development model and systematically analyzed them using Interpretive Structural Modeling to create the development model. The method capitalized 10 stakeholders from various youth development backgrounds in developing the model. The model consists of 25 sub-indicators that are divided into five indicators. The model findings show that one of the most driving indicators is an entrepreneurial mindset among youth, followed by the other indicators of youth self-potential development. The model also shows that the civic-mindedness indicator is the output of youth self-potential that will surface at an end of the development. The model will guide the authorized body on the priority elements that can systematically and strategically improve youth self-potential to meet future challenges with youth aspirations. (shrink)

This study provides a detailed description of ways in which Muslim astronomers handled the Greek astronomical legacy, reassessed its cultural and philosophical implications in light of their religiously-inspired world view, and proposed to modify it.

In this article, I will offer some remarks on and analysis of the epistemic approach to understanding dialogue and difference of its nature to negotiation. My conceptual deliberations on dialogue have been influenced by two contemporary European philosophers, Hans-Georg Gadamer and Karl Raimund Popper, as well as by the mystical and visionary elaborations of the Persian Islamic thinker, Jalaluddin Rumi of the thirteenth century. I will elaborate on the topics of dialogue and the arts of questioning and listening; dialogue and (...) the issue of language and being; and dialogue and its conduct. I will then address the socio-political conditions necessary for a genuine dialogue; and finally, I will briefly review UNESCO’s raison d'etre and conclude with a discussion of dialogue’s relevance to UNESCO’s mission. (shrink)

The adoption of halal practices in the food and beverage industry is crucial for ensuring compliance with Islamic principles and meeting the growing demand for halal products. This qualitative study explores the perspectives of food and beverage producers and halal authorities on the implementation of halal practices in supply chain management. Focus group discussions were conducted with nine industry participants under the auspices of the Indonesian Institute for the Study of Food, Drugs, and Cosmetics (LPPOM). The discussions aimed to identify (...) behaviors and actions in adopting halal practices based on personal perceptions. The focus group discussions were recorded, transcribed, and analyzed to identify patterns and classify ideas into categories. The findings reveal nine key indicators of halal practice adoption behavior, including purchasing halal raw materials, managing warehouse storage areas, maintaining personal hygiene, managing the cleanliness of facilities and equipment, controlling the sourcing of halal materials, controlling the production process, disseminating halal information, conducting internal audits, and managing financial transactions. The study highlights the importance of these practices in preventing contamination, ensuring strict production processes, promoting effective communication, and maintaining financial transparency. The insights gained from this exploratory research contribute to a deeper understanding of halal practice adoption behavior and support the development of conceptual models for halal supply chain management in the food and beverage industry. (shrink)

What is the function of logic in al-Kindī's corpus? What kind of relation does it have with mathematics? This article tackles these questions by examining al-Kindī's theory of categories as it was presented in his epistle On the Number of Aristotle's Books, from which we can learn about his special attitude towards Aristotle theory of categories and his interpretation, as well. Al-Kindī treats the Categories as a logical book, but in a manner different from that of the classical Aristotelian tradition. (...) He ascribes a special status to the categories Quantity and Quality, whereas the rest of the categories are thought to be no more than different combinations of these two categories with the category Substance. The discussion will pay special attention to the function of the categories of Quantity and Quality as mediators between logic and mathematics. (shrink)

To counter a general belief that all the paradoxes stem from a kind of circularity (or involve some self--reference, or use a diagonal argument) Stephen Yablo designed a paradox in 1993 that seemingly avoided self--reference. We turn Yablo's paradox, the most challenging paradox in the recent years, into a genuine mathematical theorem in Linear Temporal Logic (LTL). Indeed, Yablo's paradox comes in several varieties; and he showed in 2004 that there are other versions that are equally paradoxical. Formalizing these versions (...) of Yablo's paradox, we prove some theorems in LTL. This is the first time that Yablo's paradox(es) become new(ly discovered) theorems in mathematics and logic. (shrink)

Religious pluralism from the perspectives of Islamic epistemology and the practive of Islamic liberalism in Malaysia.

This article discusses continuities and changes of educational institutions during the political transition from the Seljuq dynasty to the Ottoman sultanate. It diachronically examines elements of education which were transformed and adapted into a new political structure under the political regime, the Ottoman. This article will closely look at institutional transformation and educational curricula as to which the changing political regime affected contents and management of Islamic education. This article further argues that the political transformation from the Seljuq to the (...) Ottoman had generated a new educational system in which the Ottoman imposed the attempts to integrate Islam and modern sciences. At managerial level, the transformation has also invited the introduction of science in Islamic educational system. Western educational system reserved as an important reference for this transformation amid the changing regime from the Seljuq to the Ottoman. (shrink)

A part of chapter 1, Book II of the Physics of the Šif¯ ' is dedicated to the aristotelian definition of motion . The developments to which the treatment of this question gives rise are distinctive of the Avicennian style in his Physics . By assuming the notion of double entelechy, Avicenna is following the most classical exegetical tradition. However, by setting a correspondence between the double entelechy and the double notion of motion: 1) motion as an intermediary state, which (...) can be ascribed to a moving object at any instant of its trajectory, and 2) motion as a traversal of a given distance, which cannot be ascribed to the moving object, but at the end-point of its trajectory, Avicenna gives a new content to a lieu commun of the exegetical tradition. (shrink)

The setting of evidential standards is a core practice of scientific assessment for policy. Persuaded by considerations of inductive risk, philosophers generally agree that the justification of evidential standards must appeal to non-epistemic values but debate whether the balance of non-epistemic reasons favours varying evidential standards versus maintaining fixed high evidential standards in assessment, as both sets of standards promote different and important political virtues of advisory institutions. In this paper, I adjudicate the evidential standards debate by developing a novel (...) argument from justice, drawing on the IPCC’s assessment of climate impacts as a case study. I argue that in assessments marked by background evidential inequality, maintaining fixed high evidential standards results in an unequal distribution of ‘epistemic power’ among stakeholders, producing a ‘powerful assessment’ for the data-rich (a high rate of findings) and a ‘weak assessment’ for the data-poor (a low rate of findings). Where such inequalities of epistemic power disadvantage those in data-poor regions with respect to fundamental interests, such as basic human rights, we have decisive reasons of justice to vary evidential standards. (shrink)

The integration of modern Western philosophy with the study of Sufism tradition wasn’t quite familiar. So far, philosophical Sufism is often studied from the perspective of neo-platonic philosophy which is famous for its emanation doctrine. Through this research, the author proposes a new integration by using the philosophical concept of Heidegger’s hermeneutics and Roland Barthes’s semiotics as perspectives in studying the phenomena of the philosophical Sufism tradition. The hermeneutic theory of Martin Heidegger used in this research is existential primordial verstehen (...) and the theory of facticity. Whereas Semiotic theory used in this research is Roland Barthes’s theory of order of signification which is used to analyze Sufi’s connotative interpretation of the Qur’an verse. The method used in this research is analysis descriptive by a combined table of hermeneutic and semiotic theories through library research on several primary sources concerning Sufi’s interpretation such as Miftahus Sufi, al-Luma‘, Shaṭaḥāt al-Sūfiyyah, etc. As a result, in the perspective of Sufism Primordial Verstehen, the doctrines of Sufism such as ittiḥād, ḥulūl, and waḥdah al-wujūd could be understood as existential primordial understanding in contemplating Sufi’s existence in the world and his arrival at the understanding of Allah as the only existing Being. (shrink)

Despite having unwelcome effects on interpersonal relationships, disagreements constitute the mainstream of talk in dissertation defense sessions. This paper reports on variations in the design of disagreement turns in 20 Iranian defense sessions in L2 English. Drawing on and modifying Locher’s classification of disagreement strategies, turns were classified into two main categories of “mitigated” and “unmitigated”. Then, for each category, linguistic and paralinguistic devices, which were used in framing disagreements, were identified. The data features almost an equal number of mitigated (...) and unmitigated disagreements. “But with hedged contradictory remarks”, and “hedges” were the most frequent mitigating strategies, whereas “Direct opposite views” and “but with contradictory remarks” were the most frequent strategies in unmitigated and aggravated disagreements. Finally, the implications of the results for research on face and institutional talk are discussed. (shrink)

After some conceptual elaboration on the topic of the Dialogue among Civilizations, this article will give some examples of UNESCO’s contribution in this domain. DAC is intrinsically bound to the questions of identity and otherness through the role culture and civilization play in composing our identity. We forge our own identity through our culture; those who share this identity are insiders, and those who do not are outsiders. Some understandings of identity conclude in a lack of appreciation for the Others’ (...) identity, which is necessary to being a genuine partner in dialogue. At one extreme personal identity is not conceived as being subject to any changes during an individual’s lifetime; while at the other extreme, post-modernism perceives a person or a social group simply as a node in a network of relations. These definitions both suffer from the lack of a historical dimension and are based on a unitary conception of identity. The solution, as the reality of history also demonstrates, comes with a pluralistic view of identity, which not only solves some theoretical issues but also forms the only framework within which the possibility of dialogue can be assured. The wonderful consequence will then be that if absolute identity does not exist, neither can absolute otherness. We should then search for the shared roots between different cultures. It was a common scientific and philosophical culture, for example, that united Avicenna in Iran with St. Thomas Aquinas in the West; a culture going back to the Greek and Hellenistic thinkers. Globality should be understood as a visionary search for the discovery of the common roots of different cultures, rather than the dominance of any one particular culture or value system. The ethnocentric concept of culture and history can then be overcome. A genuine dialogue comes with the soul’s particular willingness to “convert” itself, to expose and risk one’s own ideas and positions. It brings us the possibility of overcoming trans-cultural dissensus on whether a particular practice violates one or another human right. And as we know from Averroes, the human soul comes from a unified universal soul. Finally, there is an inter-conceptual linkage among cultural diversity, tangible and intangible cultural heritage, sustainable development, human rights and cultural rights. UNESCO, by preserving and protecting cultural heritage, safeguarding cultural diversity, and promoting dialogue among cultures and civilizations, is contributing to its axiomatic constitutional goals, namely the construction of the defenses of peace in the minds of people through moral and intellectual solidarity. (shrink)

Inspired by Said’s concept of exile, Camus’ 1947 novel The Plague, and testimonies from our students, this paper explores the striking similarities between experiences of exile and the COVID-19 pandemic. Both exile and the pandemic are seen as intrusive forces causing rupture and discontinuity in one’s life at the physical, psychological and socio-cultural levels. This paper demonstrates that for many Palestinians – including us and our students – the pandemic manifests what Freud termed ‘repetition compulsion’. That is, many of our (...) students interpret the detrimental and precarious impact of the pandemic as a complex form of exile, a nuanced understanding that blends a historical, communal memory of displacement with a present, universal crisis. This paper further explains that the themes of exile and displacement in Camus’ The Plague provide us and our students with a focal point to examine the striking, albeit anachronistic, similarities between the pandemic caused by Israeli occupation and the COVID-19 virus. This uncanny relationship between the pandemic and exile is further substantiated by the fact that the pandemic has provided cover, or at least distraction, for the escalation of oppressive political actions, thus deepening the entrenchment of a physical and psychological ‘exile’ for Palestinians. (shrink)

Les etudes sur Averroes (1126-1198) ont porte jusqu'ici, pour l'essentiel, soit sur un aspect de sa psychologie philosophique, soit sur sa doctrine politique. Le premier type d'etudes se situe dans le prolongement de la reception medievale latine d'Averroes, caracterisee par les controverses suscitees par sa noetique. Le second reflete un courant de la recherche qui a domine l'histoire recente de la philosophie arabe et qui a mis l'accent sur l'etude des rapports entre religion et philosophie. Sans negliger ces deux orientations, (...) ce volume, qui rassemble des contributions de specialistes mondialement reconnus d'Averroes, cherche ... donner une vision plus globale de cet auteur en etudiant toutes les facettes de son oeuvre. Il vise aussi ... reequilibrer l'approche de sa pensee, en insistant sur des aspects peu etudies de celle-ci et qui relevent de la logique, de la philosophie naturelle, de la medecine ou de la methodologie juridique. Les etudes ici rassemblees contribuent ainsi ... jeter une lumiere neuve sur cette figure marquante de la pensee universelle. Les etudes sur Averroes (1126-1198) ont porte jusqu'ici, pour l'essentiel, soit sur un aspect de sa psychologie philosophique, soit sur sa doctrine politique. Le premier type d'etudes se situe dans le prolongement de la reception medievale latine d'Averroes, caracterisee par les controverses suscitees par sa noetique. Le second reflete un courant de la recherche qui a domine l'histoire recente de la philosophie arabe et qui a mis l'accent sur l'etude des rapports entre religion et philosophie. Sans negliger ces deux orientations, ce volume, qui rassemble des contributions de specialistes mondialement reconnus d'Averroes, cherche ... donner une vision plus globale de cet auteur en etudiant toutes les facettes de son oeuvre. Il vise aussi ... reequilibrer l'approche de sa pensee, en insistant sur des aspects peu etudies de celle-ci et qui relevent de la logique, de la philosophie naturelle, de la medecine ou de la methodologie juridique. Les etudes ici rassemblees contribuent ainsi ... jeter une lumiere neuve sur cette figure marquante de la pensee universelle. (shrink)

Çalışma İslam hukukunun çevre ve toplumların sahip olduğu tabi kay-nakları koruma konusunda öngördüğü düzenlemelerin fıkhi ve iktisadi boyutunu açıklamayı hedef almaktadır. Araştırmamız esnasında inceledeğimiz temel dini metinler ve bunlar arasında yaptığımız karşılaştırmalar bize İslam hukukunun çevreyi ve tabi kaynakları koruma ve geliştirmeye yönelik düzenlemelere sahip olduğunu ortaya koymaktadır. Bu çalışma gösteriyor ki İslam'ın ilkeleri ve şeriat çevreye önem vermeye, özen göstermeye, tüketimde orta yolu gözetmeye ve israf yapmamaya davet etmektedir. Aynı şekilde kalkınmaya ve yeryüzünü imar etmeye ve ekonomik yararlarını gerçekleştirecek (...) şekilde ümmetin kaynaklarını korumaya da davet etmektedir. (shrink)

The present volume is a collection of original articles of high quality on the Philosophy of Science by philosophers and scientists of international repute. As the title of the book suggests, it looks at the various points of view of leading practitioners, as well as philosophers on the nature and structure of our knowledge of the physical world. The present work brings forth the fundamental ideas of Bacon, Galileo, Newton, Descartes, Popper, Einstein, Thomas Kuhn and several other leading scientists and (...) philosophers. (shrink)

Two sample populations, one refugee and one resident, were studied. The frequencies of consanguineous marriages came out to be 49·8% and 55·4%, respectively, for the refugees and the residents. Caste endogamy was dominant both in the residents and the refugees. The mean coefficient of inbreeding was calculated to be 0·0303 for the refugee population and 0·0332 for the resident population samples. First cousin marriage was the dominant type of marriage in both samples; fathers daughter (FBD) marriage was more frequent among (...) the refugees while mothers daughter (MBD) marriage was more frequent among the residents. Education has no decreasing effect on the incidence of consanguineous marriages. A significant difference in the pattern of marriages in the refugees is observed after the Saur Revolution of 1979. (shrink)