Background: Parkinson’s disease is a neurodegenerative disease in which the progressive loss of dopaminergic neurons leads to initially sporadic and eventually widespread damage of the nervous system resulting in significant musculoskeletal and cognitive deterioration. Loss of motor function alongside increasing cognitive impairment is part of the natural disease progression. Gait is often considered an automatic activity; however, walking is the result of a delicate balance of multiple systems which maintain the body’s center of mass over an ever-changing base of support. (...) It is a complex motor behavior that requires components of attention and memory to prevent falls and injury. In addition, evidence points to the critical role of salient visual information to gait adaptability. There is a growing understanding that treatment for PD needs to address movement as it occurs naturally and walking needs to be practiced in more complex environments than traditional therapy has provided.MethodsIn this single-blinded randomized-controlled pilot study, an immersive treadmill training was piloted to determine feasibility and preliminary efficacy on gait and cognition in people with PD. Eighteen participants with Hoehn and Yahr stages I-III PD were randomized to either an intervention or a waitlist control group. Following baseline data collection, the intervention group trained for 30 min, three times/week for 4 weeks on a split belt treadmill combined with a first-person immersive video game targeting visuospatial skills and working memory. Assessment was repeated after 4 weeks of training for the experimental group and 1-month after baseline for the control group. Primary motor outcomes were captured with the APDM Opal sensors during 6 MWT, TUG, and TUG Cognitive. Secondary outcomes of cognition were measured with the Montreal Cognitive Assessment, Verbal Fluency and the Symbol Digit Modality Test. Within subject differences were calculated using the Wilcoxon Signed Ranked Test and between subject comparisons were analyzed using the Mann Whitney U-test.ResultsThis novel treadmill training program was well-tolerated with all participants in the intervention group completing 4 weeks of training three times a week without any adverse effects. After immersive cognitive motor training, the experimental group made clinically relevant improvements in gait speed and walking distance during the 6 MWT while members of the control group showed no change or decreased gait speed and walking distance over the 1-month trial. In addition, the experimental group demonstrated significant improvement for the TUG Cognitive and those changes were greater than the control group. The experimental group also improved scores on MoCA and SDMT cognitive outcome measures while the control group did not.ConclusionThe use of immersive gaming technology to engage specific areas of cognition related to gait is feasible in PD. The treadmill training program paired with a customized interactive video game improved walking velocity in addition to non-significant but consistent improvements in other gait measures and cognitive performance in participants with early to mid-stage PD. (shrink)

Transcranial magnetic stimulation (TMS) of the visual cortex can induce phosphenes as can non-diagnostic ultrasound, the latter while participants have closed their eyes during Stimulation. Here we sought to study potential alteration of a visual target (a white crosshair) due to application of diagnostic ultrasound to the visual cortex. We applied a randomized series of actual or sham diagnostic ultrasound to the visual cortex of healthy participants while they stared at a visual target, with the ultrasound device placed where TMS (...) elicited phosphenes. These participants observed percepts 7 out of 10 times, consisting of extra or extensions of lines relative to the original crosshair, and additional colors. Observation of a percept occurred an average of 53.7 +/- 2.6% of the time over the course of the experiment for these participants. In contrast, 7 out of 10 participants exposed to sham-only diagnostic ultrasound observed comparable percepts an average of 36.3 +/ 1.9% of the time, a statistically significant difference (p < 0.00001). Moreover, on average, participants exposed to a combination of sham and actual ultrasound reported a net increase of 47.9 percentage points in the likelihood that they would report a visual effect by the end of the experiment. Our experiment demonstrated that a random combination of sham-only and actual diagnostic ultrasound applied to the visual cortex of participants increased the likelihood that they would observe visual effects, but not the type of effects, with that likelihood increasing over the course of the experiment. From this we conclude that repeated exposures by diagnostic ultrasound made the visual cortex more responsive to stimulation of their visual cortex by the visual target. These observations, consistent with other’s observation of effects of diagnostic ultrasound stimulation of human motor cortex and amygdala, as well as the FDA approved nature of diagnostic ultrasound, may lead to increased study of diagnostic ultrasound applied to human brain. (shrink)

Seth Vannatta argues that there can be a fruitful synthesis of pragmatism and classical conservatism. In doing this, he focuses the methodological commitments of pragmatism and conservatism. However, I will demonstrate with a reading of Dewey’s Liberalism and Social Action that other commitments might prevent this synthesis—at least a synthesis between the thought of John Dewey and Edmund Burke. My conclusion is that pragmatism and conservativism might travel parallel to one another but that we have good reasons for keeping (...) some separation between the theories based upon their fundamental commitments. Deweyan pragmatism remains tied to democracy; conservatism remains tied to history. (shrink)

Despite its small stature, "if" occupies a central place both in everyday language and the philosophical lexicon. In allowing us to talk about hypothetical situations, "if" raises a host of thorny philosophical puzzles about language and logic. Addressing them requires tools from linguistics, logic, probability theory, and metaphysics. Justin Khoo uses these tools to navigate a maze of interconnected issues about conditionals, some of which include: the nature of linguistic communication, the relationship between logical and natural languages, and the (...) relationship between different kinds of modality. According to Khoo's theory, conditionals form a unified class of expressions which share a common semantic core that encodes inferential dispositions. Thus, rather than represent the world, conditionals are devices used to communicate how we are disposed to infer. Khoo shows that this theory can be extended to predict the probabilities of conditionals, as well as how different kinds of conditionals differ both semantically and pragmatically. Khoo's book will make for a significant contribution to the literature on conditionals and should be of interest to philosophers, linguists, and computer scientists. (shrink)

I develop a reduction of grounding to essence. My approach is to think about the relation between grounding and essence on the model of a certain conceptof existential dependence. I extend this concept of existential dependence in a coupleof ways and argue that these extensions provide a reduction of grounding to essenceif we use sorted variables that range over facts and take it that for a fact to obtain is forit to exist. I then use the account to resolve various (...) issues surrounding the concept of grounding and its connection with essence; apply the account to paradigm cases andto the impure logic of grounding; and respond to objections. (shrink)

Functionalist theories have been proposed for just about everything: mental states, dispositions, moral properties, truth, causation, and much else. The time has come for a functionalist theory of nothing. Or, more accurately, a role functionalist theory of those absences that are causes and effects.

This paper focuses on the concept of collective essence: that some truths are essential to many items taken together. For example, that it is essential to conjunction and negation that they are truth-functionally complete. The concept of collective essence is one of the main innovations of recent work on the theory of essence. In a sense, this innovation is natural, since we make all sorts of plural predications. It stands to reason that there should be a distinction between essential and (...) accidental plural predications if there is a distinction among singular predications. In this paper I defend the view that the concept of collective essence is governed by the principle of Monotonicity: that something is essential to some items only if it is essential to any items to which they belong. (shrink)

Kant calls his Transcendental Deduction "the most difficult thing that could ever be undertaken on behalf of metaphysics" (4:260). Readers have found it not just difficult but downright impossible. I will address two long-standing problems. First, Kant seems to contradict his conclusion at the outset of his proof. He does so in both the 1781 and 1787 editions of his Critique of Pure Reason. Second, Kant seems to argue for his single conclusion twice over in his Critique's 1787 edition. I (...) will propose novel solutions by considering why Kant's Deduction is more difficult than his Transcendental Aesthetic, on one hand, and his 1770 Inaugural Dissertation, on the other. My broader aim is to oppose a subjectivist interpretation of Kant's Deduction with an original interpretation. On the subjectivist interpretation, Kant holds that the categories apply to appearances because appearances necessarily conform to our subjective forms of the understanding. I will argue to the contrary in addressing the first problem. On my interpretation, the reason that the categories apply to appearances is not just because of what our subjective forms of the understanding are. It is because of what objects are as appearances. What are objects as appearances, for Kant? In addressing the second problem, I will argue that they are objects of our possible intuitions and judgments. (shrink)

What is it for something to be essential to an item? For some time, it was standard to think that the concept of necessity alone can provide an answer: for something to be essential to an item is for it to be strictly implied by the existence of that item. We now tend to think that this view fails because its analysans is insufficient for its analysandum. In response, some argue that we can supplement the analysis in terms of necessity (...) with a further condition. In this paper I argue that this view is untenable in its current form. I then provide a glimmer of hope to those who think that essence is at least partially analyzable in terms of necessity. (shrink)

ABSTRACTIn this paper, I develop a truthmaker semantics for essence and use the semantics to investigate the explanatory role of essence.

Recent work on essence describes essence as assimilated to definition. It also posits a plurality of kinds of essence.Howdoes assimilation relate to pluralism? According to one view, a kind of essence is adequate only if it is definitional: something is essential to an item, in the relevant sense, only if it is part of what it is to be that item. In this paper, I argue that assimilation and pluralism are in tension with respect to consequentialist essence. This is problematic (...) given that, as a methodological prescription, some philosophers advise us to work with consequentialist essence. In this paper, I develop a theory of constitutive essence and use it to resolve the problem by defining an adequate notion of consequentialist essence that preserves the methodological prescription. (shrink)

This article critically examines the competitive, adversarial nature of the Western neoliberal style of democracy. Specifically, this article focuses on Amartya Sen’s notion of a “universal democracy” as a means of addressing socio-economic inequalities through Sen’s capability approach. Sen’s capability theory has become an acclaimed and widely used theory to evaluate and understand development and inequalities. However, we employ a distinctive critique by engaging Amartya Sen through Herbert Marcuse’s analysis of one dimensionality and the adversarial nature of Western democracy. We (...) further highlight how contemporary neoliberal society employ a particular, adversarial form of public participation. Through this, we underline the various neoliberal problemata, such as Western idealism, political passivity, and a “flattening of choice,” within contemporary democracies and locate how their competitive, winner-take-all nature has become essential to contemporary, Western democratic models. Consequently, we argue that democracy, as a functional concept and form of public engagement, should be fundamentally re-examined in order to address inequalities. (shrink)

Some parents take advantage of legal exemptions for the measles-mumps-rubella vaccine. While there are a variety of reasons parents do so—including having children with medical conditions that make vaccination medically unsafe—some parents appear to be driven, at least in part, by beliefs that vaccines cause a variety of diseases or conditions, such as autism. Those who delay or refuse the MMR vaccine because of false beliefs about its side effects elicit a strikingly strong response from many who endorse MMR vaccine (...) mandates. Accusations of moral wrongdoing, expressions of anger, indignation, resentment, or disgust frequently appear in social... (shrink)

Liang Tao and Kuang Zhao, trans. Confucian rights can be characterized as a kind of “fallback apparatus,” necessary only when preferred mechanisms—for example, familial and neighborly care or traditional courtesies—would otherwise fail to protect basic human interests. In this paper, I argue that the very existence of such rights is contingent on their ability to function as remedies for dysfunctional social relationships or failures to develop the virtues that sustain harmonious Confucian relationships. Moreover, these remedies are not, strictly speaking, rights-based, (...) for having a right consists in having the power to claim one's rights for oneself, which the classical Confucians would curtail. I conclude by noting how we might revise standard assumptions about the practice of “claiming one's rights” to make it more compatible with core Confucian principles. 梁涛 匡钊译 儒家权利可称为是一种“备用机制”（fallback apparatus），诉诸权利仅当其他首选机制，如家族与邻里的关怀或对传统礼俗的依赖等，不能有效维护人们的基本利益时才是必要的。儒家权利的存在取决于其补救功能，其需要补救的是儒家谐社会关系及相应美德中 出现的危机、过失。但儒家的补救并不完全是基于权利之上的，古典儒家不认为人民可以代表自己提出主张，也不认为民众可以直接推翻昏庸的暴君，有抵抗权的主要是汤、武等第一级的贵族。对于儒家国家来讲，从制度上认可 人民的权利主张可能是获得社会和谐最有效的手段。. (shrink)

How do newborns learn to recognize objects? According to temporal learning models in computational neuroscience, the brain constructs object representations by extracting smoothly changing features from the environment. To date, however, it is unknown whether newborns depend on smoothly changing features to build invariant object representations. Here, we used an automated controlled-rearing method to examine whether visual experience with smoothly changing features facilitates the development of view-invariant object recognition in a newborn animal model—the domestic chick. When newborn chicks were reared (...) with a virtual object that moved smoothly over time, the chicks created view-invariant representations that were selective for object identity and tolerant to viewpoint changes. Conversely, when newborn chicks were reared with a temporally non-smooth object, the chicks developed less selectivity for identity features and less tolerance to viewpoint changes. These results provide evidence for a “smoothness constraint” on the development of invariant object recognition and indicate that newborns leverage the temporal smoothness of natural visual environments to build abstract mental models of objects. (shrink)

I argue that dependence is neither necessary nor sufficient for relative fundamentality. I then introduce the notion of 'likeness in nature' and provide an account of relative fundamentality in terms of it and the notion of dependence. Finally, I discuss some puzzles that arise in Aristotle's Categories, to which the theory developed is applied.

In contrast to scholars and signers in the nineteenth century, William Stokoe conceived of American Sign Language (ASL) as a unique linguistic tradition with roots in nineteenth-centurylangue des signes française, a conception that is apparent in his earliest scholarship on ASL. Stokoe thus contributed to the theoretical foundations upon which the field of sign language historical linguistics would later develop. This review focuses on the development of sign language historical linguistics since Stokoe, including the field's significant progress and the theoretical (...) and methodological problems that it still faces. The review examines the field's development through the lens of two related problems pertaining to how we understand sign language relationships and to our understanding of cognacy, as the term pertains to signs. It is suggested that the theoretical notions underlying these terms do not straightforwardly map onto the historical development of many sign languages. Recent approaches in sign language historical linguistics are highlighted and future directions for research are suggested to address the problems discussed in this review. (shrink)

Virtually all Americans are part of the health care system. They may be patients, health professionals, employers providing benefits, insurers, medical manufacturers, regulators, innovators, or investors. Each has a stake in this burgeoning sector of the United States economy, and each may be critically affected, in multiple and diverse ways, by changes to the system under health reform. As health care expenditures continue to rise, it is increasingly important to understand where these expenditures go and the factors that drive these (...) cost increases. This article examines health care expenditure patterns, considering both the “usual suspects” that frequently are cited as spending drivers, as well as certain significant dynamics that may be the main contributors to rising costs. We conclude that in order to successfully contain costs, health reform will need to address these underlying factors. (shrink)

One can view the recent science fiction films Gravity, Interstellar, and The Martian as a three-part dialogue concerning the existential relationship between humanity, technology, and the science employed to create said technologies. Pitched into the deep of space, each film’s protagonist must seek to find technological answers to save their own existence. Each film’s exploration of these themes essentially questions the importance of technology as a product of scientific-calculative thinking and the validity of this thinking as the primary mode of (...) understanding the world. In this article, I explore the existential dialogue crafted between these films through Walter Benjamin and Martin Heidegger. Through Benjamin, we will see how the medium of film is completely dependent upon technology to present its art and how this transforms the stories it tells, while also transforming the audience and the audience’s reality. Consequently, understanding the popular reception of these films becomes just as important as the films themselves for our present study. Through Heidegger, we will see how technology provides a space where we can find a truth about ourselves and our reality. However, modern technology’s increasing scientific complexity, created by scientists who in turn employ modern technology to further science, also conceals just as much as it reveals. These films provide us with an opportunity to explore a truth about our dependence upon technology even though, as technologically dependent works of art, they may also conceal how dependent upon science we have become when constructing our reality. (shrink)

When it comes to social criticism of the economy, Critical Theory has thus far failed to discover specific immanent norms in that sphere of activity. In response, we propose that what is needed is to double down on the idealism of Critical Theory by taking seriously the sophisticated structure of agency developed in Hegel’s own account of freedom as self-determination. When we do so, we will see that the anti-metaphysical gestures of recent Critical Theory work in opposition to its attempts (...) to develop immanent critique. In this paper we first briefly reconsider Axel Honneth’s project as it concerns economic institutions and then respond by returning to the problem of freedom and articulating a view according to which the problem of individual self-determination and the problem of social production are the same problem seen from different angles. Then we present briefly Hegel’s own social theory from this perspective before moving on to trace the outlines of such a critical theory of contemporary capitalism. (shrink)

Whereas several zoological Aristotelian works have been preserved, Aristotle is reported to have written only one short botanical treatise. Such reports seem to conflict with his self-described ambition to study plants as well as animals. Even though this treatise is now lost, the available evidence suggests that Aristotle had valid reasons to find the subject-matter of plants much less interesting, as their activities amount to a subset of what animals do. When studying attributes common to both plants and animals in (...) the transmitted corpus, Aristotle systematically focuses on the case of the most complex animals and, once an explanatory model has been found, proceeds to apply it to the remaining cases with less details. I argue that this procedure, although it runs counters to the intuition that one ought to start with the most simple case, corresponds to a general scientific method. Consequently, most of Aristotle’s botany is found to be already encapsulated in the main results of his study of animals. (shrink)

I argue that Aristotle’s concept of φάντασμα should neither be equated with the notion of “mental image” nor understood as referring primarily to physiological processes. What Aristotle means by φάντασμα should be understood in the light of a pre-philosophical linguistic background in which the term refers to apparitions of objects that are suspected of not being real, such as ghosts. A φάντασμα in Aristotle is a content of which one is aware by a process which, although quasi-perceptual in nature, is (...) known by the subject or by a third party to differ from perception. (shrink)

In the United States, only 6% of the 1.5 million faculty in degree-granting postsecondary institutions is Black. Research shows that, while many institutions tout the idea of diversity recruitment, not much progress has been made to diversify faculty ranks, especially at research-intensive institutions. We're Not Ok shares the experiences of Black faculty to take the reader on a journey, from the obstacles of landing a full-time faculty position through the unique struggles of being a Black educator at a predominantly white (...) institution, along with how these deterrents impact inclusion, retention, and mental health. The book provides practical strategies and recommendations for graduate students, faculty, staff, and administrators, along with changemakers, to make strides in diversity, equity, and inclusion. More than a presentation of statistics and anecdotes, it is the start of a dialogue with the intent of ushering actual change that can benefit Black faculty, their students, and their institutions. (shrink)

This is a unique collection presenting work by Alain Badiou and commentaries on his philosophical theories. It includes three lectures by Badiou, on contemporary politics, the infinite, cinema and theatre and two extensive interviews with Badiou – one concerning the state of the contemporary situation and one wide ranging interview on all facets of his work and engagements. It also includes six interventions on aspects of Badiou's work by established scholars in the field, addressing his concept of history, Lacan, Cinema, (...) poetry, and feminism; and four original essays by young and established scholars in Australia and New Zealand addressing the key concerns of Badiou's 2015 visit to the Antipodal region and the work he presented there. With new material by Badiou previously unpublished in English this volume is a valuable overview of his recent thinking. Critical responses by distinguished and gifted Badiou scholars writing outside of the European context make this text essential reading for anyone interested in the development and contemporary reception of Badiou's thought. (shrink)

Beginning in the late 1990s we became convinced that our undergraduate psychology students needed classroom experiences that set the conditions for them to become more engaged with beauty. We recognized the intrinsic importance of beauty to human psychological development, beyond any utilitarian concerns.1 But we also believed that there were important psychological benefits to be gained by becoming increasingly engaged with beauty. In this paper we briefly describe some of those benefits that have been documented in the psychological research literature (...) in the last decade. This paper primarily outlines a curricular recipe for infusing beauty into an Introduction to Psychology course at the undergraduate .. (shrink)

Tsenay Serequeberhan’s hermeneutics has been crucial to the development of African philosophy. Initially employed as a pathway through the ethno- and professional philosophical debates, scholars have engaged how Serequeberhan’s hermeneutics grapples with one’s own place within a socio-historical world in service of liberation/self-determination. However, this scholarship mainly has focused on his adaptation of Gadamer’s ‘effective-historical consciousness’ for his own concept of heritage. This consequently leaves his concept of a ‘lived existence’ – which is equally crucial – under-examined. This paper probes (...) what a ‘lived existence’ entails and its essentiality when explicating how one even begins to authentically think, which is the groundwork to Serequeberhan’s hermeneutics. This deepens why his concept of heritage matters as a starting point for self-determination. Addressing this lacuna, this article asks, where does philosophy begin and where should it go, particularly when rationality has been historically denied? Serequeberhan’s point of departure to answer this question proposes Heidegger’s concept of thinking itself to arrive at a notion of existence; contrariwise to most African scholars who employ a Sartrean existentialism via Frantz Fanon. As such, this paper gives an in-depth exploration of Serequeberhan’s initial reading of Heidegger, and then unfolds how he appropriates Heidegger to craft his notion of ‘lived existence’. The upshot this is twofold: First, a broader understanding of Serequeberhan’s project, its non-existentialist view of existence; Second, it describes how he specifically tailors his ‘lived existence’ to undergird his hermeneutical approach to heritage as a prescriptive, activist project which dynamically addresses the postcolonial situation. (shrink)

Professor Schellenberg thinks that recent progress in our moral thinking about what counts as a good person and what counts as morally permissible action strengthen the case for atheism. Moral evolution ought to lead to religious evolution. We don’t think the maneuver works. Despite being a clear and accessible piece of philosophy that makes some important contributions to the literature, the central move of the book falls short. In that sense, Progressive Atheism makes little progress. Our review offers a synopsis (...) and an appraisal of the project. (shrink)

Aristote mentionne à plusieurs reprises au cours de sa Métaphysique une doctrine platonicienne des grandeurs, qui s’inscrit dans la continuité directe de la célèbre instauration des nombres idéaux. Les interprétations les plus couramment retenues, celles de Léon Robin et de W. D. Ross, y voient l’avènement parallèle de « grandeurs idéales », lesquelles seraient à la géométrie ce que les nombres idéaux sont à l’arithmétique. Or Platon, loin de vouloir idéaliser le domaine des grandeurs au même titre que celui des (...) nombres, soutient régulièrement la primauté essentielle de l’arithmétique par rapport à la géométrie, thèse dont l’importance se trouve confirmée par l’analyse des polémiques au sein de l’Académie qu’Aristote rapporte et auxquelles il lui arrive de prendre part. On se propose donc d’esquisser les grandes lignes d’une interprétation du statut des grandeurs en tant qu’entités « après les nombres » au sein de l’ontologie du dernier platonisme, en se fondant sur les renouvellements que la considération de l’histoire des mathématiques a pu apporter à la compréhension des dialogues de Platon. (shrink)

Charting significant growth in science production over the 20th century in four European Union member states, this neo-institutional analysis describes the development and current state of universities and research institutes that bolster Europe’s position as a key region in global science. On-going internationalization and Europeanization of higher education and science has been accompanied by increasing competition as well as collaboration. Despite the policy goals to foster innovation and further expand research capacity, in cross-national and historical comparison neither the level of (...) R&D investments nor country size accounts completely for the differential growth of scientific productivity. Based on a comprehensive historical database from 1900 to 2010, this analysis uncovers both stable and dynamic patterns of production and productivity in Germany, France, Belgium, and Luxembourg. Measured in peer-reviewed research articles collected in Thomson Reuters’ Science Citation Index Expanded, which includes journals in the fields of Science, Technology, Engineering, Mathematics, and Health, we show the varying contributions of different organizational forms, especially research universities and research institutes. Comparing the institutionalization pathways that created the conditions necessary for continuous and strong growth in scientific productivity in the European center of global science emphasizes that the research university is the key organizational form across countries. (shrink)

Contact Info: Paul Pietroski Department of Linguistics University of Maryland Marie Mount Hall College Park, MD 20742 USA Email: pietro@umd.edu Phone: +1 301-395-1747..

Political solutions to problems like global warming and social justice are often stymied by an inability to productively communicate in everyday conversations. Motivated by these communication problems, the paper considers the role of the virtuous listener in conversations. Rather than the scripted exchanges of information between individuals, we focus on lively, intra-active conversations that are mediating events. In such conversations, the listener plays a participatory role by contributing to the content and form of the conversation. Unlike Miranda Fricker’s negative virtue (...) of testimonial justice, which neutralizes the listener’s identity-prejudices in their credibility judgments of the speaker’s testimony, we consider the positive virtues of a good listener. These positive virtues enable listeners to productively contribute to the conversation by helping create the fertile epistemic space of a non-adversarial, caring relationship that facilitates critical and creative thinking. (shrink)