In fields where science and technology overlap, so do different function-ascriptions. The entities of Synthetic Biology research are a case in point, where organisms with biological functionality are altered to perform technical functions. A function theory for SynBiofacts has to address artifactual as well as biological functions of one and the same entity. Further demands on a function theory for Synthetic Biology emerge from methods of SynBiofact creation called kludging and the use-scenarios of SynBiofacts in proof-of-concept research and BioArt. After (...) discussing intentional accounts of technical functions, etiological function theory, contextual causation and contextual selection, a pluralist and weakly normative account of function will be outlined, that, or so it will be argued, can indeed cover all function ascriptions in Synthetic Biology. Lastly, some of the advantages and disadvantages of taking this stance will be outlined. (shrink)

In this editorial introduction, we set out the contexts, aims and contents of this special issue on Schelling’s influence on later religious and theological thought, as well as the rationale behind its genesis.

Psychology and philosophy have long reflected on the role of perspective in vision. Since the dawn of modern vision science—roughly, since Helmholtz in the late 1800s—scientific explanations in vision have focused on understanding the computations that transform the sensed retinal image into percepts of the three-dimensional environment. The standard view in the science is that distal properties—viewpoint-independent properties of the environment (object shape) and viewpoint-dependent relational properties (3D orientation relative to the viewer)–are perceptually represented and that properties of the proximal (...) stimulus (in vision, the retinal image) are not. This view is woven into the nature of scientific explanation in perceptual psychology, and has guided impressive advances over the past 150 years. A recently published article suggests that in shape-perception, the standard view must be revised. It argues, on the basis of new empirical data, that a new entity—perspectival shape—should be introduced into scientific explanations of shape perception. Specifically, the article’s centrally advertised claim is that, in addition to distal shape, perspectival shape is perceived. We argue that this claim rests on a series of mistakes. Problems in experimental design entail that the article provides no empirical support for any claims regarding either perspective or the perception of shape. There are further problems in scientific reasoning and conceptual development. Detailing these criticisms and explaining how science treats these issues is meant to clarify method and theory, and to improve exchanges between the science and philosophy of perception. (shrink)

In this article, Gregory of Nyssa is presented as a trinitarian thinker. It is argued that, in order to appreciate the relevance of triadic structures for his thought, one must take into consideration that the central place the Trinity held in his thought was the result of his involvement in the final phase of the so‑called trinitarian controversy of the fourth century. The article therefore begins with a brief account of the theoretical problems that arose within the later stages of (...) this debate. Particular attention is paid in this connection to the positions of Athanasius and his moderate opponents. In a second step, Basil of Caesarea, Gregory’s older brother, is introduced as a radically innovative voice in the debate. While previous thinkers were agreed on the derivative character of the divinity as passed on from the Father to the other members of the Trinity, Basil insisted on their ontological coordination with the help of terminology taken from Aristotle’s Categories. Gregory’s trinitarian system, which is presented in the remainder of the essay, builds on Basil’s foundations. Through an examination of key texts it is shown, however, that he added a greater concern for the common or shared ousia or physis by means of which divine unity was guaranteed. In this connection, Gregory developed a realistic theory of the universal which he also applied in other parts of his thought, notably his doctrine of creation. The article concludes with the observation that Gregory’s interest in trinitarian structures was different from that of Augustine in that the fundamental problem was the relationship of unity and difference, whereas the number ‘three’ did not play a recognisable role in the Cappadocian’s speculations. (shrink)

The article starts by observing a parallel between the identification of Christ's humanity and universal human nature, for which Harnack repudiates some church fathers, and David Strauss' claim, in his Life of Jesus, that the subject of the Incarnation must be all humanity. It is argued that this oppositional stance is indicative of fundamental philosophical and theological differences between the Tübingen School and the Ritschl School. Those differences, however, are then explained as emerging from what is ultimately a common project (...) of a radical form of historical theology. This project, it is argued, Ritschl took over from Baur while correcting it in crucial ways. Taken together, the two central theological schools of the 19th century thus illustrate the potential and the limits of christian theology within the historicist paradigm. (shrink)

Can time exist independently of consciousness? In antiquity this question was often framed as an enquiry into the relationship of time and soul. Aristotle cautiously suggested that time could not exist without a soul that is counting it. This proposal was controversially debated among his commentators. The present book offers an account of this debate beginning from Aristotle’s own statement of the problem in Book IV of the Physics. Subsequent chapters discuss Aristotle’s Peripatetic followers, Boethus of Sidon and Alexander of (...) Aphrodisias; his Neoplatonic readers, Plotinus and Simplicius; and early Christian authors, Gregory of Nyssa and Augustine. At the centre of the debate stood the relation between the subjective time in the soul and the objective time of the cosmos. Both could be seen as united in the world soul as the seat of subjective time on a cosmic scale. But no solution to the problem was final. No theory gained general acceptance. The book shows the fascinating variety and plurality of ideas about time and soul throughout antiquity. Throughout antiquity, the problem of time and soul remained as intriguing as it proved intractable. (shrink)

In view of a rapid succession of events in the contemporary world, on both the political and the scientific levels, it is indeed essential to say more about the subject of democracy in the civil society. If by democracy we mean not only a form of govern- ment but also a system of living, then indeed a unanimous judgment and also a general conception cannot be expected, but nevertheless the concept need not to be debased to the stage of complete (...) meaninglessness. (shrink)

The goal of the present article is to contribute to the epistemology and methodology of computer simulations. The central thesis is that the process of simulation modeling takes the form of an explorative cooperation between experimenting and modeling. This characteristic mode of modeling turns simulations into autonomous mediators in a specific way; namely, it makes it possible for the phenomena and the data to exert a direct influence on the model. The argumentation will be illustrated by a case study of (...) the general circulation models of meteorology, the major simulation models in climate research. (shrink)

Isaac Levi is more interested in inquiry and how it progresses than he is in metaphysics. Questions concerning the role of disposition predicates in inquiry are more central to him than those concerning the nature and reality of dispositions. It has not stopped him from giving me and others very useful metaphysical advice. Currently, where empirical metaphysics is in vogue, there is every reason to see whether the two forms of philosophical interest might interlock substantially. Levi has stimulating ideas indeed (...) on the two forms of philosophical interest, and has recently summarized them in the slogan: “The reality of dispositions is a work in progress”. We can learn much about what kinds of dispositions are acceptable from tracing and comparing the histories of successful and less successful disposition predicates in scientific inquiry. Levi explores one route along which dispositions become real. His idea is that the introduction of dispositions facilitates covering law explanation by increasing the number of laws. The successful disposition predicate eventually becomes integrated in scientific theory, much like an ordinary theoretical term, whereas the unsuccessful does not. My impression is that Levi thinks that this is the only way a disposition can become real. To evaluate this claim, an alternative course suggested by Jon Elster is introduced. I then try to bring out the differences between Levi's and Elster's views on dispositions, partly by suggesting that they resemble two aspects of full explanations discussed by Wesley Salmon. But more about that below. (shrink)

In recent years there has been much psychological and neurological work purporting to show that consciousness and self-awareness play no role in causing actions, and indeed to demonstrate that free will is an illusion. The essays in this volume subject the assumptions that motivate such claims to sustained interdisciplinary scrutiny. The book will be compulsory reading for psychologists and philosophers working on action explanation, and for anyone interested in the relation between the brain sciences and consciousness.

When it comes to evaluating reductive hypotheses in metaphysics, supervenience arguments are the tools of the trade. Jaegwon Kim and Frank Jackson have argued, respectively, that strong and global supervenience are sufficient for reduction, and others have argued that supervenience theses stand in need of the kind of explanation that reductive hypotheses are particularly suited to provide. Simon Blackburn's arguments about what he claims are the specifically problematic features of the supervenience of the moral on the natural have also been (...) influential. But most discussions of these arguments have proceeded under the strong and restrictive assumptions of the S5 modal logic. In this paper we aim to remedy that defect, by illustrating in an accessible way what happens to these arguments under relaxed assumptions and why. The occasion is recent work by Ralph Wedgwood, who seeks to defend non-reductive accounts of moral and mental properties together with strong supervenience, but to evade both the arguments of Kim and Jackson and the explanatory challenge by accepting only the weaker, B, modal logic. In addition to drawing general lessons about what happens to supervenience arguments under relaxed assumptions, our goal is therefore to shed some light on both the virtues and costs of Wedgwood's proposal. (shrink)

Recent controversy about the use of the vertebrate fossil record for external calibration of molecular clocks centers on two issues, the number of dates used for calibration and the reliability of the fossil calibration date. Viewing matters from a palaeontological perspective, we propose three qualitative, phylogenetic criteria that can be used within a comparative framework for the selection of well-constrained calibration dates from the vertebrate fossil record. On the basis of these criteria, we identify three highly suitable new fossil calibration (...) dates for molecular clock estimates: the lungfish–tetrapod split (between 419 and 408 Ma), the bird–crocodile split (between 251 and 243 Ma), and the alligator–caiman split (between 71 and 66 Ma). Together with our previously suggested bird–lizard split (between 252 and 257 Ma), these four fossil dates span a range of very different ages. They are, in our opinion, more suitable for molecular clock calibration than the traditionally used mammal–bird split, which is less well constrained. We plea for closer interactions between paleontologists and molecular biologists in studying the timescale of vertebrate evolution. BioEssays 27:1069–1075, 2005. © 2005 Wiley Periodicals, Inc. (shrink)

The idea of a ‘tobacco-free generation’ promises to make smoking a thing of the past by making cigarettes unavailable to birth cohorts in the future. If implemented, such a generational ban would lead to a society in which some individuals are allowed the freedom to smoke while others are not. This paper examines the ethical significance of this fact through the lens of ‘relational egalitarianism’, an approach to social justice that emphasises equal and respectful social relationships. It explores various dimensions (...) in which a society can fail to live up to the idea of equal status, such as the denial of moral agency, discrimination, stigmatisation, the unequal recognition of interests and violations of political equality. While acknowledging the complexity of practical and ethical challenges, the paper maintains that the generational ban need not violate egalitarian commitments. (shrink)

COVID-19 has substantially affected our lives during 2020. Since its beginning, several epidemiological models have been developed to investigate the specific dynamics of the disease. Early COVID-19 epidemiological models were purely statistical, based on a curve-fitting approach, and did not include causal knowledge about the disease. Yet, these models had predictive capacity; thus they were used to ground important political decisions, in virtue of the understanding of the dynamics of the pandemic that they offered. This raises a philosophical question about (...) how purely statistical models can yield understanding, and if so, what the relationship between prediction and understanding in these models is. Drawing on the model that was developed by the Institute of Health Metrics and Evaluation, we argue that early epidemiological models yielded a modality of understanding that we call descriptive understanding, which contrasts with the so-called explanatory understanding which is assumed to be the main form of scientific understanding. We spell out the exact details of how descriptive understanding works, and efficiently yields understanding of the phenomena. Finally, we vindicate the necessity of studying other modalities of understanding that go beyond the conventionally assumed explanatory understanding. (shrink)

In this essay, Johannes Giesinger comments on the current philosophical debate on educational justice. He observes that while authors like Elizabeth Anderson and Debra Satz develop a so-called adequacy view of educational justice, Harry Brighouse and Adam Swift defend an egalitarian principle. Giesinger focuses his analysis on the main objection that is formulated, from an egalitarian perspective, against the adequacy view: that it neglects the problem of securing fair opportunities in the competition for social rewards. Giesinger meets this objection (...) by expressing two basic theses: First, he argues that Brighouse and Swift themselves fail to give an adequate account of fair competition; and, second, he shows that the adequacy view provides the theoretical resources to face this problem. (shrink)

This important philosophical statement by an eminent scientist is written with such clarity and directness, and derives from so broad a humanistic perspective, that the thoughtful reader will find it as rewarding as it is instructive. The author's purpose in this undertaking is to: "...outline a system of thought in which notions or values can find a place along with the ideas of causal relationships that are applied in the physical sciences. The essential doctrine of this system, which is taken (...) from the metaphysical picture developed by Alfred North Whitehead... is the assumption that, in every act occurring in the universe, experience derived from that which has gone before is integrated with conceptions concerning possibilities in the future." Analyzing and extending Whitehead's picture, Dr. Burgers argues that the physical view of causality in itself is too restrictive for a general description of the universe, and is valid only for those phenomena where values are irrelevant. His concern is to introduce the entire panorama with its complementary physical and conceptual aspects in such a way that a wider view of causality is obtained, whereby an opening is found for the explanation of life. The author points out that the concept of "organism" implies "purpose," and is thus not amenable to complete description in the terms of molecular biology. Although most evolutionary steps are the result of unplanned chance effects, the recognition and conception of future possibilities are factors in the evolutionary trend: "The existence of matter is the result of persistent repetition of certain patterns. Matter is a set of habits of the universe; it is these habits which are studied in physics. [But] life is more than habit: it is the coordination of spontaneity... a struggle against mere randomness.... "It is the key of the philosophy here presented to consider expectations and valuations not as accidental by-products of physical states of matter, but as essential forms of functioning.". (shrink)

This work has been selected by scholars as being culturally important, and is part of the knowledge base of civilization as we know it. This work was reproduced from the original artifact, and remains as true to the original work as possible. Therefore, you will see the original copyright references, library stamps (as most of these works have been housed in our most important libraries around the world), and other notations in the work. This work is in the public domain (...) in the United States of America, and possibly other nations. Within the United States, you may freely copy and distribute this work, as no entity (individual or corporate) has a copyright on the body of the work. As a reproduction of a historical artifact, this work may contain missing or blurred pages, poor pictures, errant marks, etc. Scholars believe, and we concur, that this work is important enough to be preserved, reproduced, and made generally available to the public. We appreciate your support of the preservation process, and thank you for being an important part of keeping this knowledge alive and relevant. (shrink)

A condensed history of philosophy from the Pre-Socratics through to the 1960s, now extended to include the latest developments of Analytical philosopy. This new complemented edition follows the division of the original text into four parts: Ancient Philosophy, Medieval Philosophy, Modern Philosophy (17th and 18th century), and 19th and 20th century Philosophy. It contains a new preface and introduction, and a new fifth part on Analytical Philosophy by the Cambridge-based philosopher Clare Hay, carrying the story into the 21st century.

We claim that adjustable parameters play a crucial role in building and applying simulation models. We analyze that role and illustrate our findings using examples from equations of state in thermodynamics. In building simulation models, two types of experiments, namely, simulation and classical experiments, interact in a feedback loop, in which model parameters are adjusted. A critical discussion of how adjustable parameters function shows that they are boon and bane of simulation. They help to enlarge the scope of simulation far (...) beyond what can be determined by theoretical knowledge, but at the same time undercut the epistemic value of simulation models. (shrink)