Scholars have long noticed a similarity of motifs between Catullus’ Carmen 63 and the fifth book of the Odyssey, where the story of Odysseus’ captivity on Ogygia is narrated. A detailed analysis of the poems shows that Catullus wanted the reader to see in this Homeric episode a kind of matrix for the interpretation of Attis’ sojourn at Cybele. The discovery of this dependence casts a light on some of the hitherto proposed interpretations of Carmen 63.

Perhaps in last few centuries not any big theory has resulted in so much opposition as Darwinian theory of evolution. Within this theory, claim that _Homo sapiens _evolved from animal ancestors, namely apes, is undoubtedly the most controversial issue. Long tradition of teaching by Church that a pair of first people was created in short time in Eden Garden is in contradiction to discoveries of biology, including paleontology. If God exists, which is not the research subject of science, he created (...) human beings by a long process of biological Darwinian evolution followed by shorter process of non-Darwinian cultural evolution. Biologist must treat _Homo sapiens _as just one more species with long phylogeny, albeit special species characterized by brains of enormous size, with well-developed neocortex and very special mental traits being the consequence of such brain. The paper considers selection forces toward increase of this extremely expensive organ, draining at least 20% of energy. The main idea is that a series of positive feedbacks were responsible for the development of brain, correlated increase of intelligence and development of culture. Although no great breakthrough is required for such mode of evolution, energetic constrain limiting brain size was present through large part of our evolution, which was first broken by using primitive tools for cutting meat and grinding down seeds, then by thermal processing of food. The new constrain on skull size, and correlated brain size, that is the danger of death of both mother and child during childbirth, has been partly relieved by shifting large part of brain development to postnatal period. Resulting very long childhood was a prerequisite to cultural development of our species. (shrink)

Students of Thomas Aquinas have so far lacked a comprehensive study of his doctrine of the transcendentals. This volume fills this lacuna, showing the fundamental character of the notions of being, one, true and good for his thought. The book inquires into the beginnings of the doctrine in the thirteenth century and explains the relation of the transcendental way of thought to Aquinas's conception of metaphysics. It analyzes 'Being', 'One', 'True', 'Good' and 'Beautiful' individually and discusses their importance for the (...) philosophical knowledge of God. Medieval Philosophy and the Transcendentals: The Case of Thomas Aquinas is intended as a contribution to the question 'What is philosophy in the Middle Ages?' It argues that the doctrine of the transcendentals is essential for understanding medieval philosophy. (shrink)

Mathematical models are an important tool in the development ofsoftware technology, including programming languages and algorithms.During the last few years, a new class of such models has beendeveloped based on the notion of a mathematical game that isespecially well-suited to address the interactions between thecomponents of a system. This paper gives an introduction to thesegame-semantical models of programming languages, concentrating onmotivating the basic intuitions and putting them into context.

Cancers often express hundreds of genes otherwise specific to germ cells, the germline/cancer (GC) genes. Here, we present and discuss the hypothesis that activation of a “germline program” promotes cancer cell malignancy. We do so by proposing four hallmark processes of the germline: meiosis, epigenetic plasticity, migration, and metabolic plasticity. Together, these hallmarks enable replicative immortality of germ cells as well as cancer cells. Especially meiotic genes are frequently expressed in cancer, implying that genes unique to meiosis may play a (...) role in oncogenesis. Because GC genes are not expressed in healthy somatic tissues, they form an appealing source of specific treatment targets with limited side effects besides infertility. Although it is still unclear why germ cell specific genes are so abundantly expressed in cancer, from our hypothesis it follows that the germline's reproductive program is intrinsic to cancer development. (shrink)

After 1945, Czech philosophy and culture were first introduced to existentialism. First it was the original works of French existentialists (Sartre, Camus, Marcel), later by means of the journal Letters (1947) and Václav Černý (The first book on existentialism, 1948). The acceptance of existentialism in Czech context was not univocal. Besides factual analyses (J. Patočka, V. Navrátil, V. T. Miškovská), existentialism met with criticism and rejection mainly from Marxists and Catholic scholars for its rational weakness, pessimism, helplessness and intellectual decline.

The paper presents the sources and the development of the medieval doctrine of transcendentals. In Aertsen's opinion transcendental philosophy of the Middle Ages differs considerably from the ontological doctrine of the Ancients as well as from the modern theory referring to the sphere of cognition. The beginnings of the medieval doctrine of the transcendentals were inspired mostly by considerations concerning primary conceptions of human mind included in Avicenna's "Metaphysica". Furthermore, they were connected with the Aristotelian idea of science, the Boethian (...) axiomatic method of "common conceptions of the soul", and theologians' interest in the horizon of human intellectual knowledge. Beside the Aristotelian-Avicennian reduction to the most universal predicate Albert the Great acknowledge another reduction (originating from the Christian-Neoplatonic tradition): reduction to the first cause. In his opinion, these two resolutions are complementary to each other. In the philosophy of Thomas Aquinas, transcendentals are most fundamental insofar as they are the foundations of theoretical and practical science. The principle of contradiction – considered as the beginning of theoretical science – rests on the understanding of "being", and the first precept of natural law is founded on "the good". The development of the doctrine of the transcendentals in 13th century aloows to call the period "the second beginning of metaphysics" – since it changes the understanding of the proper subject of First Philosophy. In Albert the Great, for example, matephysics ceases to be the science of the divine, and becomes the science concerning what is first and the most fundamental – "being-as-being". In St. Bonaventure's philosophy, the doctrine of the transcendentals undergoes a theologizing transformation: that, which is first in the cognitive order is, at the same time, first ontologically. For Bonaventure, the latter "first" is God. (shrink)

Winnicotts Konzept des »Holding« bezieht sich auf das komplexe psychische Tun und Wirken der Mutter für ihr neugeborenes Kind, also darauf, dass sie sowohl als »Umwelt-Mutter« als auch als »Objekt-Mutter« fungieren muss. Während das Holding mit der Umwelt-Mutter assoziiert ist, möchte ich das »Containing« hier der Objekt-Mutter zuordnen. Es soll gezeigt werden, dass Winnicott diese Konzepte in Anlehnung an Freuds frühe Beobachtungen der für die emotionale Entwicklung des Kindes entscheidenden Rolle der Mutter erarbeitete. Obwohl die Rolle des Vaters ebenso wichtig (...) sei, betonte Winnicott, es liege in der Hand der Mutter, der Psyche des Kindes die Bedeutung des Vaters nahezubringen – oder nicht. Anknüpfend an Winnicotts späte Formulierungen aus »Objektverwendung und Identifizierung« wird vorgeschlagen, dass das psychische Überleben des Objekts die entscheidende interpsychische Dynamik im Kern der Eltern-Kind-Beziehung ist. Das intrapsychisch entstehende subjektiv überlebende Objekt gewinnt im Kontext der analytischen Situation potenziell an Stärke, wenn der Analytiker imstande ist, sein Überleben zu unterstützen. Um diese Themen kreist Winnicotts Objektbeziehungstheorie. (shrink)

The focus of this article is on an ambivalent conception in medieval thought, namely the term ‘transcendens’, which on the one hand signifies a reality beyond created beings, i.e. God, and on the other hand signifies something common to all beings. Armandus de Bellovisu, in his Declaratio difficilium terminorum, has thematized exactly this difference between transcendence that follows from ‘nobility of being’ and that which follows from ‘commonness of predication’ . The medieval term ‘transcendens’, because of its ambiguity, thus includes (...) two fundamental concepts, which represent divergent philosophical tendencies concerning the specification of First Philosophy: the one understands it as «Philosophy of Transcendence», the other as «Transcendental Philosophy». The history of metaphysics is characterized by the tension between these two tendencies, but as we shall see, it also shows that they are intimately connected. (shrink)

Since rules - legal, ethical or otherwise - cannot determine their own application, they require persons of flesh and blood to interpret and apply them in concrete cases. Presidents and prime ministers, judges, prosecutors, mediators, leaders of international organizations, and even religious leaders and public intellectuals make decisions on how best to understand rules and how best to apply them. It stands to reason that their character traits influence the sort of decisions they take. This book provides the first systematic (...) framework for discussing global governance in terms of the virtues, and illustrates it with a number of detailed examples of concrete decision-making in specific situations. Virtue in Global Governance combines insights from law, ethics, and global governance studies in developing a unique approach to global governance and international law. (shrink)