In this essay and the next, on Foucault, Derrida reencounters two thinkers to whom he had earlier devoted important essays, which precipitated stormy discussions and numerous divisions within the intellectual milieus influenced by their ...

Although many scientists view cloning as a useful procedure for scientific research into early embryo development—one that cannot currently be used to produce multiple copies of humans—the popular literature has led some individuals to view it as sinister. To address the concerns of the public, various conceptions of cloning are distinguished and their basis in fact analyzed. The possible uses, benefits, and detriments of both embryo splitting and nuclear transplantation are explained. Once the nature and purposes of cloning are understood, (...) and the distinctive ethical dilemmas created by embryo splitting and nuclear transplantation are sorted out, these procedures should be clinically implemented to assist in vitro fertilization treatment for those who are infertile and to further other therapeutic and investigational efforts in medicine. (shrink)

Deux textes composent cet adieu : l'hommage prononcé par Derrida aux obsèques d'Emmanuel Levinas suivi d'une lecture de Levinas à partir de la notion d'accueil et l'élaboration "subjugante" du concept d'accueil.

Theoretical minimal RNA rings attempt to mimick life’s primitive RNAs. At most 25 22-nucleotide-long RNA rings code once for each biotic amino acid, a start and a stop codon and form a stem-loop hairpin, resembling consensus tRNAs. We calculated, for each RNA ring’s 22 potential splicing positions, similarities of predicted secondary structures with tRNA vs. rRNA secondary structures. Assuming rRNAs partly derived from tRNA accretions, we predict positive associations between relative secondary structure similarities with rRNAs over tRNAs and genetic code (...) integration orders of RNA ring anticodon cognate amino acids. Analyses consider for each secondary structure all nucleotide triplets as potential anticodon. Anticodons for ancient, chemically inert cognate amino acids are most frequent in the 25 RNA rings. For RNA rings with primordial cognate amino acids according to tRNA-homology-derived anticodons, tRNA-homology and coding sequences coincide, these are separate for predicted cognate amino acids that presumably integrated late the genetic code. RNA ring secondary structure similarity with rRNA over tRNA secondary structures associates best with genetic code integration orders of anticodon cognate amino acids when assuming split anticodons (one and two nucleotides at the spliced RNA ring 5′ and 3′ extremities, respectively), and at predicted anticodon location in the spliced RNA ring’s midst. Results confirm RNA ring homologies with tRNAs and CDs, ancestral status of tRNA half genes split at anticodons, the tRNA-rRNA axis of RNA evolution, and that single theoretical minimal RNA rings potentially produce near-complete proto-tRNA sets. Hence genetic code pre-existence determines 25 short circular gene- and tRNA-like RNAs. Accounting for each potential splicing position, each RNA ring potentially translates most amino acids, realistically mimicks evolution of the tRNA-rRNA translation machinery. These RNA rings ‘of creation’ remind the uroboros’ (snake biting its tail) symbolism for creative regeneration. (shrink)

Cet ouvrage est une réédition numérique d’un livre paru au XXe siècle, désormais indisponible dans son format d’origine.

vant ce qui serait un unique modèle de gouvernement de l’intime, sont susceptibles de se moduler suivant les configurations familiales auxquelles elles s’adressent et de se construire dans des interactions multiples avec les exigences de ceux qu’elles visent. Même si l’histoire de la famille contemporaine est d’abord celle d’une autonomisation de la sphère privée et des individus qui la composent, par conséquent celle d’une autonomisation dans la détermination des liens familiaux, l’économie socio-politique de ces derniers, caractérisée par des types différents (...) d’interactions familiales, n’est jamais indépendante de positions et de dispositions sociales et des normes produites par les régulations publiques de la sphère privée. Ces dernières, loin d’être autogénérées, sui-. (shrink)

This paper outlines a phenomenological approach for describing physiological reactions occurring immediately after vital threats. This exemplified by data taken from previous studies relative to chemical intoxications of rats by a neurotoxical drug. The survival rate of the animals and the variations of their cerebral acetylcholinesterese activity are both reported as a function of the drug concentration, and with respect to their age. The collecting of the results may be described as the cusp, a bifurcation set of Thom's Catastrophe Theory.The (...) young animals react by a vital burst which modifies the shape of the cusp. A new fold or pocket takes place, changing it to the butterfly bifurcation set. This pocket supports the survival attractor concept, which appears reactional, transitory and variable in its intensity. (shrink)

The chronologic age classically used in demography is often unable to give useful information about which exact stage in development or aging processes has reached an organism. Hence, we propose here to explain in some applications for what reason the chronologic age fails in explaining totally the observed state of an organism, which leads to propose a new notion, the biological age. This biological age is essentially determined by the number of divisions before the Hayflick’s limit the tissue or mitochondrion (...) in a critical organ (in the sense where its loss causes the death of the whole organism) has already used for its development and adult phases. We give a precise definition of the biological age of an organ based on the Hayflick’s limit of its cells and we introduce a desynchronization index (the cell entropy) for some critical tissues or membranes, which are mainly skin, intestinal endothelium, alveoli epithelium and mitochondrial inner membrane. In these actively metabolising interface tissues or membranes, there is a rapid turnover of cells, of their cytoplasmic constituents such as proteins, and of membrane lipids. The boundaries corresponding to these tissues, cells or membranes have vital functions of interface with the environment (protection, homeothermy, nutrition and respiration) and have a rapid turnover (the total cell renewal time is in mice equal to 3 weeks for the skin, 1.5 day for the intestine, 4 months for the alveolae and 11 days for mitochondrial inner membrane) conditioning their biological age. The biological age of a tissue is made of two major components: (1) first, its embryonic age based on the distance (in number of divisions) between the birth date of its first differentiated cell and the time until it reaches its final boundary at the end of its development and (2) second, its adult age whose complement until its death is just the lapse of time made of the sum of remaining cell cycle durations authorized by its Hayflick’s limit. From this definition, we calculate the global biological lifespan of an organism and revisit notions like demographic survival curves, duration and synchrony of cell cycles, living boundaries from proto-cells to organs, and embryonic and adult phases duration. (shrink)

The imaginary has been inseparable, since prehistoric times, from technical artefacs, their forms, functions and uses. Gilbert Durand’s typologies can help to understand better the different technologies, their success, their effects, etc. Can we not go further by looking in the imaginary for one of the keys to technological innovation today which would allow an anthropological renovation of theoretical tools?

Cet article propose une synthèse sur les sources patristiques d’Isidore de Séville, qui est aussi un bilan des travaux les plus récents ou les plus significatifs sur le sujet. De fait, après avoir été longtemps sous-étudiées au profit des sources classiques, les sources patristiques d’Isidore sont de mieux en mieux connues. On en dispose maintenant d’une liste presque complète et il est possible de différencier celles qui sont très peu citées, celles qui sont moyennement utilisées et dont l’influence sur le (...) Sévillan semble relativement limitée, et celles qui sont très importantes, très souvent exploitées, parmi lesquelles dominent Ambroise, Jérôme, Grégoire le Grand et Augustin. (shrink)