Currently, the concept of the cell as a society or an ecosystem of molecular elements is gaining increasing acceptance. The basic idea arose in the 19th century, from the surmise that there is not just a single unit underlying an individual’s appearance, but a plurality of entities with both collaborative and conflicting relationships. The following hypothesis is based around this model. The incompatible activities taking place between different original elements, which were subsumed into the first cell and could not be (...) eliminated, had to be controlled very closely. Similarly, a strong level of control had to be developed over many cellular elements after the cell changed its genome to DNA. We assume that at least some of those original RNA agents and other biomolecules which carry incompatibilities and risks, are retained within current cells, although they are now under strict control. A virus functions as a signal informing these repressed cellular RNAs and other elements of ancient origin how to restore suppressed degrees of molecular freedom, favoring pre-existing molecular affinities and activities, re-establishing ancient molecular webs of interactions, and giving fragments of ancient coded information the opportunity to be re-expressed. Collectively, these newly activated mechanisms lead to different possibilities for pathological cell states. All these processes are opposed by cell-control mechanisms. Thus, in this new scenario, the battle is considered intracellular rather than between the virus and the cell. And so the virus is treated as the signal that precipitates the cell’s change from a latent to an active pathological state. (shrink)

En el presente artículo analizamos la Internet desde su origen hasta la actualidad considerándola como una unidad integrada por otras tecnologías de comunicación e información, donde todos tienen la posibilidad de hablar. A partir de esta condición inicial dividimos el análisis en dos direcciones: la red como tecno-capitalismo, y la red como «comunista», «comunitaria», «solidaria», «socialista», «democrática».

Los libros de doctrina o tratados pocas veces se hacen cargo de todas las consideraciones teóricas que están involucradas en exponer una materia. Estas consideraciones, por consiguiente, tienden a volverse una rutina que se repite sin muchas consecuencias. El propósito de este trabajo es presentar tres modelos con los que dentro de nuestra tradición, la latinoamericana, se han pensado las reglas sobre matrimonio, divorcio y paternidad. El fin último es enriquecer el debate contemporáneo sobre la reforma de estas reglas al (...) proporcionar herramientas, argumentos y perspectivas sobre los límites y oportunidades de cada modelo. (shrink)

The business world is facing a very complicated situation due to the COVID-19 pandemic. Small- and medium-sized companies —both in Spain and at the global level—are seeing their survival jeopardized by a fall in revenues. This scenario is aggravated in the case of micro-SMEs headed by female entrepreneurs. Accordingly, micro-SMEs, particularly those led by female entrepreneurs, need to reinvent themselves to overcome the current adversities that could lead to the destruction of their businesses and hence their jobs. One of the (...) ways to do this is to take advantage of digital transformation. Therefore, the aim of this paper is to analyze which variables influence the financial results of female-led Spanish micro-SMEs when they carry out social marketing actions. For that purpose, an online survey was designed and analyzed using the “PROCESS” macro. Results show that social media marketing actions have significant effects on financial performance. (shrink)

Rising economic inequality has aggravated long-standing labor market disparities, with one exception: government employment. This article considers the puzzle of black-white wage parity in the American public sector. African Americans are more likely to work in the public than in the private sector, and their wages are higher there. The article builds on prior work emphasizing institutional factors conditioning this outcome to argue that employee mobilization can motor it. As public sector unions gained political influence postwar, their large constituencies of (...) black, blue-collar workers, drawing on both militant and nonviolent tactics of the urbanizing civil rights movement, advocated for improved working conditions. Archival sources confirm this pattern at the federal level. The employment and activism of African Americans in low-skilled federal jobs pivoted union attention to blue-collar issues and directly contributed to the enactment of a transparent, universal wage schedule for the blue-collar federal workforce. The result was greater pay parity for African Americans, as well as for other disadvantaged groups. (shrink)

RESUMO Trata-se de aproximar Hume e Maquiavel, tomando-os como os expoentes de uma certa corrente não jusnaturalista, formada no início da idade moderna, quanto ao modo de pensar a natureza da lei e, num sentido amplo, a normatividade jurídico-política. Apesar de ter sofrido influência da escola moderna de direito natural, Hume rompe com ela num ponto fundamental - na recusa da noção de pessoa como ponto de partida para pensar a gênese social do ordenamento jurídico-político. No lugar disso, ele pensou (...) essa gênese a partir do jogo das forças sociais e da circulação das opiniões na sociedade, para o que Maquiavel se constituiu numa referência imprescindível. ABSTRACT This paper aims to bring together Hume and Machiavelli by taking both of them as exponents of a certain nonjusnaturalistic current, formed at the beginning of the modern age, which had its own way of thinking the nature of law and, in a broad sense, legal-political normativity. Despite being influenced by the modern school of natural law, Hume breaks with it in a fundamental point - in the refusal of the notion of person as a starting point to think the social genesis of the legal-political order. Instead, he thought of this genesis from the game of social forces and the circulation of opinions in society, for which Machiavelli was an indispensable reference. (shrink)

La distinción entre transmedia y cross-media con frecuencia resulta confusa en los estudios sobre la comunicación. Esta investigación tiene como objetivo revisar el uso de ambos conceptos en la literatura científica publicada en Web of Science y SciELO Citation Index. La investigación parte de una muestra de 895 artículos a los que se les aplica un análisis bibliométrico y un análisis de redes para descubrir las relaciones entre textos. Los resultados del estudio son útiles para conocer la configuración del campo (...) de conocimiento desde una perspectiva que integra las diversas disciplinas implicadas y abren el espectro para entender la comunicación transmedia y cross-media como objetos de estudio afines que deben ser estudiados de forma interdisciplinar. (shrink)

Utilizamos una herramienta de gamificación, un sistema de votación electrónica, en una asignatura a nivel universitario. Analizamos si el uso de dicha herramienta en las actividades de la evaluación continua repercutió o no en el proceso de enseñanza-aprendizaje, concretamente, en los resultados del examen final. Para ello recopilamos datos sobre las características del alumnado potencialmente influyentes en el rendimiento académico que estudiamos aplicando técnicas de análisis de datos descriptivas e inferenciales. El resultado muestra que el alumnado puede llegar a incrementar (...) hasta en casi 2 puntos su nota, según su ratio de aciertos con el sistema de votación electrónica. (shrink)

La Constitución de 1978 se ha convertido ya en el segundo texto de más larga duración en nuestra historia contemporánea, sólo superada por la Constitución de 1876, vigente durante cuarenta y siete años. Sin embargo, la situación real de una y otra no es comparable. Durante la vigencia del texto actual España ha sido modelo de significativos cambios, en la que se han dado muestras de prudencia y audacia, a la vez.

Durante el período Ilustrado hubo un discurso difundido que aclamaba la supremacía de la esfera económica sobre lo político y lo ético. Adam Ferguson, destacado filósofo de la Ilustración escocesa, no lo compartía, juzgándolo monolítico y reductor. Pensaba que la llegada de la sociedad comercial –del mercado-, decisiva para el progreso económico, fue también factor de desequilibrios que amenazaban el porvenir de la sociedad. Lo político era un elemento fundamental de la reproducción social. Se confrontaban dos modelos: uno basado en (...) el principio que parecía guiar, universalmente, las relaciones entre los hombres: el intercambio económico; y una representación de la sociedad civil basada en la virtud del ciudadano. Ferguson defendió el segundo: un hombre virtuoso no es el que serenamente contempla lo que pasa a su alrededor, sino aquel que ejerciendo su virtud activa mira a lo político. En esta perspectiva, lo virtuoso y lo político se encuentra estrechamente enlazados. (shrink)

Business ethics is one of the most significant demands made by institutional and individual investors, who usually require the participation of the board of directors in the planning and implementation of ethical behaviour in corporations. This is done by drawing up an ethics code and then monitoring its fulfilment. This study has a dual objective: first, to analyse the role played by the composition of the board of directors, and by that we mean its independence and the diversity of its (...) members, on the implementation and scope of an EC, and, second, to detect whether the corporate governance system moderates the level of involvement of the board in ethical issues. The findings obtained from a data panel sample made up of 760 listed companies from 12 countries for the years 2003–2009 show that the largest companies with large-sized and diverse boards implement the most developed ECs. Nevertheless, the extent of involvement of the independent directors is conditioned by the level of shareholder orientation characteristic of the system of CG in the corporation’s country of origin. (shrink)

This work has been selected by scholars as being culturally important, and is part of the knowledge base of civilization as we know it. This work is in the "public domain in the United States of America, and possibly other nations. Within the United States, you may freely copy and distribute this work, as no entity (individual or corporate) has a copyright on the body of the work. Scholars believe, and we concur, that this work is important enough to be (...) preserved, reproduced, and made generally available to the public. We appreciate your support of the preservation process, and thank you for being an important part of keeping this knowledge alive and relevant. (shrink)

A country‘s development is bound to be influenced by external occurrences. This article analyses two astronomical examples in which Portuguese nationals used high visibility events in the international scientific community to press their own scientific interests upon the government, whether these interests were, or were not, directly linked to the events themselves.During the 1840s and 1850s the parallax, i.e. the distance, of Groombridge’s star 1830 was hotly debated. The astronomer Hervé Faye‘s suggestion at the Académie des Sciences de Paris that (...) observations be made in Lisbon due to its privileged location and the inadequacy of the Lisbon Navy Observatory to perform them rekindled the efforts to improve the Portuguese Navy observatory.In the 1850s and 1860s other Portuguese higher education institutions also wanted to upgrade their facilities or build new ones. Following accepted traditions, scientific field trips were considered a useful part of the acquisition planning for larger instruments, and therefore an important part of regeneration and renewal projects. The Portuguese scientists were, however, limited in their travels by government imposed budget constraints. The total solar eclipse of 18 July 1860 provided an extra argument to send Portuguese scientists abroad. The government support of the eclipse expedition led to an opportunity to travel through other countries and view their observatories and equipment.In the end, neither the Navy astronomers nor those from the Coimbra Astronomical observatory, the other significant site of Portuguese astronomical research, managed to fulfil their objectives, but the contacts initiated by some of the Portuguese travellers were important for the development of the Portuguese national Meteorological and Magnetic Observatories. (shrink)

En este artículo analizo las críticas recientes de Judith Butler al escepticismo cartesiano y al constructivismo posmoderno (identificado con las obras de Preciado y Haraway), para explicar el distanciamiento de Butler respecto de posturas constructivistas y, al mismo tiempo, como un argumento para afirmar la dimensión ética y con pretensión de universalidad de su defensa de las vidas precarias.

The anatomical and physiological treatise Περὶ τῆς τοῦ ἀνθρώπου ἀνθρώπου κατασκευῆς is characterized by a peculiarity of medical terminology which is largely unknown from comparable texts: on the one hand, anatomical terms are put into relation with corresponding terms from poetic language, on the other hand they are precisely defined by descriptions of objects of everyday use. The considerable discrepancy between the Greek original and its Latin translation is of particular interest against the background of the renaissance of Περὶ τῆς (...) τοῦ ἀνθρώπου κατασκευῆς in the 16th century AD. The multiple versions of the Latin translation show that medical terminology in Latin language was still in an ongoing process of development, for which reason many Greek anatomical terms were inserted untranslated into the Latin text due to a lack of an adequate Latin equivalents. For this reason Περὶ τῆς τοῦ τοῦ ἀνθρώπου κατασκευῆς plays a central role in the development of anatomical terminology, but also in its becoming more and more specific and precise. (shrink)

Una de las organizaciones de la sociedad civil que ha adquirido gran relevancia en el combate a la pobreza alimentaria en el estado de Sonora es el Banco de Alimentos de Hermosillo (BAH). Su objetivo es combatir el hambre y la desnutrición mediante la distribución de alimentos a zonas marginadas. Pesqueira, es una de las localidades en situación crítica de pobreza alimentaria y que ha sido beneficiada por los apoyos que otorga el BAH. Sin embargo, a pesar de que esos (...) apoyos son reconocidos como una ayuda importante en términos de asistencia alimentaria, se desconoce objetivamente su impacto nutricional y económico. La metodología consistió en la tipificación de las canastas alimentarias (CA) durante un periodo de cuatro meses para contrastar su aporte nutricional y su valor en el mercado. Los resultados son los siguientes: de acuerdo a la composición nutrimental de la CA, es posible observar que sólo cubre el 20% de la ingestión diaria recomendada. En términos económicos, las CA han contribuido a que la población beneficiaria reduzca sus niveles de pobreza alimentaria en un 40%, aunque persiste la pobreza en términos absolutos. (shrink)