La infección por el virus del papiloma humano (VPH) constituye la causa necesaria, aunque no suficiente, de la enfermedad de transmisión sexual más frecuente en el mundo, responsable del 4,5 % de todos los cánceres en ambos sexos. La vacunación frente al VPH, con niveles de eficacia y seguridad similares en ambos sexos, está dirigida básicamente a mujeres, para reducir la incidencia de infección y sus consecuencias, como el cáncer de cérvix. La transmisibilidad del virus en ambos sexos y la (...) inmunidad colectiva que proporciona la vacunación universal hace que su extensión al sexo masculino constituya una cuestión no solo de salud pública, sino también un dilema bioético relacionado con la protección de la salud y la equitativa distribución de los recursos. Este trabajo aborda el análisis bioético de la extensión de la vacunación contra VPH a ambos sexos. (shrink)

The aim of this study was to examine the influence of somatic maturation in anthropometric, physical, and game-related variables in youth basketball age groups under-13 and under-15. One-hundred and eighty-five basketball players performed anthropometrical and physical tests during a non-official youth basketball tournament. Predicted maturity offset and game-related variables were also analyzed. Cluster analysis was used to analyze the between-maturation status differences in all parameters in each age group. Also, regularized generalized canonical correlation analysis was used to assess relative contributions (...) of maturational, physical, and game-related variables within each age group. Based on MO, two different clusters were identified within each age category. Greater differences in MO were identified among U-13 clusters than among U-15 clusters. No significant differences were observed between clusters in terms of physical and game-related variables. High correlations between maturational, physical, and game-related variables were found for boys. In girls, different trends in terms of correlations were observed. The strongest association between blocks was observed between physical tests and game-related variables in all age categories, except for U-15 girls. Knowing and identifying performance profiles according to biological age is of upmost importance since it allows the coach to create challenging situations adjusted to the individual’s needs. (shrink)

Although many important dieciochistas have devoted their attention to utopian texts written in Spain in the long eighteenth century, Form and Reform in Eighteenth-Century Spain: Utopian Narratives and Socio-Political Debate is the first book-length study of its kind. It is a book whose potential readership goes beyond the field of Spanish eighteenth-century specialists. It will interest global scholars in utopian studies and also Latin Americanists, especially those in the field of Colonial studies. The close reading of five utopian works...

A recent trend in bioethics has highlighted the decisive role that solidarity plays in global health. However, given the impact and extent of the effects of climate change, which reach beyond present generations, it is important to consider whether this concept can be applied intergenerationally. Does it make sense to talk about solidarity with future generations? The objective of this article is to explore ‘amplified solidarity’, a new concept of solidarity that explains our obligations towards the health and quality of (...) life of future generations. The analysis of this concept is structured as follows: I first establish the moral relevance of future people and then investigate the traits of amplified solidarity, its challenges, and its relationship with other key principles. I propose that amplified solidarity needs both a critical imagination to be projected towards the future and an institutional framework to correct health injustices across an intergenerational timescale. Solidarity forms a potent triangular constellation with responsibility and justice to fight against global and intergenerational injustices. (shrink)

The native language changes as a result of contact with a second language, and the pattern and degree of such change depend on a variety of factors like the bilingual experience or the linguistic level. Here, we present a systematic review and meta-analysis of works that explore variations in native sentence comprehension and production by comparing monolinguals and bilinguals. Fourteen studies in the meta-analysis provided information regarding the bilingual experience and differences at the morphosyntactic level using behavioral methods. Overall, we (...) observed that first language processing is subject to small transformations in bilinguals that occur in sentence comprehension and production. The magnitude of the changes depended on bilingual experiences, but only length of residence in an L2 setting predicted the degree of change, where shorter length of residence was associated with larger changes. Results are discussed and related to the cognitive processes that potentially cause the transformations in the first language. The present work reveals some limitations in the field that should be addressed in future studies to better understand the mechanisms behind language attrition. (shrink)

Small GTPases in the Rho family act as major nodes with functions beyond cytoskeletal rearrangements shaping the Caenorhabditis elegans embryo during development. These small GTPases are key signal transducers that integrate diverse developmental signals to produce a coordinated response in the cell. In C. elegans, the best studied members of these highly conserved Rho family small GTPases, RHO‐1/RhoA, CED‐10/Rac, and CDC‐42, are crucial in several cellular processes dealing with cytoskeletal reorganization. In this review, we update the functions described for the (...) Rho family small GTPases in spindle orientation and cell division, engulfment, and cellular movements during C. elegans embryogenesis, focusing on the Rho subfamily Rac.Please also see the video abstract here. (shrink)

Psychological flexibility is a key concept of acceptation and commitment therapy. This factor has been linked with psychological wellbeing and associated factors, such as quality of life, in cancer patients. These and other positive results of acceptation and commitment therapy in cancer patients found in previous research could be enhanced by using mhealth tools. A three-arm randomized superiority clinical trial, with a pre-post-follow-up repeated measures intergroup design with a 1:1:1 allocation ratio is proposed. A hundred and twenty cancer patients will (...) be randomly assigned to one of the following interventions: face-to-face ACT + mobile application, face-to-face ACT, and Waitlist control group. The primary expected outcome is to observe significant improvements in psychological flexibility acceptance and action questionnaire- II in the face-to-face ACT + app group, after comparing baseline and post-treatment scores, and the scores will remain stable in the two assessment points, 3 and 6 months after the intervention. Secondary expected outcomes are significant increasing scores in quality of life and post-traumatic-growth, and significant decreasing scores in anxiety and depression, insomnia and fatigue at the same assessment points. Also, it is expected that the scores of this group will be higher than the scores of the face-to-face ACT group and the waitlist control group. This study aims to assess the efficacy of a combined intervention for psychological flexibility and associated symptoms in cancer patients. The results of this protocol may help to consider the use of acceptation and commitment therapy and mhealth applications in cancer settings as a valid therapeutic choice.Clinical Trial Registration[www.ClinicalTrials.gov], identifier [NCT05126823]. (shrink)

Introduction: Physical distancing under the coronavirus disease 2019 pandemic had a significant impact on lifestyles, including exercise routines. In this study, we examined the relationship between mental health and addictive behaviors, such as excessive exercise and the use of image and performance enhancing drugs across 12 sport disciplines.Materials and methods: A large cross-sectional sample of the adult population was surveyed. The mean age was 33.09. The number of male participants was 668. The use of IPEDs was assessed in conjunction with (...) psychometric measures such as the Exercise Addiction Inventory and the Appearance Anxiety Inventory. The participants were grouped into activity group and non-activity group according to the presence or absence of their exercise habits. The results were compared between these groups, as well as across sport disciplines, while taking into account the relationship between different psychological measures and IPEDs consumption.Results: The frequency of IPEDs use was higher among AG than NAG, although AG participants reported less history of addictions than NAG. The logistic regression analysis revealed that scores equal to or above cutoff points, in both the EAI and AAI, predicted the IPEDs use. Regarding the differences across the various sport disciplines, those who were involved in practicing Weight Lifting and Cross Fit were found to be more at risk of excessive exercising and more inclined to use a wide range of IPEDs.Conclusions: Although exercise could help to increase well-being and prevent addictions during the COVID-19 pandemic, our results show that those in the AG are particularly vulnerable to excessive IPEDs use. Sport disciplines associated with higher EAI and AAI scores have also shown a higher tendency to excessive IPEDs use. Furthermore, the factor of having above the cutoff scores in EAI or AAI in each sport could indicate larger IPEDs consumption regardless of the discipline. In light of the current findings, it is necessary to better define the “non-excessive” levels of exercise in various sport disciplines and an adequate intake of IPEDs to ensure the safety and well-being of people during a pandemic. (shrink)

En el momento actual de crisis climática, de inestabilidad de los sistemas económicos y políticos, las teorías éticas deben responder a dilemas urgentes de justicia intergeneracional, en especial, a la pregunta de qué le debemos a las generaciones futuras. -/- Esta inspiradora obra, a diferencia de las teorías predominantes, se adentra en cuatro regiones problemáticas de la justicia intergeneracional –la incertidumbre epistémica, los derechos de los no nacidos, la justicia entre generaciones que no conviven y las razones por las cuales (...) nos deberíamos preocupar por la calidad de vida de las personas del futuro– desde una de las perspectivas más exitosas de la justicia social, la teoría arraigada en las «capacidades». Es así como, partiendo de lo que las personas efectivamente pueden «hacer» y «ser», de las oportunidades reales, este libro brilla de manera original en su apuesta por una nueva categoría de responsabilidad que se comprometa con la fragilidad que el ser humano ha creado, la cual no tiene precedentes hasta ahora. -/- Con un lenguaje claro, salpicado de casos concretos que ilustran el camino, Irene Gómez Franco afronta con maestría esta tarea al conjugar cuestiones que van de la ética, a la política, la economía y los estudios medioambientales, ahondando en temas como los derechos de las mujeres, la democracia y la razón pública, los intereses de la comunidad, el ecocidio y la sostenibilidad de las libertades. -/- El resultado es una obra de afinada sensibilidad práctica, imprescindible para todo aquel interesado en la construcción de un futuro donde la vida humana sea más justa y digna. (shrink)

Gómez Franco, Irene (2021)Deudas pendientes: La justicia entre generacionesMadrid: CSIC / Plaza y Valdés Editores, 384 p.ISBN CSIC: 978-84-00-10728-4ISBN Plaza y Valdés: 978-84-17121-32-7.

Traducción del alemán de Irene Borges-Duarte.

Tarski implicitly postulated that a certain pre-theoretical concept of logical consequence and his technical concept of logical consequence are co-extensional. This chapter makes explicit a few theses about logical consequence or logical truth that sound Tarskian somehow, including one that most deserves the name ‘Tarski's Thesis’. Some of these theses are probably true or close to true but weaker than Tarski's. Some are false but stronger than Tarski's. Tarski's Thesis plausibly postulated that a sentence of a classical language possibly extended (...) with non-traditional extensional logical constants is logically true, if it is true in all classical interpretations of all its non-logical constants. But it is noted that this thesis turns out to be false on most conceptions of logical truth, for some sentences of a classical language extended with extensional logical constants are true in all classical interpretations of all its non-logical constants, but are not necessary. (shrink)

I postulate that the extension of a degree adjective is fixed by implicitly accepted non-analytic reference-fixing principles (“preconceptions”) that combine appeals to paradigmatic cases with generic principles designed to expand the extension of the adjective beyond the paradigmatic range. In regular occasions of use, the paradigm and generic preconceptions are jointly satisfied and determine the existence of an extension/anti-extension pair dividing the adjective’s comparison class into two mutually exclusive and jointly exhaustive subclasses. Sorites paradoxical occasions of use are irregular occasions (...) of use in which the paradigm and generic preconceptions are not jointly satisfied. In them, the relevant degree adjective lacks an extension, and utterances of sentences containing it appearing in sorites arguments do not have truth conditions. I also postulate a probable psychology of paradigm intuitions, used in a psychological explanation of the preference for solutions of the sorites paradox on which paradigm preconceptions retain their intuitive truth-values. (shrink)

El presente artículo tiene por objeto el estudio de las melodías y textos de los himnos de vísperas, laudes y maitines del oficio proprio de las santas Justa y Rufina en los libros de coro de la Catedral de Sevilla.

Quotation marks are ambiguous, although the conventional rules that govern their different uses are similar in that they contain quantifications over quotable expressions. Pure uses are governed by a simple rule: by enclosing any expression within quotation marks one gets a singular term, the quotation, that stands for the enclosed expression. Impure uses are far less simple. In a series of uses the quotation marks conventionally indicate that (part of) the enclosed expression is a contextually appropriate version of expressions uttered (...) by some relevant agent. When the quotation marks have this meaning, it is tempting to think of them as contributing that indication to the truth-conditional content of the utterance. I adopt a cautious attitude towards this hypothesis, for the evidence in its favor is inconclusive. In other uses the quotation marks conventionally indicate that the enclosed expression should be used not “plainly” but in some broadly speaking “distanced” way, or that it is being so used by the utterer, and typically context makes clear the exact nature of the “distance” at stake. In these cases the quotation marks do not even appear to contribute that indication to the truth-conditional content of the utterance. (shrink)

An exposition of Kripke's unpublished critique of dispositionalism about color, followed by a review of some recent defenses of dispositionalism and a sketch of some objections that could be made to these defenses from a broadly Kripkean perspective.

Student-centered pedagogy has been embraced by many feminist practitioners and educational theorists as an antidote to more “traditional” or “masculinist” forms of classroom relations, epistemological constructs, and theories of self. I will show that the margin-center schema, student-centered pedagogy’s foundational metaphor, undermines feminist projects when applied to teacher-student relations. Although the margin-center schema has been a useful diagnostic tool in feminist theory, it operates prescriptively in student-centered pedagogy. Student-centered pedagogy designates teachers’ “proper place” at the margins of classroom life, a (...) place that echoes bygone visions of domestic femininity. This paper is simultaneously a critique of student-centered pedagogy and a recuperative project to dislodge the work of John Dewey from the teacher-centered/student-centered binary. (shrink)

Gustav Theodor Fechners (1801-1887) philosophische, ethische und ästhetische Überlegungen, die anders als seine naturwissenschaftlichen Arbeiten der Öffentlichkeit weniger bewußt sind, werden in diesem Band, Ergebnis eines zu seinem 200. Geburtstag an der Universität Leipzig veranstalteten interdisziplinären Kolloquiums, in ihren Wirkungen auf die Geisteswissenschaften des 20. Jahrhunderts aus philosophischer, theologischer, linguistischer, kultur- und literaturwissenschaftlicher sowie wissenschaftshistorischer Sicht erörtert - mit Blick auf seine interdisziplinäre Leistung und unter Einbeziehung biographischer Aspekte.

The case of Baby G raises some of the most difficult decisions confronting parents and health-care professionals. Given the context-specific nature of most medical decisions affecting children, the principles and standards of child rights and the U.N. Convention on the Rights of the Child will not clearly articulate the best interests of the child in every situation. A child rights–based approach will, however, provide the factors that must be considered, methods for their analysis, and the procedural safeguards that must surround (...) decision-making related to complex medical situations facing children, families, and providers. This approach can facilitate both.. (shrink)

The distinction between non-symbolic and symbolic number is poorly addressed by the authors despite being relevant in numerical cognition, and even more important in light of the proposal that the approximate number system represents rational numbers. Although evidence on non-symbolic number and ratios fits with ANS representations, the case for symbolic number and rational numbers is still open.

En este artículo se examina la propuesta de R. Axelrod acerca de cómo emerge y se hace estable la cooperación en un modelo de Dilema del Prisionero reiterado, con la estrategia Toma y Daca y con jugadores egoístas racionales. Se demuestra que esta estrategia es efectiva para la cooperación si los jugadores ganan, o al menos si no pierden con su cooperación. Esto tiene como consecuencia una alteración del orden de pagos típico del Dilema del Prisionero, por lo que se (...) mantiene que la cooperación entre egoístas racionales en términos de Toma y Daca es posible porque los jugadores no están en un Dilema del Prisionero. La estructura de su situación se encuentra mejor representada por otros juegos (reiterados). (shrink)

When quotations are used with a purely referential purpose, they are mostly used with the purpose of referring to expressions, in the sense of rather abstract expression types. However, in many cases purely referential quotations are used with the purpose of referring to things other than very abstract expression types, such as boldface types, sounds, particular tokens, etc. The paper deals with the question of what mechanism underlies the possibility of successfully referring to different things and kinds of things with (...) one and the same quotation. I defend the view that a quotation has as its semantic reference a certain very abstract expression type, and that the possibility of referring to other things by means of it is to be explained as a pragmatic phenomenon of felicitously conveyed speaker reference. (shrink)

Fibromyalgia is a chronic pain syndrome characterized by dysfunctional processing of nociceptive stimulation. Neuroimaging studies have pointed out that pain-related network functioning seems to be altered in these patients. It is thought that this clinical symptomatology may be maintained or even strengthened because of an enhanced expectancy for painful stimuli or its forthcoming appearance. However, neural electrophysiological correlates associated with such attentional mechanisms have been scarcely explored. In the current study, expectancy processes of upcoming laser stimulation (painful and non-painful) and (...) its further processing were explored by event-related potentials (ERPs). Nineteen fibromyalgia patients and twenty healthy control volunteers took part in the experiment. Behavioral measures (reaction times and subjective pain perception) were also collected. We manipulated the pain/no pain expectancy through an S1–S2 paradigm (cue-target). S1 (image: triangle or square) predicted the S2 appearance (laser stimulation: warmth or pinprick sensation). Laser stimuli were delivered using a CO2 laser device. Temporal and spatial principal component analyses were employed to define and quantify the ERP component reliability. Statistical analyses revealed the existence of an abnormal pattern of pain expectancy in patients with fibromyalgia. Specifically, our results showed attenuated amplitudes at posterior lCNV component in anticipation of painful stimulation that was not found in healthy participants. In contrast, although larger P2 amplitudes to painful compared to innocuous events were shown, patients did not show any amplitude change in this laser-evoked response as a function of pain predictive cues (as occurred in the healthy control group). Additionally, analyses of the subjective perception of pain and reaction time indicated that laser stimuli preceded by pain cues were rated as more painful than those signaling non-pain expectancy and were associated with faster responses. Differences between groups were not found. The present findings suggest the presence of dysfunction in pain expectation mechanisms in fibromyalgia that eventually may make it difficult for patients to correctly interpret signs that prevent pain symptoms. Furthermore, the abnormal pattern in pain expectancy displayed by fibromyalgia patients could result in ineffective pain coping strategies. Understanding the neural correlates of pain processing and its modulatory factors is crucial to identify treatments for chronic pain syndromes. (shrink)

As religiões podem ser consideradas como sistemas simbólicos mediante os quais os seres humanos ao longo da sua história sempre procuraram encontrar sabedoria em ordem a enfrentar o mal Um olhar pela história das religiões oferece-nos dados que podem ser compreendidos a partir de três tipos ideais de atitude básica em relação ao problema: Ascese, Gnose, Praxis. O Budismo originário, o Maniqueísmo e a religião bí-blico-cristã são exemplificações disso mesmo. Mais do que uma opção pela exclusão, os membros da nossa (...) cultura ocidental iluminada demonstram uma preferência pela atitude práxica. É a partir dela que nos cabe recuperar os valores das outras. Isso é também o que em muitos significa a presença de uma certa nostalgia pela "espiritualidade oriental". Ou ainda, como modesta gnose, a "teodiceia" (porquê tanto mal?): tão pouco prometedora enquanto resposta (teórica), como inevitável enquanto pergunta. /// Religions can be viewed as symbolic systems with which human beings have throughout history sought the wisdom which enables them to face evil. A survey through the history of religions exhibits features which may be brought to three ideal types of basic attitudes: the ascetic, the gnostic and the 'praxical'. Original Buddhism, Manichaeism and the biblical-Christian Religion exemplify them. Men and women of our occidental, enlightened culture need not to take an exclusive option thereabout. They show a preference for the praxical trend, even though at the same time they also retrieve some of the values of the other ones. Signs of this can be seen in the interest of many for 'oriental spirituality' as well as in that sort of modest gnosis which is "theodicee "(Why so much evil?): always unpromising as a theoretical answer and unavoidable as a question. /// Las religiones pueden ser consideradas como sistemas simbólicos con los que los seres humanos hemos buscado en nuestra historia una sabiduría para afrontar el mal. Un recorrido por la historia de las religiones ofrece datos que pueden comprenderse desde tres tipos ideales de actitud básica de afrontamiento: Ascesis, Gnosis, Praxis. El Budismo originário, el Maniqueísmo y la Religión bíblico-cristiana los ejemplifican. Más que una opción excluyente, los humanos de nuestra cultura occidental ilustrada tendrán una preferencia por la actitud práxica. Cabe desde ella recuperar valores de las otras. Eso hace en muchos la añoranza por la "espiritualidad oriental". Y, como modesta gnosis, la "teódicea" (¿por qué tanto mal?): tan poco prometedora como respuesta (teórica), cuanto insoslayable como pregunta. (shrink)