My dissertation asks how we affect conversational context and how it affects us when we participate in any conversation—including philosophical conversations. Chapter 1 argues that speakers make pragmatic presuppositions when they use proper names. I appeal to these presuppositions in giving a treatment of Frege’s puzzle that is consistent with the claim that coreferential proper names have the same semantic value. I outline an explanation of the way presupposition carrying expressions in general behave in belief ascriptions, and suggest that substitutivity (...) failure is a special case of this behavior. Chapter 2 develops a compositional probabilistic semantics for the language of subjective uncertainty, including epistemic adjectives scoped under quantifiers. I argue that we should distinguish sharply between the effects that epistemically hedged statements have on conversational context, and the effects that they have on belief states. I also suggest that epistemically hedged statements are a kind of doxastic advice, and explain how this hypothesis illuminates some otherwise puzzling phenomena. Chapter 3 argues that ordinary causal talk is deeply sensitive to conversational context. The principle that I formulate to characterize that context sensitivity explains at least some of the oddness of ‘systematic causal overdetermination,’ and explains why some putative overgenerated causes are never felicitously counted, in conversation, as causes. But the principle also makes metaphysical theorizing about causation rather indirectly constrained by ordinary language judgments. (shrink)

For a variety of reasons, it's difficult to determine, with any accuracy, the number of trans and gender nonbinary folks living in the United States.1 Data are difficult to obtain since neither the U.S. Census Bureau nor the Centers for Disease Control and Prevention survey people's gender identity. But even if they did, responses would likely be unreliable. Many members of these two groups are hesitant to answer such questions for fear of their safety, resulting discrimination, or because they disagree (...) on the definition of what it means to be transgender. It's also difficult to obtain accurate numbers on these groups since most medical forms still rely on a two-sex system of... (shrink)

A long-range potential is one whose range, the distance of effective influence, is unbounded or infinite. In this paper we show, using a definition of the range of a potential and certain other theoretical considerations, that the only long-range potential isV(r)=c/r, wherec is a constant.

According to the prevailing paradigm in social-cognitive neuroscience, the mental states of individuals become shared when they adapt to each other in the pursuit of a shared goal. We challenge this view by proposing an alternative approach to the cognitive foundations of social interactions. The central claim of this paper is that social cognition concerns the graded and dynamic process of alignment of individual minds, even in the absence of a shared goal. When individuals reciprocally exchange information about each (...) other's minds processes of alignment unfold over time and across space, creating a social interaction. Not all cases of joint action involve such reciprocal exchange of information. To understand the nature of social interactions, then, we propose that attention should be focused on the manner in which people align words and thoughts, bodily postures and movements, in order to take one another into account and to make full use of socially relevant information. (shrink)

The hypergrowth and hyperconnectivity of networks of artificial intelligence (AI) systems and algorithms increasingly cause our interactions with the world, socially and environmentally, more technologically mediated. AI systems start interfering with our choices or making decisions on our behalf: what we see, what we buy, which contents or foods we consume, where we travel to, who we hire, etc. It is imperative to understand the dynamics of human-computer interaction in the age of progressively more competent AI. This essay presents (...) five premises to serve as starting points for building our understanding of the “interactions’ in human-computer interactions. (shrink)

DNA transfer directly from cell to cell (conjugation) is common among prokaryotes, particularly Gram‐negative bacteria like Escherichia coli. The phenomenon invariably requires a set of plasmid genes in the DNA donor cell. In addition, E. coli itself makes limited and specific contributions to the donor activity of strains carrying the conjugative plasmid F. These contributions have yet to be defined biochemically, but it is already clear that the cell envelope is an importan nexus between plasmid‐ and chromosome‐encoded proteins required for (...) the establishment and maintenance of DNA donor activity. (shrink)

The contributions to this volume, which take into account literary, visual, and other types of evidence, show that animals and humans in Graeco-Roman antiquity are interconnected on a variety of different levels and that their encounters and interac.

Diversity, equity, and inclusion (DEI) policies and programs are crucial tools for reducing social inequality within organizations. However, the recent decline in DEI practices and the inconsistencies found in existing research underscore the need for new theoretical approaches. This essay seeks to offer a fresh perspective on the strengths and limitations of DEI initiatives through the lens of granular interactions thinking theory. It posits that while DEI policies and programs generally create conditions conducive to greater value creation and improved (...) adaptability to changing environments and challenges, maintaining direction and operational certainty within an organization with high DEI demands significant energy investment. To sustain DEI and enhance its effectiveness, these policies need to go beyond simply increasing diversity and ensuring equal access to opportunities. They must also focus on empowering a diverse workforce to contribute to the organization’s success actively. Additionally, fostering a workplace culture that enhances members’ adaptive cognitive processing and skills can reduce the energy required to sustain DEI efforts, making these practices more sustainable in the long term. (shrink)

Using data on submitted and published manuscripts in Feminist Economics from 1995 to 2019, we examine differences in method and scope used by authors residing in the Global North and Global South. We specifically focus on research methods, intersectional analyses, region of analysis, and co-authorship status. Further, using logistic regression models, we examine the relationship between authors’ location and use of research methods. We find authors in the Global South are more likely to engage in empirical and mixed-methods papers compared (...) to Global North authors in our sample. Moreover, a greater share of Global South authors engage in intersectional analysis and exhibit geographical focus on developing countries. Drawing insights from the Feminist Economics manuscripts data, we argue that encouraging Global South research can contribute to the goals of the field of feminist economics – aimed at inclusivity, diversity of standpoints, and plurality in research methods, thereby improving overall economic research. (shrink)

The first clinical symptoms focused on the presentation of coronavirus disease 2019 have been respiratory failure, however, accumulating evidence also points to its presentation with neuropsychiatric symptoms, the exact mechanisms of which are not well known. By using a computational methodology, we aimed to explain the molecular paths of COVID-19 associated neuropsychiatric symptoms, based on the mimicry of the human protein interactions with SARS-CoV-2 proteins.Methods: Available 11 of the 29 SARS-CoV-2 proteins’ structures have been extracted from Protein Data Bank. (...) HMI-PRED, a recently developed web server for structural PREDiction of protein-protein interactions between host and any microbial species, was used to find the “interface mimicry” through which the microbial proteins hijack host binding surfaces. Classification of the found interactions was conducted using the PANTHER Classification System.Results: Predicted Human-SARS-CoV-2 protein interactions have been extensively compared with the literature. Based on the analysis of the molecular functions, cellular localizations and pathways related to human proteins, SARS-CoV-2 proteins are found to possibly interact with human proteins linked to synaptic vesicle trafficking, endocytosis, axonal transport, neurotransmission, growth factors, mitochondrial and blood-brain barrier elements, in addition to its peripheral interactions with proteins linked to thrombosis, inflammation and metabolic control.Conclusion: SARS-CoV-2-human protein interactions may lead to the development of delirium, psychosis, seizures, encephalitis, stroke, sensory impairments, peripheral nerve diseases, and autoimmune disorders. Our findings are also supported by the previous in vivo and in vitro studies from other viruses. Further in vivo and in vitro studies using the proteins that are pointed here, could pave new targets both for avoiding and reversing neuropsychiatric presentations. (shrink)

Large‐scale patterns of correlated growth in development are partially driven by competition for metabolic and informational resources. It is argued that competition between organs for limited resources is an important mesoscale morphogenetic mechanism that produces fitness‐enhancing correlated growth. At the genetic level, the growth of individual characters appears independent, or “modular,” because patterns of expression and transcription are often highly localized, mutations have trait‐specific effects, and gene complexes can be co‐opted as a unit to produce novel traits. However, body parts (...) are known to interact over the course of ontogeny, and these reciprocal exchanges can be an important determinant of developmental outcomes. Genetic mechanisms underlie cell and tissue behaviors that allow organs to communicate with one another, but they also create evolutionarily adaptive competitive dynamics that are driven by physiological and biophysical processes. Advances in the understanding of competitive and closely related coordinative interactions across scales will complement existing research programs that emphasize the role of cellular mechanisms in morphogenesis. Study of the large‐scale order produced by competitive dynamics promises to facilitate advances in basic evolutionary and developmental biology, as well as applied research in fields such as bioengineering and regenerative medicine that aim to regulate patterning outcomes. (shrink)

Background: The classical symptom specificity hypothesis (Blatt, 1974) links obsessional symptoms to autonomous interpersonal behavior. Inconsistent findings from cross-sectional group studies on symptom specificity have previously been associated with several conceptual and methodological limitations intrinsic to nomothetic research. Previous empirical case research reported ambivalences between autonomous and dependent interpersonal behavior in obsessional pathology. Aim and Method: The present ‘theory-building’ case study specifically aims at further refinement of the classical symptom specificity hypothesis by testing specific operationalizations within an empirical single case (...) design. Consensual Qualitative Research for Case studies is used to quantitatively and qualitatively describe the longitudinal, clinical interplay between obsessional symptoms and interpersonal dynamics throughout the process of a psychodynamic therapy. Interpersonal functioning is assessed by means of the Core Conflictual Relationship Theme method. The classical symptom specificity hypothesis is contrasted to an alternative hypothesis of interpersonal ambivalences as determinants of obsessional symptoms. Results: Close associations between obsessions and interpersonal dynamics are observed. Findings predominantly affirm the ambivalence hypothesis rather than the classical symptom specificity hypothesis. Psychodynamic interventions focusing on interpersonal conflicts are related to symptomatic changes. Conceptual and methodological considerations, limitations and future research indications are discussed. (shrink)

The aim of our study is to show the ways in which family members coordinate their minds, bodies and language in a functional and goal-oriented manner when they are jointly remembering shared events that they had experienced together as a group. So far, little attention has been paid to the influence that the interplay of multiple behavioral channels have in collaborative remembering in small groups. Our goal is to specifically examine the central role that direct questions have when they act (...) as embodied reminders through the interanimation of multiple behavioral channels in family interactions. The video data for analysis comes from an ongoing project on how collaborative remembering takes places among small groups of Argentinean Spanish speakers as each group recalls a vacation taken together several years ago. (shrink)

Language learning is not primarily driven by a motivation to describe invariant features of the world, but rather by a strong force to be a part of the social group, which by definition is not invariant. It is not sufficient for language to be fit for the speaker's perceptual motor system. It must also be fit for social interactions.

Across species, animals have an intrinsic drive to approach appetitive stimuli and to withdraw from aversive stimuli. In affective science, influential theories of emotion link positive affect with strengthened behavioural approach and negative affect with avoidance. Based on these theories, we predicted that individuals’ positive and negative affect levels should particularly influence their behaviour when innate Pavlovian approach/avoidance tendencies conflict with learned instrumental behaviours. Here, across two experiments – exploratory Experiment 1 (N = 91) and a preregistered confirmatory Experiment 2 (...) (N = 335) – we assessed how induced positive and negative affect influenced Pavlovian-instrumental interactions in a reward/punishment Go/No-Go task. Contrary to our hypotheses, we found no evidence for a main effect of positive/negative affect on either approach/avoidance behaviour or Pavlovian-instrumental interactions. However, we did find evidence that the effects of induced affect on behaviour were moderated by individual differences in self-reported behavioural inhibition and gender. Exploratory computational modelling analyses explained these demographic moderating effects as arising from positive correlations between demographic factors and individual differences in the strength of Pavlovian-instrumental interactions. These findings serve to sharpen our understanding of the effects of positive and negative affect on instrumental behaviour. (shrink)

As the ubiquity of technology-mediated communication grows, so does the number of questions about the costs and benefits of replacing in-person interactions with technology-mediated ones. In the present study, we used a daily diary design to examine how people’s emotional experiences vary across in-person, video-, phone-, and text-mediated interactions in day-to-day life. We hypothesised that individuals would report less positive affect and more negative affect after less life-like interactions (where in-person is defined as the most life-like and (...) text-mediated as the least life-like). In line with this hypothesis, the analysis of 527 unique interactions reported by 102 individuals (mean age = 19.3; 85.6% female) over the course of 7 days reveals that people feel lonelier, sadder, less affectionate, less supported, and less happy following less life-like interactions. Additional analyses show that the links between life-like communication and momentary experiences are independent of properties of individual interactions such as interaction length and participants’ overall evaluations of interaction quality. These findings provide initial evidence that there may be inherent properties of common technology-mediated communication tools that may lead to momentary changes in affective experiences and make social connection more challenging. (shrink)

Recent advances in second-person neuroscience have allowed the underlying neural mechanisms involved in teaching-learning interactions to be better understood. Teaching is not merely a one-way transfer of information from teacher to student; it is a complex interaction that requires metacognitive and mentalizing skills to understand others’ intentions and integrate information regarding oneself and others. Physiotherapy involving therapists instructing patients on how to improve their motor skills is a clinical field in which teaching-learning interactions play a central role. Accumulating (...) evidence suggests that non-invasive brain stimulation modulates cognitive functions; however, NIBS approaches to teaching-learning interactions are yet to be utilized in rehabilitation. In this review, I evaluate the present research into NIBS and its role in enhancing metacognitive and mentalizing abilities; I then review hyperscanning studies of teaching-learning interactions and explore the potential clinical applications of NIBS in rehabilitation. Dual-brain stimulation using NIBS has been developed based on findings of brain-to-brain synchrony in hyperscanning studies, and it is delivered simultaneously to two individuals to increase inter-brain synchronized oscillations at the stimulated frequency. Artificial induction of brain-to-brain synchrony has the potential to promote instruction-based learning. The brain-to-brain interface, which induces inter-brain synchronization by adjusting the patient’s brain activity, using NIBS, to the therapist’s brain activity, could have a positive effect on both therapist-patient interactions and rehabilitation outcomes. NIBS based on second-person neuroscience has the potential to serve as a useful addition to the current neuroscientific methods used in complementary interventions for rehabilitation. (shrink)

The present paper focuses on the phenomenon of normativity and genericity in language and cognition. More specifically, it investigates the use of normative generics, which are generalizations that state an ideal norm for a given category, in the context of norm breaching in parent-child interactions in English. This issue is researched by means of a specially designed questionnaire including 8 norm breaching parent-child interactions, which has been completed online by ca. 70 English-speaking female respondents. The paper uses qualitative (...) and quantitative methods to address two specific research issues. First, it compares the frequency of use of normative generics in norm breaching situations vis-à-vis the use of other types of normative linguistic expressions. Second, it analyses selected factors that are believed to favour the use of normative generics, including interactive openness of a given situation, norm salience, and perceived norm importance. Moreover, the paper sketches an explanatory model of normative generics that draws upon insights from the Conceptual Metonymy Theory, Construction Grammar, and Dual System Theory. (shrink)

Modern social and scientific-technological progress have resulted in an unprecedented acceleration of rates of change in all the principal elements of the system comprising the material life of society: production, social relationships, the geographic environment, population, and others. This made more obvious the complex interrelationship among these elements and the need to coordinate them rationally within the framework of the single system of mutual determination of various natural and social factors, any disruption of the stability and integrity of which is (...) pregnant with exceedingly serious consequences to human existence. (shrink)

This study tests an instructional model designed to empower students in an early childhood classroom as emerging digital storytellers. Educators can use digital storytelling to support students’ learning by encouraging them to organize and express their ideas and knowledge in an individual and meaningful way while developing voice and facility in child-computer interactions. This work also helps develop traditional communication skills, fosters collaboration, and strengthens emergent literacy practices. Students may develop enhanced communications skills by learning to organize their ideas, (...) ask questions, express opinions, and construct narratives as they interact with others and computers in the creation of digital stories. The “Emerging Digital Storytellers” instructional model focuses on social-emotional development and finding student voice through writing and digital content construction in the early childhood educational context. (shrink)

This study examines interactional sequences in which students make assertions about topic-relevant matters in classroom interactions. Using a Conversation Analytical approach, I show how the students’ knowledge claims lead to negotiations of sequential and epistemic rights to make such claims. Through these negotiations, the students upgrade their epistemic stance by repeating or backing their claims with accounts and providing evidence of them. The teachers’ acceptance or rejection of the students’ initiatives displays an orientation to the sequential and topical relevance (...) of the information provided by the students. This study contributes to a better understanding of student initiatives in the classroom, a topic that until now has received scarce attention. Additionally, it contributes knowledge about the negotiation of epistemic authority in relation to assertions and their responses, which may have more general implications for the study of talk-in-interaction. (shrink)

An experiment by Proietti et al. purporting to instantiate the ‘Wigner’s Friend’ thought experiment is discussed. It is pointed out that the stated implications of the experiment regarding the alleged irreconcilability of facts attributed to different observers warrant critical review. In particular, violation of a Clauser–Horne–Shimony inequality by the experimental data actually shows that the attribution of measurement outcomes to the “Friends” is erroneous. An elementary but often overlooked result regarding improper mixtures is adduced in support of this assessment, and (...) a basic logical error in the analysis leading to the authors’ ontological claims that different observers are subject to irreconcilable ‘facts’ is identified. A counterexample is provided which refutes the popular notion that quantum theory leads to ‘relative facts’ that never manifest as empirical inconsistencies. It is further noted that under an assumption of unbroken unitarity, no measurement correlation can ever yield an outcome, since all systems remain in improper mixtures, and attributing a definite but unknown outcome contradicts their composite pure state. It is pointed out that there already exists a solution to this conundrum in the form of an alternative formulation of quantum theory, which accounts for the data showing that no outcomes occurred at the interior entangled photon level and also predicts that outcomes can and do occur at the exterior “super-observer” level in this type of experiment. (shrink)

Although interactions of proteins with glycosaminoglycans (GAGs), such as heparin and heparan sulphate, are of great biological importance, structural requirements for protein‐GAG binding have not been well‐characterised. Ionic interactions are important in promoting protein‐GAG binding. Polyelectrolyte theory suggests that much of the free energy of binding comes from entropically favourable release of cations from GAG chains. Despite their identical charges, arginine residues bind more tightly to GAGs than lysine residues. The spacing of these residues may determine protein‐GAG affinity (...) and specificity. Consensus sequences such as XBBBXXBX, XBBXBX and a critical 20 Å spacing of basic residues are found in some protein sites that bind GAG. A new consensus sequence TXXBXXTBXXXTBB is described, where turns bring basic interacting amino acid residues into proximity. Clearly, protein‐GAG interactions play a prominent role in cell‐cell interaction and cell growth. Pathogens including virus particles might target GAG‐binding sites in envelope proteins leading to infection. BioEssays 20:156–167, 1998. © 1998 John Wiley & Sons, Inc. (shrink)

This paper examines the emotional processes in Machiavellian leadership. The leadership literature portrays Machiavellians as ‘dark’ individuals that engage in unethical actions, causing employee dissatisfaction, distress, emotional exhaustion and high turnover. However, research has seldom questioned the processes behind these unethical and negative outcomes. This study explores Machiavellian emotional processes at multiple levels—within-persons and relational levels (between-persons and interpersonal interactions in organisations). In this study, emotions and leadership are not explored in isolation but as social processes that occur in (...) relationships between leaders and employees in evolving organisational settings. This study draws on 20 participants from four large multi-national construction firms in Sri Lanka. Open-ended semi-structured interviews were conducted to explore the emotions of Machiavellians in organisations. The findings suggest that Machiavellianism influences leader and employee emotional processes. Furthermore, the emotional processes, influenced by Machiavellianism, appear to facilitate the development of leader and employee relationships and emotional experiences at within-persons and relational levels in organisations. (shrink)

Despite intensive debates regarding action imitation and sentence imitation, few studies have examined their relationship. In this paper, we argue that the mechanism of action imitation is necessary and in some cases sufficient to describe sentence imitation. We first develop a framework for action imitation in which key ideas of Hurley’s shared circuits model are integrated with Wolpert et al.’s motor selection mechanism and its extensions. We then explain how this action-based framework clarifies sentence imitation without a language-specific faculty. Finally, (...) we discuss the empirical support for and philosophical significance of this perspective. (shrink)