Results for 'Immune Self'

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  1.  27
    The Immune Self: Theory or Metaphor?Alfred I. Tauber - 1994 - Cambridge University Press.
    This is one of the first books in a new series that will publish the very best work in the philosophy of biology. The series will be non-sectarian in character, will extend across the broadest range of topics, and will be genuinely interdisciplinary. The Immune Self is a critical study of immunology from its origins at the end of the nineteenth century to its contemporary formulation. The book offers the first extended philosophical critique of immunology, in which the (...)
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  2.  65
    From the immune self to moral agency. Comments.Alfred I. Tauber - 2012 - Avant: Trends in Interdisciplinary Studies 3 (1):101-105.
    Author comments on the changes in the philosophy of immunology that have occurred since the publication of his book The Immune Self: Theory or Metaphor?, as well as on the dangers, misunderstandings and expectations in this area. Finally, he presents his account of moral agency in the context of his own works discussing this question.
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  3.  16
    The immune self: a selectionist theory of recognition, learning, and remembering within the immune system.Richard L. Kradin - 1994 - Perspectives in Biology and Medicine 38 (4):605-623.
  4.  12
    The essence of immunity--self-nonself discrimination.B. Plytycz & R. Seljelid - 2000 - Dialogue and Universalism 10 (11).
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  5.  21
    The Immune Self[REVIEW]David L. Hull - 1997 - International Studies in Philosophy 29 (4):145-146.
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  6. Alfred Tauber, The Immune Self Theory or Metaphor? Reviewed by.Howard Schweber - 1995 - Philosophy in Review 15 (3):216-218.
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  7. Immune system, immune self. Introduction.Bartłomiej Świątczak - 2012 - Avant: Trends in Interdisciplinary Studies 3 (1):12-18.
    The idea that the immune system distinguishes between self and non-self was one of the central assumptions of immunology in the second half of 20 th century. This idea influenced experimental design and data interpretation. However, in the face of new evidence there is a need for a new conceptual framework in immunology.
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  8.  1
    Alfred I. Tauber, The Immune Self: Theory or Metaphor? Cambridge Studies in Philosophy and Biology. Cambridge: Cambridge University Press, 1994. Pp. x + 354. ISBN 0-521-46188-X. £37.50, $59.95. [REVIEW]Mark Jackson - 1995 - British Journal for the History of Science 28 (4):489-490.
  9.  28
    The elusive immune self: a case of category errors.Alfred I. Tauber - 1999 - Perspectives in Biology and Medicine 42 (4):459-474.
  10. Self-reference and schizophrenia: A cognitive model of immunity to error through misidentification.Shaun Gallagher - 2000 - In Dan Zahavi, Exploring the Self: Philosophical and Psychopathological Perspectives on Self-experience. Amsterdam: John Benjamins. pp. 203--239.
  11.  93
    Frank Macfarlane Burnet and the immune self.Alfred I. Tauber & Scott H. Podolsky - 1994 - Journal of the History of Biology 27 (3):531-573.
  12.  39
    Self-consciousness and the double immunity.Andrea Christo Fidou - 2000 - Philosophy 75:539.
    It is accepted that first-person thoughts are immune to error through misidentification. I argue that there is also immunity to error through misascription, failure to recognise which has resulted in mistaken claims that first-person thoughts involving the self-ascription of bodily states are, at best, circumstantially immune to error through misidentification relative to ‘I’ and, at worst, subject to error. Central to my thesis is that, first, ‘I’ is immune to error through misidentification absolutely, and that if (...)
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  13.  47
    (1 other version)Immunity to error through misidentification and the trilemma about the self.Annalisa Coliva - unknown
    The thesis addresses the issues of error through misidentification and immunity to error through misidentification in relation to the problem of the first person. First, it provides an explanation of error through misidentification. Secondly, it shows that there are two possible ways of understanding immunity to error through misidentification. It is then argued that the first understanding of immunity to error through misidentification leads to what is labelled "the trilemma about the self". That is to say, either we provide (...)
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  14. Self-Defence and the Principle of Non-Combatant Immunity.Helen Frowe - 2011 - Journal of Moral Philosophy 8 (4):530-546.
    The reductivist view of war holds that the moral rules of killing in war can be reduced to the moral rules that govern killing between individuals. Noam Zohar objects to reductivism on the grounds that the account of individual self-defence that best supports the rules of war will inadvertently sanction terrorist killings of non-combatants. I argue that even an extended account of self-defence—that is, an account that permits killing at least some innocent people to save one's own life—can (...)
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  15. Self-consciousness and the double immunity.Andrea Christofidou - 2000 - Philosophy 75 (294):539-570.
    It is accepted that first-person thoughts are immune to error through misidentification. I argue that there is also immunity to error through misascription, failure to recognise which has resulted in mistaken claims that first-person thoughts involving the self-ascription of bodily states are, at best, circumstantially immune to error through misidentification relative to.
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  16.  51
    The Self File and Immunity to Error Through Misidentification.Manuel García-Carpintero - 2013 - Disputatio 5 (36):191-206.
    Recanati’s (2007, 2009) argues for a Lewisian subjectless view of the content of “implicit” de se thought, on the basis that we can thus better explain the phenomenon of immunity to error through misidentification. The paper argues that this is not the case, and suggests that such a view is in tension with Recanati’s mental files approach to de re thought in general and the SELF concept in particular.
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  17.  82
    Immunity and Self-Awareness.Max Seeger - 2015 - Philosophers' Imprint 15.
    Three pathologies of alienation have been claimed to refute the philosophical thesis that introspection-based self-ascriptions of mental states are immune to error through misidentification. In this paper, I show that this critique of the Immunity Thesis is misguided; the cases of alienation either are not self-ascriptions or do not involve misidentification. Rather, these cases undermine a widely assumed explanation of immunity, which is based on the idea that self-ascriptions of mental states are identification-free. I argue that, (...)
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  18. Self-Consciousness and Immunity.Timothy Lane & Caleb Liang - 2011 - Journal of Philosophy 108 (2):78-99.
    Sydney Shoemaker, developing an idea of Wittgenstein’s, argues that we are immune to error through misidentification relative to the first-person pronoun. Although we might be liable to error when “I” (or its cognates) is used as an object, we are immune to error when “I” is used as a subject (as when one says, “I have a toothache”). Shoemaker claims that the relationship between “I” as-subject and the mental states of which it is introspectively aware is tautological: when, (...)
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  19.  35
    Immunity to error through misidentification and the functionalist, self-reflexive account of episodic memory.Steven James - 2021 - Estudios de Filosofía (Universidad de Antioquia) 64:189-200.
    Fernández offers an account of the nature of episodic memory that marries two core ideas: role-functionalism about episodic memory, and self-reflexive mnemonic content. One payoff of this view is that episodic memory judgments are immune to error through misidentification. Fernández takes this to reveal something important about the nature of one’s self-awareness in memory and our first-person conception of ourselves. However, once one sees why such judgments are immune in this way, according to the proposed account, (...)
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  20.  91
    Paradigms in immunology and modern, post-modern, post-post-modern, _ philosophy. A review of Alfred I. Tauber, the immune self: Theory or metaphor? [REVIEW]Henri Atlan - 1998 - Biology and Philosophy 13 (1):125-131.
  21.  52
    Facing the mirror: A relativist account of immune nonconceptual self-representations.Jérémie Lafraire - 2017 - Philosophical Psychology 30 (1-2):140-160.
    There is a consensus among philosophers that some “I”-thoughts are immune to error through misidentification. In some recent papers, this property has been formulated in the following deflationist way: an “I”-thought is immune to error through misidentification when it can misrepresent the mental or bodily property self-ascribed but cannot misrepresent the subject possessing that property. However, it has been put forward that the range of mental and bodily states that are immune in that limited sense cannot (...)
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  22. Memory and self-consciousness: immunity to error through misidentification.Andy Hamilton - 2009 - Synthese 171 (3):409-417.
    In The Blue Book, Wittgenstein defined a category of uses of “I” which he termed “I”-as-subject, contrasting them with “I”-as-object uses. The hallmark of this category is immunity to error through misidentification (IEM). This article extends Wittgenstein’s characterisation to the case of memory-judgments, discusses the significance of IEM for self-consciousness—developing the idea that having a first-person thought involves thinking about oneself in a distinctive way in which one cannot think of anyone or anything else—and refutes a common objection to (...)
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  23.  49
    The holobiont self: understanding immunity in context.Tamar Schneider - 2021 - History and Philosophy of the Life Sciences 43 (3):1-23.
    Both concepts of the holobiont and the immune system are at the heart of an ongoing scientific and philosophical examination concerning questions of the organism’s individuality and identity as well as the relations between organisms and their environment. Examining the holobiont, the question of boundaries and individuality is challenging because it is both an assemblage of organisms with physiological cohesive aspects. I discuss the concept of immunity and the immune system function from the holobiont perspective. Because of the (...)
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  24.  17
    Immunity: The Evolution of an Idea.Alfred I. Tauber - 2017 - New York, US: Oup Usa.
    In Immunity, Alfred Tauber sets forth a new theory of immunology that rejects the common principle of self and non-self, and the immune system's role as a protector of the self from external threats. Rather than serving to defend an independent entity, he argues, immunity participates in a large, complex eco-system of porous and flexible boundaries. Tauber's new approach to immunology necessitates a new biology in which symbiosis is the rule, not the exception.
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  25.  64
    Immunity to error through misidentification in observer memories: A moderate separatist account.Denis Perrin & Christopher Jude McCarroll - 2023 - Philosophy and Phenomenological Research 106 (2):299-323.
    Judgments based on episodic memory are often thought to be immune to errors of misidentification (IEM). Yet there is a certain category of episodic memories, viz. observer memories, that seems to threaten IEM. In the resulting debate, some say that observer memories are a threat to the IEM enjoyed by episodic memory (Michaelian, 2021); others say that they pose no such threat (Fernández, 2021; Lin, 2020). In this paper, we argue for a middle way. First, we frame the debate, (...)
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  26. Dismantling the Self/Other Dichotomy in Science: Towards a Feminist Model of the Immune System.Lisa Weasel - 2001 - Hypatia 16 (1):27-44.
    Despite the development of a vast body of literature pertaining to feminism and science, examples of how feminist phifosophies might be applied to scientific theories and practice have been limited. Moreover, most scientists remain unfamiliar with how feminism pertains to their work. Using the example of the immune system, this paper applies three feminist epistemologies feminist empiricism, feminist standpoint theory, and feminist postmodernismtoassess competingchims of immune function within a feminist context.
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  27.  58
    Is conscious thought immune to error through misidentification?Manuel García-Carpintero - forthcoming - Philosophical Psychology.
    Wittgenstein distinguished between two uses of “I”, one “as object” and the other “as subject”, a distinction that Shoemaker elucidated in terms of a notion of immunity to error through misidentification (“IEM”); first-personal claims are IEM in the use “as subject”, but not in the other use. Shoemaker argued that memory judgments based on “personal”, episodic memory are not strictly speaking IEM; Gareth Evans disputed this. Similar issues have been debated regarding self-ascriptions of conscious thoughts based on first-personal awareness, (...)
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  28.  42
    Adult neural stem cells: Long‐term self‐renewal, replenishment by the immune system, or both?Barbara S. Beltz, Emily L. Cockey, Jingjing Li, Jody F. Platto, Kristina A. Ramos & Jeanne L. Benton - 2015 - Bioessays 37 (5):495-501.
    The current model of adult neurogenesis in mammals suggests that adult‐born neurons are generated by stem cells that undergo long‐term self‐renewal, and that a lifetime supply of stem cells resides in the brain. In contrast, it has recently been demonstrated that adult‐born neurons in crayfish are generated by precursors originating in the immune system. This is particularly interesting because studies done many years ago suggest that a similar mechanism might exist in rodents and humans, with bone marrow providing (...)
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  29.  46
    Understanding Immune Tolerance of Cancer: Re‐Purposing Insights from Fetal Allografts and Microbes.Megan B. Barnet, Prunella Blinman, Wendy Cooper, Michael J. Boyer, Steven Kao & Christopher C. Goodnow - 2018 - Bioessays 40 (8):1800050.
    Cancer cells seem to exploit mechanisms that evolve as part of physiological tolerance, which is a complementary and often beneficial form of defense. The study of physiological systems of tolerance can therefore provide insights into the development of a state of host tolerance of cancer, and how to break it. Analysis of these models has the potential to improve our understanding of existing immunological therapeutic targets, and help to identify future targets and rational therapeutic combinations. The treatment of cancer with (...)
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  30.  70
    Immunity in Context.Alfred I. Tauber - 2016 - Theoria: Revista de Teoría, Historia y Fundamentos de la Ciencia 31 (2):207-224.
    According to immunology’s prevailing paradigm, immunity is based on self/nonself discrimination and thus requires a construction of identity. Two orientations vie for dominance: The original conception, conceived in the context of infectious diseases, regards the organism as insular and autonomous, an entity that requires defense of its borders. An alternate view places the organism firmly in its environment in which both benign and onerous encounters occur. On this latter relational account, active tolerance allows for cooperative relationships with other organisms (...)
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  31. Immunity, thought insertion, and the first-person concept.Michele Palmira - 2020 - Philosophical Studies 177 (12):3833-3860.
    In this paper I aim to illuminate the significance of thought insertion for debates about the first-person concept. My starting point is the often-voiced contention that thought insertion might challenge the thesis that introspection-based self-ascriptions of psychological properties are immune to error through misidentification relative to the first-person concept. In the first part of the paper I explain what a thought insertion-based counterexample to this immunity thesis should be like. I then argue that various thought insertion-involving scenarios do (...)
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  32.  15
    Women amid the COVID-19 pandemic: Self-protection through the behavioral immune system.Alfonso Troisi - 2022 - Behavioral and Brain Sciences 45.
    Studies of the activation of the behavioral immune system triggered by the coronavirus disease-2019 pandemic have demonstrated that evolutionary explanations of individual differences in self-protection should not be based only on parental investment and sexual selection theory. An evolutionary model must also incorporate individual differences that arise within each sex as a result of life history strategies and attachment patterns.
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  33.  46
    Artificial Immune System–Negative Selection Classification Algorithm (NSCA) for Four Class Electroencephalogram (EEG) Signals.Nasir Rashid, Javaid Iqbal, Fahad Mahmood, Anam Abid, Umar S. Khan & Mohsin I. Tiwana - 2018 - Frontiers in Human Neuroscience 12:424534.
    Artificial Immune Systems (AIS) are intelligent algorithms derived on the principles inspired by human immune system. In this research work, electroencephalography (EEG) signals for four distinct motor movement of human limbs are detected and classified using Negative Selection Classification Algorithm (NSCA). For this study, a widely studied open source EEG signal database (BCI IV - Graz dataset 2a, comprising 9 subjects) has been used. Mel Frequency Cepstral Coefficients (MFCCs) are extracted as selected feature from recorded EEG signals. Dimensionality (...)
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  34.  82
    Immune balance: The development of the idea and its applications.Bartlomiej Swiatczak - 2014 - Journal of the History of Biology 47 (3):411-442.
    It has long been taken for granted that the immune system’s capacity to protect an individual from infection and disease depends on the power of the system to distinguish between self and nonself. However, accumulating data have undermined this fundamental concept. Evidence against the self/nonself discrimination model left researchers in need of a new overarching framework able to capture the immune system’s reactivity. Here, I highlight that along with the self/nonself model, another powerful representation of (...)
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  35. Psychological immunity, bodily ownership, and vice versa.Carlota Serrahima - forthcoming - Philosophical Psychology.
    This paper presents a view on bodily IEM by describing, first, the structure that grounds need to have in order to yield IEM judgments, and then arguing that somatosensation has this structure. I make my case by presenting an analysis of the sense of bodily ownership. According to this analysis, there is a substantive explanatory relationship between bodily self-consciousness and psychological self-consciousness. I argue that one central virtue of this approach to bodily self-consciousness is that, not only (...)
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  36.  41
    Immunity and Negation: On Possible Developments of the Theses Outlined in Roberto Esposito's Immunitas.Massimo Donà, Loredana Comparone & Andrea Righi - 2006 - Diacritics 36 (2):57-69.
    What is the relation of risk to negativity? Is it possible to think a notion of the negative that doesn't exclude the other via inclusion? These two questions are at the heart of Massimo Donà's discussion of immunity. Drawing on Roberto Esposito's genealogy of immunity in community, Donà shows how immunity depends upon a paradox of separation that brings the common and the immune closer together. After sketching the relation of immunity to the notion of polemos, Donà argues that (...)
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  37.  36
    Innate immunity against molecular mimicry: Examining galectin‐mediated antimicrobial activity.Connie M. Arthur, Seema R. Patel, Amanda Mener, Nourine A. Kamili, Ross M. Fasano, Erin Meyer, Annie M. Winkler, Martha Sola-Visner, Cassandra D. Josephson & Sean R. Stowell - 2015 - Bioessays 37 (12):1327-1337.
    Adaptive immunity provides the unique ability to respond to a nearly infinite range of antigenic determinants. Given the inherent plasticity of the adaptive immune system, a series of tolerance mechanisms exist to reduce reactivity toward self. While this reduces the probability of autoimmunity, it also creates an important gap in adaptive immunity: the ability to recognize microbes that look like self. As a variety of microbes decorate themselves in self‐like carbohydrate antigens and tolerance reduces the ability (...)
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  38.  55
    Bodily immunity to error.Frédérique De Vignemont - unknown
    Are bodily self-ascriptions immune to error through misidentification? According to the Inside mode view, one cannot be mistaken about whose body part it is when experiencing them from the inside. Here I shall consider two possible objections to bodily immunity. On the one hand, I shall briefly envisage two cases of misidentification: somatoparaphrenia and the Rubber Hand illusion. I shall show that none of them challenges the immunity principle. On the other hand, I shall highlight a more serious (...)
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  39. (1 other version)Self-consciousness.José Luis Bermúdez - 2007 - In Max Velmans & Susan Schneider, The Blackwell Companion to Consciousness. New York: Wiley-Blackwell. pp. 472–483.
    Self‐consciousness is a topic located at the intersection of a range of different philosophical concerns. One set of concerns is metaphysical. Another is epistemological. When discussing the phenomenon of consciousness in general, philosophers generally think it possible to give an account of consciousness that is independent of how one understands the objects, properties, and events of which one is conscious. Self‐consciousness is important because of the role it plays in the cognitive economy. Self‐consciousness can be understood either (...)
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  40. Immunity to error through misidentification: What it is and where it comes from.François Recanati - 2012 - In Simon Prosser & François Recanati, Immunity to error through misidentification. Cambridge University Press. pp. 180--201.
    I argue that immunity to error through misidentification primarily characterizes thoughts that are 'implicitly' de se, as opposed to thoughts that involve an explicit self-identification. Thoughts that are implicitly de se involve no reference to the self at the level of content: what makes them de se is simply the fact that the content of the thought is evaluated with respect to the thinking subject. Or, to put it in familiar terms : the content of the thought is (...)
     
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  41. Which immunity to error?Joel Smith - 2006 - Philosophical Studies 130 (2):273-83.
    A self-ascription is a thought or sentence in which a predicate is self-consciously ascribed to oneself. Self-ascriptions are best expressed using the first-person pronoun. Mental self-ascriptions are ascriptions to oneself of mental predicates (predicates that designate mental properties), non-mental self-ascriptions are ascriptions to oneself of non-mental predicates (predicates that designate non-mental properties). It is often claimed that there is a range of self-ascriptions that are immune to error through misidentification relative to the first-person (...)
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  42.  75
    Immunity, nobility, and the edict of Paris.Alexander Callander Murray - 1994 - Speculum 69 (1):18-39.
    Immunity was an institution of Roman and Frankish public law that conferred exemption from various kinds of state obligations. In Roman law, immunity might be granted to an individual, group, or community by the public authority, whether the Roman state itself or one of its constituent self-regulating bodies. It was not an institution with a fixed content; terms varied according to the discretion and powers of the grantor and the system of obligations from which relief was sought. Exemption might (...)
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  43.  19
    Innate immunity and its evasion and suppression by hymenopteran endoparasitoids.Otto Schmidt, Uli Theopold & Mike Strand - 2001 - Bioessays 23 (4):344-351.
    Recent studies suggest that insects use pattern recognition molecules to distinguish prokaryotic pathogens and fungi from “self” structures. Less understood is how the innate immune system of insects recognizes endoparasitic Hymenoptera and other eukaryotic invaders as foreign. Here we discuss candidate recognition factors and the strategies used by parasitoids to overcome host defense responses. We suggest that host–parasitoid systems are important experimental models for studying how the innate immune system of insects recognizes foreign invaders that are phylogenetically (...)
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  44. Immunity to error through misidentification: What it is and where it comes from.François Recanati - 2012 - In Simon Prosser & François Recanati, Immunity to error through misidentification. Cambridge University Press. pp. 180--201.
    I argue that immunity to error through misidentification primarily characterizes thoughts that are 'implicitly' de se, as opposed to thoughts that involve an explicit self-identification. Thoughts that are implicitly de se involve no reference to the self at the level of content: what makes them de se is simply the fact that the content of the thought is evaluated with respect to the thinking subject. Or, to put it in familiar terms : the content of the thought is (...)
     
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  45. Three Questions About Immunity to Error Through Misidentification.Giovanni Merlo - 2017 - Erkenntnis 82 (3):603-623.
    It has been observed that, unlike other kinds of singular judgments, mental self-ascriptions are immune to error through misidentification: they may go wrong, but not as a result of mistaking someone else’s mental states for one’s own. Although recent years have witnessed increasing interest in this phenomenon, three basic questions about it remain without a satisfactory answer: what is exactly an error through misidentification? What does immunity to such errors consist in? And what does it take to explain (...)
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  46.  27
    TGF‐β Control of Adaptive Immune Tolerance: A Break From Treg Cells.Ming Liu & Shun Li - 2018 - Bioessays 40 (11):1800063.
    The vertebrate adaptive immune system has well defined functions in maintaining tolerance to self‐tissues. Suppression of autoreactive T cells is dependent on the regulatory cytokine transforming growth factor‐β (TGF‐β) and regulatory T (Treg) cells, a distinct T cell lineage specified by the transcription factor Foxp3. Although TGF‐β promotes thymic Treg (tTreg) cell development by repressing T cell clonal deletion and peripheral Treg cell differentiation by inducing Foxp3 expression, a recent study shows that TGF‐β suppresses autoreactive T cells independent (...)
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  47.  47
    Self-protection as an adaptive female strategy.Joyce F. Benenson, Christine E. Webb & Richard W. Wrangham - 2022 - Behavioral and Brain Sciences 45:e128.
    Many male traits are well explained by sexual selection theory as adaptations to mating competition and mate choice, whereas no unifying theory explains traits expressed more in females. Anne Campbell's “staying alive” theory proposed that human females produce stronger self-protective reactions than males to aggressive threats because self-protection tends to have higher fitness value for females than males. We examined whether Campbell's theory has more general applicability by considering whether human females respond with greater self-protectiveness than males (...)
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  48. A self for the body.Frédérique de Vignemont - 2011 - Metaphilosophy 42 (3):230-247.
    Abstract: What grounds the experience of our body as our own? Can we rationally doubt that this is our own body when we feel sensations in it? This article shows how recent empirical evidence can shed light on issues on the body and the self, such as the grounds of the sense of body ownership and the immunity to error through misidentification of bodily self-ascriptions. In particular, it discusses how bodily illusions (e.g., the Rubber Hand Illusion), bodily disruptions (...)
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  49. De se thoughts and immunity to error through misidentification.Manuel García-Carpintero - 2018 - Synthese 195 (8):3311-3333.
    I discuss an aspect of the relation between accounts of de se thought and the phenomenon of immunity to error through misidentification. I will argue that a deflationary account of the latter—the Simple Account, due to Evans —will not do; a more robust one based on an account of de se thoughts is required. I will then sketch such an alternative account, based on a more general view on singular thoughts, and show how it can deal with the problems I (...)
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  50.  71
    Towards an ecological view of immunity.Swiatczak Bartlomiej - 2017 - Studies in History and Philosophy of Science Part C: Studies in History and Philosophy of Biological and Biomedical Sciences 63:85-88.
    The immune system does not just fight pathogens but also engages in interactions with beneficial microbes and non-immune cells of the body to harmonize their behavior by means of cytokines, antibodies and effector cells (Dinarello, 2007; Moticka, 2015, pp. 217e226, 261e267). However, the importance of these “housekeeping” functions has not been fully appreciated (Cohen, 2000). In his new book Immunity: The Evolution of an Idea Alfred I. Tauber traces the history of fundamental ideas in immunology and refers to (...)
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