1-2. Sōkō -- 3. Katō Hiroyuki kōen zenshū ; Shizen to rinri ; Kokka no tōchiken ; Sekininron ; Jinsei no shizen to waga kuni no zento.

BackgroundThe evaluation of pain remains one of the most difficult challenges that healthcare practitioners face. Chronic pain appears to affect more than 35% of the population in the West, and indeed, pain is the most common reason patients seek medical care. Despite its ubiquity, studies in the last decades reveal that many patients feel their pain is dismissed by healthcare practitioners and that, as a result, they are denied proper medical care. Buchman, Ho, and Goldberg (J Bioethic Inq 14:31-42, 2017) (...) point to this phenomenon as a form of “epistemic injustice”: an unfair and harmful downgrading of credibility affecting some individuals and groups, which prevents them from receiving appropriate and beneficial medical care.MethodsBy exploring the existing literature on this downgrading of patients’ credibility written by healthcare professionals and scholars in medical humanities, I identify and examine the reasons patients are often not believed about their pain and why healthcare is too-often unhelpful or hurtful to people presenting with chronic pain. I also explore to what extent it is possible to forge an alternative epistemological model.ResultsI suggest that most of the causes of this downgrading of patient’s credibility result from either the difficulty in communicating pain or the widespread belief that pathology is always the result of objective tissue damage. I examine whether pain has to be effectively communicated and have an objective cause in order for it to be deemed credible. In the end, I argue that in the case of pain, both communication and objectivity are highly problematic.ConclusionsI conclude by suggesting that, although alternative epistemological models might be impossible to build, believing patients has both moral and clinical benefits, and this warrants further research. (shrink)

At the outbreak of the Covid-19 pandemic, several countries declared “states of exception,” that is, authorized legal devices that, in the face of circumstances deemed catastrophic, permit the implementation of extraordinary measures and the temporary suspension of some rights in order to restore the previous state of affairs as soon as possible. This paper offers a comparative textual analysis of the different states of exception declared in the USA, France, and Spain. I argue that these texts constitute a privileged site (...) to explore how prevalent global political logics and mainstream discourses on illness are interwoven. Regarding the global political logics in play, I hold that these declarations constitute an instantiation of democracy’s autoimmune character; it attacks itself in order to protect itself. Regarding mainstream discourses on illness, I explore how illness is regarded as a threat to one’s self (by something seemingly other) and the notion that therapy must consist of securing the self’s triumph over anything seemingly other. This twofold analysis reveals that an aporetic dialectic between self and other—as regards politics and illness—operates in these declarations, most likely because it is, in fact, one and the same dialectic, upon which Western epistemology rests. Furthermore, I suggest that these texts reflect and promote these dominant logics, contributing to shape human relationships around the globe in a certain dangerous way. (shrink)

In this paper we claim educational leadership as an autonomous discipline whose goals and strategies should not mirror those typical of business and political leadership. In order to define the aims proper to educational leadership we question three common assumptions of what it is supposed to carry out. First, we turn to Hannah Arendt and her contemporary critics to maintain that education aims at opening up exceptions within the normal course of events rather than simply preserving it. This way, education (...) is not reduced to an instrument at the service of the reinforcement of a given social and economic system. This leads us to ask what should exactly educational leadership oppose by means of these exceptions. According to Tyson E. Lewis’s wise application to education of Giorgio Agamben’s ontology of impotentiality, the apparently reasonable idea that education must help the subject to develop his potentials is precisely an instrumentalization of education which brings about a desubjectification of the learner. Education should actually make the pupil aware of his right not to carry his potentiality to its actualization and dwell instead in a state of impotentiality. Third and last, we complicate this picture by alluding to Zygmunt Bauman’s critique of the rejection of Western individuals to realize certain possibilities, which they deem too costly. By analysing in conjunction Agamben’s encouragement to suspend one’s potential and Bauman’s insistence on the need of not suspending it, we conclude by defining what, in our opinion, defines the raison d’être of educational leadership. (shrink)

This paper analyses, both historically and systematically, the underlying causes of specific characteristics of globalism and nationalism in Japan focusing on an ideological moral education that lies at the heart of the problems of Japanese education. The analysis highlights two issues. (1) There is no real globalism in modern Japan. Certainly, the globalization of industry, government, and academia is now loudly proclaimed in Japan. However, in the name of globalization, English education is overemphasized. (2) There is no real nationalism in (...) modern Japan. Japan once had a nationalism centred on the emperor system from the Meiji era. However, after World War II, the emperor system in Japan was dismantled and a democratic Japanese Constitution was enacted under the influence of the Allied Powers. Furthermore, in the Basic Act on Education, the theory of ‘the perfection of personality’ based on Kant’s philosophy was transplanted. Education in post-war Japan developed based on a democratic constitution and the Basic Act on Education, which states that the purpose of education is ‘the perfection of personality’. This means that education has a strong moral flavour. Particularly at the stage of compulsory education in Japan, which is the foundation of national education, moral education is addressed through all educational activities at school. Therefore, the issues of globalism and nationalism in moral education, which this article deals with, belong directly to core problems of Japanese education. (shrink)

日本朱子学、日本陽明学、徂徠学、幕末思想など、代表的な思想家たちの歴史観/政治観を軸に近世を俯瞰する著者の代表研究。.

Actomyosin (actin‐myosin II complex)‐mediated contractile forces are central to the generation of multifaceted uni‐ and multi‐cellular material properties and dynamics such as cell division, migration, and tissue morphogenesis. In the present article, we summarize our recent researches addressing molecular mechanisms that ensure actomyosin‐mediated directional cell–cell junction remodeling, either shortening or extension, driving cell rearrangement for epithelial morphogenesis. Genetic perturbation clarified two points concerning cell–cell junction remodeling: an inhibitory mechanism against negative feedback in which actomyosin contractile forces, which are well known (...) to induce cell–cell junction shortening, can concomitantly alter actin dynamics, oppositely leading to perturbation of the shortening; and tricellular junctions as a point that organizes extension of new cell–cell junctions after shortening. These findings highlight the notion that cells develop underpinning mechanisms to transform the multi‐tasking property of actomyosin contractile forces into specific and proper cellular dynamics in space and time. (shrink)

We study the dynamics of a vortex in superfluid He4. This is carried out by deriving the effective Lagrangian for the center of the vortex by starting with the time-dependent Ginzburg-Landau formalism. From the resultant equation of motion for a vortex, we arrive at a novel aspect for the Magnus force which has long been known in fluid dynamics. This force has a geometric origin and is expected to occur in other form of condensates such as vortex excitations for quantum (...) Hall fluids or ferromagnets. We also consider the force of non geometric origin, the pinning force coming from the impurity. (shrink)

ABSTRACTIn the last decades, narrative theory has collaborated with sociology and anthropology of health to account for the importance that illness narratives hold for those who are or have been si...

Roberto Esposito (1998; 2002; 2008) examines how immunological apparatuses originally designed to protect communities end up undermining communities. This paper explores comparatively his view on the interplay between community and immunity with Giorgio Agamben’s and Jacques Derrida’s, although in their works these notions appear under other labels. Beyond pointing out their similarities, the paper concludes by analyzing what, in our view, constitute the raison d’être of their ultimate and irreconcilable differences: Agamben’s approach is _antinomic_, while Derrida’s is _aporetic_ and Esposito’s (...) is rather _dialectical_. (shrink)

Establishment of cell lineage identity from multipotent progenitors is controlled by cooperative actions of lineage‐specific and stably expressed transcription factors, combined with input from environmental signals. Lineage‐specific master transcription factors activate and repress gene expression by recruiting consistently expressed transcription factors and chromatin modifiers to their target loci. Recent technical advances in genome‐wide and multi‐omics analysis have shed light on unexpected mechanisms that underlie more complicated actions of transcription factors in cell fate decisions. In this review, we discuss functional dynamics (...) of stably expressed and continuously required factors, Notch and Runx family members, throughout developmental stages of early T cell development in the thymus. Pre‐ and post‐commitment stage‐specific transcription factors induce dynamic redeployment of Notch and Runx binding genomic regions. Thus, together with stage‐specific transcription factors, shared transcription factors across distinct developmental stages regulate acquisition of T lineage identity. (shrink)

This collection of classic works from the mid-nineteenth through mid-twentieth centuries was originally published under the auspices of the Royal Asiastic Society. Spanning over 100 years in oriental scholarship, primary texts include work by Frederic Rosen, W.F. Thompson, C. Edward Sachau, R.A. Nicholson, W.H.T. Gairdner, W.M. Miller, James Robson, and many others.

簡潔性、実用性に卓越したQuineの『方法』を詳説、それに基づきG ̈odelやChurchの定理を含む、標準的な論理学を厳密に展開する。また、認識論理学の「自然演繹法」化の、1つの可能性を提案する。更に、「超実数」の必要性を強調し、それにより種々のアポリア(パラドッ クス等)の解明を試みる。.

エンジニアの「知」は21世紀を拓けるか。モノを「つくる」とは、どういうことか。技術者の心に由来する「知」のありように迫る。技術における「知」の現代性を確認する。.

This paper studies a fundamental mechanism by which conflicts between arguments are drawn from sentiments regarding acceptability of the arguments. Given sets of arguments, an inverse abstract argumentation problem seeks attack relations between arguments such that acceptability semantics interprets each argument in the sets of arguments as being acceptable in each of the attack relations. It is an inverse problem of the traditional problem we refer to as the forward abstract argumentation problem. Given an attack relation, the forward abstract argumentation (...) problem seeks sets of arguments such that acceptability semantics interprets each argument in the sets of arguments as being acceptable in the attack relation. We give a probabilistic model of argumentation-theoretic inference. It is a generative model formalising the process by which acceptability semantics interprets acceptability of arguments in a given attack relation. We show that it gives a broad view of solutions to the forward and inverse abstract argumentation problems. Specifically, solutions to the inverse and forward abstract argumentation problems are shown to be equivalent to a maximum likelihood estimate and maximum likelihood prediction, respectively, which are both available with the generative model. In addition, they are shown to be special cases of the posterior distribution and the evidence, respectively, which are both obtained by probabilistic inference on the generative model. We report an experiment result and application example of the generative model in the inverse problems. (shrink)

Previous research found that application of eyeshadow on the upper eyelids induces overestimation of eye size. The present study examined whether this eyeshadow illusion is dependent on or independent of viewpoint. We created a three-dimensional model of a female face and manipulated the presence/absence of eyeshadow and face orientation around the axis of yaw (Experiment 1) or pitch (Experiment 2) rotation. Using the staircase method, we measured perceived eye size for each face stimulus. Results showed that the eyeshadow illusion occurred (...) regardless of face orientation around axes of both yaw and pitch rotations. Crucially, the illusion’s magnitude did not vary across face orientations; lack of interaction between the illusion’s magnitude and face orientation was confirmed by small values of Bayes factors. These findings ruled out the hypothesis that eyeshadow serves as a depth cue and leads to overestimation of eye size due to size-distance scaling. Alternatively, the present findings suggest that the eyeshadow illusion can be well explained by the assimilation between the eyes and eyeshadow, which also facilitates assimilation between the eyes and eyebrows. Practical implications and the present findings’ generalizability are also discussed. (shrink)

This article constructs a static model of information acquisition when the agent does not know exactly what pieces of information he is missing. A representation of preferences over information channels and menus of lotteries is shown by adapting the model of unforeseen contingencies by Dekel et al. (Econometrica 69:891–934, 2001; Econometrica 75:591–600, 2007), which is an extension of Kreps (Econometrica 47:565–576, 1979; Economic analysis of markets and games: essays in honor of Frank Hahn, 1992). Also, characterisation of informativeness of an (...) information channel analogous to the one by Blackwell (Ann Math Stud 24:265–272, 1953) is examined in conjunction with the preference for flexibility by applying the structure of Shapley value. (shrink)

Volume 6, Issue 3, September 2015, Page 292-309.