dai 1-kan. Ningen, kyōiku ga umarekawaru tame -- dai 2-kan. Ningen to no deai, kyōiku to no deai -- dai 3 kan. Ningenrashiku naru tedate -- dai 4-kan. Jinrui no kibō, osanago -- dai 5-kan. Shishū, ushinawareta kisetsu o motomete -- dai 6-kan. Aru mazushiki shōgai no kiroku -- [7] Kyōiku to kyōikugaku.

Master Sorai's Responsals was to eighteenth-century Japan what The Prince was to Renaissance Italy. Like Machiavelli, Ogyu Sorai was a humanist scholar who served a prince and drew on his experiences as a house philosopher and on his vast knowledge of history and political affairs in his work. In 1720, when he began to write the letters that comprise this text, the Tokugawa regime was more than a hundred years old and beset with grave administrative and fiscal problems, about which (...) Sorai had much to say.Samuel Yamashita's impressive translation of this work offers modern readers a rare glimpse of the prevailing political discourse of the day and the specific concepts that rulers had at their disposal as they struggled to manage their domains, find talented men for their bureaucracies, create new sources of revenue, and keep their subjects well fed and happy.Sorai himself, of course, is a presence in the text. He is by tunes earnest, frank, impatient, utterly confident, and occasionally condescending. Unlike his Renaissance counterpart, he is something of an optimist: he was convinced that the introduction of archaic Chinese culture and institutions to Japan would solve its myriad problems.Well-versed in Chinese history, philosophy, religion, medicine, and belles lettres, Sorai holds forth on everything from archaic Chinese divination to Sung poetry and prose. He offers advice on how to become a Confucian gentleman, how to learn to read classical Chinese, and which books to read and which to avoid. He even discusses his belief in a sentient, Chinese-style "heaven," a topic not well understood by modern scholars. Long regarded as one of Sorai's best works, Master Sorai's Reponsals bristles with the sharp and clear opinions of the most influential thinker of Tokugawa Japan. (shrink)

『日本唯物論史』などで知られるわが国の唯物論哲学の開拓者・永田廣志の生涯をまとめ、その理論活動の意義を解明。哲学研究者と在野の郷土史家との共同研究が生み出した成果。本邦初公開の貴重な資料や秘蔵写真も多 数紹介。.

哲学者・古在由重がひとりの同時代人として、戦争に突き進み拡大する戦中、そして平和と民主主義を希求する戦後のなかで、何を学び、考え、仲間たちとどう交遊・談話し、どう生き、闘ったか。膨大な「古在由重文庫」 (藤沢市湘南大庭市民図書館所蔵)―古在の蔵書・著作はもちろん、原稿メモ、講義テープ、日記・手帳、書簡、新聞スクラップなど―ならびに関係者の著作・文章を渉猟し、さらに多数の人々の聞き取りなど六年をかけて 取材・執筆し、時代に正面から立ち向かった哲学者の実像に迫る力作。.

現代を生き抜くための武器としての哲学を、西野カナ、ミスチル、いきものがかり等Jポップの歌詞を題材に、気鋭の哲学者が説く。.

In this paper, I will investigate Wittgenstein’s idea about the context-sensitivity of utterance. It is the idea that there is a big gap between understanding a sentence in the sense of knowing the idioms and discerning the grammar in it, and what is said by using it in a particular context. Although context-sensitivity in this moderate sense is a familiar idea in Wittgensteinian scholarship, it has mainly been studied as an idea in “Wittgenstein’s philosophy of language.” However, Wittgenstein’s interest in (...) language is always connected with his interest in the treatment of philosophical problems. Therefore, what is lacking in those preceding studies is the study of the relation between Wittgenstein’s engagement with the idea of context-sensitivity and his philosophical therapy. Therefore, I shall investigate that relation and show that Wittgenstein’s philosophical method cannot be intelligible without taking context-sensitivity into consideration and Wittgenstein’s focus on context is deeply connected with his method for treating philosophers’ “pictures.” Below, I will examine recent debates on grammar, and argue that the standard interpretation is untenable once proper consideration is given to context-sensitivity. Next, I will argue that context-sensitivity is important because it gives us a good grasp of the process of a philosopher’s being caught in a picture by citing the discussion about mental process and about the Augustinian picture and rule-following in Philosophical Investigations. Finally, I will talk about the significance of my interpretation for contemporary arguments about philosophical methods. (shrink)

The mitogenic action of cytokines such as epidermal growth factor (EGF)d̊ or platelet dericed growth factor (PDGF) involves the stimulation of a signal cascade controlled by a small G protein called Ras. Mutations of Ras can cause its constitutive activation and, as a consequence, bypass the regulation of cell growth by cytokines. Both growth factor‐induced and oncogenic activation of Ras involve the conversion of Ras from the GDP‐bound (D‐Ras) to the GTP‐bound (T‐Ras) forms. T‐Ras activates a network of protein kinases (...) including c‐Mos, c‐Raf‐1 and MAP kinase. Eventually the activation of MAP kinase leads to the activation of the elongation factor 4E and several transcription factors such as c‐Jun, c‐Myc and c‐Fos. There are several modulators of Ras activity, such as the GTPase activating proteins (GAP1 and NF1), which stimulate the coversion of T‐Ras to D‐Ras. A series of small NF1 fragments, which bind T‐Ras, as well as truncated forms or derivatives of c‐Raf‐1, c‐Jun and c‐Myc, are capable of blocking the T‐Ras‐activated mitogenesis in a competitive manner. These agents offer a unique opportunity to control the proliferation of T‐Ras‐associated tumors, which represent more than 30% of total human carcinomas. (shrink)

We investigate how weak square principles are denied by Chang’s Conjecture and its generalizations. Among other things we prove that Chang’s Conjecture does not imply the failure of \documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$${\square_{\omega_1, 2}}$$\end{document}, i.e. Chang’s Conjecture is consistent with \documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$${\square_{\omega_1, 2}}$$\end{document}.

Minami–Sakai :883–898, 2016) investigated the cofinal types of the Katětov and the Katětov–Blass orders on the family of all \ ideals. In this paper we discuss these orders on analytic P-ideals and Borel ideals. We prove the following:The family of all analytic P-ideals has the largest element with respect to the Katětov and the Katětov–Blass orders.The family of all Borel ideals is countably upward directed with respect to the Katětov and the Katětov–Blass orders. In the course of the proof of (...) the latter result, we also prove that for any analytic ideal \ there is a Borel ideal \ with \. (shrink)

Since the first half of the nineteenth century in which English was introduced as the language of higher education in India, the word and concept of “philosophy” has played an important role in Indian intellectual life. First the study of philosophy must have meant the study of Western philosophy in Indian universities, butlater various attempts were made to discover the Indian versions of philosophical traditions in Sanskrit literature. Today no one doubts that there has been a rich and very long (...) tradition of such intellectual activities as are fully compatible with what European philosophers have actually been doing. Nevertheless, it is sometimes very difficult to draw a strict line between philosophy and religion in Indian thought. The present study will focus on that passage of the Nyāyamañjarī by a Kashmirian Nyāya scholar Jayanta which deals with the justification of the authority of the Vedas and other religious scriptures. From the analysis of the passage we may detect that there are two different dimensions in his application of logic for this issue. On the one hand he appeals to logical thinking for the defence of the Vedic authority and tries to establish the proper proof. But on the other hand he seems to be conscious of the limitation of reasoning, for he refers to those thinkers without refuting them in the latter half of the passage, according to whom every religious scripture must be accepted as valid insofar as the path of reasoning and argumentation is taken. (shrink)

This study compared 30 older musicians and 30 age-matched non-musicians to investigate the association between lifelong musical instrument training and age-related cognitive decline and brain atrophy. Although previous research has demonstrated that young musicians have larger gray matter volume in the auditory-motor cortices and cerebellum than non-musicians, little is known about older musicians. Music imagery in young musicians is also known to share a neural underpinning [the supramarginal gyrus and cerebellum] with music performance. Thus, we hypothesized that older musicians would (...) show superiority to non-musicians in some of the abovementioned brain regions. Behavioral performance, GMV, and brain activity, including functional connectivity during melodic working memory tasks, were evaluated in both groups. Behaviorally, musicians exhibited a much higher tapping speed than non-musicians, and tapping speed was correlated with executive function in musicians. Structural analyses revealed larger GMVs in both sides of the cerebellum of musicians, and importantly, this was maintained until very old age. Task-related FC analyses revealed that musicians possessed greater cerebellar-hippocampal FC, which was correlated with tapping speed. Furthermore, musicians showed higher activation in the SMG during MWM tasks; this was correlated with earlier commencement of instrumental training. These results indicate advantages or heightened coupling in brain regions associated with music performance and imagery in musicians. We suggest that lifelong instrumental training highly predicts the structural maintenance of the cerebellum and related cognitive maintenance in old age. (shrink)

Rousseau a bien compris, mieux que ses contemporains peut-être, le paradoxe de la communication propre aux Lumières, prises entre le développement du savoir et la constitution d'une opinion publique. Avec l'accélération de la circulation des discours et des écrits, comment parler et agir philosophiquement sans se perdre? Comment concilier la culture du secret, issue de la tradition littéraire du libertinage érudit, et la publicité, qui ouvre de plus en plus grands les horizons de la sphère publique? Masano Yamashita examine (...) ici l'articulation entre les stratégies rhétoriques de l'adresse au lecteur chez Rousseau et sa conception proprement philosophique de la communication. Elle met en lumière l'originalité et la lucidité de Rousseau face aux difficultés liées à cette société de l'information d'Ancien Régime. Rousseau cherche les conditions de possibilité d'une parole émancipée et pleinement publique. Au moyen d'une philosophie incarnée mettant en scène une figure de lecteur, il met à l'épreuve l'idée d'un sujet universel, la constitution d'un espace public, le sens de l'exercice de la philosophie, les enjeux politiques et éthiques des actes de discours. La réception des textes et le rapport au public constituent ainsi pour Rousseau un enjeu philosophique. Entre exigence de transparence et désir d'expérimenter les diverses facettes du moi public, se dessine la conception originale que Rousseau se fait de l'homme des Lumières. Masano Yamashita montre que la réflexion de Rousseau sur les manières de vivre dans un espace public, social comme littéraire, débouche sur une véritable vie philosophique. (shrink)

In this paper, we study the relationship among classical logic, intuitionistic logic, and quantum logic . These logics are related in an interesting way and are not far apart from each other, as is widely believed. The results in this paper show how they are related with each other through a dual intuitionistic logic . Our study is completely syntactical.

Research interest in cuteness perception and its effects on subsequent behavior and physiological responses has recently been increasing. The purpose of the present study was to produce a dataset of Japanese infant faces that are free of portrait rights and can be used for cuteness research. A total of 80 original facial images of 6-month-old infants were collected from their parents. The cuteness level of each picture was rated on a 7-point scale by 200 Japanese people. Prototypical high- and low-cuteness (...) faces were created by averaging the top 10 and bottom 10 faces according to the mean cuteness ratings. Then, 50 composite faces were made by mixing two faces randomly chosen from the 60 unused middle-cuteness faces. The normative cuteness ratings of these composite faces were obtained from 229 Japanese men and women in their 20s–60s. The shape of each composite face was transformed to be cuter or less cute along a continuum between the high- and low-cuteness prototypical faces. A two-alternative forced-choice task confirmed that cuteness discrimination was better than the chance level for all 50 face pairs. Moreover, the results showed that young men had poorer sensitivity to cuteness differences in infant faces than older men and women of any age. This Japanese Cute Infant Face dataset, including composite face images and normative rating scores, is publicly available online. (shrink)

Dominant interpretations of Plato's Crito attempt to reconstruct the text deductively, taking the arguments in the famous Laws’ speech as consisting solely in the application of general principles to facts. It is thus conceived that the principles and facts are grasped independently of each other, and then the former are applied to the latter, subsequently reaching the conclusion that Socrates must not escape. Following the lead of Cora Diamond, who argues against this ‘generalist interpretation’, I argue that the Laws’ speech (...) essentially involves an exercise of our moral imagination through which both principles and the facts to which they apply are grasped. This is not to say that a deductive argument is absent from the Laws’ speech. Rather, for the first time, we understand how the deductive arguments in the Laws’ speech can function through imagining a life in which these arguments make sense. The Crito is an attempt to exercise the readers’ imagination, thereby presenting ethics that is both personal and objective. Understanding the Laws’ arguments essentially requires the readers’ imaginative involvement with Socrates’ personal story, but they still have objective import. (shrink)

A proof is given for the theorem that at least one bound state exists in a one-dimensional attractive potential however weak it may be. The proof is constructive in that it provides a method to explicitly solve the eigenvalue problem for the eigenvalues as well as the eigenfunctions. The method is well suited to precise numerical calculations.

Immunity against SARS‐CoV‐2 that is acquired by convalescent COVID‐19 patients is examined in reference to (A) the Th17 cell generation system in psoriatic epidermis and (B) a recently discovered phenomenon in which Th17 cells are converted into tissue‐resident memory T (TRM) cells with Th1 phenotype. Neutrophils that are attracted to the site of infection secrete IL‐17A, which stimulates lung epithelial cells to express CCL20. Natural Th17 (nTh17) cells are recruited to the infection site by CCL20 and expand in the presence (...) of IL‐23. These nTh17 cells are converted to TRM cells upon encounter with SARS‐CoV‐2 and continue to exist as ex‐Th17 cells, which exert Th1‐like immunity during a memory response. G‐CSF can induce nTh17 cell accumulation at the infection site because it promotes neutrophil egress from the bone marrow. Hence, G‐CSF may be effective against COVID‐19. Administration of G‐CSF to patients infected with SARS‐CoV‐2 is worth a clinical trial. (shrink)