High degrees of uncertainty and a lack of effective therapeutic treatments have characterized the COVID-19 pandemic and the provision of drug products outside research settings has been controversial. International guidelines for providing patients with experimental interventions to treat infectious diseases outside of clinical trials exist but it is unclear if or how they should apply in settings where clinical trials and research are strongly regulated. We propose the Professional Oversight of Emergency-Use Interventions and Monitoring System as an alternative pathway based (...) on guidance developed for the ethical provision of experimental interventions to treat COVID-19 in Singapore. We support our proposal with justifications that establish moral duties for physicians to record outcomes data and for institutions to establish monitoring systems for reporting information on safety and effectiveness to the relevant authorities. Institutions also have a duty to support generation of evidence for what constitutes good clinical practice and so should ensure the unproven intervention is made the subject of research studies that can contribute to generalizable knowledge as soon as practical and that physicians remain committed to supporting learning health systems. We outline key differences between POEIMS and other pathways for the provision of experimental interventions in public health emergencies. (shrink)

Background We aimed to examine the ethical concerns Singaporeans have about sharing health-data for precision medicine and identify suggestions for governance strategies. Just as Asian genomes are under-represented in PM, the views of Asian populations about the risks and benefits of data sharing are under-represented in prior attitudinal research. Methods We conducted seven focus groups with 62 participants in Singapore from May to July 2019. They were conducted in three languages and analysed with qualitative content and thematic analysis. Results Four (...) key themes emerged: nuanced understandings of data security and data sensitivity; trade-offs between data protection and research benefits; trust in the public and private sectors; and governance and control options. Participants were aware of the inherent risks associated with data sharing for research. Participants expressed conditional support for data sharing, including genomic sequence data and information contained within electronic medical records. This support included sharing data with researchers from universities and healthcare institutions, both in Singapore and overseas. Support was conditional on the perceived social value of the research and appropriate de-identification and data security processes. Participants suggested that a data sharing oversight body would help strengthen public trust and comfort in data research for PM in Singapore. Conclusion Maintenance of public trust in data security systems and governance regimes can enhance participation in PM and data sharing for research. Contrary to themes in much prior research, participants demonstrated a sophisticated understanding of the inherent risks of data sharing, analysed trade-offs between risks and potential benefits of PM, and often adopted an international perspective. (shrink)

Owen Flanagan argues that we are on the way to understanding consciousness and its place in the natural order.

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Abstract:When people reason on the basis of moral rules, do they suppose that in the absence of a prohibitory rule they are free to act, or do they suppose that morality always requires a justification establishing a permission to act? In this essay we present a series of learning experiments that indicate when learners tend to close their system on the basis of natural liberty and when on the principle of residual prohibition. Those who are taught prohibitory rules tend to (...) infer natural liberty while those taught permission rules tend to infer residual prohibition. In mixed cases, where learners are taught both types of rules, there is some tendency to suppose that natural liberty is the default. Both natural liberty and its denial can be learned; is there a reason to adopt one system of moral rules or the other? We argue that systems of social morality based on a principle of natural liberty have a striking advantage over their competitors: they are well adapted to effectively exploring the constant novel circumstances that arise in open, dynamic, societies. (shrink)

In virtue of its form [‘I am here’] must be true on any occasion on which [it is] asserted, and yet the proposition it expresses on each occasion [is] contingent. Intuitively, [‘I am here now’] is deeply, and in some sense universally, true. One need only understand the meaning of [it] to know that it cannot be uttered falsely. The sentence ‘I am here’ has the peculiar property that whenever I utter it, it is bound to be true. Even if (...) I am lost and do not know where I am, I can bravely say ‘I am here’, and know that I am expressing a truth. (shrink)

In Dreaming Souls, Owen Flanagan provides both an accessible survey of the latest research on sleep and dreams and a compelling new theory about the nature and function of dreaming. Flanagan argues that while sleep has a clear biological function and adaptive value, dreams are merely side effects, 'free-riders', irrelevant from an evolutionary point of view. But dreams are hardly unimportant. Indeed, Flanagan argues that dreams are self-expressive, the result of our need to find or create meaning, even when (...) we are sleeping. (shrink)

I INTRODUCTION - THE TOPIC EXPLAINED 1 GENERAL DIFFERENCES From its inception to the present, philosophy may be viewed as a series of struggles between ...

Ethics consultation is a novel paradigm in European health-care institutions. In this paper, patient involvement in all clinical ethics activities is scrutinized. It is argued that patients should have access to case consultation services via clearly defined access paths. However, the right of both health-care professionals and patients indicates that patients should not always be notified of a consultation. Ethics education, another well-established function of an ethics committee, should equally be available for patients, lay people and hospital staff. Beyond access (...) and utilization, lay membership on a clinical ethics service is a matter of transparency, equal participation, empowerment and democratization. Lay and patient perspectives will contribute to the quality of ethics services on all levels from case consultations to ethics education and policy development. (shrink)

The evidence of blindsight is occasionally used to argue that we can see things, and thus have perceptual belief, without the distinctive visual awareness accompanying normal sight; thereby displacing phenomenality as a component of the concept of vision. I maintain that arguments to this end typically rely on misconceptions about blindsight and almost always ignore associated visual (or visuomotor) pathologies relevant to the lessons of such cases. More specifically, I conclude, first, that the phenomena very likely do not result from (...) dissociations within a single system, but from the interaction of evolutionarily distinct, if interacting, systems; second, that a closer study of spared motor abilities indicates that verbal responses of patients result not from degraded vision but from proprioception; and, finally, above chance verbal responses, being forced guesses, are not tentative beliefs and cannot become beliefs just by training patients to have more confidence in their responses. (shrink)

G. E. L. Owen; VIII*—Aristotelian Pleasures, Proceedings of the Aristotelian Society, Volume 72, Issue 1, 1 June 1972, Pages 135–152, https://doi.org/10.1093/ar.

Catholic moral theology possesses a number of tools that can be employed to promote worker justice. Some of these tools, such as Catholic social teaching on solidarity and workers’ rights, have been used to this end before. However, advocates of workers’ rights have seldom utilized other concepts, such as cooperation in evil, scandal, and evangelization. This essay provides a theoretical introduction to several tools in the “toolkit” of Catholic ethicists, engaging contemporary scholarship on them. It then applies the concepts to (...) two cases in order to demonstrate their usefulness in the struggle for worker justice. Both cases involve Catholic universities, which means the ethical concepts introduced from the Catholic moral tradition should have normative status for these institutions. The first case entails a divestment campaign at the University of Notre Dame. The second case confronts the unjust treatment of adjunct faculty members at Catholic colleges and universities. (shrink)

Many of the debates concerning the existence of economic rights obfuscate the meaning of the possession of a right to an economic good. In order to provide clarification, several theoretical questions must be probed. This essay explores each of these issues in order to demonstrate that greater conceptual clarity repudiates the arguments against the existence of economic rights. It also seeks to attenuate the vexing problem of necessary and painful tradeoffs between competing rights claims. The final portion of this essay (...) heuristically demonstrates how greater conceptual clarity can aid us in dealing with complex policy issues involving competing rights claims. (shrink)

Recently, a number of Anglo-American philosophers of very different sorts--pragmatists, metaphysicians, philosophers of language, philosophers of law, moral philosophers--have taken a reflective rather than merely recreational interest in literature. Does this literary turn mean that philosophy is coming to an end or merely down to earth? In this collection of essays, one of the most insightful of contemporary literary theorists investigates the intersection of literature and philosophy, analyzing the emerging preferences for practice over theory, particulars over universals, events over structures, (...) inhabitants over spectators, an ethics of responsibility over a morality of rules, and a desire for intimacy with the world instead of simply a disengaged knowledge of it. (shrink)

In this essay I sketch a philosophical argument for classical liberalism based on the requirements of public reason. I argue that we can develop a philosophical liberalism that, unlike so much recent philosophy, takes existing social facts and mores seriously while, at the same time, retaining the critical edge characteristic of the liberal tradition. I argue that once we develop such an account, we are led toward a vindication of “old” (qua classical) liberal morality—what Benjamin Constant called the “liberties of (...) the moderns.” A core thesis of the paper is that a regime of individual rights is crucial to the project of public justification because it disperses moral authority to individuals thus mitigating what I call the “burdens of justification.” Footnotesa Earlier versions of this essay were presented at the University of North Carolina, Chapel Hill, Philosophy Department workshop on the morality of capitalism, and at the conference on rights theory at the Murphy Institute, Tulane University. I am grateful for the comments of the participants; my special thanks to David Schmidtz, Julian Lamont, and Andrea Houchard for their useful written comments and suggestions. (shrink)

First published in 2012, Doing Philosophy presents the basics of how 'to do' philosophy -- what philosophy is, how we can think, the nature of logic, some special terms -- in a straightforward and easy to understand style. Then, using questions and exercises as well as everyday examples, the author takes the reader on a wide-ranging tour of key philosophical topics which, as well as the 'standard fare' of logic, epistemology, mind, God etc., also includes ethical, social, scientific, cultural and (...) human issues such as time, cosmology, war, animal rights, euthanasia, abortion, genetics, evolution, and the meaning of life. The author's emphasis throughout is that philosophy is accessible to anyone keen enough to try and do it and that, as a subject, philosophy is practical, fascinating and exciting. By encouraging independent critical thinking and being succinct yet informative, the book involves the reader with the history, the breadth of subject matter, the skills of philosophising and the benefits that philosophy can offer to the enquiring individual. The book accesses major philosophical topics briefly, breaking them down into convenient points, with challenging questions throughout and exercise questions at the end of each chapter, whilst introducing major thinkers and their ideas. There is an extensive further reading list to help those who wish to take this absorbing subject further. (shrink)

Siegel argues that the Kuhnian relativism presented in ?Kuhn's Epistemological Relativism? fails because it neglects the possibility of rational choice in science between rival paradigms? own incommensurable standards on the basis of ?paradigm?neutral external standards?. In reply, it is argued (1) that Siegel has given no reason to believe that there are such external standards in science, (2) that the mere ?possibility? of such standards in scientific debate is not sufficient to vitiate Kuhn's relativism, (3) that the actual existence of (...) rational debate concerning the internal standards of rival paradigms does not entail (as Siegel claims) the existence of ?paradigm?neutral external standards?, and finally (4) that Kuhn's relativism concerning standards in science does not lead (as Siegel claims) to a ?reductio? which undermines the philosophical standards implicit in Kuhn's argument. (shrink)

Prologue : on the freedom of non-identity -- Otherwise than human (toward sovereignty) -- What is human recognition? (on zones of indistinction) -- Desubjectivation (Michel Foucault's aesthetics of experience) -- Becoming animal (some simple ways) -- Derrida's cat (who am I?).

Parmenides didn't mention reference as such, but if he had he would have undoubtedly agreed with the philosophers who nowadays hold what is called "the axiom of existence": that one can only refer to what exists. The sources of possible support for this view are examined and rejected. Primary support for the axiom is given by two sorts of argument; one concerning quantification, the other summarizing a standard Parmenidean puzzle. Weaknesses in both are exposed. Finally, the relations between the axiom (...) and connected claims about predication and truth are probed, and an attempt is made to determine the limits of the mutual support these claims give one another. (shrink)

Under the title of ‘the axiom of existence’, hereafter, John R. Searle has reduced to compact dictum a view to which many philosophers subscribe: ‘Whatever is referred to must exist’. In this paper I shall offer two major arguments against adopting, at least on certain assumptions. There have been a number of defenses of, among them those arguing that it is fundamental to any systematic philosophy of language or logic. With the exception of discussing some of Searle's remarks in part (...) Ill of this paper I shall not comment on any of these defenses. (shrink)

For Bernard Williams, philosophy and history are importantly connected. His work exploits this connection in a number of directions: he believes that philosophy cannot ignore its own history the way science can; that even when engaging with philosophy’s history primarily to produce history, one needs to draw on philosophy; and that when doing the history of philosophy primarily to produce philosophy, one still needs a sense of how historically distant past philosophers are, because the point of reading them is to (...) confront something different from the present. But Williams also holds that systematic philosophy itself needs to be done historically, engaging not just with its own history, but with that of the concepts it seeks to understand. To explore these different ways in which philosophy and history intertwine, this volume assembles specially commissioned contributions by A. W. Moore, Terence Irwin, Sophie-Grace Chappell, Catherine Rowett, Marcel van Ackeren, John Cottingham, Gerald Lang, Lorenzo Greco, Paul Russell, Carla Bagnoli, Peter Kail, David Owen, Giuseppina D’Oro, James Connelly, Matthieu Queloz, Nikhil Krishnan, John Marenbon, Ralph Wedgwood, Garrett Cullity, Hans-Johann Glock, Geraldine Ng, Ilaria Cozzaglio, Amanda R. Greene, and Miranda Fricker. They critically appraise Williams’s work in and on the history of philosophy as well as his historicist turn and his use of genealogy. The resulting collection uniquely combines substantive discussions of historical figures from Homer to Wittgenstein with methodological discussions of how and why the history of philosophy should be done, and how and why philosophy should draw on history. (shrink)

L’ouvrage que publie Valérie Beaudouin, tiré de sa thèse soutenue en 2000, se signale par de nombreuses qualités, parmi lesquelles on distinguera l’ampleur de la matière étudiée, l’originalité de la démarche et des méthodes, l’intérêt neuf et majeur de maints résultats, le renouvellement méthodologique qu’il apporte dans le domaine de la métrique française. L’auteur s’est proposé de décrire le vers du théâtre classique, en s’appuyant sur un corpus constitué de la totalité des pièces de Cornei...

[Herbert F.] Tucker has shown us in a very practical way that the concept of meaning is the problem of problems, not only in hermeneutics but in literary theory and, indeed, literary study generally. It may well be that in literary study there can be no talk of meaning that is not ambiguous, that does not require us to speak in figures or by means of metaphorical improvisations. It would not necessarily follow that our talk of meaning is merely provisional (...) or without philosophical authority since we know now that considerable authority attaches to ordinary language, whence we obtain our use of the word "meaning" as well as the figurations that we use to talk our way around it. To be sure, the discipline of literary study is now rapidly filling with grave masters who take our figures to mean that meaning is literally unspeakable—only so many transferences and substitutions within a system of differences alarmingly vast . This is itself a terrific idea, or a terrific figure, although it is used mainly to expose the thoughtless way we talk about meaning as well as our offhand assumptions about the conditions that make understanding possible. Our problem in literary study is not that meaning is unspeakable—even if it were it would not be a problem—but that we rarely reflect on the subject of meaning in a disciplined way. In our time, meaning as a topic of study is the preserve of logicians. It is almost exclusively a theme of analytical philosophy, and even those not bound by this philosophy address themselves to the analytical tradition when they speak of meaning.1 It is time that we entered into this discourse on meaning; a paper as fine as Tucker's should serve as a summons.· 1. Among numerous cases, see John R. Searle, "Metaphor" and "Literal Meaning," Expression and Meaning , pp. 76-136, and "Intentionality and the Use of Language," in Meaning and Use, ed. Avishai Margalit , pp. 181-97.Gerald l. Bruns, professor of English at the University of Iowa, is the author of Modern Poetry and the Idea of Language and Inventions: Writing, Textuality, and Interpretation in Literary History. (shrink)

I am impressed by how angry Jonathan Crewe is, but I found his remarks confused and unclear and so I’m uncertain how to reply. Whatever the matter it, he wants “to forestall a sense of academic obligation on anyone’s part to work back to Cavell through Bruns” . God knows this might be a good idea, judging from what James Conant says.Conant’s criticisms are directed at the section of my paper called “The Moral of Skepticism,” which he cannot help wanting (...) to rewrite, since he has a much more intimate grasp of Cavell’s thinking than I have. I imagined myself on the outside of Cavell’s texts, trying to characterize them in a certain way, not on the inside, giving an account of their genesis. Obviously my paper is neither philosophy nor literary criticism but a crossdressing of the two that is bound to make someone like Crewe bite his teeth. I appreciate Conant’s forbearance. Gerald L. Bruns is William and Hazel White Professor of English and Comparative Literature at the University of Notre Dame. His most recent book is Heidegger’s Estrangements: Language, Truth, and Poetry in the Later Writings. (shrink)