Studies of the regulation of heme oxygenase by synthetic metalloporphyrins reveal that within this group of compounds there exist both inducers and inhibitors of the synthesis of this enzyme or of its catalytic function. The ability of metalloporphyrins to alter heme catabolism is of considerable experimental and clinical interest since such alterations may have consequences for other aspects of heme homeostasis, including its synthesis and its function in the form of cytochrome(s) P‐450. Examples of the metabolic effects – and their (...) potential clinical and pharmacological consequences – produced by two synthetic metalloporphyrins, Sn‐protoporphyrin and Co‐protoporphyrin, are discussed. (shrink)

CONTENTS: Walter Hopp: How to Think about Nonconceptual Content Jeff Yoshimi: Husserl on Psycho-Physical Laws Mark van Atten: Construction and Constitution in Mathematics Ronald Bruzina: Husserl's "Naturalism" and Genetic Phenomenology Andrea Staiti: Different Worlds and Tendency to Concordance: On Husserl's Phenomenology of Culture Rosemary R. P. Lerner : The Cartesian Meditations' Foundational Discourse: An Obsolete Project? Sebastian Luft: Lerner on Foundation, Person, and Rationality George Heffernan: The Phronimos, the Phainomena, and the Pragmata: Are We Responsible for the Things that (...) Appear to Us to Be Good for Us? Michael J. Sigrist: Husserl on God, Existence, and Transcendental Analysis Hans Pedersen: On Heidegger's Appropriation of Aristotle's Concept of Phronesis Ka-wing Leung: Heidegger on Animal and World Abraham Stone: On the Teaching of Virtue in Plato's Meno and the Nature of Philosophical Authority Michael Kelly: A Glimpse of Envy and its Intentional Structure Anne C. Ozar : The Value of a Phenomenology of the Emotions for Cultivating One's Own Character Review Essay Molly Brigid Flynn: The Agent of Truth: Reflections on Robert Sokolowski's Phenomenology of the Human Person (Noesis 2011). (shrink)

CONTENTS An Editor's Introduction INTRODUCTORY CHRONOLOGICAL OVERVIEW HEIDEGGER'S ACADEMIC CAREER 1909-1930 A. Background B. Lehrveranstaltungen/University Education and Teaching C. Heidegger's Early Occasional Writings: A Chronological Bibliography PART I: STUDENT YEARS 1. Curricula Vitae 2. Two Essays for The Academician o Authority and Freedom o On a Philosophical Orientation for Academics 3. The Problem of Reality in Modern Philosophy 4. Recent Research in Logic 5. Meßkirch's Triduum: A Three-day Meditation on the War 6. Question and Judgment 7. The Concept of Time (...) in the Science of History 8. The Doctrine of Categories and Meaning in Duns Scotus : Supplements o Author's Notice o Conclusion: The Problem of Categories 9. On Schleiermacher's Second Speech "On the Essence of Religion" PART II: EARLY FREIBURG PERIOD 10. Letter to Engelbert Krebs on his Philosophical Conversion 11. Letter to Karl L÷with on his Philosophical Identity 12. Vita, with an Accompanying Letter to Georg Misch 13. Critical Comments on Karl Jaspers' Psychology of Worldviews 14. Phenomenological Interpretations with Respect to Aristotle: Indication of the Hermeneutical Situation PART III: THE MARBURG PERIOD 15. The Problem of Sin in Luther 16. The Concept of Time 17. Being-There and Being-True According to Aristotle 18. Wilhelm Dilthey's Research and the Current Struggle for a Historical Worldview 19. On the Essence of Truth, Pentecost Monday 20. Letter Exchange with Karl L÷with on Being and Time 21. "Phenomenology," Draft B, with Heidegger's Letter to Husserl 22. "Heidegger, Martin": Lexicon Article Attributed to Rudolf Bultmann APPENDICES: SUPPLEMENTS BY HEIDEGGER'S CONTEMPORARIES Appendix I: Academic Evaluations of Heidegger by his Teachers and Peers A. Evaluation of Martin Heidegger's Dissertation by Arthur Schneider B. Evaluation of Dr. Heidegger's Habilitation by Heinrich Rickert C. Nomination for Associate Professor at G÷ttingen D. Nomination for Associate Professor at Marburg E. Nomination for Professor at Marburg F. Nomination for Husserl's Chair at Freiburg Appendix II: Husserl and Heidegger A. Their Correspondence to and about Each Other B. "For Edmund Husserl on his Seventieth Birthday" Appendix III: Karl L÷with's Impressions of Husserl and Heidegger, 1926-1927 Annotated Glossary Bibliography of GA-Editions of the Lecture Courses Select Secondary Bibliography. (shrink)

CONTENTS An Editor's Introduction INTRODUCTORY CHRONOLOGICAL OVERVIEW HEIDEGGER'S ACADEMIC CAREER 1909-1930 A. Background (1889-1930) B. Lehrveranstaltungen/University Education and Teaching (1909-1930) C. Heidegger's Early Occasional Writings: A Chronological Bibliography PART I: STUDENT YEARS 1. Curricula Vitae 2. Two Essays for The Academician o Authority and Freedom (1910) o On a Philosophical Orientation for Academics (1911) 3. The Problem of Reality in Modern Philosophy (1912) 4. Recent Research in Logic (October-December 1912) 5. Meßkirch's Triduum: A Three-day Meditation on the War (January 1915) (...) 6. Question and Judgment (July 1915) 7. The Concept of Time in the Science of History (July 1915) 8. The Doctrine of Categories and Meaning in Duns Scotus (1915): Supplements o Author's Notice (1917) o Conclusion: The Problem of Categories (1916) 9. On Schleiermacher's Second Speech "On the Essence of Religion" (1917) PART II: EARLY FREIBURG PERIOD 10. Letter to Engelbert Krebs on his Philosophical Conversion (1919) 11. Letter to Karl L÷with on his Philosophical Identity (1921) 12. Vita, with an Accompanying Letter to Georg Misch (June 1922) 13. Critical Comments on Karl Jaspers' Psychology of Worldviews (1920) 14. Phenomenological Interpretations with Respect to Aristotle: Indication of the Hermeneutical Situation (1922) PART III: THE MARBURG PERIOD 15. The Problem of Sin in Luther (February 1924) 16. The Concept of Time (July 1924) 17. Being-There and Being-True According to Aristotle (December 1924) 18. Wilhelm Dilthey's Research and the Current Struggle for a Historical Worldview (Kassel Lectures, April 1925) 19. On the Essence of Truth, Pentecost Monday (May 24, 1926) 20. Letter Exchange with Karl L÷with on Being and Time (August 1927) 21. "Phenomenology," Draft B (of the Encyclopaedia Britannica Article), with Heidegger's Letter to Husserl (October 1927) 22. "Heidegger, Martin": Lexicon Article Attributed to Rudolf Bultmann (1927-1928) APPENDICES: SUPPLEMENTS BY HEIDEGGER'S CONTEMPORARIES Appendix I: Academic Evaluations of Heidegger by his Teachers and Peers A. Evaluation of Martin Heidegger's Dissertation by Arthur Schneider (July 1913) B. Evaluation of Dr. Heidegger's Habilitation by Heinrich Rickert (July 1915) C. Nomination for Associate Professor at G÷ttingen (November 1922) D. Nomination for Associate Professor at Marburg (December 1922) E. Nomination for Professor at Marburg (August 1925) F. Nomination for Husserl's Chair at Freiburg (February 1928) Appendix II: Husserl and Heidegger A. Their Correspondence to and about Each Other (1914-1934) B. "For Edmund Husserl on his Seventieth Birthday" (April 8, 1929) Appendix III: Karl L÷with's Impressions of Husserl and Heidegger, 1926-1927 Annotated Glossary Bibliography of GA-Editions of the Lecture Courses Select Secondary Bibliography. (shrink)

One day, Matthew Eaton was walking through an impromptu animal shelter display at his local pet store when suddenly an eight-month-old kitten dug his claws into Eaton’s flesh. Eaton recognized that the “eyes of this cat and the curve of his claw” compelled a response analogous to those found in the writings of Buber, Levinas, and Derrida. And not just Eaton but a whole community of theologians have found themselves in an encounter with particular places and animals that demands rich (...) theological reflection. Eaton enlisted fellow editors Harvie and Bechtel to collect the essays in this volume, in which theologians listen to horses, rats, snakes, cats, dogs, and the earth itself, who become new theological voices demanding a response. In this volume, the voice of the more-than-human world is heard as making theology possible. These essays suggest that what we say theologically represents not simply ideas of our own making subsequently superimposed onto the natural world through our own discovery, but rather flow from an expressive Earth. With additional contributions from: Kimberly Carfore Lisa E. Dahill Celia Deane-Drummond Heather Eaton Nathan Kowalsky Abigail Lofte Jame Schaefer Cristina D. Vanin Mark Wallace Grace Y. Kao Chris Carter John Berkman Laura Hobgood. (shrink)

George S. Counts was a_ _major figure in American education for almost fifty years. Republication of this early work draws special attention to Counts’s role as a social and political activist. Three particular themes make the book noteworthy because of their importance in Counts’s plan for change as well as for their continuing contem­porary importance: _ _Counts’s crit­icism of child-centered progressives; _ _the role Counts assigns to teachers in achieving educational and social re­form; and Counts’s idea for the re­form (...) of the American economy. (shrink)

The opening lines of Franz Delitzsch's Babel und Bibel offer an unusually frank confession of the personal and psychological motives that animated German orientalism in the nineteenth and early twentieth centuries. For Delitzsch and countless others like him, orientalist scholarship provided an opportunity not just to expand their knowledge of the Near East and India, but also to explore the world of the Bible and, in doing so, effect a reckoning with the religious beliefs of their childhoods. In German Orientalism (...) in the Age of Empire, Suzanne Marchand opens up this scholarly world, exploring the criss-crossing forces and interests that shaped it, while effecting her own reckoning with orientalism as a historical and historiographical phenomenon. (shrink)

An attractor network was trained to compute from word form to semantic representations that were based on subject‐generated features. The model was driven largely by higher‐order semantic structure. The network simulated two recent experiments that employed items included in its training set (McRae and Boisvert, 1998). In Simulation 1, short stimulus onset asynchrony priming was demonstrated for semantically similar items. Simulation 2 reproduced subtle effects obtained by varying degree of similarity. Two predictions from the model were then tested on human (...) subjects. In Simulation 3 and Experiment 1, the items from Simulation 1 were reversed, and both the network and subjects showed minimally different priming effects in the two directions. In Experiment 2, consistent with attractor networks but contrary to a key aspect of hierarchical spreading activation accounts priming was determined by featural similarity rather than shared superordinate category. It is concluded that semantic‐similarity priming is due to featural overlap that is a natural consequence of distributed representations of word meaning. (shrink)

The natural sciences are sometimes called "hard" sciences in contrast to the social sciences , which are thought to represent "soft" sciences. L. V. Hedges made an important effort to determine the empirical cumulativeness of various scientific research programs, with an eye toward assessing if this criterion is related to a discipline's "hardness" or "softness." This article discusses another criterion, a research program's predictive accuracy, that might also be considered along with a program's empirical cumulativeness. Finally, recent improvements in the (...) predictive accuracy of multifaceted psychological theories are discussed. 2012 APA, all rights reserved). (shrink)

Three recently published books, by Stavros Tombazos, Jonathan Martineau, and Harry Harootunian, join a now established body of literature that highlights the temporal aspects of Marx’s work. Their differences notwithstanding, these books are united by the conviction that, at its core, capitalism is an immense and complex organisation of time, and thus that the importance of Marx’s work is realised by its singular contribution to our understanding of this. Each book is centrally concerned with the historically specific character of capital’s (...) temporal order, such that each presents a new reading of the relationship between capitalism and historical time. (shrink)

This fourth edition of one of the classic logic textbooks has been thoroughly revised by John Burgess. The aim is to increase the pedagogical value of the book for the core market of students of philosophy and for students of mathematics and computer science as well. This book has become a classic because of its accessibility to students without a mathematical background, and because it covers not simply the staple topics of an intermediate logic course such as Godel's Incompleteness Theorems, (...) but also a large number of optional topics from Turing's theory of computability to Ramsey's theorem. John Burgess has now enhanced the book by adding a selection of problems at the end of each chapter, and by reorganising and rewriting chapters to make them more independent of each other and thus to increase the range of options available to instructors as to what to cover and what to defer. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:Perception of the Self George S. Pappas Differences of detail aside, we may think ofboth Locke and Berkeley as accepting the same view of the mind. They agree that there are minds, and that each mind is a simple, immaterial substance. Sometimes the word 'soul' is used instead of'mind'; but in this context, the different terminology is not consequential. Moreover, Locke and Berkeley employ essentially the same argument (...) for their shared view about minds. More exactly, they use the same argument for the limited thesis that there is something distinct from perceptions and from ideas perceived, and that this somethingis aperceiver, or that which perceives. The argument, given in more detail below, claims that we are aware ofour own minds in, or while we are engaged in, perception. The kind ofawareness is said to be or to involve a reflex act, a concept we associate with Berkeley, though I think it is one he appropriated from Locke. Hume, ofcourse, rejects the view ofLocke and Berkeley. He rejects the very notion of an immaterial mind or soul, finding it to be meaningless. And he rejects as well the limited thesis that there is something which perceives and which is distinct from all perceptions. In this paper I will restrict attention to Hume's arguments for rejecting the limited thesis. 1. Rejection ofthe limited thesis Hume investigates the limited thesis of Locke and Berkeley in the well-known section ofthe Treatise which deals with personal identity (Treatise 1.4.6). Here is how he expresses the view of "some philosophers": Theke are some philosophers, who imagine we are every moment intimately conscious of what we call our SELF; that we feel its existence and continuance in existence; and are certain, beyond the evidence of a demonstration, both of its perfect identity and simplicity. The strongest sensation, the most violent passion, say they, instead of distracting us from this view, only fix it the more intensely, and make us consider their influence on selfeither by their pain or pleasure.1 Thus, Hume represents the argumentofthosehe opposes as containing two premises: Volume XVIII Number 2 275 GEORGE S. PAPPAS (1)In perception, one is aware ofone's self, and aware ofthe simplicity of the self. (2)In being thus aware of the self and its simplicity one gains an idea of a simple self. These premises, in turn, support a double conclusion: (3)There are simple selves (minds). (4)We have an idea of a simple self(mind). Hume does not take the trouble to cite the second premise given here in the passage I have quoted, butitis clear that he has it in mind, since he proceeds directly to a criticism of it. The criticism is quite familiar inform, encapsulatingwhat I call aderivabilityargument. Here is what Hume says: all these positive assertions are contrary to that very experience, which is pleaded for them, nor have we any idea of self, after the manner it is here explain'd. For from what impression cou'd this idea be deriv'd?... It must be some one impression, that givesrise toeveryreal idea. But selfor person is not any one impression, but that to which our severahmpressionsandideas are suppos'd to have areference. Ifany impression gives rise to the idea ofself, that impression must continue invariably the same, thro' the whole course of our lives; since self is suppos'd to exist after that manner. (T 251) He is also sharply critical ofthe first premise. Hume says: when I enter most intimately into what I call myself, I always stumble on some particularperception orother, ofheatorcold, light or shade, love or hatred, pain or pleasure. I never can catch myselfat any time without a perception, and never can observe any thing but the perception. (T 252) So, minimally, Hume's arguments amount to this: (1) is false; hence, we have nogroundforclaiming(3). Similarly, (2) is false, so that we have no ground for claiming (4). Actually, of course, Hume asserts stronger claims, maintaining that (3) and (4) arefalse, and not merely that we lack adequate support forthem. Buttoshowtheirfalsityrequires additional argumentbeyond whatis providedin the above-quoted passages. Here I will not consider those additional arguments, except to note... (shrink)

In lieu of an abstract, here is a brief excerpt of the content:167. ON McRAE' S HUME Professor McRae's interesting paper may be rather naturally divided into two parts. In the first part he explains what he takes Hume's account of time to be; in the second he advances the bold thesis that Hume's account of time, or perhaps of duration, provides a basis or foundation for his more widely discussed remarks on identity, substance, the self, the necessary connections. In (...) what follows I first reconstruct Professor McRae' s paper, and then I raise some problems, perhaps puzzles, about Hume's view on duration, time and fictions. According to McRae, some philosophers (Descartes, Spinoza, Leibniz) distinguish between time and duration, both of which are taken to be perfectly legitimate notions. Hume, by contrast, takes time and duration to be the same, viz., a succession of moments. What philosophers and the vulgar call 'duration' is something quite different, namely a single unbroken stretch of time which is not composed of successive parts. Of duration taken in this latter way, McRae says, Hume has four things to say, all of them negative: (1) we have no idea of duration; (2) no object has duration; (3) there is no such thing as duration; and (4) duration is a fiction. Properly understood as a succession of moments, however, time certainly exists and is thus not a fiction. Moreover, we have the or at least an idea of time, despite the fact that it is obtained without derivation from a precedent impression. And, while no object can be said to have time, Hume will nonetheless allow that objects exist at certain times and perhaps across a time span. In the second part of his paper, Professor McRae distinguishes two types of Humean fictions. The first arises when one idea is confused with another and mis-applied to some object. The second arises when the imagination creates an "idea" in the attempt to resolve a 168. contradiction which comes up when the first fiction is applied to an object. What I have called McRae' s "bold thesis" in the second part of his paper can now be stated. Duration, or the putative idea thereof, is a fiction of the first type, one that is attributed to what Hume calls "steadfast objects." However, such an object can be considered in two ways. One might consider the object at two stages of this duration and, McRae says, "...this will give us the idea of number" (p. 126); or, one might consider in turn a series of objects, each of them supposedly "steadfast," all along supposing that though time is changing, the objects are not, and "...in this way- we get the idea of unity" (Ibid.). But no object is both a unity and a multiplicity. So, to reconcile these conflicting considerations, the "idea" or fiction of identity is invented. As McRae says: "The idea of identity is a pure product of the imagination invented to mediate between unity and number" (Ibid. ). This invented "idea" is then mis-applied (a fiction of type one) to interrupted appearances of an object. To reconcile the supposed identity of an object with successive appearances of it, the fiction of substance is invented. Quoting both McRae and Hume, In order to reconcile the contradiction between identity and diversity, the imagination is apt to feign something unknown and invisible, which it supposes to continue the same under all these variations ; 2 and this unintelligible something it calls a substance... (p. 128). Related needs to resolve contradictions, on McRae' s account, lead to the fictions of the self (p. 128) and of necessary connections (p. 130), though the latter fiction is of type one. Hence, McRae' s "bold thesis" amounts to this: Duration is a fiction. In the attempt to apply this fiction, one is led to, logically led to, most, if not all, of the other famous Humean fictions. And, if we allow that there are mental acts, for Hume, as well as impressions and ideas, "...then a fictitious duration will be attributed to 169. objects and by a progressive compounding of fictitious mental actions will give the world the ontological structure which it has for the vulgar belief we all share. It... (shrink)

The Most Important Book on Money You'll Ever Read Also Includes Acres of Diamond The Richest Man in Babylon is a transformative book that has changed the way millions of people think about money since it was first published in 1926. Through light, entertaining parables author George S. Clason shares profound truths about wealth and success that will revolutionize the way you relate to money and interact with your finances. Clason's wisdom has inspired countless readers to gain, grow, and (...) maintain their wealth, making this one of the most beloved finance books of all time. This special edition also includes the bonus book Acres of Diamond by Russell Conwell, a powerful exploration of the nature of true wealth. The Richest Man In Babylon is part of the GPS (Good, Practical, Simple) Guides to Life Series, which brings classic success books to a modern audience. Each edition features new modern design while staying true to the text of the original editions. (shrink)

Most current theories of category-specific semantic deficits appeal to the role of sensory and functional knowledge types in explaining patients' impairments. We discuss why this binary classification is inadequate, point to a more detailed knowledge type taxonomy, and suggest how it may provide insight into the relationships between category-specific semantic deficits and impairments of specific aspects of knowledge.

Quantitative utilitarianism demands equal treatment of human and nonhuman animals where there are no relevant differences between them. A difference is relevant only if it excludes the animal from suffering evil if it is treated differently. Quantitative utilitarianism cannot, however, resolve conflicts of interest nor prove that painless killing of animals is morally wrong. For this we need a higher qualitativegood. I suggest Care, as Heidegger understands it, is such a good, and that it is the essence not only of (...) human, but of nonhuman animaI Dasein as well. Because animals care, we are morally obliged to desist from killing them, even painlessly. (shrink)