Should the philosophy of biology deal with organismic, or with molecular aspects , or with both ? We are, of course, not the first to appreciate the ...

In this research work a novel two-step system for anomaly detection is presented and tested over several real datasets. In the first step the novel Exploratory Projection Pursuit, Beta Hebbian Learning algorithm, is applied over each dataset, either to reduce the dimensionality of the original dataset or to face nonlinear datasets by generating a new subspace of the original dataset with lower, or even higher, dimensionality selecting the right activation function. Finally, in the second step Principal Component Analysis anomaly detection (...) is applied to the new subspace to detect the anomalies and improve its classification capabilities. This new approach has been tested over several different real datasets, in terms of number of variables, number of samples and number of anomalies. In almost all cases, the novel approach obtained better results in terms of area under the curve with similar standard deviation values. In case of computational cost, this improvement is only remarkable when complexity of the dataset in terms of number of variables is high. (shrink)

. Introductory Remarks THEODOSIUS DOBZHANSKY The problems of reduction in biology are currently of considerable theoretical interest and practical ...

In this paper I draw on Einstein's distinction between “principle” and “constructive” theories to isolate two levels of physical theory that can be found in both classical and (special) relativistic physics. I then argue that when we focus on theoretical explanations in physics, i.e. explanations of physical laws, the two leading views on explanation, Salmon's “bottom-up” view and Kitcher's “top-down” view, accurately describe theoretical explanations for a given level of theory. I arrive at this conclusion through an analysis of explanations (...) of mass—energy equivalence in special relativity. (shrink)

This work represents an attempt to stake out the landscape for dynamicism based on a radical dismissal of the information-processing paradigm that dominates the philosophy of cognitive science. In Section 2, after setting up the basic toolkit of a theory of minimal representationalism, I introduce the central tenets of dynamic systems theory (DST) by discussing recent research in the dynamics of embodiment (Thelen et al. [2001]) in the perseverative-reaching literature. A recent proposal on the dynamics of representation--the dynamic field approach (...) (Spencer and Schöner [2003])-- according to which the alleged representational gap between DST and representational theories of cognition needs to be bridged in order to explain higher-order cognitive activity will then be reviewed. In Section 3 I shall argue that Spencer and Schöner's attempt to bridge the representational gap may jeopardize the whole (antirepresentationalist) spirit of the DST project. In order to show why, I shall introduce the key concepts of "reliability of environment" and "primagenesis", and argue that DST can account for de-coupled, offline cognitive activity with no need of positing representational resources. Conclusions and directions for future research will follow. (shrink)

Aristóteles y G.E. Moore, los dos fundadores de la filosofía moral en épocas diferentes, son una especie de símbolo del combate que esta disciplina ha debido librar entre la Escila de un intelectualismo extremo y la Caribdis de un antiintelectualismo igualmente extremo. Los dos han luchado en pro de cierto cognitivismo en materia ética ¿Han escapado por ello a las tentaciones y a los reclamos del no-cognitivismo? ¿Y cuál de los dos se halla más cerca de la vida moral, tal (...) como ella transcurre realmente? ¿Cuál es el lugar efectivo de la razón en ésta y en la ética que la piensa? El autor investiga estas cuestiones en su obra, dedicadas, respectivamente, al dominio, las metas y los métodos de la filosofía moral. (shrink)

The Colombian conflict seems a typical instantiation of a “greedy war”and exhibits very strong links between criminal economic activities and rebel organizations. On the contrary, the author suggests that not even in Colombia does the “criminal rebels” thesis hold. On the other hand, the Colombian case shows that criminality and war mix in ways that escape a strictly economic interpretation of war.

This article examines multinational banks’ approaches to corporate social responsibility in developing countries’ subsidiaries, particularly in Latin America. Building on in-depth case studies of two MNBs that are based in Europe and market leaders in Latin America, we analyze their CSR motivations and outcomes in host countries. We examine institutional environments by applying the national business system framework, and we suggest missing categories in its financial and educational dimensions. We theorize how institutional necessity determines MNBs' CSR in developing countries. Finally, (...) we examine the CSR outcomes in Latin America, where banks’ responsible conduct has led to major improvements in educational levels and financial inclusion. These improvements alleviate poverty and enhance both country's social wellbeing and MNBs’ legitimacy, leading to mutual prosperity. (shrink)

Resumo: Pretendemos pensar as relações entre arte e sociedade, tendo sempre em mente a tensão irredutível entre a autonomia e a heteronomia de uma em relação a outra. Para tanto, traçaremos uma análise dos argumentos principais a respeito dessa relação dialética, em dois momentos distintos da reflexão filosófica sobre o tema. Em um primeiro momento, traremos a defesa de uma certa autonomia da arte com referência não apenas à sociedade que a produz, como também aos valores morais que são ensinados (...) através dela, com as reflexões e, sobretudo, com as críticas de Nietzsche sobre suas interpretações da tragédia clássica, a partir principalmente de O Nascimento da Tragédia, para, em um segundo momento, poder traçar um paralelo dessa argumentação com a constatação de Adorno a respeito da instrumentalização e da comercialização da arte, no contexto contemporâneo, expondo algumas das críticas de Nietzsche realizadas no séc. XIX sobre as produções culturais gregas do séc. IV a. C. e contextualizando-as em relação aos fenômenos estéticos contemporâneos.: We examine the relationship of art to society, bearing in mind the irreducible tension between the autonomy and heteronomy of the one in relation to the other. To do so, we analyze the main arguments about this dialectical relationship in two distinct moments of philosophical reflection on the subject. First, we argue for a degree of autonomy of art in relation not only to the social context that produces it but also with respect to the moral values that are taught through it, as found in the critique of Nietzsche in his interpretation of classical tragedy, principally in his The Birth of Tragedy. We then draw a parallel between this argumentation and that of Adorno on the exploitation and marketing of contemporary art. In this context, we also discuss Nietzsche's critique of the cultural productions of Greece in the fourth century BC, and contextualize them in relation to contemporary aesthetic phenomena. (shrink)

The fate of cellular RNAs is largely dependent on their structural conformation, which determines the assembly of ribonucleoprotein (RNP) complexes. Consequently, RNA‐binding proteins (RBPs) play a pivotal role in the lifespan of RNAs. The advent of highly sensitive in cellulo approaches for studying RNPs reveals the presence of unprecedented RNA‐binding domains (RBDs). Likewise, the diversity of the RNA targets associated with a given RBP increases the code of RNA–protein interactions. Increasing evidence highlights the biological relevance of RNA conformation for recognition (...) by specific RBPs and how this mutual interaction affects translation control. In particular, noncanonical RBDs present in proteins such as Gemin5, Roquin‐1, Staufen, and eIF3 eventually determine translation of selective targets. Collectively, recent studies on RBPs interacting with RNA in a structure‐dependent manner unveil new pathways for gene expression regulation, reinforcing the pivotal role of RNP complexes in genome decoding. (shrink)

Los Servicios de Inteligencia en la fase que se extiende desde el final de la guerra civil hasta el fallecimiento del General Franco sufrieron, como es lógico, las vicisitudes propias de una organización que estuvo sometida, en un principio, a la situación mundial, derivada del desarrollo de la Segunda Guerra Mundial y ala precariedad de medios, humanos y materiales, fundamentalmente hasta la década de los años 70, que se derivaban de la propia situación nacional. En sus orígenes estuvieron obligados a (...) mantener una estructura similar a la existente durante la guerra civil, como consecuencia del desarrollo de la guerra en Europa…. (shrink)

Hospitality can be considered a key institution in the social relationships in the ancient Mediterranean. To identify the people involved in a hospitality agreement, in certain contexts small objects were used in a similar way to a password, which the Greeks called symbolon and the Romans tessera hospitalis. We know how the latter were used thanks to Plautus' Poenulus. At least 64 pieces are currently known which may be identified as tesserae hospitales. All come from the Western Mediterranean. The majority (...) contain brief inscriptions, written in Etruscan, Latin, Greek, or Celtiberian. They share a series of common features, which impart a clear family resemblance beyond geographic, cultural, or linguistic borders. (shrink)

This essay explores the intersection of the reality of journey, present in the lives of so many recent immigrant Latinos/as, with the theme of journey as found in the Fourth Gospel. This exploration raises questions about what it means to live in the United States as a Latino/a as well as questions about the role of the plot of the Fourth Gospel in negotiating bicultural relations.

Trata de uma leitura do papel da tecnociência no que tange ao esvaziamento ético com o qual nos deparamos. Para tanto, vale-se das abordagens feitas por Jürgen Habermas e Hans Jonas. Neste sentido, opera com alguns conceitos fundamentais de ambos os teóricos, no que se refere ao tema posto. Do primeiro filósofo refletir-se-á acerca do esvaziamento dos significados do mundo da vida face ao caráter instrumentalizador que a razão assumiu após o iluminismo. Do segundo, analisar- se-á o vácuo ético operante (...) diante do poder que foi outorgado ao homem pela tecnociência. (shrink)

According to the usual interpretation, Plato's last dialogue, the Laws, indicates a substantial change in his political thought, namely the defence of the Rule of Law as the best possible political order. Therefore, he has been considered the first representative of this central concept for the modern State. The present paper points to the radical differences between Plato'sconception and the contemporary understanding of the Rule of Law. It also explains his interpretation of the function of the law in a well-ordered (...) State and to the opposition of his view to ourcontemporary doctrine of democracy. (shrink)

SíNTESE - Partindo de um exame mais cuidadoso e de uma leitura menos linear das fontes, o artigo procura mostrar que as concepções adornianas a respeito da arte na era da técnica, embora críticas, revelam uma abertura dialética, não se deixando prender a dogmas e preconceitos, conforme pretendem seus adversários.

In this article Jason Brennan’s arguments about the moral duties relating to our practice of voting are examined. These arguments provide an epistocratic approach of politics and present a conception of abstention at four levels: abstention as a personal choice, as a moral responsibility, as a duty legally enforceable and as an obligation decided by lot. The contrast with John Stuart Mill’s positions helps to highlight the postdemocratic ambivalences and the latent paternalism behind Brennan’s rejection of massive voting and electoral (...) democracy. A deliberative, Millian-inspired understanding of abstention also allows questioning the assumption in Brennan’s successive proposals that there is no significant loss in overlooking the political valence of qualified abstention. (shrink)

In this paper, I engage in the debate on the definition of the cyborg. I identify the two defining components of the traditional definition of the cyborg: the symbiotic relationship between human nature and technology; and the embodiment of a superhuman or inhuman feature or ability. Then, I trace these two components in the scholarly debate on the cyborg. To conclude, I explore the role the scholarly view of the cyborg plays in the debate on cyborg-athletes in the philosophy of (...) sport. (shrink)

Este artigo problematiza, sob o ponto de vista teórico da Análise do Discurso francesa, por que, em algumas regiões do Nordeste brasileiro, há quem evite pronunciar a palavra macaco e opte por usar em seu lugar outras palavras, tais como dezessete. A hipótese defendida é a de que essa prática cultural-discursiva, entendida aqui como uma forma de interdição, ocorre basicamente em regiões sertanejas onde a memória do cangaço é ainda marcadamente diluída no cotidiano. A partir da análise de discursos presentes (...) no dia a dia, este artigo pretende contribuir para uma compreensão mais acurada de uma particularidade sociocultural brasileira. (shrink)

Se trata de la obra más completa hasta hoy sobre la historia de las ideas filosóficas en Argentina. El primer volumen cubre desde la colonia hasta los comienzos de la superación del positivismo. El segundo se dedica al siglo veinte, desde 1910 a 1943, y considera que los temas capitales de esta etapa son la vida y los valores, notándose una relación menos estrecha, por lo menos en lo aparente, entre el pensamiento filosófico y la vida político-social. Sería altamente recomendable (...) que el autor completara este panorama hasta fines del siglo que concluye"--Handbook of Latin American Studies, v. 58. (shrink)

This paper sets forth a familiar theme, that science essentially consists of two interdependent episodes, one imaginative, the other critical. Hypotheses and other imaginative conjectures are the initial stage of scientific inquiry because they provide the incentive to seek the truth and a clue as to where to find it. But scientific conjectures must be subject to critical examination and empirical testing. There is a dialogue between the two episodes; observations made to test a hypothesis are the inspiration for new (...) conjectures. Inductive generalizations may also inspire hypotheses, but cannot validate them. A hypothesis is empirically tested by ascertaining whether or not predictions about the world of experience deduced from the hypothesis agree with what is actually observed. This has been appropriately considered the 'criterion of demarcation' that distinguishes science from other knowledge. But scientific hypotheses must satisfy other tests as well, e.g., whether they have explanatory value and further understanding. I briefly explore such issues as verifiability and falsifiability, empirical content and truthfulness, contingency and certainty, fact and theory, error and fraud. Science like any human activity is subject to error and to the foibles and other failings of human beings. But severe attempts of empirical falsification and other trials yield knowledge that stands the test of time and provides a foothold for further knowledge. Moreover, scientists have developed social mechanisms, such as peer review and publication, to evaluate their work. Because the research of scientists depends on the validity of previous knowledge, it is of great consequence that they discern valid from invalid knowledge and thus scientists are inclined to transcend ideology, nationality, friendship, monetary interest and other prejudices when the mettle of scientific knowledge is at stake. I use historical examples to illustrate some relevant aspects of scientific practice: its success (Mendel), misrepresentation (Darwin), ideological abuse (Lysenko), arrogant violation of the requirement of testing (Koch), theory replacement (Priestly and Lavoisier, Newton and Einstein), and the indispensability of context (Oswald Avery and Alfred Wegener). (shrink)

The "antecedents, continuity and projections" of Neoplatonism are revised, priming the individual and communitary intertextuality, as the medium of study most valid for a train of thought that gives priority to the doctrinal body rather than to the individual. In this way are seen the diverse neoplatonic systems (Greek, Byzantine, Gnostic...) although it is also noted that, when this doctrinal aspect is weakened, Neoplatonism may externally influence the doctrines and philosophical authors who are very different from its spirit (Christians, Jews, (...) Islamic, renaissentists, modern and contemporary). (shrink)