I propose to dissolve the distinction between “rustic” and “urbane” interpretations of Sextus Empiricus’ account of Pyrrhonian assent to appearances. On the traditional picture, the “rustic” takes the skeptic to have no beliefs while the “urbane” takes the skeptic to have some “everyday” beliefs. I examine the distinction in two forms. First, in the original suite of papers by Frede, Burnyeat, and Barnes, I find that aside from a few differences in English terminology choice, the three authors substantially agree on (...) the interpretation of assent to appearances. Second, turning to the revised distinction proposed by Fine, I find that the two supposedly divergent interpretations give us pictures of the Pyrrhonist indistinguishable from each other on the basis of the skeptic’s actions or assent. The distinction dissolved, I propose a unified interpretation that expresses what I find to be the ultimate agreement between the two supposedly different camps. Finally, I turn to the question of the skeptical life and use this unified interpretation to argue that both an everyday life and an unconventional one are equally consistent with Pyrrhonian practice. (shrink)

Aenesidemus, the (re-)founder of Pyrrhonian skepticism, is usually said to have begun his career by breaking away from the Academy. This assertion rests on the word “συναιρεσιώτῃ” as it appears in Photius’ summary of Aenesidemus’ Pyrrhonian Discourses. I argue that Photius’ probable understanding of the Academy’s history undermines this traditional reading. I then examine the evidence external to Photius and conclude that it also speaks against the traditional narrative.

Drawing on a landscape analysis of existing data-sharing initiatives, in-depth interviews with expert stakeholders, and public deliberations with community advisory panels across the U.S., we describe features of the evolving medical information commons. We identify participant-centricity and trustworthiness as the most important features of an MIC and discuss the implications for those seeking to create a sustainable, useful, and widely available collection of linked resources for research and other purposes.

Popper's paradox of ideal evidence has long been viewed as a telling criticism of Keynes's logical theory of probability and its associated concept of the weight of argument. This paper shows that a simple addition to Keynes's definitions of irrelevance enables his theory to elude the paradox with ease. The modified definition draws on ideas already present in Keynes's Treatise on Probability (1973). As a consequence, relevant evidence and the weight of argument may increase, even when new evidence leaves the (...) probability unaltered. (shrink)

In 1886, Nietzsche wrote: ‘I am still waiting for a philosophical doctor in the extraordinary sense of the term’: a doctor who pursues not truth, but an exceptional kind of health. Nietzsche's will to health, his theory of drive organisation, and his insistence that the philosopher put himself at risk, all work together in his overall project, which consists of taking up the very role of the highly revalued physician for whom he is waiting. Deleuze and Guattari engage this same (...) task of a revalued doctoring in the Capitalisme et Schizophrénie books, attacking the disease of oedipality and providing instructions for the deorganisation of the organism as self-cure. Offering tips on this radical treatment, they employ the figure of the hypochondriac to show how it can fail. Both Nietzsche and Deleuze and Guattari perform a revaluation of health as a condition of chronic critique, a condition that wraps itself around illness to keep itself critical. (shrink)

The Crying of Lot 49 is widely recognized as a significant contemporary work that frames the desire for meaning and the quest for knowledge within the social and political contexts of the '50s and '60s in America. In the introduction to this collection of original essays on Thomas Pynchon's important novel, Patrick O'Donnell discusses the background and critical reception of the novel. Further essays by five experts on contemporary literature examine the novel's "semiotic regime" or the way in which it (...) organizes signs; the comparison of postmodernist Pynchon and the influential South American writer, Jorge Luis Borges; metaphor in the novel; the novel's narrative strategies; and the novel within the cultural contexts of American Puritanism and the Beat movement. Together, these essays provide an examination of the novel within its literary, historical, and scientific contexts. (shrink)

It is difficult to respond creatively to humiliation, affliction, degradation, or shame, just as it is difficult to respond creatively to the experience of undergoing or inflicting violence. In this article Aislinn O'Donnell argues that if we are to think about how to address gun violence — including mass shootings — in schools, then we need to talk about violence inside and outside schools. Honest, and even difficult, conversations about violence and vulnerability can take place in schools, and there are (...) ways of working with curricula and student voice that can allow for this. If pedagogy is to play a role in reorienting responses to violence and vulnerability, discussion of equivocal and ambivalent responses to corporeal vulnerability, and of histories and genealogies of violence, must be invited. We need to acknowledge that we do not have, and we may well never have, a world without violence. Drawing upon the experience of teaching philosophy in nontraditional learning environments, including prison, O'Donnell argues for an approach to pedagogy and curricula that invites difficult conversations about the complexity of violence. (shrink)

ABSTRACT In this article the Irish harp tradition is re-configured as a space consisting of visual and sonic dimensions. The visual dimension of the Irish harp space incorporates the employment of the instrument in contemporary iconography; the sonic dimension includes the employment of the instrument as a metaphor in contemporary literature and songs. By employing Bloch’s concept of surplus and tracing the path of the Irish harp from its earliest employment in Christian iconography, its prominence as an icon of colonial (...) and Ascendancy rule, and finally its utilisation as an utopian tool to inspire members of the Volunteer and United Irish movements in the late eighteenth century, I identify how the accumulation of centuries of utopian surplus resulted in the creation of an utopian icon that had the capacity to inspire a generation of Irish men and women to critique the prevailing social and political order in the eighteenth century. (shrink)

The title of this congress begins with the word “identity”. It also includes the word “reciprocity,” which indicates a form of relationship and finally, “gift of self”. This would lead us to conclude that the identity of the human person has something to do with reciprocity and that reciprocity involves giving of oneself to others. This talk will attempt to shed light on how the concept of gender might in some way be incorporated into these three concepts. Defining what constitutes (...) the identity of the human person has been explored, and attempts to define it have been made by every major theorist in the field of psychology. At a previous Psychology and Communion congress one of the talks spoke of loving and being loved in return as the basic foundation of human identity. In that presentation we find the following observation: “The identity of the human person can be compared to the identity of a book: we know where and when it was printed; but the author is certainly not the publishing house, nor is the typesetter who prepared the text…The same is true for us human beings: we know the time and date of birth. But who is author?”. We ask ourselves, therefore: what lies at the core of the identity of this being who is born at a certain time on a certain date? Before proceeding, I think it is important to note that the basic idea regarding the identity of the human person, as we have defined and understood it from the inception of psychology and communion and explored in previous encounters, remains unchanged. I will use a quote of Chiara Lubich here that perhaps many of you know but which can serve the purpose of laying the foundation for what follows: Human beings are “ all equal but distinct. To each person [God] gave his own beauty so that they would be desirable and lovable by others; and so that in love they would be recomposed into the One who had created them with his Light, which is Himself.” Now we ask ourselves: What exactly is this “beauty” that Chiara is speaking of? What are the components, if you will, of our identity that makes us “… desirable and lovable by others…”? (shrink)

pt. 1. Modernity, sociology and the structure/agency debate -- pt. 2. Critical theory; structuration theory; critical realism; and identity theory -- pt. 3. Structure/agency theories applied -- pt. 4. Network theory, globalisation theory, hegemony -- pt. 5. Conclusion/continuation.

Since the turn of the millennium, theologians and secular scholars of religion have increasingly begun exploring the relationship between transhumanism and religion. However, analyses of anti-transhumanist apocalypticisms are still rare, and those that exist are situated mainly among broader explorations of religious and secular bioconservatism. This article addresses this lack of specificity by drawing analyses of transhumanism and religion into dialogue with explorations of contemporary demonology through a close study of the beliefs of the evangelical conspiracist Thomas Horn and the (...) anti-transhumanist milieu around him. Exploring the milieu's multifaceted demonology of the secular world in light of genealogies of religion and secularity, the article situates Horn's demonology as one attempt to negotiate these genealogies, using what Sean McCloud terms a “‘supernatural’ hermeneutics of suspicion” that sees spiritual forces as the structural base of reality. It argues that, while fringe, milieus like Horn's illuminate broader cultural tensions and genealogical relations surrounding the place of religion in a secular world. (shrink)

(2000). Of loaded dice and heated arguments: Putting the Hansen?Michaels global warming debate in context. Social Epistemology: Vol. 14, No. 2-3, pp. 109-127.

Clamp loaders are pentameric AAA+ assemblies that use ATP to open and close circular DNA sliding clamps around DNA. Clamp loaders show homology in all organisms, from bacteria to human. The eukaryotic PCNA clamp is loaded onto 3′ primed DNA by the replication factor C (RFC) hetero‐pentameric clamp loader. Eukaryotes also have three alternative RFC‐like clamp loaders (RLCs) in which the Rfc1 subunit is substituted by another protein. One of these is the yeast Rad24‐RFC (Rad17‐RFC in human) that loads a (...) 9‐1‐1 heterotrimer clamp onto a recessed 5′ end of DNA. Recent structural studies of Rad24‐RFC have discovered an unexpected 5′ DNA binding site on the outside of the clamp loader and reveal how a 5′ end can be utilized for loading the 9‐1‐1 clamp onto DNA. In light of these results, new studies reveal that RFC also contains a 5′ DNA binding site, which functions in gap repair. These studies also reveal many new features of clamp loaders. As reviewed herein, these recent studies together have transformed our view of the clamp loader mechanism. (shrink)

James questions the validity of the very tentative statement made in the final sentence of our paper. Our claim concerned the proportion of twins in Britain in the 1990s that might have arisen through subfertility treatment and was linked to the suggestion that the natural twinning rate might still be in decline. If this were true, we, like James, would regard that prospect with concern.

The project of this paper is to deliver a semantics for a broad subset of bare plural generics about racial kinds, a class which I will dub 'Type C generics.' Examples include 'Blacks are criminal' and 'Muslims are terrorists.' Type C generics have two interesting features. First, they link racial kinds with ​ socially perspectival predicates ​ (SPPs). SPPs lead interpreters to treat the relationship between kinds and predicates in generic constructions as nomic or non-accidental. Moreover, in computing their content, (...) interpreters must make implicit reference to socially privileged​ ​ perspectives which are treated as authoritative about whether a given object fits into the extension of the predicate. Such deference grants these authorities influence over both the conventional meaning of these terms and over the nature of the ​ objects ​ in the social ontology that these terms purport to describe, much the way a baseball umpire is authoritative over the meaning and metaphysics of 'strike'/​ strike ​. Second, terms like 'criminal' and 'terrorist' receive default ​ racialized ​ interpretations in which these terms conventionally token racial or ethnic identities. I show that neither of these features can be explained by Sarah-Jane Leslie's influential 'weak semantics' for generics, and show how my own 'socially perspectival semantics' fares better on both counts. Finally, I give an analysis of 'Blacks are criminal' which explores the semantic mechanisms that underlie default racialized interpretations. (shrink)

_Antisemitism, Islamophobia, and Interreligious Hermeneutics: Ways of Seeing the Religious Other_ examines the hermeneutics of interreligious encounter, investigating the implicit judgments of Judaism and Islam that often arise in contexts of conflict.

Over the last decade, there has been a considerable expansion of mindfulness programmes into a number of different domains of contemporary life, such as corporations, schools, hospitals and even the military. Understanding the reasons for this phenomenon involves, I argue, reflecting upon the nature of contemporary capitalism and mapping the complexity of navigating new digital technologies that make multiple and accelerated solicitations upon attention and our affective lives. Whilst acknowledging the benefits of mindfulness practice, this article argues that it is (...) equally important to attend to the ethical framework that gives orientation to these practices and the outer conditions that shape lived daily experience, such as school or work environments. I suggest that the well-meaning efforts to secularise mindfulness, provide scientific evidence for its effectiveness, and introduce it to wider publics may have served to impoverish the rich contribution that practices of mindfulness, situated within a broader ethical framework, can make to human lives, and arguably contribute to the educational endeavour. For example, the emphasis on transforming inner conditions of students’ lives can lead to the neglect of outer conditions, such as structural inequality, or unhealthy and exploitative work practices. This can result in practices that privilege individual wellbeing over compassion and concern for the happiness of others, providing a buffer against loving attention to the world and others. Instead, I ask how mindfulness in educational settings could come to be viewed in a different light if we reflect upon the ways in which school environments and curricula can promote mindfulness, awareness, sensitive inquiry, and contemplative practices through the day, rather than offering it as a discrete intervention focused on the self and wellbeing. (shrink)

Pessimists hold that human life is fundamentally a condition of suffering which cannot attain transcendent meaning. According to pessimistic nihilism, life’s lack of transcendent meaning gives us reason to regret our existence. Life-affirming nihilism insists that we can and should affirm life in the absence of transcendent meaning. Yet both of these strains struggle to articulate what practical reasons might compel us to regret or affirm our inability to transcend the immanent conditions of the human predicament in the first place. (...) I suggest that we catch sight of these practical reasons when we shift our attention from the value of transcendent meaning to the desire for temporal transcendence expressed by strong attachments such aslove and devotion. In short, we want the things we love to last forever, and they can’t. This makes human life tragic, but it does not settle the question of what sort of meaning it might have or lack. (shrink)