Finding that an avian herpesvirus can cause atherosclerosis in chickens prompted studies of human herpesviruses in human atherosclerosis. Antigens and nucleic acid sequences of cytomegalovirus (CMV), a widespread member of the herpesvirus family, were found in arterial lesions in human atherosclerosis, but infectious virus has not been observed. In atherosclerosis patients, high levels of CMV antibodies are present, suggesting the presence of virus that had been activated from a latent state. Atherosclerosis also develops in immunesuppressed heart transplant patients infected with (...) CMV. The properties of CMV are consistent with its involvement at several levels of the atherogenic process. If this concept is correct, immunization with a CMV vaccine should prevent CMV infection and atherosclerosis. (shrink)

In the free will literature, some compatibilists and some incompatibilists claim that their views best capture ordinary intuitions concerning free will and moral responsibility. One goal of researchers working in the field of experimental philosophy has been to probe ordinary intuitions in a controlled and systematic way to help resolve these kinds of intuitional stalemates. We contribute to this debate by presenting new data about folk intuitions concerning freedom and responsibility that correct for some of the shortcomings of previous studies. (...) These studies also illustrate some problems that pertain to all of the studies that have been run thus far. (shrink)

This essay explores the importance of Donner le temps II within the context of Derrida’s writings on Heidegger and the gift. In the first section of the essay, I situate the publication of the latter half of Derrida’s 1978–79 seminar against his writings on the gift generally, beginning in 1968 and ending in 2000. In the second section, I explain how the second volume of Donner le temps relates to the first. In the final three sections of the paper, I (...) focus on three prominent topics of the seminar, so as to show how they impact our previous understanding of major aspects of Derrida’s thought: first, the Heideggerian thinking of the es gibt, as it relates to the gift’s unconditionality. Second, the problematic of the Kunstwerk, as it informs Derrida’s thinking of récit. Third, the problem of Dichtung, as it is linked to the poématique. (shrink)

Sommers (2010) argues that experimental philosophers of free will have largely been asking the wrong question – the question whether philosophically naïve individuals think that free will and moral responsibility are compatible with determinism. The present studies begin to alleviate this concern by testing the intuitive plausibility of Pereboom’s (2001) four case argument. The general pattern of responses from two experiments does not support Pereboom’s predictions. Moreover, those who were high in the personality trait emotional stability tended to judge that (...) manipulated agents were more free and morally responsible compared to individuals low in emotional stability. (shrink)

Precision testing of the quantum electrodynamics (QED) and the standard model provides some of the most secure knowledge in the history of physics. These tests can also be used to constrain and search for new physics going beyond the standard model. We examine the evidential structure of relationships between theoretical predictions from QED, precision measurements of these phenomena, and the indirect determination of the fine structure constant. We argue that "pure QED" is no longer sufficient to predict the electron's anomalous (...) magnetic moment, and that standard model effects are needed. The details relevant to low-energy QED are robust against future theory change. (shrink)

The past ten years have seen multiple attempts to estimate the relation between the global personality trait extraversion and compatibilist free will judgments. Here, we contribute to that line of research by conducting a meta-analysis of 17 published and eight unpublished studies (N = 2,811) estimating that relation. Overall, the mean effect size was modest but remarkably robust across materials, locations, and labs (z =.19, 95% CI.15-.24, p <.001). No significant publication bias was detected in the studies (t (23) = (...) 1.88, p =.07). While there was no significant heterogeneity in the studies (Q (24) = 34.42, p =.08, I2 = 26.05), a moderator analysis suggested that the effect is strongest in cases that contain highly affective actions (e.g., murder) (z =.22, 95% CI.17-.28, p <.001) and weakest in cases that contain actions with low affect (e.g., asking whether free will is compatible with determinism) (z =.09, 95% CI -.05-.23, p =.22). The meta-analysis provides additional evidence that extraversion is related to compatibilist free will judgments and helps to identify opportunities to discover boundary conditions and more proximal causal mechanisms for the relation. The results of the meta-analysis also have implications for informed decision making. (shrink)

ABSTRACT Recruitment into the scientific community is one oft-stated goal of science education—in the post-Sputnik United States, for example—but this obscures the fact that science textbooks are often read by people who will never be scientists. It cannot be presupposed that science textbooks for younger audiences, students in primary and secondary schools, function in this way. For this reason, precollegiate-level science textbooks are sometimes discussed as a subset of literature popularizing science. The high school science classroom and the textbook are (...) forums for exposing the public to science. The role of governments and educational institutions in regulating the consumption of these texts not only determines which books are used; it influences how they are written, read, and deemed authoritative. Therefore such science textbooks should not be seen as (at best) the disjunction of texts-for-training and books-for-popularization. A changing sense of what “textbooks” are compels a different understanding of their use in the history of science. (shrink)

In this paper I formulate Minimal Requirements for Candidate Predictions in quantum field theories, inspired by viewing the standard model as an effective field theory. I then survey standard effective field theory regularization procedures, to see if the vacuum expectation value of energy density ) is a quantity that meets these requirements. The verdict is negative, leading to the conclusion that \ is not a physically significant quantity in the standard model. Rigorous extensions of flat space quantum field theory eliminate (...) \ from their conceptual framework, indicating that it lacks physical significance in the framework of quantum field theory more broadly. This result has consequences for problems in cosmology and quantum gravity, as it suggests that the correct solution to the cosmological constant problem involves a revision of the vacuum concept within quantum field theory. (shrink)

Many areas of frontier physics are confronted with the crisis of a lack of accessible, direct evidence. As a result, direct model building has failed to lead to any new empirical discoveries. In this paper I argue that these areas of frontier physics have developed common methods for turning precision measurements of known quantities into potential evidence for anomalies hinting at new physics. This method of framework generalization has arisen as a sort of model-independent method for generalizing beyond known physics (...) and organizing experimental searches. I argue that this method is well-justified given the current epistemic landscape, and that theory construction in general is much broader than simply building new dynamical models. (shrink)

This paper proposes new semantics for propositional dynamic logic (PDL), replacing the standard relational semantics. Under these new semantics, program execution is represented as fundamentally deterministic (i.e., functional), while nondeterminism emerges as an epistemic relationship between the agent and the system: intuitively, the nondeterministic outcomes of a given process are precisely those that cannot be ruled out in advance. We formalize these notions using topology and the framework of dynamic topological logic (DTL) (Kremer and Mints in Ann Pure Appl Logic (...) 131:133–158, 2005). We show that DTL can be used to interpret the language of PDL in a manner that captures the intuition above, and moreover that continuous functions in this setting correspond exactly to deterministic processes. We also prove that certain axiomatizations of PDL remain sound and complete with respect to the corresponding classes of dynamic topological models. Finally, we extend the framework to incorporate knowledge using the machinery of subset space logic (Dabrowski et al. in Ann Pure Appl Logic 78:73–110, 1996), and show that the topological interpretation of public announcements as given in Bjorndahl (in: van Ditmarsch and Sandu (eds) Jaakko Hintikka on knowledge and game theoretical semantics, outstanding contributions to Logic, vol 12, Springer, 2018) coincides exactly with a natural interpretation of test programs. (shrink)

We present evidence indicating new individual differences with people's intuitions about the relation of determinism to freedom and moral responsibility. We analysed participants' written explanations of why a person acted. Participants offered one of either 'decision' or 'causal' based explanations of behaviours in some paradigmatic cases. Those who gave causal explanations tended to have more incompatibilist intuitions than those who gave decision explanations. Importantly, the affective content of a scenario influenced the type of explanation given. Scenarios containing highly affective actions (...) (e.g. murder) tended to generate more decision explanations than scenarios with low affective content (e.g. cheating on taxes). These results give important clues about the proximal processes generating some intuitions about free will and moral responsibility. (shrink)

INSTITUTES OF Moral Philosophy. INTRODUCTION. » SECTION I. Of Knoivledge in general. * AL L knowledge is either of particular facts, or of general rules. ...

We review evidence showing that disagreement in folk and expert philosophical intuitions can be predicted by global, heritable personality traits. The review focuses on recent studies of intuitions about free will, ethics, and intentional action. These findings are philosophically important because they suggest that while some projects cannot be done, other projects must take individual differences in philosophical character into account. But care needs to be taken when interpreting the implications of these individual differences. We illustrate one way that these (...) differences have been abused. We then illustrate two ways that these findings can be legitimately used to help illuminate philosophical issues. Given the large and readily available body of evidence, neglect of persistent and predictable philosophical differences is irresponsible. (shrink)

Given its non-invasive nature, there is increasing interest in the use of transcutaneous vagus nerve stimulation across basic, translational and clinical research. Contemporaneously, tVNS can be achieved by stimulating either the auricular branch or the cervical bundle of the vagus nerve, referred to as transcutaneous auricular vagus nerve stimulation and transcutaneous cervical VNS, respectively. In order to advance the field in a systematic manner, studies using these technologies need to adequately report sufficient methodological detail to enable comparison of results between (...) studies, replication of studies, as well as enhancing study participant safety. We systematically reviewed the existing tVNS literature to evaluate current reporting practices. Based on this review, and consensus among participating authors, we propose a set of minimal reporting items to guide future tVNS studies. The suggested items address specific technical aspects of the device and stimulation parameters. We also cover general recommendations including inclusion and exclusion criteria for participants, outcome parameters and the detailed reporting of side effects. Furthermore, we review strategies used to identify the optimal stimulation parameters for a given research setting and summarize ongoing developments in animal research with potential implications for the application of tVNS in humans. Finally, we discuss the potential of tVNS in future research as well as the associated challenges across several disciplines in research and clinical practice. (shrink)

Jennifer Lackey presents a puzzle to which she argues there is no current solution. Lackey's claim is that testimonial knowledge can have something conspicuously wrong with it and still be knowledge. Testimonial knowledge can be ‘deficient’. Given that knowledge is a normative category, that it describes what it is for a belief to go right, there is a puzzle that comes with accounting for how a testimonial belief could be knowledge and yet go wrong in the ways Lackey has in (...) mind. In this paper, I argue that the deficiency is one of teamwork, and that Lackey's puzzle offers one a window into the respect in which testimony is a kind of team achievement. (shrink)

Experimental philosophy is a new approach to philosophy that incorporates the experimental methodologies of psychology, behavioral economics, and sociology. Experimental philosophers generally maintain that, in addition to traditional philosophical practices, these ways of gathering evidence can be instrumental in shedding light on philosophically important issues. Rather than relying on their own intuitions about specific cases, experimental philosophers perform systematic experiments to determine what intuitions people have about those cases. These intuitions are then used as evidence. In this context, four main (...) approaches to experimental philosophy are introduced, a sample of experimental philosophy’s results is offered, and some of the philosophical importance of those results is explained. (shrink)

The purpose of this paper is to draw attention to the normative role of conventions in sports. However, the approach I have in mind does not dispatch the theory of interpretivism. What I offer is a synthesis that aims to show how interpretivism works in concert with – and relies heavily on – conventions. To make this point, I will argue that historical, cultural, and even simple preferential needs and desires help to determine what counts as athletic ‘excellence’ in sports.

ABSTRACTThis article argues that there is a just cause for war to prevent the future hazards of anthropogenic climate change even if, because of what is known as the Non-Identity Problem, that caus...

In discussing the origins of the antievolution movement in American high schools within the framework of science and religion, much is overlooked about the influence of educational trends in shaping this phenomenon. This was especially true in the years before the 1925 Scopes trial, the beginnings of the school antievolution movement. There was no sudden realization in the 1920's – sixty years after the "Origin of Species" was published – that Darwinism conflicted with the Bible, but until evolution was being (...) taught in the high schools, there was no impetus to outlaw it. The creation of "civic biology" curricula in the late 1910's and early 20's, spearheaded by a close-knit community of textbook authors, brought evolution into the high school classroom as part of a complete reshaping of "biology" as a school subject. It also incorporated progressive ideologies about the purposes of compulsory public education in shaping society, and civic biology was fundamentally focused on the applications of the life sciences to human life. Antievolution legislation was part of a broader response to the ideologies of the new biology field, and was a reaction not only to the content of the new subject, but to the increasingly centralized control and regulation of education. Viewing the early school antievolution movement through the science-religion conflict is an artifact of the Scopes trial's re-creation of its origins. What largely caused support for the school antievolution movement in the South and particularly Tennessee were concerns over public education, which biology came to epitomize. (shrink)

In two experiments, we demonstrate that intentional action intuitions vary as a function of whether one brings about or observes an event. In experiment 1a (N?=?38), participants were less likely to judge that they intended (M?=?2.53, 7 point scale) or intentionally (M?=?2.67) brought about a harmful event compared to intention (M?=?4.16) and intentionality (M?=?4.11) judgments made about somebody else. Experiments 1b and 1c confirmed and extended this pattern of actor-observer differences. Experiment 2 suggested that these actor-observer differences are not likely (...) to occur when participants are asked to ?imagine? being an actor. We argue that these results challenge the substantial philosophical and empirical reliance on hypothetical thought examples about intentional action. Our data offer new and necessary methodological avenues for understanding folk intentional action intuitions. (shrink)

I provide an account of precision testing in particle physics that makes a virtue of theory-ladenness in experiments. Combining recent work on the philosophy of experimentation with a broader view of the scientific process allows one to understand that the most precise and secure knowledge produced in a mature science cannot be achieved in a theory-independent fashion. I discuss precision tests of the muon’s magnetic moment and effective field theory as a means to repurpose precision tests for exploratory purposes.

Kant’s deontology is often seen as a rival to virtue ethics. This chapter argues, however, that while there may be differences between Kant’s and Aristotle’s conceptions virtue (for instance, a virtuous person, in Kant’s view, may be destitute and unhappy, fail to cultivate certain emotions and sentiments, etc.), virtue is central to Kant’s ethics. The key problem is whether there is a Kantian account of virtue compatible with Kant’s view of free will. Kant held that having virtue means having a (...) will that is both good and stable. So to cultivate virtue means to cultivate a stable will. But the idea of character cultivation seems to run counter to Kant’s view of freedom, since for Kant, people are always free to choose how to act. This chapter puts forth a novel proposal for solving this problem, one which has to do with the limits on self-knowledge. (shrink)

Rather than being in inherent conflict with religion or operating on planes that do not intersect, the cognitive science of religion (CSR) can be used to renovate a religious understanding of the world. CSR allows one to reshape the perspectives of Aquinas and Calvin on the natural knowledge of God. The Christian tradition affirms that all human beings have available to them some knowledge of God. This claim has empirical import and thus invites scientific investigation and clarification. A CSR-inspired lens (...) allows one’s theological reflections to move from paradigms that focus on the cognitive reach of a domain-general power of human thought to a paradigm focused on different ways of relating to another person. The case study of the natural knowledge of God presented here models a productive way of relating CSR and religious perspectives from within a faith tradition. (shrink)

It is commonly claimed that fully virtuous individuals cannot be ignorant and that everyday intuitions support this fact. Others maintain that there are virtues of ignorance and most people recognize them. Both views cannot be correct. We report evidence from three experiments suggesting that ignorance does not rule out folk attributions of virtue. Additionally, results show that many of these judgments can be predicted by one’s emotional stability—a heritable personality trait. We argue that these results are philosophically important for the (...) study of virtue and we discuss some of the ways individual differences may inform and facilitate current debates in ethics. We close with a cautionary argument detailing the risks of discounting some intuitions simply because they are associated with seemingly less desirable personality traits. (shrink)

Appeals to “being on the right side of history” or accusations of being on the wrong side of history are increasingly common on social media, in the media proper, and in the rhetoric of politics. One might well wonder, though, what the value is of invoking history in this manner. Is declaring who is on what side of history merely dramatic shorthand for one's being right and one's opponents wrong? Or is there something more to it than that? In this (...) paper, I argue that an appeal to being on the right side of history is best construed as an invocation of higher-order evidence. I do not deny that there are purely rhetorical, non-evidential uses of the right and wrong side of history, but the phrase can be construed in a more substantive manner. I use work on virtual epistemic elections to model these appeals to history. Zeroing in on the kind of higher-order evidence invoked helps us clarify the criterion for better or worse, more or less convincing appeals to it. (shrink)

Five experiments suggested that everyday free will and moral responsibility judgments about some hypothetical thought examples differed from free will and moral responsibility judgments about the actual world. Experiment 1 (N = 106) showed that free will intuitions about the actual world measured by the FAD-Plus poorly predicted free will intuitions about a hypothetical person performing a determined action (r = .13). Experiments 2–5 replicated this result and found the relations between actual free will judgments and free will judgments about (...) hypothetical determined or fated actions (rs = .22–.35) were much smaller than the differences between them (ηp2 = .2–.55). These results put some pressure on theoretical accounts of everyday intuitions about freedom and moral responsibility. (shrink)

The computable Lipschitz reducibility was introduced by Downey, Hirschfeldt and LaForte under the name of strong weak truth-table reducibility [6]). This reducibility measures both the relative randomness and the relative computational power of real numbers. This paper proves that the computable Lipschitz degrees of computably enumerable sets are not dense. An immediate corollary is that the Solovay degrees of strongly c.e. reals are not dense. There are similarities to Barmpalias and Lewis’ proof that the identity bounded Turing degrees of c.e. (...) sets are not dense [2]), however the problem for the computable Lipschitz degrees is more complex. (shrink)

Recent research on the semantics and pragmatics of slurs has offered insight into several important facts concerning their meaning and use. However, prior work has unfortunately been restricted primarily to considerations of slurs that typically target females, homosexuals, and African Americans. This is problematic because such a narrowly focused attention to slurs in prior work has left theorizing of how slurs generally function relatively uninformed by facts of actual language use. As a result, theoretical accounts of slurs that have so (...) far been proposed have largely failed to accurately reflect actual usage, account for the empirical findings about slurs and general pejoratives from the social sciences, and offer any informative predictions to help guide future research. At this time more empirically oriented homework on the variety of ways that different slurs have been used in different cases would be helpful for theorists to consider so that they can proceed to develop more nuanced and empirically informed theories about slurs, their usage, and their effects. Accordingly, since no account of slurs for Italian Americans has so far been offered, this article provides a systematic and empirically informed analysis of slurs for Italian Americans that accounts for both their derogatory and appropriative use. Further, this article demonstrates that the family resemblance account of slurs maintained here has major advantages over previous accounts insofar as it is flexible yet robust enough to accommodate both the derogatory and appropriative use of slurs, can explain many of the psychological effects that slurs actually have on both their users and targets, and is more in accord with the real rather than ideal nature of our organic human psychology. (shrink)

This essay delineates and analyzes two kinds of questions that sport ethicists tend to ask: questions about athletic excellence and questions about justice. To pass ethical judgements when delving into questions concerning athletic excellence, sportspeople rely largely on a sport’s internal values, primary skills, or sport-specific athletic excellences. In contrast, questions about justice do not and should not include the reference or application of principles derived from the nature of a sport. Instead, sportspeople must refer to general theories, most often (...) based on the rights and obligations of fellow citizens. There are multiple benefits to pointing out this distinction. First, it can help sportspeople and sport philosophers recognize the normative standards most appropriate within specific debates. Second, the distinction may explain why some disputes in sport philosophy remained unresolved. Finally, and perhaps most significantly, an awareness of the differences between these types... (shrink)

There are at least two basic normative notions: rationality and reasons. The dominant normative account of reasons nowadays, which I call primitive pluralism about reasons, holds that some reasons are normatively basic and there is no underlying normative explanation of them in terms of other normative notions. Kantian constructivism about reasons, understood as a normative rather than a metaethical view, holds that rationality is the primitive normative notion that picks out which non-normative facts are reasons for what and explains why (...) those normative relations hold. By supposing that there is a plurality of primitive reasons, I argue that primitive pluralism about reasons lacks sufficient normative unity and structure. But Kantian constructivism about reasons faces a dilemma of its own: Either a conception of rationality is thick enough to capture the reasons of commonsense, in which case it cannot play the explanatory role assigned to it, or a conception of rationality is genuinely explanatory, in which case it is too thin to generate the reasons we recognize in commonsense. The aim of this paper is to suggest that if Kantian constructivism about reasons were built on a substantive, rather than merely formal, conception of rationality then it would stand a better chance at unifying the particular reasons we would endorse on due reflection. The groundwork I lay in this paper, I explain, is an essential first step in the larger project of developing a version of Kantian constructivism about reasons that might eventually explain all reasons in terms of rationality. (shrink)

In this paper, we use the biology of pain and Augustinian insights into the relationship between physical and spiritual death to give a defense of the Fall. If we think of pain as, biologically, a limiting system but one that interacts with advanced rationality in such a way as to create a new experience of one’s biological limits, then one can use Augustine’s treatment of our experience of physical death as both a consequence and a symbolic check on our moral (...) and spiritual condition to give an account of the Fall that is consistent with evolutionary theory. (shrink)

Science and technology have been integral issues of development cooperation for more than sixty years. Contrary to early efforts’ transfer of established technologies from the West to developing countries, contemporary technology aspirations increasingly articulate and practice the Global South as a live laboratory for technological experimentation. This approach is especially furthered by a group of private foundations and philanthrocapitalists whose endeavors in developing countries are, like their companies, shaped by logics of the individual, the market, and of societal progress through (...) technological innovation and experimentation. This article draws upon critical intellectual thought about the political and social ramifications of technology to reflect on the renascent role of technology in development cooperation. It traces the discourses and practices of philanthrocapitalist organizations, in particular the Bill and Melinda Gates Foundation, to understand how their experimentalist technology aspirations influence human life and relations in the Global South. This article argues that this newfound focus on technology in development cooperation may challenge the essence of democracy, reduce participation, and have undesirable consequences for populations in the Global South. (shrink)

Since their discovery, mirror neurons have played a critical role in the interdisciplinary debate over how we come to understand other people, a topic often labelled 'mind-reading'. The philosopher Alvin Goldman argues that mirror neurons provide critical evidence that we come to understand others by simulating them. In this paper, I demonstrate that mirror neurons should be thought of as facilitating the perception of persons but should not be thought of as simulators. Our basic understanding of others does not come (...) from thinking our way into their shoes but rather through seeing into their minds through their pattern behaviour. (shrink)

I discuss two forms of the thesis that to have a sensation is to token a sentence in a language of thought-what I call, following Georges Rey, the sensational sentences thesis. One form of the thesis is a version of standard functionalism, while the other is a version of the increasingly popular thesis that for a sensation to have qualia is for it to have a certain kind of intentional content-that is, intentionalism. I defend the basic idea behind the sensational (...) sentences thesis, and argue that the intentionalist version is either false or collapses into the standard functionalist thesis. (shrink)

Brette contends that the neural coding metaphor is an invalid basis for theories of what the brain does. Here, we argue that it is an insufficient guide for building an artificial intelligence that learns to accomplish short- and long-term goals in a complex, changing environment.