Finding that an avian herpesvirus can cause atherosclerosis in chickens prompted studies of human herpesviruses in human atherosclerosis. Antigens and nucleic acid sequences of cytomegalovirus (CMV), a widespread member of the herpesvirus family, were found in arterial lesions in human atherosclerosis, but infectious virus has not been observed. In atherosclerosis patients, high levels of CMV antibodies are present, suggesting the presence of virus that had been activated from a latent state. Atherosclerosis also develops in immunesuppressed heart transplant patients infected with (...) CMV. The properties of CMV are consistent with its involvement at several levels of the atherogenic process. If this concept is correct, immunization with a CMV vaccine should prevent CMV infection and atherosclerosis. (shrink)

The author offers a comprehensive interpretation of Aquinas's claim that the human intellect is immaterial and assessment of his arguments on behalf of this claim, also positioning Aquinas's thought alongside recent work in hylomorphic metaphysics and philosophy of mind.

In multi-agent systems (MAS), abstract argumentation and argumentation schemes are increasingly important. To be useful for MAS, argumentation schemes require a computational approach so that agents can use the components of a scheme to construct and present arguments and counterarguments. This paper proposes a syntactic analysis that integrates argumentation schemes with abstract argumentation. Schemes can be analysed into the roles that propositions play in each scheme and the structure of the associated propositions, yielding a greater understanding of the schemes, a (...) uniform method of analysis, and a systematic means to relate one scheme to another. This analysis of the schemes helps to clarify what is needed to provide denotations of the terms and predicates in a semantic model. (shrink)

Most contemporary interpreters of Aquinas have assumed that Thomas subscribed to a “non-repeatability principle” such that created entities, once destroyed entirely, cannot be “brought back" into existence, even by God's power. Souls persisting in the interim between death and resurrection thus play an essential identity-preserving role between our death and rising again. No separated souls, no resurrection. Two of Aquinas’s best medieval interpreters, however, reject this interpretation. Leaning largely on one of Aquinas’s late quodlibetal questions, they deny that Thomas held (...) any non-repeatability principle strong enough to bar God’s resurrecting us even from complete destruction, souls and all. Here the chapter argues that careful analysis of the quodlibet and other texts largely vindicates the contemporary interpretation. It does so in a surprising way, however, since it turns out Aquinas’s non-repeatability principle applies only to corruptible, material entities like us, and not to incorruptible entities like angels. The reason Aquinas held this view, the chapter argues, is rooted in his theory of individuation. (shrink)

James Adam was a Scottish classics scholar who taught at Emmanuel College, Cambridge. A strong defender of the importance of Greek philosophy in a well-rounded education, Adam published a number of Plato's works including Protagoras and Crito. This two-volume critical edition of the Republic was another major contribution to the field. Though his preface claims 'an editor cannot pretend to have exhausted its significance by means of a commentary,' Adam's depth of knowledge and erudite analysis of the (...) Greek text ensured that his edition remained the standard reference for decades to follow, and it remains a thought-provoking evaluation of one of the great works of Western thought. Volume 1 is devoted to Books 1–5, which discuss justice and the ideal society, while Volume 2 presents Books 6–10, on the place of the philosopher and questions of governance. (shrink)

This paper provides a sustained investigation into ancient teichopolitics – the politics of constructing walls – and the question of whether the best city should be surrounded by walls. Plato’s Laws adopts the Spartan view that walls have a negative effect on national character and argues that they should be ‘left lying asleep and undisturbed in the ground’. Aristotle’s Politics puts forward a series of objections to Plato and adopts the more pragmatic view that walls are necessary. Although both philosophers (...) debate the status of walls and foreigners within the best city, they fail to draw the thoroughly modern connection between teichopolitics and immigration. (shrink)

At the origins of bioethics, Daniel Callahan argued that if these newfangled bioethicists were going to be useful to physicians and policymakers, they would need to offer something like a recipe fo...

: Critics of Nozick have claimed that his formulation of the Lockean proviso is too permissive to serve as a morally plausible constraint on resource acquisition. In this essay, I advance a new critique of Nozick’s entitlement theory. In particular, I argue that even on his own permissive formulation of the Lockean proviso, he faces ….

Some philosophers claim that there is no morally relevant distinction to be made between duties of rescue and beneficence. In this paper I will highlight an undesirable implication of this position: over-demandingness. After rejecting a prominent attempt to address this problem, I will then advance a virtue-ethical principle that adequately distinguishes the relevant duties and avoids over-demandingness. This principle links wrong actions to character by focusing on the vice of contempt for humanity. Here I will engage with Michael Slote’s similar (...) efforts, critiquing and improving upon them. This essay addresses a gap in the literature on positive duties by appealing to relevant virtue-ethical considerations from within a Neo-Aristotelian framework. (shrink)

Prevailing philosophies about parental and other caregiver responsibilities toward children tend to be protectionist, grounded in informed benevolence in a way that countenances rather than circumvents intrusive paternalism. And among the kinds of children an adult might be called upon to parent or otherwise care for, children with disabilities figure among those for whom the strongest and snuggest shielding is supposed be deployed. In this article, we examine whether this equation of securing well-being with sheltering by protective parents and other (...) care-givers should unreflectively be adopted for disabled children. We also consider why healthcare providers might reasonably be reluctant to yield to this principle, even if parents instinctively suppose that protectionism is the parenting policy that best serves their disabled child’s interest. We contend that caregivers owe children with disabilities at least as much, and possibly more, respect for self-governance than other children need. In spite of disabled children’s vulnerability and even in view of it, we argue that they should be accorded not only welfare rights to well-being but at least a modified version of liberty rights as well. Healthcare providers are especially favorably positioned to facilitate the latter response. The main components of respectful caregiving can come into conflict with one another, but we present some priorities that advise against adopting a protectionist account of parenting rights, or at least against accepting protectionist views that focus parenting narrowly on shaping ideas about the child’s welfare. In sum, caring for a disabled child, we argue, involves more than creating conditions that will afford her contentment and comfort over the course of life. (shrink)

This article explores the critical history and reception of Charles Churchill, the mid-eighteenth century satirist, looking in particular at his skepticism towards all authority as a questioning of traditional ideas of `enlightenment', and at the reasons for the meteoric but short-lived nature of his poetic success.

It is commonly believed that the moral norms of “everyday” or “traditional” morality apply uniformly in all business contexts. However, Joseph Heath has recently argued that this is not the case. According to Heath, the norms of everyday morality apply with respect to “administered” transactions, but not “market” transactions. Market transactions are, he argues, governed by a distinct, “adversarial” morality. In this essay, I argue that Heath’s attempt to show that competitive contexts are governed by a distinct, adversarial morality does (...) not succeed. I then undertake the task of showing that, contrary to what is commonly thought, competitive actions can be reconciled with the norms of traditional morality. (shrink)

[t. 1.] 1750-1830 -- [t. 2.] 1831-1864 -- [t. 3.] 1865-1895 -- [t. 4., zesz. 1.-2.] 1896-1918.

In The Passion for Happiness, I attempt to situate Johnson alongside Hume within a common Enlightenment culture and, in so doing, to give us a better idea of what that culture is, or may be said to be. I am concerned in the book to analyze what I see as their shared debts to classical eudaimonism, particularly as it is presented in the philosophical dialogues of Cicero. In this regard, my book builds upon Peter Jones’s Hume’s Sentiments: Their Ciceronian and (...) French Contexts ; I am also deeply indebted to some recent re-interpreters of Hellenistic ethics, especially to Martha Nussbaum, Julia Annas, and Lawrence Becker. A third of my book, however, is devoted to a discussion of Johnson and Hume’s roughly parallel—and, I think, mutually illuminating—careers as political writers and commentators, including the political and moral casts of their historiographical writings. The titles of chapters 7 through 9—“The Passions and Patterns of History,” “Enthusiasm and Empire,” “Constancy”—suggest at least my hopes that The Passion for Happiness might be of some interest to intellectual and political historians. (shrink)

This paper attempts to listen to Scott Walker and Sunn O)))’s respective music, and their collaboration Soused, by way of Maurice Blanchot’s notion of disaster which is framed in relation to the ‘a...