Adaptive phenotypic plasticity allows organisms to cope with environmental variability, and yet, despite its adaptive significance, phenotypic plasticity is neither ubiquitous nor infinite. In this review, we merge developmental and population genetic perspectives to explore costs and limits on the evolution of plasticity. Specifically, we focus on the role of modularity in developmental genetic networks as a mechanism underlying phenotypic plasticity, and apply to it lessons learned from population genetic theory on the interplay between relaxed selection and mutation accumulation. We (...) argue that the environmental specificity of gene expression and the associated reduction in pleiotropic constraints drive a fundamental tradeoff between the range of plasticity that can be accommodated and mutation accumulation in alternative developmental networks. This tradeoff has broad implications for understanding the origin and maintenance of plasticity and may contribute to a better understanding of the role of plasticity in the origin, diversification, and loss of phenotypic diversity. (shrink)

This book draws its inspiration from Hilbert, Wittgenstein, Cavaillès and Lakatos and is designed to reconfigure contemporary philosophy of mathematics by making the growth of knowledge rather than its foundations central to the study of mathematical rationality, and by analyzing the notion of growth in historical as well as logical terms. Not a mere compendium of opinions, it is organised in dialogical forms, with each philosophical thesis answered by one or more historical case studies designed to support, complicate or question (...) it. The first part of the book examines the role of scientific theory and empirical fact in the growth of mathematical knowledge. The second examines the role of abstraction, analysis and axiomatization. The third raises the question of whether the growth of mathematical knowledge constitutes progress, and how progress may be understood. Readership: Students and scholars concerned with the history and philosophy of mathematics and the formal sciences. (shrink)

Aristotle claims that in making an animal, nature acts like a “good housekeeper” who “is accustomed to throw out nothing from which it is possible to make something useful” (744b16–17). How does nature act when it “make[s] something useful” in these cases – and does it differ from other ways it acts? I defend two main claims. The first is that Meteor. 4.2’s distinction between two sorts of ‘concoction’ processes offers an underappreciated source of evidence for answering this question. My (...) second claim concerns the nature of those processes and the ends they realize. While they are both the ends of their respective types of concoction, they differ in that some essential (process-defining) features of the second end – but not the first – are supplied by what the capacities of the “underlying” patient (on which the agent acts) are for. The result is a distinction between two kinds of end-directed efficient causation. (shrink)

Research on the specific features of daydreaming compared with mind-wandering and night dreaming is a neglected topic in the philosophy of mind and the cognitive neuroscience of spontaneous thought. The extant research either conflates daydreaming with mind-wandering (whether understood as task-unrelated thought, unguided attention, or disunified thought), characterizes daydreaming as opposed to mind-wandering (Dorsch, 2015), or takes daydreaming to encompass any and all “imagined events” (Newby-Clark & Thavendran, 2018). These dueling definitions obstruct future research on spontaneous thought, and are insufficiently (...) precise to guide empirical studies. They also fail to illuminate the phenomenal core of daydreaming, namely, its dreamlike qualities. Although daydreaming is related to both mind-wandering and narrative imagination, it is not reducible to either. We argue that daydreams are experiences of spontaneous, immersive imagination in the waking state. The main task of our investigation is to distinguish daydreaming, conceptually and phenomenologically, from mind-wandering, on the one hand, and night dreaming, on the other. Although daydream experiences can vary widely, we distinguish prototypical experiences of daydreaming from adjacent imaginative activity, including fleeting imagery and “focused daydreaming,” or crafted visualization. We consider our phenomenological analysis as preparatory work for conceptually distinguishing different spontaneous and imaginative states so that they can be investigated accordingly with questionnaires and qualitative methods. We argue that precision about the phenomenal character of daydreaming can guide neurophenomenological investigations, help delimit studies on individual variance in daydreaming features, and identify differences among daydreaming, mind-wandering, and night dreaming conceptually and phenomenologically, and possibly eventually in terms of neural correlates. (shrink)

Beziehungen sind nicht gegeben, sie werden gemeinsam gemacht. Der Band untersucht Relationalitäten als prozessuale Aushandlungen zwischen Künsten und Wissenschaften, zwischen gebautem Raum und sozialem Körper, zwischen theoretischem und poetisch-künstlerischem Schreiben und Sprechen, zwischen Form, Material und Handlung. Plädiert wird für eine Wissenspolitik der Künste, die von einer radikalen Verstricktheit theoretischer, ästhetischer, medialer und gesellschaftlicher Praktiken und Techniken ausgeht. Mit Beiträgen von / with contributions by Bini Adamczak, Emily Apter, Alice Chauchat, Beatriz Colomina, Gradinger / Schubot, Annika Haas, Maximilian Haas, (...) Orit Halpern, Tom Holert, Amy Lien & Enzo Camacho, Maurício Liesen, Hanna Magauer, Michaela Ott, Sibylle Peters, Dennis Pohl, Possible Bodies (Helen Pritchard, Jara Rocha, Femke Snelting), Ghassan Salhab, Mirjam Schaub, Melanie Sehgal, Nora Sternfeld, Kathrin Thiele, Jeremy Wade, Brigitte Weingart. (shrink)

Research that is integrated into ongoing clinical activities holds the potential to accelerate the generation of knowledge to improve the health of individuals and populations. Yet integrating research into clinical care presents difficult ethical and regulatory challenges, including how or whether to obtain informed consent. Multiple empirical studies have explored patients' and the public's attitudes toward approaches to consent for pragmatic research. Questions remain, however, about how to use the resulting empirical data in resolving normative and policy debates and what (...) kind of data warrants the most consideration. We recommend prioritizing data about what people consider acceptable with respect to consent for pragmatic research and data about people's informed, rather than initial, preferences on this subject. In addition, we advise caution regarding the weight given to majority viewpoints and identify circumstances when empirical data can be overridden. We argue that empirical data bolster normative arguments that alterations of consent should be the default in pragmatic research; waivers are appropriate only when the pragmatic research would otherwise be impracticable and has sufficiently high social value. (shrink)

Mills argues for a new critical theory that develops the insights of the black radical political tradition. While challenging conventional interpretations of key Marxist concepts and claims, the author contends that Marxism has been 'white' insofar as it has failed to recognize the centrality of race and white supremacy to the making of the modern world.

Explainable AI (xAI) methods are important for establishing trust in using black-box models. However, recent criticism has mounted against current xAI methods that they disagree, are necessarily false, and can be manipulated, which has started to undermine the deployment of black-box models. Rudin (2019) goes so far as to say that we should stop using black-box models altogether in high-stakes cases because xAI explanations ‘must be wrong’. However, strict fidelity to the truth is historically not a desideratum in science. Idealizations (...) – the intentional distortions introduced to scientific theories and models – are commonplace in the natural sciences and are seen as a successful scientific tool. Thus, it is not falsehood qua falsehood that is the issue. In this paper, I outline the need for xAI research to engage in idealization evaluation. Drawing on the use of idealizations in the natural sciences and philosophy of science, I introduce a novel framework for evaluating whether xAI methods engage in successful idealizations or deceptive explanations (SIDEs). SIDEs evaluates whether the limitations of xAI methods, and the distortions that they introduce, can be part of a successful idealization or are indeed deceptive distortions as critics suggest. I discuss the role that existing research can play in idealization evaluation and where innovation is necessary. Through a qualitative analysis we find that leading feature importance methods and counterfactual explanations are subject to idealization failure and suggest remedies for ameliorating idealization failure. (shrink)

The last decade has witnessed renewed attempts to regulate the conduct of transnational corporations. One way to do this is via global ethics codes. This paper examines seven such codes (the Sullivan Principles, UN Center for Transnational Corporations’ Draft Code, OECD Guidelines, ILO's Tripartite Declaration, the Caux Round Table Principles for Business, Global Compact, and the United Nations Norms) to determine their coverage of human rights and concludes that if these initiatives succeed, particularly the more recent codes, transnational corporations may (...) emerge as a major force in promoting human rights globally. (shrink)

This short comment on the Court of Protection decision in W v M draws attention to the primacy the judge gave to the preservation of life and discusses the relative lack of weight accorded to M's previously expressed views.

The sublime has been a relatively neglected topic in recent work in philosophical aesthetics, with existing discussions confined mainly to problems in Kant's theory.1 Given the revival of interest in his aesthetic theory and the influence of the Kantian sublime compared to other eighteenth-century accounts, this focus is not surprising. Kant's emphasis on nature also sets his theory apart from other eighteenth-century theories that, although making nature central, also give explicit attention to moral character and mathematical ideas and generally devote (...) more discussion to art and artifacts than Kant did.2 Recent postmodern and poststructuralist theories of the sublime tend to concentrate on the concept in art and .. (shrink)

This book provides a systematic, philosophical account of the main issues that pertain to the aesthetics of modified environments, as well as new insights concerning the generation and appreciation of landscapes and environments that fall between nature and culture, including gardens and ecologically restored landscapes.

Just as the nation is imagined and produced through everyday rhetoric and maps and flags, it is also constructed on the skin, and through bodies, by different types of corporeal `flagging'. In this article, I use two examples of contemporary surgical procedures to explore these dynamics. Aesthetic surgeries on `white' subjects are not often interrogated for their racializing effects, but I use the concept of `flagging' to explore how these surgeries work in the UK to align `white' bodies with a (...) white nation. US media coverage of Iraq invasion veterans with prosthetic limbs circulates narratives of heroism and patriotism, and I explore how the apparent `visibility' of these limbs works to re-embed notions of the US as a transcendent Christian nation. In these two examples of corporeal modification, the nation is `flagged' on the skin, reiterating relationships of belonging that echo practical and conceptual links with property. Propertied belonging — possessive and constitutive — unfolds through bodies, producing whiteness not only as property itself, but also as unmarked, habitual terrain. (shrink)

In her recent book, Realism in mathematics, Penelope Maddy attempts to reconcile a naturalistic epistemology with realism about set theory. The key to this reconciliation is an analogy between mathematics and the physical sciences based on the claim that we perceive the objects of set theory. In this paper I try to show that neither this claim nor the analogy can be sustained. But even if the claim that we perceive some sets is granted, I argue that Maddy's account fails (...) to explain the key issue faced by an epistemology for mathematics, namely the step from knowledge of the finite to knowledge of the infinite. (shrink)

The concept of self-gaslighting has recently become prevalent in popular discourse but has yet to be subjected to detailed philosophical analysis. In this paper, I examine one context in which self-gaslighting is often discussed: situations in which someone has experienced trauma. I argue that the phenomenon currently described as self-gaslighting fails to display core features of manipulative gaslighting and that therefore we should seek other conceptual resources for understanding such cases. I suggest that self-gaslighting, at least in some paradigmatic cases, (...) amounts to either extremely successful interpersonal gaslighting or to internalized oppression. Utilizing these concepts instead of self-gaslighting avoids conceptual difficulties and also has a significant practical payoff. By moving away from the language of self-gaslighting we can move away from feelings of self-blame that so often accompany trauma. (shrink)

Despite having paved the way for face, womb and penis transplants, hand transplantation today remains a small hybrid of reconstructive microsurgery and transplant immunology. An exceptionally limited patient population internationally complicates medical researchers’ efforts to parse outcomes “objectively.” Presumed functional and psychosocial benefits of gaining a transplant hand must be weighed in both patient decisions and bioethical discussions against the difficulty of adhering to post-transplant medications, the physical demands of hand transplant recovery on the patient, and the serious long-term health (...) risks of immunosuppressant drugs. This paper relates five narratives of hand transplantation drawn from an oral history project to show how narrative methods can and should inform ethical evaluations and the clinical process of hand transplantation. The interviews with patients and their partners analyzed here lead us to suggest that qualitative accounts of patient experiences should be used to complement clinical case studies reported in medical journals and to help develop instruments to assess outcomes more systematically. (shrink)

This paper explores the significance of Adam Smith's ideas for defending non-cognitivist theories of aesthetic appreciation of nature. Objections to non-cognitivism argue that the exercise of emotion and imagination in aesthetic judgement potentially sentimentalizes and trivializes nature. I argue that although directed at moral judgement, Smith's views also find a place in addressing this problem. First, sympathetic imagination may afford a deeper and more sensitive type of aesthetic engagement. Second, in taking up the position of the impartial spectator, aesthetic judgements (...) may originate in a type of self-regulated response where we stand outside ourselves to check those overly humanizing tendencies which might lead to a failure in appreciating nature as nature. (shrink)

This article explores the idea that there is a spectrum of individuals who feel compelled to dwell in the past, either due to psychological or social conditions. I analyze both conditions respectively by critically examining two cases: post-traumatic stress disorder and racialized oppression. I propose that individuals with PTSD can feel psychologically compelled to dwell in the past in a dually negative sense: the individual lives in the past but also broods on it, causing them to feel “stuck” in the (...) past. This kind of “dwelling” can cause individuals to suffer disruptions to their sense of self and intersubjectivity. After exploring the psychological case of dwelling in the past, I explore the social sense in which individuals can dwell in the past due to oppressive social structures by examining the case of racialized oppression. The case of racialization is philosophically stimulating because of its intersubjective dimensions—it subverts the idea that dwelling in the past is simply a psychological phenomenon by capturing that others can help or hinder us with maintaining a sense of self and future-directed intentionality. By putting the phenomenological work of Al-Saji into conversation with recent phenomenological research on incarceration, I propose that racialization can be similarly disruptive to one’s sense of self and intersubjectivity. The proposed account is suggestive that traumatic and oppressive experiences may amplify and compound each other in ways not yet well elucidated in the literature. If this account is taken to be persuasive, it is indicative that both psychological and social conditions mediate one’s temporality and well-being. (shrink)

(2013). Introduction: Methodology, systemic risk, and the economics profession. Journal of Economic Methodology: Vol. 20, Methodology, Systemic Risk, and the Economics Profession, pp. 1-5. doi: 10.1080/1350178X.2013.774842.

This book present research in ethics with topics including a step-by-step guide to students; wellbeing and disadvantage; ethical disposition of accounting and business management students; collegiality of journals and self-citation on annual bibliometric scorings; trends of tainted publications and their authors' publication profiles; from bioethics to biopolitics and the limits of liberalism.

(1982). ’What is the Good?’: a comparison of young people's responses to two unfinished sentences about values. Educational Studies: Vol. 8, No. 2, pp. 113-121.

Tree-chopping in the Aeneid has long been seen as a disturbingly violent symbol of the Trojans' colonization of Italy. The paper proposes a new reading of the poem which sees Aeneas as progressive extirpator not just of foreign rivals but also of his own Trojan relatives. Although the Romans had no family “trees” as such, their genealogical stemmata (“garlands”) had “branches” (rami) and “stock” (stirps), and their vocabulary of family relationships takes many of its metaphors from planting, adoption, and uprooting, (...) while plant life is often described in human metaphors. Imperial historians use the growth and collapse of trees to mark the rise and fall of dynasties; natural historians like Columella and Pliny use metaphors of adoption, abortion, and adultery to characterize the perversions of agriculture and horticulture. It is thus no coincidence that Aeneas' encounters with Hector, Priam, Deiphobus, and others often take place against a background of real or metaphorical trees (tree similes, headless or mutilated human trunks, ancient trees and woods). These encourage us to see an element of dynastic encroachment in scenes that look pious and peaceable but confirm Aeneas' ascendancy and claim to Trojan succession. The Polydorus episode in particular can be read not just as a grotesque interlude but as a nightmare about endlessly reproducing heirs; one loose strand from Priam's house is allowed to remain, while Virgil deals imperfectly with the problem of Aeneas' own successors. The paper ends by re-examining Virgil's account of grafting in Georgics 2 and arguing that it is viewed positively, perhaps in order to cast Augustus' adoption of heirs as a miracle solution. (shrink)

Opponents of same-sex marriage suggest that legalizing same-sex marriage will start a slide down a “slippery-slope” leading to the legalization of all kinds of salacious family arrangements including polygamy. In this paper, I argue that because previous attempts by liberal political theorists to combat such slippery-slope arguments have been unsuccessful, there are two options left open to political liberals. Either one could embrace polygamy as a logically consistent implication of extending civil liberties to same-sex couples or one could find a (...) new strategy for blocking the slide down the slope. I take the second option arguing that we ought to devise a harm principle for domestic partnerships. Once this principle has been established, it becomes clear that the risk of exploitation for those potentially occupying the multiple side of the marriage is sufficient reason to reject polygamous marriage arrangements. I conclude that, contrary to appearances, holding both same-sex marriage is permissible and polygamous marriage is impermissible is at the same time consistent and consistently liberal. (shrink)

Despite significant advances in neurotechnology, the development of assistive devices often fails to take into account the nuanced needs and preferences of its disabled users into the design proces...

The Spartan Rhetra quoted by Plutarch in Lyc. vi. 2 consists of some thirty-seven words in an archaic Dorian or near-Dorian dialect: Plutarch says it was an oracle, and that later an extra clause was added by the kings Polydoros and Theopompos; he quotes this ‘added clause’ in vi. 8. I believe this Rhetra was not an oracle but an act of the Spartan Ekklesia; and I suspect that the ‘added clause’ was not added, but is an integral part of (...) the original act. But for our first objective this opinion matters less than Plutarch's opinion. Our first objective must be to recover Plutarch's text : and to do that, we must understand his interpretation. (shrink)

abstract: In 1880s Britain, Constance Naden defended “hylo-idealism,” a theory aiming to unify materialism with idealism. This paper offers the first sustained study of Naden’s metaphysical system. On this new reading of Naden’s hylo-idealism, her materialism is carefully qualified; and her idealism is distinctively Kantian, her construal of the external cosmos as Unknown placing her within the Victorian school of metaphysical agnostics. I distinguish Naden’s system from that of fellow hylo-idealist Robert Lewins and argue it lies closer to that of (...) evolutionist Thomas Henry Huxley. Against various critics, I show that Naden has the resources to rebuff objections facing hylo-idealism. This paper seeks to open further avenues for Naden scholarship and help us better understand Victorian metaphysics more generally. (shrink)

Increased awareness of neurodiverse conditions has necessitated reexamination of neurodiversity in relation to societal norms and material conditions. ‘Neuro-neutrality’, as proposed by de Vries (2...

Before we take up the arguments directly, there is one general point about Socrates' position that he considered essential to everything he said in the Crito. Also, he thought that this point was easily missed. He calls it his "starting point." It is that "we ought neither to requite wrong with wrong nor to do evil to anyone, no matter what he may have done to us." And Socrates warns Crito not to accept this position too quickly or without full (...) consideration, "for I know that there are few who believe or ever will believe this". Yet this moral principle is so essential to his arguments that "those who believe this, and those who do not, have no common ground of discussion, but they must necessarily, in view of their opinions, despise one another". This position, never to harm others in any circumstance, is "the starting point of our discussion...". (shrink)