A precise formulation of the structure of modern evolutionary theory has proved elusive. In this paper, I introduce and develop a formal approach to the structure of population genetics, evolutionary theory's most developed sub-theory. Under the semantic approach, used as a framework in this paper, presenting a theory consists in presenting a related family of models. I offer general guidelines and examples for the classification of population genetics models; the defining features of the models are taken to be their state (...) spaces, parameters, and laws. The suggestions regarding the various aspects of the characterization of population genetics models provide an outline for further detailed research. (shrink)

Philosophers have often adopted a dismissive attitude toward metaphor. Hobbes (1651, ch. 8) advocated excluding metaphors from rational discourse because they “openly profess deceit,” while Locke (1690, Bk. 3, ch. 10) claimed that figurative uses of language serve only “to insinuate wrong ideas, move the passions, and thereby mislead the judgment; and so indeed are perfect cheats.” Later, logical positivists like Ayer and Carnap assumed that because metaphors like..

Socially responsible investment (SRI) has become a major intervention in global investment practices that responds to the power of institutional investors to affect corporate practice. While SRI grew out of the decisions made by churches to curtail investment in so-called “sin stocks” (companies which profited from alcohol, tobacco and gambling), little work has been done to explain why such a dramatic difference in investment strategy would occur or how it ought to impact the investment decisions of individual Christians and their (...) faith communities. This paper explores how social institutions with a religious character determine how to balance the risk of inflicting harm on those institutions with responsibility for transforming the economic order through making investment decisions. Using data collected from shareholder proposals in corporate proxy filings and interviews with investment managers, we develop a typology of theologically grounded approaches to risk and responsibility. (shrink)

Three basic assumptions distinguish Thucvdides' historical perspective from the perspective of the debate speeches in his history: he did not assume that events are continuous or repeatable, that human nature in unchangeable, and that the ultimate causes of human affairs are within human ken. In Thucydides' history, statesmen and citizens are judged by their capacities to do as Thucydides himself tried to do -judge novelty and greatness clearly. Lastingly effective good judgment unifies people because it stems from and appeals to (...) respect for the imponderables of human affairs, the unpredictability of the future and the fragility of human nature. Those who can appreciate novelties know that the future will not be lacking in them, as those who can appreciate greatness know that its causes are ultimately beyond analysis. Like Thucydides himself, such people are storytellers rather than moralists. (shrink)

This article presents a study of how co-present individuals work out the nature of embodied engagement and disengagement displays by individuals with dementia in a Danish public care facility. Research has found that moderate to severe dementia may result, for example, in a lack of social engagement, apathy and problems in maintaining conversations. Research has, however, also found that co-present individuals indicate their right to unavailability for social interaction. This is accomplished through details of embodied and multimodal conduct such as (...) gaze behavior, which includes practices of glancing and gazing at co-present individuals or practices of gazing into space. These practices may coincide with indications of ‘lack of social engagement’ and ‘apathy’. This study falls within the framework of ethnomethodology and employs multimodal conversation analytic methods to show how co-present individuals monitor residents’ displays of engagement and disengagement, primarily gaze behavior and how they respond to them. The study is based on 20 hours of video-recordings. (shrink)

We consider the question of when, given a subset A of M, the setwise stabilizer of the group of automorphisms induces a closed subgroup on Sym(A). We define s-homogeneity to be the analogue of homogeneity relative to strong embeddings and show that any subset of a countable, s-homogeneous, ω-stable structure induces a closed subgroup and contrast this with a number of negative results. We also show that for ω-stable structures s-homogeneity is preserved under naming countably many constants, but under slightly (...) weaker conditions it can be lost by naming a single point. (shrink)

BackgroundThe Liverpool Care Pathway is an interdisciplinary protocol, aiming to ensure that dying patients receive dignified and individualized treatment and care at the end-of-life. LCP was originally developed in 1997 in the United Kingdom from a model of cancer care successfully established in hospices. It has since been introduced in many countries, including Norway. The method was withdrawn in the UK in 2013. This review investigates whether LCP has been adapted and validated for use in nursing homes and for dying (...) people with dementia.MethodsThis systematic review is based on a systematic literature search of MEDLINE, CINAHL, EMBASE, and Web of Science.ResultsThe search identified 12 studies, but none describing an evidence-based adaption of LCP to nursing home patients and people with dementia. No studies described the LCP implementation procedure, including strategies for discontinuation of medications, procedures for nutrition and hydration, or the testing of such procedures in nursing homes. No effect studies addressing the assessment and treatment of pain and symptoms that include dying nursing home patients and people with dementia are available.ConclusionLCP has not been adapted to nursing home patients and people with dementia. Current evidence, i.e. studies investigating the validity and reliability in clinically relevant settings, is too limited for the LCP procedure to be recommended for the population at hand. There is a need to develop good practice in palliative medicine, Advance Care Planning, and disease-specific recommendations for people with dementia. (shrink)

Holophobia can be defined as the 'neurotic' fear that semantic holism, if not instantly extirpated by the most radical means, might be a deadly threat to intentional realism. I contend that Fodor exaggerates the threat that meaning holism poses to intentional realism and to a viable account of narrow content in terms of conceptual roles. He particular, he overestimates the relevance for intentional psychology of Quine's demonstration that a substantial analytic/synthetic distinction is out of reach.I argue that all that is (...) needed to defeat the more radical varieties of meaning holism is a weaker distinction than the full-blown and allegedly inexistent analytic/synthetic distinction - namely, a distinction between what is treated as if it were analytic by a cognitive system and what is treated as if it were synthetic. (shrink)

Lorazepam has been repeatedly shown to induce memory impairments. The effects of this benzodiazepine on the processes involved in the strategic regulation of memory accuracy have not as yet been explored. An experimental procedure that delineates the role of monitoring and control processes was used. Fifteen lorazepam and 15 placebo subjects were examined using a semantic memory task that combined both a forced- and a free-report option and a no-incentive and an incentive condition. Memory accuracy was lower in the lorazepam (...) than in the placebo group. Lorazepam impaired control sensitivity . While the absolute aspect of monitoring was impaired , both the discriminative aspect and the response criterion setting were spared. The pharmacological dissociation between monitoring effectiveness and control sensitivity indicates that these two components involve distinct processes. (shrink)

Backgrounds Most countries are facing increased pressure on healthcare resources. A better understanding of how healthcare providers respond to new demands is relevant for future pandemics and other crises. Objectives This study aimed to explore what nurses and doctors in Norway reported as their main ethical challenges during two periods of the COVID-19 pandemic: February 2021 and February 2022. Research design A longitudinal repeated cross-sectional study was conducted in the Western health region of Norway. The survey included an open-ended question (...) about ethical challenges among doctors and nurses in hospital departments. Free-text comments were analysed using Systematic Text Condensation and also presented in a frequency table. Ethical considerations Ethical approval was granted by the Regional Research Ethics Committee in Western Norway (131,421). All participants provided consent when participating in the study. Results In 2021, 249 and in 2022, 163 healthcare professionals responded to the open-ended question. Nurses and doctors reported three main categories of ethical challenges related to the COVID-19 pandemic: (1) barriers that hindered them in acting as they ethically would have wanted to do; (2) priority-setting dilemmas linked to overtreatment, transfer of resources and ranking patient needs; and (3) workload expansion threatening work–life balance and employees’ health. Category one comprised of resource barriers, regulatory barriers, system barriers, and personal barriers. Regulatory barriers, especially visitor restrictions for next-of-kin, were the most frequently reported in 2021. Resource barriers, related to the increased scarcity of qualified staff, were most frequently reported in 2022. Clinicians stretched themselves thin to avoid compromising on care, diagnostics, or treatment. Conclusions Developing clinicians’ ability to handle and cope with limited healthcare resources is necessary. To foster resilience and sustainability, healthcare leaders, in collaboration with their staff, should ensure fair priority-setting and initiate reflections among doctors and nurses on what it implies to provide ‘good enough’ care. (shrink)

Drawing on existing theory in the fields of business ethics, entrepreneurship, and psychology, this research provides an initial empirical exploration of whether entrepreneurs use cognitive reasoning processes which reflect a higher level of moral development than the level of moral development that has been empirically observed either in middle-level managers or in the general adult population. The Defining Issues Test was used to measure the level of moral reasoning skill of the entrepreneurs in this study. Although the study was limited (...) by a small sample size and the inherent difficulty of making accurate comparisons across other empirical studies, the results of this study suggest that entrepreneurs may exhibit moral reasoning skills at a slightly higher level than middle-level managers or the general adult population. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:Feminist Studies 45, no. 1. © 2019 by Elisabeth Blair 173 How it feels is a series of questions Are you home now, or in the body of a bird? Do you drown, or do you sit calm in the watery air? And the fire—did you light it yourself, or did someone you know, or someone you have yet to meet? Can you sit quiet by it or (...) is it bridging the wet and dry with its feet, consuming your shoes first, then your eyes, skipping the topography in between in fickle pecking like chicken for grain? Is the shower water or is it fire? What if you want to feel something? Are you tired of time, to be so locked into now in this way, in the shower, and later in the circle, where they’ll say, We saw your scars, we know you were abused— it’s OK—we were too— —? But you had only scratched your back in the shower (accidentally) that day. Elisabeth Blair 174 Elisabeth Blair What is the fire that is the fire of drowning and what is the urgency that is the command of fog, saying you’d better sit down? You’d better stand up. Wood. Upholstery. Snow. Mud. These are real, while you are sinister, not believed. There were welts on your back; now they’ve gone. You try to explain: You had a belly once. You had a body. This place stores you in the leg of a bird, and not an invested one but a chicken, pecking, running lines in the ground. Most of the time is gone. You’re a stream down which a foundling comes. You’re a paramecium—all the hints and holds of life are here in you, but you are just a little one. You’re a mouth. You use yourself to laugh, to clutch your chin with one hand, rest the other on your knee. You use yourself to say no, I do not have scars—to clarify. You use yourself like the chicken in the yard uses itself to get by. Elisabeth Blair 175 Listen. I haven’t hit you. I’ve only used your body to demonstrate the richness of your feeling and the piracy inherent in your unwillingness to brave the feeling. I’ve only pulled you up. I’ve only sheltered you with a slap. I’ve dipped into your orange blood with my finger and felt relief—I know how to help. You listen to me— your blood will redden, then your face. You’ll get better. 176 Elisabeth Blair The English boy dwells in any of many neurodivergent states, no doubt undiagnosed. You only speak when spoken to by the staff, but he will and does speak—and laugh. He pulls his pants down and shits in the mess tent. You look at the grain in the rough wooden bench. He kicks as they tackle him to the ground, and all the while—as they swear and shout and he fights—comes that laughter, making ripples on your eyes. They put him in a sleeping bag, wrap a tarp around it, tie it with rope, then leave him on the ground for days, on display, in March, in the mountains, in many feet of snow. They call it a burrito. Let him laugh, they say, let him wiggle and roll.  [we were not killed]  [I am not ungrateful  I am not ungrateful] Elisabeth Blair 177 Age 16 A few years before, your horns newly removed, there had come a drought. Once you felt it, and felt yourself not just alone but marked— once on the forehead and once on either side where you had been but now were not— you developed doubts. You had intended to be reasonable, to talk. But the melting ice: there was no container. The evaporating water: there was no shade. No room to meet in. No family to group. No wits to gather or weave, nothing to save. Your hands became a precipice attached to a belief. The belief was mismanaged, had a bad day. Stuff clattered onto you. You lay there in the stuff and knew you had broken hearts. People... (shrink)

A crítica da cultura como reflexo do mundo que realmente existe é o ponto de partida para a apreensão do caráter social dos sentidos estéticos, manifestamente sobre a criação artística, o conhecimento estético e a produção material sob o capitalismo. Partindo de tal pressuposto, o presente artigo se debruçará sobre a problemática geral da estética e do seu papel formador na cultura.

Easeful Death sets out straightforwardly the arguments for and against the legalization of assisted suicide and euthanasia. Exploring the philosophical and legal debates as well as the medical practicalities of this sensitive issue, the authors ultimately conclude that the law should embrace a more compassionate approach to assisted dying.