Summary The publication in 1906 of Alexander Smith's Introduction to general inorganic chemistry inaugurated a decisive change in chemical pedagogy in the US, the effects of which are still evident. The nature and extent of Smith's innovations are described through a comparison of his text to its source material and contemporaries. His authoritative command of and whole-hearted commitment to the intellectual framework of Ionist physical chemistry set his text apart from its American competitors, while his efforts to make the tools (...) of physical chemistry immediately useful to his readers distinguished it from its most immediate source material, Wilhelm Ostwald's Grundlinien der anorganischen Chemie. Smith's curricular innovations in chemistry were a practical expression of his radically restrictive view of the social role of collegiate education, which he conceived as solely of use for its ability to prepare students for professional life. During the fifteen years prior to the publication of his groundbreaking textbook, Smith underwent two critical, formative experiences. First, he retreated intellectually from the structural organic chemistry in which he was trained, ultimately adopting a professional identity as a physical inorganic chemist. His involvement in the controversy regarding the structure of 1,3-diketones reveals much about his reasons for eventually abandoning organic chemistry. Second, he served the National Education Association as chairman of the Sub-committee on College Entrance Requirements in Chemistry, in the process making a close study of the ends and methods of secondary and collegiate education. These experiences made him unique among proponents of physical chemistry in the US, and help account for the unique nature of his contributions to the development of the chemical professions. (shrink)

The almost 300 articles contain not only historical accounts but also some indication of the state of present day study in classical philosophy.

In lieu of an abstract, here is a brief excerpt of the content:Bibliography of Resources by and about André E. Hellegers*Compiled by Doris Mueller Goldstein (bio)This bibliography is derived from the holdings of the National Reference Center for Bioethics Literature and the BIOETHICSLINE© database (both of which are at the Kennedy Institute of Ethics and supported by the National Library of Medicine); the archives of Lauinger Library, Georgetown University; the Medline databases of the National Library of Medicine; the WorldCat database (...) of OCLC, Dublin, Ohio, and selected Internet sites.Primarily comprised of writings by Dr. Hellegers, the list also includes interviews and media programs in which he participated, as well as writings about him that were written following his death. The arrangement within each section is by date. The 231 authored pieces reflect the transition from Dr. Hellegers’s early career as a researcher in fetal physiology at Johns Hopkins Medical School, where he published his first research report at the age of 29, to the early years of the Kennedy Institute, where he produced so many provocative columns on bioethical issues that influenced the growth of the field.Due to the diversity of sources and the 40-year time span covered, there are some variations in bibliographic style. Time and availability constraints precluded verifying all of the citations with the original documents. Any additions or corrections should be submitted to the compiler.Works Authored by André E. HellegersNo Date Ethical Issues in Sterilization of the Retarded. Unpublished paper.1956Vitamin B12 Serum Level and Pregnancy. American Journal of Clinical Nutrition 4: 440+, 1956. [With Bacon F. Chow and Kunio Okuda] [End Page 89]1957Vitamin B12 Absorption in Pregnancy and in the Newborn. American Journal of Clinical Nutrition 5: 327+, 1957. [With Bacon F. Chow, Robert E. L. Nesbitt, Kunio Okuda, and David W. Smith]1958The Effects of Acute Hypoxia on the Osmotic Pressure of the Plasma. Quarterly Journal of Experimental Physiology 43: 197+, 1958. [With Donald H. Barron, Frederick C. Battaglia, and Giacomo Meschia]Studies on the Absorption of Vitamin B12 in Human Pregnancy with Especial Reference to the Effect of D-Sorbitol. American Journal of Obstetrics and Gynecology 76: 91+, 1958. [With Bacon F. Chow, Harry Prystowsky, and Vernon Wong]1959The Alveolar PCO2 and PO2 in Pregnant and Nonpregnant Women at Altitude. Proceedings of the Society for Clinical Investigation 38: 1010+, 1959. [With Donald Barron, William Huckabee, Giacomo Meschia, James Metcalfe, and Harry Prystowsky]A Comparison of the Oxygen Dissociation Curves of the Bloods of Maternal and Fetal Goats at Various pHs. Quarterly Journal of Experimental Physiology 44: 215–21, July 1959. [With Donald Barron, Giacomo Meschia, Harry Prystowsky, and A. Stark Wolkoff]Fetal Blood Studies. XII. On the Relationship Between the Position of the Oxygen Dissociation Curve of Human Fetal Blood and Adult Fetal Hemoglobin. American Journal of Obstetrics and Gynecology 77: 585+, 1959. [With Paul D. Bruns, Julian Cotter, and Harry Prystowsky]Fetal Blood Studies. XIV. A Comparative Study of the Oxygen Dissociation Curve of Nonpregnant, Pregnant and Fetal Human Blood. American Journal of Obstetrics and Gynecology 78: 489–93, September 1959. [With Paul D. Bruns and Harry Prystowsky]Fetal Blood Studies. XVI. On the Changes in Total Osmotic Pressure and Sodium and Potassium Concentration of Amniotic Fluid During the Course of Human Gestation. Surgery, Gynecology and Obstetrics 109: 509–12, October 1959. [With Frederick Battaglia, Paul D. Bruns, Harry Prystowsky, and Clayton Smisson]Further Observations on the Metabolism of Vitamin B12 in Human Pregnancy. American Journal of Obstetrics and Gynecology 77: 1+, 1959. [With Bacon F. Chow, Harry Prystowsky, Bruno Ranke, and Elma Ranke]The Oxygen Dissociation Curves of the Bloods of Adult and Fetal Llamas. Federation Proceedings 18, 1959. [With Donald Barron, William Huckabee, Giacomo Meschia, James Metcalfe, and Harry Prystowsky] [End Page 90]Transfer of Oxygen Across the Sheep Placenta at High Altitude. Federation Proceedings 18, 1959. [With Donald Barron, William Huckabee, Giacomo Meschia, and Harry Prystowsky]Uterine Blood Flow and Metabolism in Pregnant Sheep at High Altitude. Federation Proceedings 18, 1959. [With Donald Barron, William Huckabee, Giacomo Meschia, James Metcalfe, and Harry Prystowsky]Uterine Blood Flow and Metabolism in Unanesthetized Pregnant Sheep. Federation Proceedings 18, 1959. [With Donald Barron, William Huckabee, Giacomo... (shrink)

University of Chicago Press, 2001 Review by Adriano Palma, Ph.D. on Aug 1st 2001 Volume: 5, Number: 31.

This is the long-awaited third volume of philosophical writings by Davidson, whose influence on philosophy since the 1960s has been deep and broad. His first two collections, published by Oxford in the early 1980s, are recognized as contemporary classics. His ideas have continued to flow; now, in this new work, he presents a selection of his best work on knowledge, mind, and language from the last two decades. It is a rich and rewarding feast for anyone interested in philosophy, and (...) essential reading for anyone working on these topics. (shrink)

The propensity interpretation of probability was introduced by Popper ([1957]), but has subsequently been developed in different ways by quite a number of philosophers of science. This paper does not attempt a complete survey, but discusses a number of different versions of the theory, thereby giving some idea of the varieties of propensity. Propensity theories are classified into (i) long-run and (ii) single-case. The paper argues for a long-run version of the propensity theory, but this is contrasted with two single-case (...) propensity theories, one due to Miller and the later Popper, and the other to Fetzer. The three approaches are compared by examining how they deal with a key problem for the propensity approach, namely the relationship between propensity and causality and Humphreys' paradox. (shrink)

This book argues that the subjective and the objective are crucially dependent on one another and neither is intelligible apart from the other. There is no such thing as a purely external, in-itself world. This book is not intended as a defense of epistemological relativism but as a strong recommendation for modest fallibilism and pluralism.

Research Ethics Boards (REBs) at universities are chaired and staffed by researchers who serve to enforce codes of ethics by scrutinizing research proposals. Yet there is widespread dissatisfaction with the REB approval process. This article examines the sources of that dissatisfaction, the place for codes of ethics in the conducting of research, the evidence for risk to research participants as the basis for those codes, and the effectiveness of REBs in protecting research participants. We offer suggestions for how REB chairs, (...) members, and researchers can improve the REB approval process so that it is fair and responsive. (shrink)

Teny Pinkard's discussion of explanation in science and history raises some issues important for social science generally, as well as for history. I would like to focus on his analysis of the relationship between explanation and understanding, with the aim of reopening an issue which his treatment appears to have closed. In doing so, I hope to encourage further analysis of the problem of how we ‘understand’. My own discussion of this issue will be brief, moving only a little beyond (...) Pinkard's. Primarily. I hope to show that ‘understanding’ is in fact a problem, and one that cannot merely be viewed as secondary to an analysis of ‘explanation’. (shrink)

This article contrasts a secular definition of “academic freedom” with a Catholic model, where freedom of discussion and investigation is one component of a wider process that leads to the Church’s judgment about a particular teaching. Three questions arise about academic freedom: (1) its purpose and goal, (2) its limits, and (3) its relationship to the Church. While there is sometimes tension between some people and the teaching office, fruitful doctrinal development usually takes place within the—sometimes heated—world of theological discussion. (...) A postscript describes the mandatum as a concrete expression of the intrinsic role that the magisterium has in Catholic theology and the role of the university and faculty in relation to the wider church. (shrink)

Frank Tipler's The Physics of Immortality provides abundant cause for intellectual offense—including challenges to physics, to theology, and, seemingly, to common sense. Few philosophical conundrums remain unaddressed. Still, the book is stimulating and well presented.

Stefanie Rocknak has written an ambitious and challenging book1 in which she argues for a new interpretation of Hume's account of how we come to believe in external objects, and what it is we believe in. I am hampered by the fact that she and I seem to agree on so little. Thus, my criticisms run the danger of simply not seeing what she is up to.A preliminary terminological point: where Rocknak uses the word "object," I will often use the (...) word "body," since I think Hume sometimes uses "object" in a more general sense that includes perceptions.If I understand correctly, Rocknak's Hume argues that we come to believe in bodies through a special kind of causal reasoning. We reason what must exist in order to cause... (shrink)

This article explores the use of intoxicants by a community of Kulina Indians in western Brazil. I suggest that Kulina intoxication through alcohol, tobacco, and ayahuasca is best understood as a form of semiotic appropriation of the identity of cosmological “others,” including animal spirits, creator beings, other Indian groups, and Brazilians. I consider how embodying practices, such as song and physical movement, enhance the experience of being an “alter,” facilitated by the alterations in consciousness produced by intoxicants.

An assertion of high conditional probability or, more briefly, an HCP assertion is a statement of the type: The conditional probability of B given A is close to one. The goal of this paper is to construct logics of HCP assertions whose conclusions are highly likely to be correct rather than certain to be correct. Such logics would allow useful conclusions to be drawn when the premises are not strong enough to allow conclusions to be reached with certainty. This goal (...) is achieved by taking Adams' (1966) logic, changing its intended application from conditionals to HCP assertions, and then weakening its criterion for entailment. According to the weakened entailment criterion, called the Criterion of Near Surety and which may be loosely interpreted as a Bayesian criterion, a conclusion is entailed if and only if nearly every model of the premises is a model of the conclusion. The resulting logic, called NSL, is nonmonotonic. Entailment in this logic, although not as strict as entailment in Adams' logic, is more strict than entailment in the propositional logic of material conditionals. Next, NSL was modified by requiring that each HCP assertion be scaled; this means that to each HCP assertion was associated a bound on the deviation from 1 of the conditional probability that is the subject of the assertion. Scaling of HCP assertions is useful for breaking entailment deadlocks. For example, it it is known that the conditional probabilities of C given A and of - C given B are both close to one but the bound on the former's deviation from 1 is much smaller than the latter's, then it may be concluded that in all likelihood the conditional probability of C given A ∧ B is close to one. The resulting logic, called NSL-S, is also nonmonotonic. Despite great differences in their definitions of entailment, entailment in NSL is equivalent to Lehmann and Magidor's rational closure and, disregarding minor differences concerning which premise sets are considered consistent, entailment in NSL-S is equivalent to entailment in Goldszmidt and Pearl's System-Z⁺. Bacchus, Grove, Halpern, and Koller proposed two methods of developing a predicate calculus based on the Criterion of Near Surety. In their randomstructures method, which assumed a prior distribution similar to that of NSL, it appears possible to define an entailment relation equivalent to that of NSL. In their random-worlds method, which assumed a prior distribution dramatically different from that of NSL, it is known that the entailment relation is different from that of NSL. (shrink)

In this essay I present a statement of Quine's indeterminacy thesis in its general form. It is shown that the thesis is not about difficulties peculiar to so-called "radical translation." It is a general thesis about meaning and reference with important consequences for any theory of our theories and beliefs. It is claimed that the thesis is inconsistent with Quine's realism, his doctrine of the relativity of reference, and that the argument for the thesis has the consequence that the concept (...) of stimulus meaning is empty. The sense in which linguistic science, as a branch of behavioral science, is "part of physics" is discussed. An alternative to Quine's view of the nature and content of linguistic science is proposed. It is shown to be consistent with Quine's assumptions concerning the legitimate scope of behavioral science and not to involve the notions of analyticity, synonymy and "prevalent attitudes toward meaning, idea and proposition" ([9], p. 304) rejected by Quine. (shrink)

In Hume's True Scepticism, I offer a new interpretation of David Hume's epistemology and philosophy of mind as presented in A Treatise of Human Nature.1 I approach this task by developing what I take to be the first comprehensive2 investigation of Part 4 of Book 1. The arguments Hume offers there have frequently been addressed by the secondary literature in a piecemeal fashion, especially his account of personal identity and of our belief in the external world. But I argue in (...) HTS that they should be read as a sustained investigation of the human temptation to form philosophical systems. Consider its title: "Of the sceptical and other systems of philosophy". Hume, I suggest, is... (shrink)

A view from deep inside the trenches of environmental policy formation leads me to conclude that, ironically, despite the failure of environmental ethics to penetrate public policy discourses, ethical analyses of environmental problems still appear to be more than ever vitally crucial to improving environmental decision making.

The Hollow Core of Constitutional Theory is the first major defense of the central role of the Framers' intentions in constitutional interpretation to appear in years. This book starts with a reminder that, for virtually all of Western legal history, when judges interpreted legal texts, their goal was to identify the lawmaker's will. However, for the past fifty years, constitutional theory has increasingly shifted its focus away from the Framers. Contemporary constitutional theorists, who often disagree with each other about virtually (...) everything else, have come to share the view that the Framers' understandings are unknowable and irrelevant. This book shows why constitutional interpretation needs to return to its historical core inquiry, which is a search for the Framers' intentions. Doing so is practically feasible, theoretically defensible, and equally important not only for discovering the original meaning, but also for deciding how to apply the Constitution today. (shrink)

A biological explanation for the dependence of genome-wide mutation-rate variation on local base context is now becoming clearer. The proportions of G + C relative to A + T—expressed as GC%—is a species-specific DNA character. The frequencies of these single bases correlate with frequencies of corresponding oligonucleotides that are more-sensitive indicators of species specificity. Thus, when k = 3 there are 64 possible trinucleotide sequences and a GC%-rich species has a high frequency of GC-rich 3-mers. Closely related species have similar (...) k-mer patterns. For distantly related species, even if happening to have the same GC% values, k-mer patterns are widely discordant. Conventionally, a base substitution mutation is viewed as a chemical 1-mer phenomenon. However, the selective difference by which the corresponding mutation is scored usually relates to context. Thus, an A to U codon mutation in sickle cell anemia, rather than attracting an anticodon in a structural loop of glutamate tRNA, pairs with the more complementary anticodon loop of valine tRNA. Likewise, a recent statistical analysis of genome-wide mutation-rate variation supports the view that a failure of discordant DNA loops to pair at meiosis can initiate and/or sustain the speciation process. Such disharmony among base patterns may have unknowingly been hinted at by geneticist William Bateson who invoked a music metaphor when considering speciation mechanisms. (shrink)

We show that Blackwell determinacy in L(R) implies determinacy in L(R).