The concept of a reason is now central to many areas of contemporary philosophy. Key theses in ethics, epistemology, political philosophy, philosophy of action, and the philosophy of the emotions, among others, have come to be framed in terms of reasons. And yet, despite their centrality, theorists seem to take inconsistent things for granted about how reasons work, what kinds of things can be reasons, what reasons favor, and more. Somehow reasons have come to be both indispensable and impenetrable. -/- (...) The Fundamentals of Reasons offers a comprehensive introduction to the philosophy of reasons. Focusing on the twin roles of reasons in explanation and deliberation, the book not only emphasizes what has made reasons central across philosophy but it also explores why philosophers have such incompatible pictures about what reasons are and how they work. Working from the inside out, Howard and Schroeder identify contentious assumptions about not only the internal structure of reasons but also their relationship to other important concepts, and then show how these contentious assumptions shape the many downstream applications of reasons in ethics, epistemology, political philosophy, and beyond. -/- This mildly opinionated exploration of key questions about the significance and nature of reasons helps the reader to navigate this important part of the philosophical landscape and to get clearer about why reasons seem important and what their import, ultimately, is. (shrink)

James A. Diefenbeck, Wayward Reflections on the History ofPhilosophyThomas R. Flynn Sartre, Foucault and Historical Reason. Volume 1:Toward an Existential Theory of HistoryMark Golden and Peter Toohey Inventing Ancient Culture:Historicism, Periodization and the Ancient WorldZenonas Norkus Istorika: Istorinis IvadasEverett Zimmerman The Boundaries of Fiction: History and theEighteenth‐Century British Novel.

Recently, as I have become more computer-literate, I have noticed some interesting parallels between computer mechanisms and Aquinas’ metaphysics of angelic faculties. The present essay expands on some of the analogies which Aquinas himself, though no proponent of AI theory, might have found interesting.

A reexamination of democracy, which during the eighteenthcentury Enlightenment seemed to offer a much-desired escape from arbitrary class structures and oppressive governments, but has not proven to be a sure formula or a simple solution. An awareness of the true complexities of democracy requires an understanding of a perennial dialectic residing at the heart of democracy, and manifesting itself in specific dialectical relationships: between elitism and populism, liberty and equality, smallness and bigness, religion and secular life, politics and economics, etc. (...) This book argues that such dialectical relationships, originally most explicit in particular nations, are also manifest in international relations. (shrink)

Like Henry Harris, I began doing intensive research on Hegel's Phenomenology of Spirit in the mid-sixties. I recall going through all the chapters as a graduate student during one academic year, and looking around for commentaries. The only English-language commentary available was Loewenberg's Hegel's Phenomenology: Dialogues in the Life of Mind, which was suggestive of the dialectic taking place in the book, but not much help in getting over the “rough spots”. This gave me an incentive to work through Jean (...) Hyppolite's commentary, not yet translated into English, with my basic reading-knowledge of French. My 1976 Hegel's Phenomenology, Part I: Analysis and Commentary was one of the first in a long line of Anglophone commentaries. Harris in his introduction to Vol. I. mentions this effort at “analysis”, along with Findlay's “analysis” accompanying the 1977 Miller translation of the Phenomenology, as incentives for the inclusion of his own improved running analysis in the present commentary. I have included discussions of numerous partial or complete commentaries on Hegel's Phenomenology in review articles published in 1971 in the American Philosophical Quarterly and Teorema, in 1979 in the American Philosophical Quarterly, and in 1981 in Hegel-Studien. Harris has the advantage of producing the most recent of all these commentaries, and in a way offers us a compendium of everything that has been done on the Phenomenology. His analysis and commentary includes a survey of the literature, in which almost all previous laborers in the field can find themselves commended or criticized in the endnotes. Thus I find comments like “Kainz has completely misunderstood the argument here”, “This is a point which Kainz has grasped more definitely than most commentators”, “[Kainz] does not deserve the brickbat Flay hurls at him”, and so forth. Other commentators, living and dead – Flay, Pöggeler, Navickas, Kenneth and Merold Westphal, Heidegger, Lauer, Werner Becker, Kojève, Wahl, Hyppolite, Labarrière, Bonsiepen, Forster, Shklar, Solomon, Werner Marx, and Robert Williams — are similarly discussed and critiqued. For some of us Anglophone commentators, such remarks may seem like red marks on essays from a patient professor. But certainly no one will mind, since Harris has spent more time and energy on this very specialized project than any of us. In fact, some former commentators almost have a “conflict of interest” in reviewing Harris' work, since so many of us have benefited at various points in our research from Harris' personal support and criticism. But in academics, as in life, mentors cannot always be assured of loyalty. (shrink)

Her importance seems to hinge on the fact that she is both a symbol and a historical reality.

The physics and metaphysics of identity and individuality Content Type Journal Article DOI 10.1007/s11016-010-9463-7 Authors Don Howard, Department of Philosophy and Graduate Program in History and Philosophy of Science, University of Notre Dame, Notre Dame, IN 46556, USA Bas C. van Fraassen, Philosophy Department, San Francisco State University, 1600 Holloway Avenue, San Francisco, CA 94132, USA Otávio Bueno, Department of Philosophy, University of Miami, Coral Gables, FL 33124, USA Elena Castellani, Department of Philosophy, University of Florence, Via Bolognese 52, (...) 50139 Florence, Italy Laura Crosilla, Department of Pure Mathematics, School of Mathematics, University of Leeds, Leeds, LS2 9JT UK Steven French, Department of Philosophy, University of Leeds, Leeds, UK Décio Krause, Department of Philosophy, Federal University of Santa Catarina, 88040-900 Campus Trindade, Florianópolis, SC Brazil Journal Metascience Online ISSN 1467-9981 Print ISSN 0815-0796. (shrink)

Inquisitiveness has been found to be a characteristic of successful global managers. The paper distinguishes inquisitiveness from purposeless curiosity andshows that it is a virtue. It suggests that the practice of inquisitiveness is akin to abduction, the method of reasoning described by Charles S. Peirce distinct from deduction and induction, and essential to creativity. It then suggests that an enhanced capacity for inquisitiveness and abduction will increase the capacity for moral imagination and hence improve moral decision-making (and perhaps moral behaviour).

Aristotle's Account of the Virtue of Temperance in Nicomachean Ethics III. 1 o- 11 HOWARD J. CURZER 1. INTRODUCTION maNY ?ONTEMPOX~RY SOCIAL eROBL~S arise from inappropriate indulgence in food, drink, and/or sex. Temperance is the Aristotelian virtue which governs these three things, and Aristotle's account of temperance contains important insights and useful distinctions. Yet Aristotle's account of temperance has been surprisingly neglected, despite the resurgence of virtue ethics. I shall remedy this neglect by providing a passage- by-passage commentary on (...) Aristotle's account of temperance in Nicomachean Ethics III. lO-11. I shall describe the sphere of temperance and Aristotle's distinctions among the character traits of temperance, self-indulgence, insensi- bility, continence, incontinence, and brutishness. I shall also describe the pas- sions and parameters of temperance and argue that Aristotle's account of temperance is compatible with his doctrine of the mean. My interpretation includes several controversial claims. For example, I maintain that Aristote- lian temperance governs not only the enjoyment of certain tactile pleasures, but also the desire for these pleasures. Aristotle's account clashes with common sense and with his own architec- tonic at several points. For example, he maintains that a person is intemperate only if he or she goes wrong.. (shrink)

In considering the development and course of the American welfare state, there are some places which are better starting points than others. One such place is the State Street corridor, the series of high-rise Chicago Housing Authority public-housing projects which loom over Lake Michigan. Most Chicagoans, like their counterparts in other cities, have become inured to conditions there: a murder rate far in excess of that of the city as a whole, a society of unemployed single mothers, deferred maintenance that (...) makes stairwells, plazas, and elevators places of danger. Author Alex Kotlowitz decribes the situation of a mother of two boys in Chicago's Henry Horner Homes: “She lived in daily fear that something might happen to her young ones.… Already that year, 57 children had been killed in the city, five in the Horner area, including two, aged eight and six, who died from smoke inhalation when firefighters had to climb the 14 stories to their apartment. Both of the building's elevators were broken.”. (shrink)

The levels of different classes of mitochondrially encoded transcripts are developmentally regulated in sea urchin embryos, as a result of selection between mutually exclusive synthetic pathways. I propose a simple model to explain these observations, based on a dual role for mitochondrial ribosomes and translation factors in RNA synthesis as well as in translation. This effect may be exerted either at the transcriptional or post‐transcriptional level (or both), and is potentially generalizable to mammalian mtDNA and to other systems.

‘It is not likely that anything absolutely new can be added to the interpretation of this familiar poem.’ So G. L. Hendrickson forty five years ago. It need scarcely be noted that in spite of these cautionary words much has been written on this ode in the intervening years. With hesitation I add here a few words on what seems to me an overlooked yet central aspect of this poem.

Bailey posed the problem succinctly and clearly: ‘Though you can be said to “fashion a dream for yourself”, it is not easy to see how you can do it for someone else.’ He agrees with Giussani: somnia = ineptae fabulae, which is unexceptionable. But in fact Bailey's objection to the ‘literal’ meaning of the text is baseless. Dream control was indeed practised in antiquity.

Servius was surely not the first to show discomfort with Vergil's choice of the word violaverit. Observing that the simile in lines 67–8 derives from Homer , he seems to be apologizing for Vergil when he explains that the poet's violaverit translates Homer's νινη. And discomfort there should be. The notion of ‘tainting, spoiling, damaging, defiling’ that violare should carry seems out of place both for the ivory-image and for the picture of the beautiful girl. Modern commentators have been no (...) less troubled than Servius. Unwilling, however, to see Vergil as blindly enslaved to Homer, they have offered another explanation: violare here is tied to the violentia of her lover Turnus. ‘Vergil connects the violentia of Turnus with the staining of the ivory in the simile used to describe Lavinia's blush.’ should like to add a third explanation for Vergil's choice of violare. (shrink)

Cranial measurements and somatotype indices were compared in two groups of patients, one with recurrent depressive illness and the other suffering from a first solitary attack of depression. Certain statistically significant differences in stature, somatotype and cranial measurements emerged; the group with recurrent episodes of depression tended to be shorter and more brachycephalic than those with solitary episodes of depression.

Interaction of ligands such as epidermal growth factor and interferon‐γ with the extracellular domains of their plasma membrane receptors results in internalization followed by translocation into the nucleus of the ligand and/or receptor. There has been reluctance, however, to ascribe signaling importance to this, the focus instead being on second messenger pathways, including mobilization of kinases and inducible transcription factors (TFs). The latter, however, fails to explain the fact that so many ligands stimulate the same second messenger cascades/TFs, and yet (...) show distinct gene activation profiles. This is particularly apt in the case of the seven STAT TFs that are held to be the mediators of the distinct cellular functions of over 60 ligands. The current review focuses on five representative nuclear localizing ligands for which there is documentation of translocation into the cytosol and nucleus through well‐characterized pathways, in addition to a role in gene activation by ligand/receptor in the nucleus. BioEssays 26:993‐1004, 2004. © 2004 Wiley Periodicals, Inc. (shrink)

The first full-length study in English of Gassendi's life and work. I. The Man and his Work - II. Gassendi the Critic (separate chapters devoted to the Aristoteleans, Herbert of Cherbury and Descartes) - III. Gassendi the Philosopher. (Bibliotheca Humanistica & Reformatorica, Vol. XXXIV).