26 found
Order:
Disambiguations
Daniel J. Hurst [22]Daniel Hurst [5]
  1.  38
    Genetic disenhancement and xenotransplantation: diminishing pigs’ capacity to experience suffering through genetic engineering.Daniel Rodger, Daniel J. Hurst, Christopher A. Bobier & Xavier Symons - 2024 - Journal of Medical Ethics 50 (11):729-733.
    One objection to xenotransplantation is that it will require the large-scale breeding, raising and killing of genetically modified pigs. The pigs will need to be raised in designated pathogen-free facilities and undergo a range of medical tests before having their organs removed and being euthanised. As a result, they will have significantly shortened life expectancies, will experience pain and suffering and be subject to a degree of social and environmental deprivation. To minimise the impact of these factors, we propose the (...)
    Direct download (3 more)  
     
    Export citation  
     
    Bookmark   5 citations  
  2.  31
    Zooming in on Justice: The Case for Virtual Bioethics Conferencing.Bruce P. Blackshaw, Daniel Rodger & Daniel J. Hurst - 2024 - American Journal of Bioethics 24 (4):60-62.
    In their target article, “Proposed Principles for International Bioethics Conferencing: Anti-Discriminatory, Global, and Inclusive,” Jecker et al. (2024) highlight the growing international scope o...
    Direct download (2 more)  
     
    Export citation  
     
    Bookmark   1 citation  
  3.  7
    Argument for allowing first-in-human cardiac xenotransplantation clinical trials in paediatric patients.Daniel J. Hurst, Anthony Merlocco, Luz A. Padilla & Chris Bobier - 2025 - Journal of Medical Ethics 51 (3):168-169.
    We read with interest the recent article on criteria for patient selection of cardiac xenotransplantation by Kögel et al.1 The authors recognise the benefits and concerns of first developing xenotransplantation trials in children (or at least concurrent development). They conclude that, based on (1) the vulnerable nature of children and (2) the observation that ‘the benefits of cardiac xenotransplantation have never been systematically proven in humans,’ that the ‘very first clinical trials should be conducted with adult patients.’ This is a (...)
    Direct download (3 more)  
     
    Export citation  
     
    Bookmark   1 citation  
  4.  8
    Challenges in Paediatric Xenotransplantation: Ethical Components Requiring Distinct Attention in Children and Obligations to Patients and Society.Anthony Merlocco & Daniel J. Hurst - forthcoming - Journal of Bioethical Inquiry:1-14.
    The transplantation of non-human organs into humans, or xenotransplantation (XTx), has recently garnered new attention and is being developed to help address the problem of organ scarcity in transplantation. Ethical issues surrounding XTx have been studied since initial interest arose decades ago and have experienced renewed discussion in the literature. However, the distinct and relevant differences when applied to children has largely been overlooked with few groups attending to the concerns that XTx in children raises. In this paper, we explore (...)
    Direct download (3 more)  
     
    Export citation  
     
    Bookmark   1 citation  
  5.  37
    Paediatric xenotransplantation clinical trials and the right to withdraw.Daniel J. Hurst, Luz A. Padilla, Wendy Walters, James M. Hunter, David K. C. Cooper, Devin M. Eckhoff, David Cleveland & Wayne Paris - 2020 - Journal of Medical Ethics 46 (5):311-315.
    Clinical trials of xenotransplantation (XTx) may begin early in the next decade, with kidneys from genetically modified pigs transplanted into adult humans. If successful, transplanting pig hearts into children with advanced heart failure may be the next step. Typically, clinical trials have a specified end date, and participants are aware of the amount of time they will be in the study. This is not so with XTx. The current ethical consensus is that XTx recipients must consent to lifelong monitoring. While (...)
    Direct download (5 more)  
     
    Export citation  
     
    Bookmark   2 citations  
  6.  27
    Restoring a reputation: invoking the UNESCO Universal Declaration on Bioethics and Human Rights to bear on pharmaceutical pricing.Daniel J. Hurst - 2017 - Medicine, Health Care and Philosophy 20 (1):105-117.
    In public health, the issue of pharmaceutical pricing is a perennial problem. Recent high-profile examples, such as the September 2015 debacle involving Martin Shkreli and Turing Pharmaceuticals, are indicative of larger, systemic difficulties that plague the pharmaceutical industry in regards to drug pricing and the impact it yields on their reputation in the eyes of the public. For public health ethics, the issue of pharmaceutical pricing is rather crucial. Simply, individuals within a population require pharmaceuticals for disease prevention and management. (...)
    Direct download (2 more)  
     
    Export citation  
     
    Bookmark   2 citations  
  7.  33
    The utility of a bioethics doctorate: results of a survey of graduates and students having completed All-but-Dissertation Requirements (ABD) from US bioethics doctoral programs.Daniel J. Hurst, Jordan Potter, Ariel Clatty & Joris Gielen - 2021 - International Journal of Ethics Education 7 (1):21-34.
    In the United States, the field of bioethics has expanded over the last two decades. Several institutions offer graduate-level training at both the masters and doctoral level. However, a lack of published literature on the outcomes of doctoral training in bioethics from the perspective of graduates exists. Researchers conducted an online survey of doctoral students who had finished all doctoral requirements but their dissertation, as well as doctoral graduates, of four US-based institutions to ascertain their perspectives on a number of (...)
    Direct download (3 more)  
     
    Export citation  
     
    Bookmark   1 citation  
  8. Xenotransplantation: A historical–ethical account of viewpoints.Daniel Rodger, Daniel J. Hurst & David K. C. Cooper - forthcoming - Xenotransplantation.
    Formal clinical trials of pig-to-human organ transplant—known as xenotransplantation—may begin this decade, with the first trials likely to consist of either adult renal transplants or pediatric cardiac transplant patients. Xenotransplantation as a systematic scientific study only reaches back to the latter half of the 20th century, with episodic xenotransplantation events occurring prior to that. As the science of xenotransplantation has progressed in the 20th and 21st centuries, the public's knowledge of the potential therapy has also increased. With this, there have (...)
    Direct download (2 more)  
     
    Export citation  
     
    Bookmark  
  9.  24
    Battlefield Triage.Christopher Bobier & Daniel Hurst - 2024 - Voices in Bioethics 10.
    Photo ID 222412412 © US Navy Medicine | Dreamstime.com ABSTRACT In a non-military setting, the answer is clear: it would be unethical to treat someone based on non-medical considerations such as nationality. We argue that Battlefield Triage is a moral tragedy, meaning that it is a situation in which there is no morally blameless decision and that the demands of justice cannot be satisfied. INTRODUCTION Medical resources in an austere environment without quick recourse for resupply or casualty evacuation are often (...)
    No categories
    Direct download (2 more)  
     
    Export citation  
     
    Bookmark  
  10. In defense of xenotransplantation research: Because of, not in spite of, animal welfare concerns.Christopher Bobier, Daniel Rodger, Daniel J. Hurst & Adam Omelianchuk - forthcoming - Xenotransplantation.
    It is envisioned that one day xenotransplantation will bring about a future where transplantable organs can be safely and efficiently grown in transgenic pigs to help meet the global organ shortage. While recent advances have brought this future closer, worries remain about whether it will be beneficial overall. The unique challenges and risks posed to humans that arise from transplanting across the species barrier, in addition to the costs borne by non-human animals, has led some to question the value of (...)
    Direct download  
     
    Export citation  
     
    Bookmark  
  11.  14
    Clarifying Dual Use Research of Concern.Christopher Bobier & Daniel J. Hurst - 2024 - Philosophy and Technology 37 (4):1-14.
    Significant attention is paid to what is coined _dual use research (DUR)_, or research that has the potential to benefit and harm humanity, and _dual use research of concern (DURC)_, a particular subset of DUR that is reasonably anticipated to be a safety and security concern if misapplied. Despite growing attention to DUR and DURC, there is entrenched and often overlooked ambiguity over these terms, and thereby, the challenges they pose. Conceptual clarity is much needed and is the rationale behind (...)
    No categories
    Direct download (3 more)  
     
    Export citation  
     
    Bookmark  
  12.  7
    Collective Consent to Xenotransplantation: A Critical Appraisal.Christopher Bobier, Adam Omelianchuk, Daniel Rodger & Daniel J. Hurst - 2025 - Public Health Ethics 18 (1).
    Solid organ xenotransplantation may have the potential to help address the shortage of organs for transplantation. There is concern, however, that a novel zoonotic disease could be transmitted from the source organ to the human recipient, and then from the recipient to others. Theoretically, this could result in an epidemic or pandemic. Because of this potential risk, it has been argued that collective consent is required. Our goal is to critically evaluate the claim that collective consent is necessary for xenotransplantation (...)
    Direct download (3 more)  
     
    Export citation  
     
    Bookmark  
  13.  23
    The Utility of a Bioethics Doctorate: Graduates’ Perspectives.Jordan Potter, Daniel Hurst, Christine Trani, Ariel Clatty & Sarah Stockey - 2019 - Journal of Medical Humanities 40 (4):473-487.
    Each year, many young professionals forego advanced education in the traditional doctoral programs of medicine, law, and philosophy in favor of pursuing a PhD or professional doctorate in bioethics or healthcare ethics that is offered by several major institutes of higher education across the United States. These graduates often leverage their degrees into careers within the broader field of bioethics. As such, they represent a growing percentage of professional bioethicists in both academia and healthcare nationwide. Given the significant role that (...)
    Direct download (2 more)  
     
    Export citation  
     
    Bookmark   1 citation  
  14.  6
    Dual use research and artificial intelligence.Daniel Hurst & Christopher Bobier - forthcoming - AI and Society:1-2.
  15.  28
    Xenograft recipients and the right to withdraw from a clinical trial.Christopher Bobier, Daniel J. Hurst, Daniel Rodger & Adam Omelianchuk - 2024 - Bioethics 38 (4):308-315.
    Preclinical xenotransplantation research using genetically engineered pigs has begun to show some promising results and could one day offer a scalable means of addressing organ shortage. While it is a fundamental tenet of ethical human subject research that participants have a right to withdraw from research once enrolled, several scholars have argued that the right to withdraw from xenotransplant research should be suspended because of the public health risks posed by xenozoonotic transmission. Here, we present a comprehensive critical evaluation of (...)
    Direct download (2 more)  
     
    Export citation  
     
    Bookmark  
  16.  28
    Is There a Business Case for Constitutive Duties of For-Profit Research Funders?Daniel J. Hurst - 2018 - American Journal of Bioethics 18 (11):35-37.
    Direct download (4 more)  
     
    Export citation  
     
    Bookmark   1 citation  
  17.  10
    Defending genetic disenhancement in xenotransplantation.Daniel Rodger, Daniel J. Hurst, Christopher A. Bobier & Xavier Symons - 2024 - Journal of Medical Ethics 50 (11):742-743.
    We read the four commentaries on our article with much interest.1 Each response provides stimulating discussion, and below we have attempted to respond to specific issues that they have raised. We regret that we are not able to respond point-by-point to each of them. However, before our responses, it may benefit the reader if we briefly summarise the claims in our article. First, we hold two presuppositions: (1) xenotransplantation research will inevitably continue for the foreseeable future, and (2) causing suffering (...)
    Direct download (3 more)  
     
    Export citation  
     
    Bookmark  
  18.  9
    Battlefield Triage: A Resolvable Moral Tragedy.Christopher Bobier & Daniel Hurst - 2024 - Voices in Bioethics 10:75-83.
    No categories
    Direct download  
     
    Export citation  
     
    Bookmark  
  19.  24
    A Re-examination of Organ Sale and its Challenges.Daniel J. Hurst - 2015 - Eubios Journal of Asian and International Bioethics 25 (2):57-63.
    There is a global consensus of ethicists, politicians, physicians, and international documents that reject any sort of market in human organs. Indeed, this issue has received much attention in the literature in the past few decades, with the majority of commentators placing a high correlation between the sale of organs and financial exploitation. While this argument may be tenable, this analysis seeks to draw out further implications of organ sale, including the idea of moralistic exploitation and the concept that providing (...)
    No categories
    Direct download  
     
    Export citation  
     
    Bookmark   1 citation  
  20.  3
    Xenotransplantation as a business solution to the organ shortage.Christopher Bobier, Richard B. Gibson, Anthony Merlocco, Daniel Rodger & Daniel J. Hurst - forthcoming - Bioethics.
    Xenotransplantation has the potential to alter the U.S. transplant system in profound ways. However, this emerging “spare parts” solution spearheaded by biotechnology companies raises concerns about its impact on the organ shortage, healthcare systems, population health, and health inequalities. We contend that xenotransplantation may have limited benefits in improving health, could prove prohibitively expensive for many, and may divert resources away from proven public health measures. Additionally, it carries the risk of perpetuating stigma. Xenotransplantation may thereby exacerbate existing healthcare inequities (...)
    Direct download (2 more)  
     
    Export citation  
     
    Bookmark  
  21.  35
    Benefit Sharing in a Global Context: Working Towards Solutions for Implementation.Daniel J. Hurst - 2016 - Developing World Bioethics 17 (2):70-76.
    Due to the state of globalized clinical research, questions have been raised as to what, if any, benefits those who contribute to research should receive. One model for compensating research participants is “benefit sharing,” and the basic premise is that, as a matter of justice, those who contribute to scientific research should share in its benefits. While incorporated into several international documents for over two decades, benefit sharing has only been sparsely implemented. This analysis begins by addressing the concept of (...)
    Direct download  
     
    Export citation  
     
    Bookmark  
  22.  27
    (1 other version)Barriers to Patient Involvement in Decision-Making in Advanced Cancer Care: Culture as an Amplifier.Daniel Hurst, Jordan Potter, Persis Naumann, Jasia Baig, Manjulata Evatt, Joan Lockhart & Joris Gielen - forthcoming - Narrative Inquiry in Bioethics.
    No categories
    Direct download (2 more)  
     
    Export citation  
     
    Bookmark  
  23.  8
    Colloquy.Daniel J. Hurst - 2018 - The National Catholic Bioethics Quarterly 18 (1):15-16.
    No categories
    Direct download  
     
    Export citation  
     
    Bookmark  
  24.  11
    Transitioning from Urban to Rural: Challenges Seen through the Eyes of a Recent Bioethics Doctoral Graduate.Daniel J. Hurst - 2019 - Narrative Inquiry in Bioethics 9 (2):91-93.
    No categories
    Direct download (2 more)  
     
    Export citation  
     
    Bookmark  
  25.  30
    Full Collection of Personal Narratives.Ryan McCarthy, Joe Asaro, Daniel J. Hurst, Anonymous One, Susan Wik, Kathryn Fausch, Anonymous Two, Janet Lynne Douglass, Jennifer Hammonds, Gretchen M. Spars, Ellen L. Schellinger, Ann Flemmer, Connie Byrne-Olson, Sarah Howe-Cobb, Holly Gumz, Rochelle Holloway, Jacqueline J. Glover, Lisa M. Lee, Ann Freeman Cook & Helena Hoas - 2019 - Narrative Inquiry in Bioethics 9 (2):89-133.
    No categories
    Direct download (2 more)  
     
    Export citation  
     
    Bookmark  
  26.  44
    Ethics education in US and Canadian family medicine residency programs: a review of the literature. [REVIEW]Daniel J. Hurst - 2018 - International Journal of Ethics Education 4 (1):73-82.
    The importance of bioethics education as a valuable tool to be responsive to medicine’s complexities is affirmed by graduate medical education accreditation bodies and professional organizations alike. The Accreditation Council for Graduate Medical Education, the body that accredits the majority of medical residency and fellowship programs in the United States, affirms the importance of ethics training for physicians in training. How this is accomplished is largely left to the prerogative of individual programs to manage, as benchmarks or milestones to ascertain (...)
    No categories
    Direct download (2 more)  
     
    Export citation  
     
    Bookmark