Hodgkin and Huxley’s model of the action potential is an apparent dream case of covering‐law explanation in biology. The model includes laws of physics and chemistry that, coupled with details about antecedent and background conditions, can be used to derive features of the action potential. Hodgkin and Huxley insist that their model is not an explanation. This suggests either that subsuming a phenomenon under physical laws is insufficient to explain it or that Hodgkin and Huxley were wrong. I defend Hodgkin (...) and Huxley against Weber’s heteronomy thesis and argue that explanations are descriptions of mechanisms. †To contact the author, please write to: Department of Philosophy, Philosophy‐Neuroscience‐Psychology Program, Washington University in St. Louis, One Brookings Drive, Wilson Hall, St. Louis, MO 63130; e‐mail: [email protected]. (shrink)

Bernard Stiegler’s contributions to political philosophy in the presence of technology are honored and complemented by imagining an encounter with the thought of Leo Strauss. The concept of sovereignty is taken as pivotal. Notions of sovereignty find expression not only in nation state politics but also in engineering and technology. Pierre Manent calls attention to further roots in Christian theology. The complexities and challenges of this interweaving point suggest the need for a “Tractatus Politico-Technologicus.”.

In the Global Burden of Disease study, disease burden is measured as disability-adjusted life years (DALYs). The paramount assumption of the DALY is that it makes sense to aggregate years lived with disability (YLDs) and years of life lost (YLLs). However, this is not smooth sailing. Whereas morbidity (YLD) is something thathappens toan individual, loss of life itself (YLL) occurs when that individual’s life has ended. YLLs quantify something that involves no experience and does not take place among living individuals. (...) This casts doubt on whether the YLL is an individual burden at all. If not, then YLDs and YLLs are incommensurable. There are at least three responses to this problem, only one of which is tenable: a counterfactual account of harm. Taking this strategy necessitates a re-examination of how we count YLLs, particularly at the beginning of life. (shrink)

In this, his most influential work, legal theorist and political philosopher Carl Schmitt argues that liberalism’s basis in individual rights cannot provide a reasonable justification for sacrificing oneself for the state—a critique as cogent today as when it first appeared. George Schwab’s introduction to his translation of the 1932 German edition highlights Schmitt’s intellectual journey through the turbulent period of German history leading to the Hitlerian one-party state. In addition to analysis by Leo Strauss and a foreword by Tracy (...) B. Strong placing Schmitt’s work into contemporary context, this expanded edition also includes a translation of Schmitt’s 1929 lecture “The Age of Neutralizations and Depoliticizations,” which the author himself added to the 1932 edition of the book. An essential update on a modern classic, The Concept of the Political, Expanded Edition belongs on the bookshelf of anyone interested in political theory or philosophy. (shrink)

We establish a probabilized version of modus tollens, deriving from p(E|H)=a and p()=b the best possible bounds on p(). In particular, we show that p() 1 as a, b 1, and also as a, b 0. Introduction Probabilities of conditionals Conditional probabilities 3.1 Adams' thesis 3.2 Modus ponens for conditional probabilities 3.3 Modus tollens for conditional probabilities.

Archytas of Tarentum is one of the three most important philosophers in the Pythagorean tradition, a prominent mathematician, who gave the first solution to the famous problem of doubling the cube, an important music theorist, and the leader of a powerful Greek city-state. He is famous for sending a trireme to rescue Plato from the clutches of the tyrant of Syracuse, Dionysius II, in 361 BC. This 2005 study was the first extensive enquiry into Archytas' work in any language. It (...) contains original texts, English translations and a commentary for all the fragments of his writings and for all testimonia concerning his life and work. In addition there are introductory essays on Archytas' life and writings, his philosophy, and the question of authenticity. Carl A. Huffman presents an interpretation of Archytas' significance both for the Pythagorean tradition and also for fourth-century Greek thought, including the philosophies of Plato and Aristotle. (shrink)

We initiate the reverse mathematics of general topology. We show that a certain metrization theorem is equivalent to Π2 1 comprehension. An MF space is defined to be a topological space of the form MF(P) with the topology generated by $\lbrace N_p \mid p \in P \rbrace$ . Here P is a poset, MF(P) is the set of maximal filters on P, and $N_p = \lbrace F \in MF(P) \mid p \in F \rbrace$ . If the poset P is countable, (...) the space MF(P) is said to be countably based. The class of countably based MF spaces can be defined and discussed within the subsystem ACA0 of second order arithmetic. One can prove within ACA0 that every complete separable metric space is homeomorphic to a countably based MF space which is regular. We show that the converse statement, "every countably based MF space which is regular is homeomorphic to a complete separable metric space," is equivalent to Π2 1-CA0. The equivalence is proved in the weaker system Π1 1-CA0. This is the first example of a theorem of core mathematics which is provable in second order arithmetic and implies Π2 1 comprehension. (shrink)

Journal of Social Philosophy, EarlyView.

There is a phenomenon which has from of old and in a peculiar degree attracted the attention of social philosophers and practical economists, the fact of certain commodities (these being in advanced civilizations coined pieces of gold and silver, together subsequently with documents representing those coins) becoming universally acceptable media of exchange. It is obvious even to the most ordinary intelligence, that a commodity should be given up by its owner in exchange for another more useful to him. But that (...) every economic unit in a nation should be ready to exchange his goods for little metal disks apparently useless as such, or for documents representing the latter, is a procedure so opposed to the ordinary course of things, that we cannot well wonder if even a distinguished thinker like Savigny finds it downright 'mysterious.' It must not be supposed that the form of coin, or document, employed as current money, constitutes the enigma in this phenomenon. We may look away from these forms and go back to earlier stages of economic development, or indeed to what still obtains in countries here and there, where we find the precious metals in a uncoined state serving as the medium of exchange, and even certain other commodities, cattle, skins, cubes of tea, slabs of salt, cowrie shells, etc.; still we are confronted by this phenomenon, still we have to explain why it is that the economic man is ready to accept a certain kind of commodity, even if he does not need it, or if his need of it is already supplied, in exchange for all the goods he has brought to market, while it is none the less what he needs that he consults in the first instance, with respect to the goods he intends to acquire in the course of his transactions. And hence there runs, from the first essays of reflective contemplation of a social phenomena down to our own times, an uninterrupted chain of disquisitions upon the nature and specific qualities of money in its relation to all that constitutes traffic.. (shrink)

It has often been recommended that the differing probability distributions of a group of experts should be reconciled in such a way as to preserve each instance of independence common to all of their distributions. When probability pooling is subject to a universal domain condition, along with state-wise aggregation, there are severe limitations on implementing this recommendation. In particular, when the individuals are epistemic peers whose probability assessments are to be accorded equal weight, universal preservation of independence is, with a (...) few exceptions, impossible. Under more reasonable restrictions on pooling, however, there is a natural method of preserving the independence of any fixed finite family of countable partitions, and hence of any fixed finite family of discrete random variables. (shrink)

Upon entering the White House in 1933, President Franklin D. Roosevelt faced an ailing economy in the throes of the Great Depression and rushed to transform the country through recovery programs and legislative reform. By 1934, he began to send professional photographers to the state of West Virginia to document living conditions and the effects of his New Deal programs. The photographs from the Farm Security Administration Project not only introduced “America to Americans,” exposing a continued need for government intervention, (...) but also captured powerful images of life in rural and small town America.New Deal Photographs of West Virginia, 1934-1943 presents images of the state's northern and southern coalfields, the subsistence homestead projects of Arthurdale, Eleanor, and Tygart Valley, and various communities from Charleston to Clarksburg and Parkersburg to Elkins. With over one hundred and fifty images by ten FSA photographers, including Walker Evans, Marion Post Wolcott, Arthur Rothstein, and Ben Shahn, this collection is a remarkable proclamation of hardship, hope, endurance, and, above all, community. These photographs provide a glimpse into the everyday lives of West Virginians during the Great Depression and beyond. (shrink)

Study which takes seriously both the moral revelation of Christianity and the ethical alternatives of speculative philosophy.

Asserting that traditional Western religious groundings for ethics neither reach a modern international audience nor solve the interpersonal and global problems ...