The Aristotelian axiom that function follows form was beautifully instantiated in molecular biology by the discovery of DNA’s structure that immediately suggested how DNA might work as depository and vehicle for genetic information. However, later on molecular biology became infatuated with the gene that became the center of the universe. This gene-centered viewpoint is an obstacle for the emerging field of evo-devo aiming at finding the causal connections between evolution and biological development. Here it is argued that molecular biology must (...) reject the narrow-minded causality associated with the gene-centered view and so it must recover to the spirit of Aristotelian natural history and its four types of causation in order to foster the evo-devo field of research. (shrink)

This note discusses the importance of Natural History (biology) in the development of Aristotle philosophy and scientific outlook, and so the importance of considering Aristotle's philosophy as a necessary and useful background for contemporary biology.

There have been several attempts to identify what Aristotle holds as distinctive to magnificence. The most common interpretation is that magnificence is generosity of large wealth. Irwin proposes an alternative where magnificence is generosity applied to complicated common-good projects while Curzer’s alternative is that magnificence is heroic generosity. My position is that these three positions misinterpret Aristotle’s magnificence by explicitly or implicitly rejecting some of the claims that Aristotle makes.

Chance and necessity are mainstays of explanation in current biology, dominated by the neo-Darwinian outlook, a blend of the theory of evolution by natural selection with the basic tenets of population genetics. In such a framework the form of living organisms is somehow a side effect of highly contingent, historical accidents. Thus, at a difference of other sciences, biology apparently lacks theoretical principles that in a law-like fashion may explain the emergence and persistence of the characteristic forms of living organisms (...) that paradoxically, given the current importance attributed to chance, can be grouped into organized structural typologies. Nevertheless, the present essay shows that since its origins in Aristotelian natural history, biology aimed at achieving rational, non-accidental, explanations for the wide variety of living forms endowed with characteristic behaviors that constitute the landscape of biological species. (shrink)

This book deals with embryology although it is not a book on embryology. It is in itself like a developing embryo and at a difference of textbooks it does not pretend to be an introduction to any particular scientific discipline. This work was born from a fascination about forms and it is the draft of a morphological process: the account of a form coming into being, the form of an as yet unnamed but emerging science. A new science of qualities (...) in which the natural phenomena are understood as wholes, as complex entities, possessing integral properties that are non-reducible to discrete or quantifiable magnitudes. This book is like a jump into the future of science but also it is a return in time in order to find the founder of science. The first thinker that blended speculative thought with the direct observation of facts. This book is a return to the organism, to purpose and meaning, a return to Aristotle. (shrink)

Since Aristotle the central question in biology was the origin of organic form; a question put in the backyard by neo-Darwinism that considers organic form as a side effect of the interactions between genes and their products. On the other hand, the fashionable notion of self-organization also fails to provide a true causal explanation for organic form. For Aristotle form is both a cause and the principle of intelligibility and this coupled to the classical concepts of potentiality and (...) actuality provides a rational framework,currently embodied in the contemporary concept of ‘attractor’, for understanding the origin of organic form. (shrink)

The purpose of this paper is to present a critique of the current view that reduces cancer to a cellular problem caused by specific gene mutations and to propose, instead, that such a problem might become more intelligible, if it is understood as a phenomenon that results from the breakdown of the morphological plan or Gestalt of the organism. Such and organism, in Aristotelian terms, is characterized for presenting a specific morphe or logos (form) and for having a telos (end) (...) to fulfill. A malignant tumor represents an entity separated from both the organic logos and the organic telos. According to the basic postulates of Semiophysics – a blend of Aristotelian physics and Catastrophe Theory developed by René Thom – an organism is a source (original) form individuated by a dominant pregnance that corresponds to its morphogenetic field. Here it is suggested that cancer in aged individuals might result from the progressive exhaustion of developmental constraints that regulate the process of ontogeny, that it is expected to go from the fertilized non-differentiated zygote to the mature fully developed organism, because there is no further point ahead in the developmental pathway past the reproductive age. Cancer in young individuals (before their reproductive maturity) may then be consequence of the premature derangement of such fundamental developmental constraints. In all cases the result is the loss of morphological coherence within the organism. Thus representing a conflict between an organized morphology (the organism) and a part of such a morphology that drifts towards an amorphous state (the tumor). (shrink)

Molecular biology is a relatively new and very successful branch of science but currently it faces challenges posed by very complex issues that cannot be addressed by a traditional reductionist approach. However, despite its origins in the providential shift of some theoretical physicists to biology, currently molecular biology is immersed in a blind trend in which high-throughput technology, able to generate trillions of data, is becoming the leading edge of a discipline that has traded rational and critical thinking for computer (...) power, data crunching and statistics in hope of finding, once more, its way. However, the complex questions facing MB may only be solved by a paradigm shift in the causal way of thinking, so that complex, emergent, non-linear phenomena may be effectively understood in top-down and not in bottom-up terms. (shrink)

Two hundred years after Darwin’s birth, the evolution of living systems is an accepted fact but there is scope for controversy on the mechanisms involved in such a process. Mainstream neo-Darwinism champions the role of natural selection (NS) as the fundamental cause of the evolutionary process as well as of random, contingent events at the genetic level as the main source of variation upon which NS performs its causal role. Thus, according to neo-Darwinism the course of biological evolution is quite (...) unpredictable and the past can only be partially reconstructed by means of a historical narrative.This second-class status for biology within the natural sciences as a merely descriptive, historical science results from the chronic neglect of biological form in the neo-Darwinian discourse. Hereunder I discuss the need for reintroducing form as the central object of biology, aiming at the identification of the general and fundamental principles of biological form. Such a formal biology may go beyond simple historical description achieving a complete, rational explanation of how previous and current morphologies corresponding to identifiable species were established, and so providing a rational foundation for predicting the possible outcomes of future biological evolution on earth and perhaps elsewhere in the universe. (shrink)

For some the gene-centered reductionism that permeates contemporary neo-Darwinism is an obstacle for finding a common explanatory framework for both biological and cultural evolution. Thus social scientists are tempted to find new concepts that might bridge the divide between biology and sociology. Yet since Aristotle we know that the level of explanation must be commensurate with the particular question to be answered. In modern natural science there are many instances where a reductionist approach has failed to provide the right (...) answer to the corresponding question. Thus social scientists risk becoming non-relevant when mimicking some features of the natural sciences (such as hard or soft reductionism) just for the sake of it, instead of finding autonomous explanations commensurate with the level of phenomena studied by social science. (shrink)

Il n'est pas une branche du savoir de son temps qu'Aristote n'ait étudiée : de la logique à la rhétorique en passant par la dialectique, de la physique et la chimie à la cosmologie, de la métaphysique et la théologie aux mathématiques, de la politique et l'éthique à la psychologie, sans oublier le très important corpus biologique et le recueil des différentes constitutions qu'il avait compilées avec ses élèves. On redécouvre aujourd'hui l'importance du "maître de ceux qui savent" tant pour (...) l'Occident chrétien que pour l'Orient islamique, et l'on trouve un fondement aristotélicien à presque toutes nos sciences dites "humaines". Cette édition comprend la totalité des oeuvres authentiques d'Aristote, ainsi que la traduction inédite en français des Fragments. Elle comporte en outre une introduction générale, des notices de présentation pour chaque groupe de traités, un index des notions et un index des philosophes, qui permettent à tous, néophytes ou familiers, de redécouvrir Aristote. (shrink)

This work has been selected by scholars as being culturally important and is part of the knowledge base of civilization as we know it. This work is in the public domain in the United States of America, and possibly other nations. Within the United States, you may freely copy and distribute this work, as no entity has a copyright on the body of the work. Scholars believe, and we concur, that this work is important enough to be preserved, reproduced, and (...) made generally available to the public. To ensure a quality reading experience, this work has been proofread and republished using a format that seamlessly blends the original graphical elements with text in an easy-to-read typeface. We appreciate your support of the preservation process, and thank you for being an important part of keeping this knowledge alive and relevant. (shrink)

Sartre fits fully within the phenomenological tradition inaugurated by Husserl, although he somewhat reelaborates it in an original way, on the basis of Heidegger’s philosophy, with the aim of outlining, in a first stage of his thoughts dating back to the publication of Being and Nothingness, the features stemming from his peculiar atheistic existentialism. Subsequently, in the mature stage of his intellectual itinerary, Sartre will attempt to combine the existentialist ideas with the basic principles of Marxism, a synthesis that will (...) create important works such as Search for a Method and Critique of Dialectical Reason. This chapter analyses time from the phenomenological perspective of the Sartrean ontology of temporality. This analysis allows to conceive the typically human “existential time” as a permanent existence out of oneself. For this purpose, we will retrace the fundamentals of Sartre’s phenomenological ontology outlined in his most important work of 1943, Being and Nothingness, focusing in particular on the structures of consciousness understood as “être-pour-soi”, i.e. the conditions of man’s “absolute freedom”, which Sartre refers to when he shows the one “pour-soi” as the being who is pure nothingness. (shrink)

Arthur Madigan presents a clear, accurate new translation of the third book of Aristotle's Metaphysics, together with two related chapters from the eleventh book. Madigan's accompanying introduction and commentary give detailed guidance to these texts, in which Aristotle sets out what he takes to be the main problems of metaphysics or 'first philosophy' and assesses possible solutions to them; he takes his starting-point from the work of earlier philosophers, especially Plato and some of the Presocratics. These texts serve (...) as a useful introduction both to Aristotle's own work on metaphysics and to classical metaphysics in general; they are also a good example of Aristotle's dialectical method, which reasons not from known truths but from reputable opinions. (shrink)

Aristotle was the first philosopher in the Western tradition to address politics systematically and empirically, and he remains a central figure in political theory. This essential volume presents Aristotle's complete political writings—including his Politics, Economics, and Constitution of Athens—in their most authoritative translations, taken from the complete works that is universally recognized as the standard English edition. Edited by Jonathan Barnes, one of the world’s leading scholars of ancient philosophy, and with an illuminating introduction by Melissa Lane, an (...) authority on ancient political philosophy, this compact but comprehensive volume will be invaluable for all students of politics, philosophy, classics, or Western thought. (shrink)

A compilation of lectures by the liberal thinker Armando P. Ribas, which reflect the political philosophy in his historical, ethical, political and economic analysis. Dr. Ribas exposes the correct axiological order, thus demonstrating that the economy is merely consequential and dependent on ethics, politics, and the legal system derived from them.

In the evolution of criminally relevant action in modern crime theory, social action has assumed a particular significance as a dogmatic element that enables the effective protection of legal assets in a society beset by risks. In the vast array of theories regarding the role of the guarantor and its legal and doctrinal development, as well as the jurisprudential extension of equivalence clauses of improper omissions that serve as amplifier devices of the criminal statue through an indirect adaptation, there is (...) a need to identify the most effective means to shield legal assets, which allows for an imputation of passive conducts, despite having an active typical description. This introduces the controversial figure of the improper omission, which is used with the function of perfecting all of the structural elements of the criminal conduct. When an individual knows he is in a position of guarantor and is aware of the potential consequences, but fails to take action, having the means to prevent a foreseeable outcome, this device serves to enhance the criminal protection of legal assets, fostering social solidarity as the basis of the criminal justice system. This system, by satisfying the function of general prevention of the punishment, ideally dissuades the individual from committing crimes with the threat of penalty. These theories are fundamental to understanding criminal responsibility by improper omission in the context of the objective imputation theory. By guiding the evolution and delimitation of its application, they serve as a significant factor in criminal social control in Colombia. (shrink)

Phillips & Silverstein (P&S, 2003) propose that NMDA-receptor dysfunction may be the fundamental neurobiological mechanism underlying and associating impaired holistic perception and cognitive coordination with schizophrenic psychopathology. We discuss how the P&S hypothesis shares different aspects of the weak central coherence account of autism from both theoretical and experimental perspectives. Specifically, we believe that neither those persons with autism nor those with schizophrenia integrate visuo-perceptual information efficiently, resulting in incongruous internal representations of their external world. However, although NMDA-hypofunction may be (...) responsible for perceptual impairments in schizophrenia and possibly autism, we suggest that it is highly unlikely that NMDA-hypofunction is specifically responsible for the autistic behavioral symptomology, as described by P&S in their target article. (shrink)