The genome sequencing revolution has revealed that all species possess a large number of unique genes critical for trait variation, adaptation, and evolutionary innovation. One widely used approach to identify such genes consists of detecting protein‐coding sequences with no homology in other genomes, termed orphan genes. These genes have been extensively studied, under the assumption that they represent valid proxies for species‐specific genes. Here, we critically evaluate taxonomic, phylogenetic, and sequence evolution evidence showing that orphan genes belong to a range (...) of evolutionary ages and thus cannot be assigned to a single lineage. Furthermore, we show that the processes generating orphan genes are substantially more diverse than generally thought and include horizontal gene transfer, transposable element domestication, and overprinting. Thus, orphan genes represent a heterogeneous collection of genes rather than a single biological entity, making them unsuitable as a subject for meaningful investigation of gene evolution and phenotypic innovation. (shrink)

LLMs are statistical models of language learning through stochastic gradient descent with a next token prediction objective. Prompting a popular view among AI modelers: LLMs are just next token predictors. While LLMs are engineered using next token prediction, and trained based on their success at this task, our view is that a reduction to just next token predictor sells LLMs short. Moreover, there are important explanations of LLM behavior and capabilities that are lost when we engage in this kind of (...) reduction. In order to draw this out, we will make an analogy with a once prominent research program in biology explaining evolution and development from the genes eye view. (shrink)

Several decades of work in both philosophy and psychology acutely highlights our limitations as individual inquirers. One way to recognize these limitations is to defer to experts: roughly, to form one’s beliefs on the basis of expert testimony. Yet, as has become salient in the age of Brexit, Trumpist politics, and climate change denial, people are often mistrustful of experts, and unwilling to defer to them. It’s a trope of highbrow public discourse that this unwillingness is a serious pathology. But (...) to what extent is this trope accurate? Answering this requires us to settle both a normative question—under exactly what conditions ought we to defer to experts?—and an empirical question—under what conditions are people willing to defer to experts? The first question has been investigated primarily by philosophers; the second, primarily by psychologists. Yet there is little work integrating these literatures and putting together their results. The aim of this review article is to begin this task, enabling us to begin reaching conclusions about how much real practices of deference diverge from the ideal. We present an opinionated guide to relevant work from both philosophy and psychology, and note places where the literature has important gaps. (shrink)

Some pejoratives are slurs—they target people on the basis of protected characteristics. Other pejoratives are what we can call “cognitive-behavioural pejoratives”: they target contemptible conduct or character, not protected characteristics. These two classes of pejoratives are semantically similar, yet the ethical profiles of their use are radically different. There is an Estonian pejorative that targets people on the basis of a mixture of ethnicity (approximately: Russian) and a cognitive-behavioural trait (approximately: chauvinism). What is the ethical status of the use of (...) such a word: a word that combines properties of ethically very different pejoratives? This paper draws upon interviews with members of the ethnic group that the word’s usage is associated with, and members of the ethnic group targeted by the word, to better understand the laudability and criticizability of various some uses of the pejorative. We defend the view that the pejorative had some plausibly laudable uses during the period when Estonia was annexed by Soviet Russia, and that (even these) uses of the pejorative are in principle susceptible to faults that, when they arise, make use of the word criticizable. (shrink)

Recent claims that artificial intelligence (AI) systems demonstrate “emergent abilities” have fueled excitement but also fear grounded in the prospect that such systems may enable a wider range of parties to make unprecedented advances in areas that include the development of chemical or biological weapons. Ambiguity surrounding the term “emergent abilities” has added avoidable uncertainty to a topic that has the potential to destabilize the strategic landscape, including the perception of key parties about the viability of nonproliferation efforts. To avert (...) these problems in the future, scientists, developers, policymakers, and other parties should take credible steps to strengthen the health of the scientific ecosystem around AI. (shrink)

When you hear music, you experience a repeating pulse that you naturally tap along to—you feel a beat. But you can feel a beat differently under sounds you hear as otherwise alike. Heard each way, things sound different. But, heard each way, nothing seems to change. So why do things sound different? I argue that, surprisingly, the usual theories of perception have no good answer. I then develop a view on which different ways of feeling a beat are different ways (...) of perceiving the same mind-independent features of things. On this view, feeling a beat is hearing sounds as organized within periods of time. And just as we can represent the same events using different calendars, we can perceive the same events using different beats. (shrink)

Robotic warfare has now become a real prospect. One issue that has generated heated debate concerns the development of ‘Killer Robots’. These are weapons that, once programmed, are capable of finding and engaging a target without supervision by a human operator. From a conceptual perspective, the debate on Killer Robots has been rather confused, not least because it is unclear how central elements of these weapons can be defined. Offering a precise take on the relevant conceptual issues, the article contends (...) that Killer Robots are best seen as executors of targeting decisions made by their human programmers. However, from a normative perspective, the execution of targeting decisions by Killer Robots should worry us. The article argues that what is morally bad about Killer Robots is that they replace human agency in warfare with artificial agency, a development which should be resisted. Finally, the article contends that the issue of agency points to a wider problem in just war theory, namely the role of moral rights in our normative reasoning on armed conflict. (shrink)

This paper defends two claims. First, I argue that you always have some reason to comply with the social norms applicable to your situation, no matter how immoral or ridiculous, provided you are in the social domain. This is not a baroque, technical fact about social norms: it is fundamental to understanding what they are, how they work, and how they can be a source of grave injustice. Second, I argue that this fact about social normativity requires re-thinking the distinction (...) between formal and robust normativity. Social norms are not robustly normative. But nor are they merely formally normative. Since these two categories are widely assumed to be exhaustive, this requires revising our normative taxonomy. (shrink)

The view that moods are dispositions has recently fallen into disrepute. In this paper, we want to revitalise it by providing a new argument for it and by disarming an important objection against it. A shared assumption of our competitors (intentionalists about moods) is that moods are ‘diffuse’. First, we will provide reasons for thinking that existing intentionalist views do not in fact capture this distinctive feature of moods that distinguishes them from emotions. Second, we offer a dispositionalist alternative that (...) we think does better. Finally, we disarm the objection that is responsible for dispositionalism’s bad press. (shrink)

Contemporary process metaphysics has achieved a number of important results, most significantly in accounting for emergence, a problem on which substance metaphysics has foundered since Plato. It also faces trenchant problems of its own, among them the related problems of boundaries and individuation. Historically, the quest for ontology may thus have been largely responsible for the persistence of substance metaphysics. But as Plato was well aware, an ontology of substantial things raises serious, perhaps insurmountable problems for any account of our (...) epistemic access to such things. Physical things are subject to change, and as such, they are poor objects of knowledge—if knowledge is to be more reliable than mere opinion. There is a reading of Plato’s Theaetetus on which knowledge may be understood as a relation between an epistemic subject and a logos, where logoi are intrinsically dialectical, and where dialectic is a kind of intersubjective activity. Insofar as this epistemology may be attributed to Plato, the project of this paper is Platonic in spirit. It is also, in a sense, Kantian, in that it divorces ontology from the search for things-in-themselves, redirecting our attention from things to objects: epistemic objects. Such objects can be understood, as Maurice Merleau-Ponty proposed, as shared by multiple subjects by virtue of their participation in an intersubjective world, constituted by what Shaun Gallagher calls participatory sense-making. On an epistemology constructed in this way, the fact that both epistemic objects and their subject are mutable is no obstacle to knowledge. Far-from-equilibrium systems are forever mutable; at thermodynamic equilibrium, there would be neither subject, nor object. Epistemic objects, on this picture, are metastable loci of interactive potential. (shrink)

The ‘explanation paradox’ due to Reiss can be resolved by recognizing that economic models that begin with assumptions of rational choice compel explanatory assent because they exploit a pattern of reasoning humans are hardwired to accept as explanatory: what cognitive scientists call the theory of mind. I review recent research in evolutionary anthropology, neuroscience and developmental psychology that substantiates the conclusion that explanations exploiting expectations and preferences (i.e. beliefs and desires) were hard wired into Hominins as the solution to a (...) design problem in early human evolution, and continue to drive our explanatory and predictive expectations even well beyond their domain of effective employment. Economic models employ this explanatory strategy outside the domain of the effective employment of rational choice models. This is the source of our conviction that they explain in spite of their failure to satisfy any reasonable criteria for scientific explanation. (shrink)

According to Kant, both finite (human) and non‐finite (divine) wills are subject to the moral law, though the manner of their subjection differs. The fact that the law expresses an ‘ought’ for the human will is a function of our imperfection. On this picture, a non‐finite will thus enjoys a certain explanatory priority vis‐à‐vis its finite counterpart: we can understand the practical constraint that binds the latter by seeing how contingent limitations differentiate it from the former. However, a reading of (...) Kant's principle of autonomy that inextricably ties the achievement of willing to the adoption of a practical standpoint, gives us reasons for doubting this order of explanation. It suggests instead that we might best understand the practical ‘ought’ by taking the human will as explanatorily primitive. And if we do so, we can question the coherence of taking a will for which the law is not normative to furnish a paradigmatic exemplification of the relation that lies at the heart of Kant's notion of autonomy: namely, the relation between free volition and moral necessity. (shrink)

Innovation is disruptive and a deeply social phenomenon. As a result, discussions of innovation in the Anglo-American philosophical tradition are often tightly bound up with concerns about individual freedom and pluralism, including pluralism about ethical values. In response, stakeholders looking to evaluate and assess ethical aspects of the innovation ecosystem are often driven to pragmatic approaches that utilize a set of ethical values that can be regarded as “free-standing,” or “thin” in the sense that they are not tied to any (...) particular, substantive conception of the good. This set often includes values such as beneficence, nonmaleficence, respect for autonomy, fairness, and justice. Discussions focused on justice, however, are the least extensive and least well-developed. As a result, most approaches are well-suited to surfacing first-order or direct effects of the discrete activities of a relatively narrow set of stakeholders. Paradoxically, however, such analyses are often not well-suited to identifying and evaluating (a) quintessentially social or higher-order effects (such as network-level or institutional level effects), (b) the role of a larger number of stakeholders who shape the innovation ecosystem in more indirect ways, and (c) some of the positive ethical claims of individuals that are relevant to evaluating innovation. After articulating these shortcomings, I argue that they might be overcome by adopting a justice-led framework for evaluating innovation. (shrink)

The Problem of Suffering (PoS) claims that there is a tension between the existence of a perfect God and suffering. The Problem of Hell (PoH) is a version of PoS which claims that a perfect God would lack morally sufficient reasons to allow individuals to be eternally damned to Hell. A few traditional solutions have been developed to PoH, but each of them is problematic. As such, if there is a solu­tion to PoH that is resistant to these problems, then (...) it deserves our attention. In this paper, I develop precisely such a solution. I call this the Unpopulated Hell View (UHV), which claims that Hell exists as a place where eternal damnation could take place, although it never does. First, I explain how UHV solves PoH. Next, I develop four objections against UHV and defend UHV against them. I argue that, although some of these objections do more damage to UHV than others, UHV has satisfying responses to all of them. Ultimately, I conclude that UHV merits consideration as a novel solution to PoH because it is less problematic than the traditional ones. (shrink)

Augustine scholarship on grief has mostly focused on Confessiones 4 and 9 and De ciuitate dei 14.9, with a focus on how Augustine legitimates Christian expressions of grief. In this essay, I explore the ways in which his account of grief is inflected Christologically, with a primary focus on In Iohannis euangelium tractatus 49, 52, and 60, where Augustine reflects on a set of Johannine texts that speak of Jesus being “troubled”: John 11:33, 12:27, and 13:21. The homiletic context adds (...) to the traditional picture of grief in Augustine scholarship by drawing more attention to issues of Christology. In particular, the Johannine passages afford Augustine the opportunity to highlight the ways in which conceptions of divine power (potestas) shape an interpretation of the difference between Christ’s unique experience of grief in comparison with ours. Christ’s grief, Augustine emphasizes, is only ever voluntary, whereas we experience it involuntarily, and yet it is precisely this difference that prompts Augustine to focus his hearer’s attention on how Christ’s grief serves as the healing of our griefs. (shrink)

It is commonly supposed that at least some states possess a moral right against external intervention in their domestic affairs and all human rights violations give members of the international community reasons to undertake preventive or remedial action against offending states. No state, however, currently protects or could reasonably be expected to protect its subjects’ human rights to a perfect degree. In view of this reality, many have found it difficult to explain how any existing or readily foreseeable state could (...) enjoy a moral right of nonintervention without denying the normative force of human rights. This article seeks to reconcile these apparently incompatible commitments by arguing that, in addition to acting in defense of human rights, outsiders must be appropriately responsive to individuals’ distinct and potentially countervailing interests in collective self-determination. I show that, under certain demanding but not unrealistic conditions, individuals’ interests in self-determination are of sufficient weight not simply to ground a judgment against intervention in particular cases but to generate arobust right of nonintervention on the part of some states that nevertheless fail to secure perfect protection of their subjects’ human rights. (shrink)

Recent claims that artificial intelligence (AI) systems demonstrate “emergent abilities” have fueled excitement but also fear grounded in the prospect that such systems may enable a wider range of parties to make unprecedented advances in areas that include the development of chemical or biological weapons. Ambiguity surrounding the term “emergent abilities” has added avoidable uncertainty to a topic that has the potential to destabilize the strategic landscape, including the perception of key parties about the viability of nonproliferation efforts. To avert (...) these problems in the future, scientists, developers, policymakers, and other parties should take cred- ible steps to strengthen the health of the scientific ecosystem around AI. (shrink)

Hesiod begins his Theogony by telling his audience of rural shepherds and farmers about his encounter with the Muses on Mount Helikon. To assure them he's telling the truth, he claims the humble shepherd's staff of olive wood that he holds before them is in fact a gift from these same goddesses. An apparently mundane artifact is somehow supposed to attest to the divine source of the tales he is about to tell of events not even the Muses themselves could (...) have witnessed, to say nothing of mortal men. Hesiod's overture to his audience has echoes elsewhere in his poetry, as when he claims that a massive stone, visible to all, is the very one Kronos is said to have emitted long ago, after having unwittingly swallowed it... Read More. (shrink)

Nineteenth and twentieth century philosophies of science have consistently failed to identify any rational basis for the compelling character of scientific analogies. This failure is particularly worrisome in light of the fact that the development and diffusion of certain scientific analogies, e.g. Darwin’s analogy between domestic breeds and naturally occurring species, constitute paradigm cases of good science. It is argued that the interactivist model, through the notion of a partition epistemology, provides a way to understand the persuasive character of compelling (...) scientific analogies without consigning them to an irrational or arational context of discovery. (shrink)

This paper expands the definition of gray-marketing to include some ethically problematic marketing activities and techniques used in personal selling in China. Based on this, a conceptual model of gray-marketing for a particular type of selling in which both the sellers and the buyers exhibit problematic ethics in an exchange and the associated hypotheses are developed and tested. The findings show that, first, the respondents have different ethical evaluations of different marketing practices used in personal selling such as giving and (...) accepting gifts, buying and accepting meals, and offering and accepting kickbacks. Some of these practices may not be considered unethical. Second, in terms of ethical assessment, gray-marketing practiced by buying agents is more unacceptable than when practiced by sales agents. Third, a person's ethical evaluation of gray-marketing behavior, empathy for gray-marketing, and belief that gray-marketing has serious consequences, significantly affects his inclination to use gray-marketing. This paper concludes with a discussion of some possible applications of our research findings. (shrink)

Cultural evolutionary theories define prestige as social rank that is freely conferred on individuals possessing superior knowledge or skill, in order to gain opportunities to learn from such individuals. Consequently, information provided by prestigious individuals should be more memorable, and hence more likely to be culturally transmitted, than information from non-prestigious sources, particularly for novel, controversial arguments about which preexisting opinions are absent or weak. It has also been argued that this effect extends beyond the prestigious individual’s relevant domain of (...) expertise. We tested whether the prestige and relevance of the sources of novel, controversial arguments affected the transmission of those arguments, independently of their content. In a four-generation linear transmission chain experiment, British participants recruited online read two conflicting arguments in favour of or against the replacement of textbooks by computer tablets in schools. Each of the two conflicting arguments was associated with one of three sources with different levels of prestige and relevance. Participants recalled the pro-tablets and anti-tablets arguments associated with each source and their recall was then passed to the next participant within their chain. Contrary to our predictions, we did not find a reliable effect of either the prestige or relevance of the sources of information on transmission fidelity. We discuss whether the lack of a reliable effect of prestige on recall might be a consequence of differences between how prestige operates in this experiment and in everyday life. (shrink)

In this period of transition of state monopoly capitalism the working class has become the large majority. Within this majority the proletariat, due to the exchange character of its power, constitutes the care. Beside it new groups of intellectuals are emerging with radical-democratic demands.

This book brings together two of the most powerful and relevant philosophical critiques of human rights: the post-colonialist and the post-Althusserian, its balanced internal structure not just throwing these two critiques together, but actually forcing them to enter into confrontation and dialogue. The book is organised in three parts: at each end, the post-colonialist and the post-Althusserian critiques are represented by some of their main thinkers, while in the middle, an American intermezzo functions as a genuine Derridian supplement: always already (...) contaminating the purity of the two theoretical schools, preventing their enclosure and, hence, fuelling and complicating further their mutual confrontation. As in any authentic dialogue, the introduction and the conclusion each claim victory for one of the sides by changing the very terms and rules of the dialogue, picturing it as a confrontation between emancipatory universalism and inefficient particularism, or as a split between hypocrisy and truth. (shrink)

Perception of (and during) events is a necessary feature of any perceptual theory. Norman's dual-process approach cannot account for the perception of events without substantial interactions between the dorsal and ventral systems. These interactions, as outlined by Norman, are highly problematical. The necessity for interactions between the two systems makes the distinction useless.

Penelope Maddy's original solution to the dilemma posed by Benacerraf in his 'Mathematical Truth' was to reconcile mathematical empiricism with mathematical realism by arguing that we can perceive realistically construed sets. Though her hypothesis has attracted considerable critical attention, much of it, in my view, misses the point. In this paper I vigorously defend Maddy's account against published criticisms, not because I think it is true, but because these criticisms have functioned to obscure a more fundamental issue that is well (...) worth addressing: in general -- and not only in the mathematical domain -- empiricism and realism simply cannot be reconciled by means of an account of perception anything like Maddy's. But because Maddy's account of perception is so plausible, this conclusion raises the specter of the broader incompatibility of realism and empiricism, which contemporary philosophers are frequently at pains to forget. (shrink)

This article discusses Kracauer’s analysis of mass ornament in light of Deleuze’s concept of ritournelle. Kracauer was interested in the spectacle of Tiller Girls and found the principle of the capitalist production process in its ornamental formations. Capitalism destroys any natural organisms for its means and excludes any resistance from its effective procedure. This operation necessarily comes along with calculation and mechanisation. All individuals have scaled up statistics charts and scrambled with machines completely. People have turned into masses who are (...) no longer different in form but simple technical objects that can be equally employed at any point of the globe. Kracauer understood mass ornament as the surface-level expression of global capitalism, which revealed its unconscious. He emphasised the ambivalence of mass ornament and a possible line of escape from capitalist rationality through the emptiness of its formal excess. Deleuze’s concept of ritournelle may shed light on a similar question of mass ornament and push its scope beyond Kracauer’s analysis. The two philosophers seem to share the frame of formalism when they deploy their arguments concerning form and depth; however, Deleuze put forward the issue of temporality in his discussion of ritournelle, a crucial question that Kracauer omits. (shrink)

Resumen: Durante la década del sesenta, la revista Movie hereda de Cahiers du cinéma las preferencias por la politique des auteurs y por cierto cine norteamericano. No obstante, sin abandonar esa predilección por un “cine de directores”, a lo largo de su trayectoria la revista británica intentará desarrollar un riguroso método de análisis formal a través de detallados close readings de los films. Algunos de sus integrantes buscan aplicar al cine los planteos de F. R. Leavis y la revista Scrutiny (...) a propósito de la crítica literaria. Es esta modulación analítica la que será puesta en cuestión con el auge del estructuralismo y el posestructurailsmo a los que se asocia la revista Screen en los años 70.: During the sixties, the journal Movie inherits from Cahiers du cinéma the preferencies for a politique des auteurs and for certain american films. However, never abandoning this tendency towards a “cinema of directors”, the british journal develops a rigorous method of formal analysis and detailed close readings. Some of its members try to apply to cinema the concepts elaborated by F. R. Leavis and the journal Scrutiny in reference to literary criticism. It is precisely this analytic method that will be questioned during the boom of structuralism and post structuralism to which the journal Screen will be asociated in the 70s. (shrink)

Contingencies of the early nuclear arms race Content Type Journal Article Pages 1-23 DOI 10.1007/s11016-010-9495-z Authors S. S. Schweber, Department of the History of Science, Harvard University, Science Center 371, Cambridge, MA 02138, USA Alex Wellerstein, Department of the History of Science, Harvard University, Science Center 371, Cambridge, MA 02138, USA Ethan Pollock, Department of History, Box N, Brown University, Providence, RI 02912, USA Barton J. Bernstein, History Department, Building 200, Stanford University, Stanford, CA 94305-2024, USA Michael D. Gordin, (...) History Department, 305 Dickinson Hall, Princeton University, Princeton, NJ 08544, USA Journal Metascience Online ISSN 1467-9981 Print ISSN 0815-0796. (shrink)

Alex Blum ABSTRACT: We show that Kripke’s argument for the necessity of identity statements relating objects a and b by their rigid designators demands an additional significant premise. Download PDF.

Alex Blum ABSTRACT: We argue that the part of the future which is up to us is in principle unknowable. Download PDF.

Hastings Center Report, Volume 51, Issue 5, Page 30-41, September‐October 2021.

The present volume, comprising ninteen articles by renowned scholars, is divided into three sections, namely, Buddhist Jaina and Hindu Philsosphical Researches.

Alex Oliver and Timothy Smiley provide a new account of plural logic. They argue that there is such a thing as genuinely plural denotation in logic, and expound a framework of ideas that includes the distinction between distributive and collective predicates, the theory of plural descriptions, multivalued functions, and lists.

Origens : Alex Atala, Fernando e Humberto Campana -- Presente : Fernando e Humberto Campana e Jum Nakao -- Intermezzo : convívio : Jam Nakao e colaboradores -- Destinos : Alex Atala e Jum Nakao -- Entrevistas -- Um pouco de história.

In Individuality and Mass Democracy, Alex Zarakas acknowledges the importance of both, but focuses on the responsibility of citizens.

Alex Oliver and Timothy Smiley provide a new account of plural logic. They argue that there is such a thing as genuinely plural denotation in logic, and expound a framework of ideas that includes the distinction between distributive and collective predicates, the theory of plural descriptions, multivalued functions, and lists.

In this paper, we consider how certain longstanding philosophical questions about mental representation may be answered on the assumption that cognitive and perceptual systems implement hierarchical generative models, such as those discussed within the prediction error minimization framework. We build on existing treatments of representation via structural resemblance, such as those in Gładziejewski :559–582, 2016) and Gładziejewski and Miłkowski, to argue for a representationalist interpretation of the PEM framework. We further motivate the proposed approach to content by arguing that it (...) is consistent with approaches implicit in theories of unsupervised learning in neural networks. In the course of this discussion, we argue that the structural representation proposal, properly understood, has more in common with functional-role than with causal/informational or teleosemantic theories. In the remainder of the paper, we describe the PEM framework for approximate Bayesian inference in some detail, and discuss how structural representations might arise within the proposed Bayesian hierarchies. After explicating the notion of variational inference, we define a subjectively accessible measure of misrepresentation for hierarchical Bayesian networks by appeal to the Kullbach–Leibler divergence between posterior generative and approximate recognition densities, and discuss a related measure of objective misrepresentation in terms of correspondence with the facts. (shrink)

Volume 20, Issue 7, July 2020, Page W7-W11.

What is it to want something? Or, as philosophers might ask, what is a desire? This book defends “desire-as-belief”, the view that desires are just a special subset of our beliefs: normative beliefs. This view entitles us to accept orthodox models of human motivation and rationality that explain those things with reference to desire, but nonetheless to also make room for our normative beliefs to play a role in those domains. And this view tells us to diverge from the orthodox (...) view on which desires themselves can never be right or wrong. Rather, according to desire-as-belief, our desires can themselves be assessed for their accuracy, and they are wrong when they misrepresent normative features of the world. Hume says that it is not contrary to reason to prefer the destruction of the whole world to the scratching of your finger, but he is wrong: it is foolish to prefer the destruction of the whole world to the scratching of your finger, and this is foolish because this preference misrepresents the relative worth of these things. (shrink)