BackgroundWinning funding for health and medical research usually involves a lengthy application process. With success rates under 20%, much of the time spent by 80% of applicants could have been better used on actual research. An alternative funding system that could save time is using democracy to award the most deserving researchers based on votes from the research community. We aimed to pilot how such a system could work and examine some potential biases.MethodsWe used an online survey with a convenience (...) sample of Australian researchers. Researchers were asked to name the 10 scientists currently working in Australia that they thought most deserved funding for future research. For comparison, we used recent winners from large national fellowship schemes that used traditional peer review.ResultsVoting took a median of 5 min (inter-quartile range 3 to 10 min). Extrapolating to a national voting scheme, we estimate 599 working days of voting time (95% CI 490 to 728), compared with 827 working days for the current peer review system for fellowships. The gender ratio in the votes was a more equal 45:55 (female to male) compared with 34:66 in recent fellowship winners, although this could be explained by Simpson’s paradox. Voters were biased towards their own institution, with an additional 1.6 votes per ballot (inter-quartile range 0.8 to 2.2) above the expected number. Respondents raised many concerns about the idea of using democracy to fund research, including vote rigging, lobbying and it becoming a popularity contest.ConclusionsThis is a preliminary study of using voting that does not investigate many of the concerns about how a voting system would work. We were able to show that voting would take less time than traditional peer review and would spread the workload over many more reviewers. Further studies of alternative funding systems are needed as well as a wide discussion with the research community about potential changes. (shrink)

Inspired by the writings of J. M. Hinton (1967a, 1967b, 1973), but ushered into the mainstream by Paul Snowdon (1980–1, 1990–1), John McDowell (1982, 1986), and M. G. F. Martin (2002, 2004, 2006), disjunctivism is currently discussed, advocated, and opposed in the philosophy of perception, the theory of knowledge, the theory of practical reason, and the philosophy of action. But what is disjunctivism?

Geologists, Paleontologists and other historical scientists are frequently concerned with narrative explanations targeting single cases. I show that two distinct explanatory strategies are employed in narratives, simple and complex. A simple narrative has minimal causal detail and is embedded in a regularity, whereas a complex narrative is more detailed and not embedded. The distinction is illustrated through two case studies: the ‘snowball earth’ explanation of Neoproterozoic glaciation and recent attempts to explain gigantism in Sauropods. This distinction is revelatory of historical (...) science. I argue that at least sometimes which strategy is appropriate is not a pragmatic issue, but turns on the nature of the target. Moreover, the distinction reveals a counterintuitive pattern of progress in some historical explanation: shifting from simple to complex. Sometimes, historical scientists rightly abandon simple, unified explanations in favour of disunified, complex narratives. Finally I compare narrative and mechanistic explanation, arguing that mechanistic approaches are inappropriate for complex narrative explanations. (shrink)

Abstract‘Behavioural modernity’ isn’t what it used to be. Once conceived as an integrated package of traits demarcated by a clear archaeological signal in a specific time and place, it is now disparate, archaeologically equivocal, and temporally and spatially spread. In this paper we trace behavioural modernity’s empirical and theoretical developments over the last three decades, as surprising discoveries in the material record, as well the reappraisal of old evidence, drove increasingly sophisticated demographic, social and cultural models of behavioural modernity. We (...) argue, however, that some approaches to identifying and categorizing modernity have not kept up with this new picture. This is due to what we term ‘Rubicon expectations’: classificatory and interpretive practices which look for or assume clear demarcations in behavioural and cultural processes. We develop a philosophical account of ‘investigative disintegration’ to capture how our understanding of behavioural modernity has changed, and how Rubicon-based practices have become inadequate. Disintegration, in the form we analyse, occurs when scientists’ conception of a phenomenon shifts sufficiently to reshape an investigation’s epistemic structure. For behavioural modernity, the explanatory weight which once lay on identifying ‘switch-points’ in the innate suite of hominin cognitive capacities, lies now in understanding the social and demographic environments that were capable of sustaining and nourishing more complex material cultures. Finally, we argue that the phenomenon itself has not disintegrated to the point that we are left with no interesting explanandum: for all its mosaic, disparate nature, there are still good reasons for behavioural modernity to retain its central place in investigation of our species' origins. (shrink)

The last two decades have seen two significant trends emerging within the philosophy of science: the rapid development and focus on the philosophy of the specialised sciences, and a resurgence of Aristotelian metaphysics, much of which is concerned with the possibility of emergence, as well as the ontological status and indispensability of dispositions and powers in science. Despite these recent trends, few Aristotelian metaphysicians have engaged directly with the philosophy of the specialised sciences. Additionally, the relationship between fundamental Aristotelian concepts—such (...) as "hylomorphism", "substance", and "faculties"—and contemporary science has yet to receive a critical and systematic treatment. _Neo-Aristotelian Perspectives on Contemporary Science _aims to fill this gap in the literature by bringing together essays on the relationship between Aristotelianism and science that cut across interdisciplinary boundaries. The chapters in this volume are divided into two main sections covering the philosophy of physics and the philosophy of the life sciences. Featuring original contributions from distinguished and early-career scholars, this book will be of interest to specialists in analytical metaphysics and the philosophy of science. (shrink)

Our epistemic access to the past is infamously patchy: historical information degrades and disappears and bygone eras are often beyond the reach of repeatable experiments. However, historical scientists have been remarkably successful at uncovering and explaining the past. I argue that part of this success is explained by the exploitation of dependencies between historical events, entities, and processes. For instance, if sauropod dinosaurs were hot blooded, they must have been gluttons; the high-energy demands of endothermy restrict sauropod grazing strategies. Understanding (...) such dependencies extends our reach into the past in spite of incomplete data. In addition, this serves as a counterexample to two accounts of method in the historical sciences. By one, historical science proceeds by identifying ‘smoking guns’: traces that discriminate between live hypotheses. By the other, historical hypotheses are supported by consilience: the convergence of independent lines of evidence. However, testing for ‘coherency’ between past hypotheses also plays a critical role in historical confirmation. Just as historical scientists exploit dependencies between past entities and present entities to infer what the past was like, they also exploit dependencies between past entities themselves. I do not suggest that archetypical historical science proceeds in this manner. Rather, the lesson I draw is that historical methodology cannot be characterized as archetypically relying on one method or another. Historical science is at base opportunistic, and is resistant to unitary analyses. 1 Introduction2 Snowballs and Explosions: The Basic Idea3 Were Sauropods Endothermic?4 Dependent Entities and Interdependent Explanations5 Smoking Guns and Consilience. (shrink)

Paleobiologists often provide simple narratives to explain complex, contingent episodes. These narratives are sometimes ‘one-shot hypotheses’ which are treated as being mutually exclusive with other possible explanations of the target episode, and are thus extended to accommodate as much about the episode as possible. I argue that a provisional preference for such hypotheses provides two kinds of productive scaffolding. First, they generate ‘hypothetical difference-makers’: one-shot hypotheses highlight and isolate empirically tractable dependencies between variables. Second, investigations of hypothetical difference-makers provision explanatory (...) resources, the ‘raw materials’ for constructing more complex—and likely more adequate—explanations. Provisional preferences for simple, one-shot hypotheses in historical science, then, is defeasibly justified on indirect—strategic—grounds. My argument is made in reference to recent developments regarding the K–Pg extinction. (shrink)

In this paper I discuss the so-called problem of creeping minimalism, the problem of distinguishing metaethical expressivism from its rivals once expressivists start accepting minimalist theories about truth, representation, belief, and similar concepts. I argue that Dreier’s ‘explanation’ explanation is almost correct, but by critically examining it we not only get a better solution, but also draw out some interesting results about expressivism and non-representationalist theories of meaning more generally.

Many accounts of scientific modeling conceive of models as fictions: scientists interact with models in ways analogous to various aesthetic objects. Fictionalists follow most other accounts of modeling by taking them to be revelatory of the actual world in virtue of bearing some resemblance relation to a target system. While such fictionalist accounts capture crucial aspects of modelling practice, they are ill-suited to some design and engineering contexts. Here, models sometimes serve to underwrite design projects whereby real-world targets are constructed. (...) In such circumstances, it is unclear what the model is supposed to resemble. Further, while fictionalists often require that models qua models have their content in virtue of construal or interpretation, in some engineering and design contexts success-conditions do not require such content—all that is required is that the model generates the required outputs. I take these points to motivate a view which accommodates fictionalism, but is broader. I articulate and defend an account of models as tools: specifically, material objects which are put to particular uses in particular contexts. (shrink)

activity” has been considered to play a major role in the short-term maintenance of memories. Many studies since then have provided support for this view and greatly advanced our knowledge of the effects of stimulus type and modality on delay activity and its temporal dynamics. In humans, working memory has also been a subject of intense investigation using scalp and intracranial electroencephalography as well as magnetoencephalography, which provide estimates of local population activity. The published findings include reports of systematic changes (...) in signal amplitude during working memory in the theta, alpha, beta. (shrink)

Debate about the epistemic prowess of historical science has focused on local underdetermination problems generated by a lack of historical data; the prevalence of information loss over geological time, and the capacities of scientists to mitigate it. Drawing on Leonelli’s recent distinction between ‘phenomena-time’ and ‘data-time’ I argue that factors like data generation, curation and management significantly complexifies and undermines this: underdetermination is a bad way of framing the challenges historical scientists face. In doing so, I identify circumstances of epistemic (...) scarcity where underdetermination problems are particularly salient, and discuss cases where legacy data—data generated using differing technologies and systems of practice—are drawn upon to overcome underdetermination. This suggests that one source of overcoming underdetermination is our knowledge of science’s past. Further, data-time makes agnostic positions about the epistemic fortunes of scientists working under epistemic scarcity more plausible. But agnosticism seems to leave philosophers without much normative grip. So, I sketch an alternative approach: focusing on the strategies scientists adopt to maximize their epistemic power in light of the resources available to them. (shrink)

. Philosophers and scientists often cite ontic factors when explaining the methods and success of scientific inquiry. That is, the adoption of a method or approach is explained in reference to the kind of system in which the scientist is interested: these are explanations of why scientists do what they do, that appeal to properties of their target systems. We present a framework for understanding such “Opticks to his Principia. Newton’s optical work is largely experiment-driven, while the Principia is primarily (...) mathematical, so usually, each work is taken to exemplify a different kind of science. However, Newton himself often presented them in terms of a largely consistent method. We use our framework to articulate an original and plausible position: that the differences between the Opticks and the Principia are due to the kinds of systems targeted. That is, we provide an ontic-driven explanation of methodological differences. We suspect that ontic factors should have a more prominent role in historical explanations of scientific method and development. (shrink)

Slavoj Žižek is one of the most interesting and important philosophers working today, known chiefly for his theoretical explorations of popular culture and contemporary politics. This book focuses on the generally neglected and often overshadowed philosophical core of Žižek’s work—an essential component in any true appreciation of this unique thinker’s accomplishment. His central concern, Žižek has proclaimed, is to use psychoanalysis to redeploy the insights of late-modern German philosophy, in particular, the thought of Kant, Schelling, and Hegel. By taking this (...) avowal seriously, Adrian Johnston finally clarifies the philosophical project underlying Žižek’s efforts. His book charts the interlinked ontology and theory of subjectivity constructed by Žižek at the intersection of German idealism and Lacanian theory. Johnston also uses Žižek’s combination of philosophy and psychoanalysis to address two perennial philosophical problems: the relationship of mind and body, and the nature of human freedom. By bringing together the past two centuries of European philosophy, psychoanalytic metapsychology, and cutting-edge work in the natural sciences, Johnston develops a transcendental materialist theory of subjectivity—in short, an account of how more-than-material forms of subjectivity can emerge from a corporeal being. His work shows how an engagement with Žižek’s philosophy can produce compelling answers to today’s most vexing and urgent questions as inherited from the history of ideas. (shrink)

Cognitivism about trust says that it requires belief that the trusted is trustworthy; non-cognitivism denies this. At stake is how to make sense of the strong but competing intuitions that trust is an attitude that is evaluable both morally and rationally. In proposing that one's respect for another's agency may ground one's trusting beliefs, second-personal accounts provide a way to endorse both intuitions. They focus attention on the way that, in normal situations, it is the person whom I trust. My (...) task is to develop an account of the latter insight without the controversial theoretical commitments of the former. I propose a functional account for why the second and third-personal ‘systems’ operate not just in parallel, but in tandem, in support of a cognitivist account of trust. (shrink)

PYRRHONIAN BUDDHISM: AN IMAGINATIVE RECONSTRUCTION -/- Author: -/- Adrian Kuzminski 279 Donlon Road Fly Creek, NY 13337 USA -/- Description of Pyrrhonian Buddhism: -/- The ancient Greek sceptic philosopher, Pyrrho of Elis, accompanied Alexander the Great to India, where he had contacts with Indian sages, so-called naked philosophers (gymnosophists), among whom were very probably Buddhist mendicants, or sramanas. My work, entitled Pyrrhonian Buddhism, takes seriously the hypothesis that Pyrrho’s contact with early Buddhists was the occasion of his rethinking, in (...) a Greek philosophical idiom, of what he experienced in those encounters. This has major implications for our understanding of both Buddhism and Pyrrhonism. -/- Pyrrho’s rethinking of Buddhism, I argue, enabled him to introduce into Greek philosophy and culture several key Buddhist notions. These include the primacy and interdependence of immediate phenomenal experience (which the Buddhists called dependent origination), the suspension of judgment about beliefs lacking phenomenal verification (reflecting the scepticism of the Buddha about ‘unanswered’ or ‘metaphysical’ questions), and the promise of personal enlightenment said to follow such suspension, which Pyrrho called ataraxia, and the Buddhists called bodhi. -/- Pyrrho, like Socrates, wrote nothing, but the movement he founded—Pyrrhonism--became an important tradition in Western philosophy. When the texts of later Pyrrhonian philosophers, particularly Sextus Empiricus, were redicovered during the Renaissance, they sparked a reexamination of the foundations of knowledge, thereby helping to prompt the modern scientific revolution. -/- The notion that early Buddhism played a pivotal role in the birth of ancient Greek Pyrrhonian philosophy remains provocative, but has found increasing support in recent years. An earlier work of mine, Pyrrhonism: How the Ancient Greeks Reinvented Buddhism (Lexington Books, 2008), was, as far as I know, the first book-length comparison of the common features of the two traditions. My current work, Pyrrhonian Buddhism, seeks to broaden and deepen this comparison. It argues that ancient Greek Pyrrhonism is best understood as a fully developed but hitherto largely unrecognized Western version of Buddhism. -/- The Introduction reviews our current understanding of Pyrrhonism in light of recent scholarship on ancient Greek-Indian cultural exchanges, and outlines the methodology I employ. -/- Part I of the book offers re-readings of the classic Pyrrhonian texts, with parallels to Buddhism in mind, including Diogenes Laertius (Chapter One), Sextus Empiricus (Chapter Two) and Timon and Aulus Gellius (Chapter Three). -/- Part II enlists the rubric of the Three Turnings of the Wheel of Dharma to illuminate the fundamental points of comparison between early Buddhism and ancient Pyrrhonism. -/- The First Turning (Chapter Four) centers on the Buddhist insistence on the dependent origination of the objects of immediate consciousness, which can also be found in the understanding of immediate experience expressed in the phenomenalistic atomism of the Pyrrhonists. The Second Turning (Chapter Five), as posed by the ‘unanswered questions’ of the Buddha and the ‘emptiness’ of the Madhyamaka, finds its Pyrrhonian correlation in the suspension of judgment over ‘indeterminate’ beliefs. And the Third Turning (Chapter Six), reported as bodhi in Buddhism and ataraxia in Pyrrhonism, is shown in both traditions to follow liberation from suffering and existential angst, caused by what the Buddhists call our attachments and the Pyrrhonists call our beliefs. -/- Other Writers/Commentators: -/- Aspects of the Pyrrhonian/Buddhism question have been addressed by Edward Conze, Everard Flintoff, Thomas McEvilley, Jay Garfield, Mathew Neale, Ethan Mills, Christopher Beckwith, and Robin Brons, among other recent writers. The book-length studies on the issue (since my earlier work) are by Beckwith (Greek Buddha) and Neal (Madhyamaka and Pyrrhonism). Other writers/scholars with relevant expertise include C. W. Huntington, Jr., Charles Goodman, Stephen Batchelor, Dan Lusthaus, Rupert Gethin, and Mark Siderits. -/- . (shrink)

Wie wird Kunst in sozialen Prozessen wirksam? Welche Rolle spielen Stereotypen in der Begegnung? Wie hängen Wahrnehmen und Handeln zusammen? Dieses Buch ist ein Plädoyer für die Bilder im Zeitalter großer sozio-politischer Wandlungen. Arbeiten von Tania Bruguera, Isaac Julien, Nikki S. Lee, Teresa Margolles, Adrian Piper, Santiago Sierra und Lorna Simpson werden als performative Räume erschlossen. In den Bildern kommen andere Menschen sehr nahe und die am Werk Teilhabenden begegnen sich selbst in ihnen. Begehren und Diskriminieren der Anderen (...) werden als essenzielle Bewusstseinsprozesse reflektierbar. Stereotype Repräsentationen kommen in Bewegung. Die Interaktion der äußeren und inneren Bilder löst dialogische Prozesse aus, die Wahrnehmen und Handeln nachhaltig verändern. Thomas R. Huber unternimmt einen methodisch innovativen Brückenschlag zwischen Identitätspolitik, Ethik und Ästhetik und macht so Kunst als sozio-politisches Agens greifbar. (shrink)

This article outlines procedures for the feedback of individual research data to participants. This feedback framework was developed in the context of a personalized medicine research project in Canada. Researchers in this domain have an ethical obligation to return individual research results and/or material incidental findings that are clinically significant, valid and actionable to participants. Communication of individual research data must proceed in an ethical and efficient manner. Feedback involves three procedural steps: assessing the health relevance of a finding, re-identifying (...) the affected participant, and communicating the finding. Re-identification requires researchers to break the code in place to protect participant identities. Coding systems replace personal identifiers with a numerical code. Double coding systems provide added privacy protection by separating research data from personal identifying data with a third "linkage" database. A trusted and independent intermediary, the "keyholder", controls access to this linkage database. (shrink)

Some authors claim that hate speech plays a key role in perpetuating unjust social hierarchy. One prima facie plausible hypothesis about how this occurs is that hate speech has a pernicious influence on the attitudes of children. Here I argue that this hypothesis has an important part to play in the formulation of an especially robust case for general legal prohibitions on hate speech. If our account of the mechanism via which hate speech effects its harms is built around claims (...) about hate speech’s influence on children, then we will be better placed to acquire evidence that demonstrates the processes posited in our account, and better placed to ascribe responsibility for these harms to individuals who engage in hate speech. I briefly suggest some policy implications that come with developing an account of the harm of hate speech along these lines. (shrink)

Should we implement epistemically paternalistic measures outside of the narrow range of cases, like legal trials, in which their benefits and justifiability seem clear-cut? In this chapter I draw on theories of student-led pedagogy, and Jane Friedman’s work on norms of inquiry, to argue against this prospect. The key contention in the chapter is that facts about an inquirer’s interests and temperament have a bearing on whether it is better for her to, at any given moment, pursue epistemic goods via (...) outward-facing evidence-acquisition, or in a more introspective, ratiocinative fashion. This makes problems for any non-consultative approach to assisting people in inquiry, and speaks in favor of approaches which, as with student-led pedagogy, aim to ‘tap into’ the inquirer’s interests and temperament in helping them to learn. (shrink)

ABSTRACT When hope is discussed in bioethics’ literature, it is most often in the context of ‘false hopes’ and/or how to maintain hope while breaking bad news to patients. Little or no time is generally devoted to the description of hope that supports these analyses. In this paper, I present a detailed description of hope, one designed primarily for the healthcare context. Noting that hope is an emotional attitude, four key aspects are explored. In particular, the function of imagination in (...) hope is discussed in depth. Through an examination of the relationship between hope and vulnerability, I demonstrate how adequately describing hope can broaden the normative inquiry into the role of hope in healthcare. Three ways in which persons with hope can be vulnerable are illustrated, and the challenge of how healthcare providers can attend in moral ways to the hopes of patients is identified. (shrink)

The ethical dilemma of large-scale multinational corporations is presented. The list of complaints and issues is summarized. A case is made for the concept of multinationals being inherently beneficial in today's world of high technology and dependence on international trade. The difficulty is extreme power wielded by some groups. It is concluded that a philosophical ideal is for control on size and power as well as international rules to prevent abuses of power. The concern is that today the worthiness of (...) being relatively small is slowly but surely being eroded. (shrink)

This Handbook addresses Chaucer's poetry in the context of several disciplines, including late medieval philosophy and science, Mediterranean culture, comparative European literature, vernacular theology, and popular devotion.

The past can be a stubborn subject: it is complex, heterogeneous and opaque. To understand it, one must decide which aspects of the past to emphasise and which to minimise. Enter frameworks. Frameworks foreground certain aspects of the historical record while backgrounding others. As such, they are both necessary for, and conducive to, good history as well as good philosophy. We examine the role of frameworks in the history and philosophy of science and argue that they are necessary for both (...) forms of enquiry. We then suggest that the right attitude towards frameworks is pluralism rather than monism: there is no single correct framework to be applied to a given scientific episode. Rather, a multitude of different frameworks are more or less appropriate given various contexts and aims. From this perspective, good frameworks generate and further, rather than frustrate, historical and philosophical enquiry. Our view sheds light on historical disagreement, and on the relationship between philosophy and history of science. (shrink)

Despite the growing interest in Aristotelian approaches to contemporary philosophy of science, few metaphysicians have engaged directly with the question of how a neo-Aristotelian metaphysics of nature might change the landscape for theological discussion concerning theology and naturalism, the place of human beings within nature, or the problem of divine causality. The chapters in this volume are collected into three thematic sections: Naturalism and Nature, Mind and Nature, and God and Nature. By pushing the current boundaries of neo-Aristotelian metaphysics to (...) recover the traditional notion of substantial forms in physics, reframe the principle of proportionality in biology, and restore the hierarchy of being familiar to ancient philosophy, this book advances a metaphysically unified framework that accommodates both scientific and theological knowledge, enriching the interaction between science, philosophy and theology. Neo-Aristotelian Metaphysics and the Theology of Nature will be of interest to scholars and advanced students working in metaphysics, philosophy of science, natural theology, philosophical theology, and analytic theology. (shrink)

Some logical properties of modal languages in which actuality is expressible are investigated. It is argued that, if a sentence like 'Actually, Quine is a distinguished philosopher' is understood as a special case of world-indexed sentences (the index being the actual world), then actuality can be expressed only under strong modal assumptions. Some rival rigid and indexical approaches to actuality are discussed.

(2002). Sartre on Friendship: Promoting Difference while Preserving Commitment. Journal of the British Society for Phenomenology: Vol. 33, The Human Condition, Others, and Writing, pp. 260-272.

The information contained within the linear sequence of bases (the genome) must be faithfully replicated in each cell cycle, with a balance of constancy and variation taking place over the course of evolution. Recently, it has become clear that additional information important for genetic regulation is contained within the chromatin proteins associated with DNA (the epigenome). Epigenetic information also must be faithfully duplicated in each cell cycle, with a balance of constancy and variation taking place during the course of development (...) to achieve differentiation while maintaining identity within cell lineages. Both the genome and the epigenome are synthesized at the replication fork, so the events occurring during S‐phase provide a critical window of opportunity for eliciting change or maintaining existing genetic states. Cells discriminate between different states of chromatin through the activities of proteins that selectively modify the structure of chromatin. Several recent studies report the localization of certain chromatin modifying proteins to replication forks at specific times during S‐phase. Since transcriptionally active and inactive chromosome domains generally replicate at different times during S‐phase, this spatiotemporal regulation of chromatin assembly proteins may be an integral part of epigenetic inheritance. BioEssays 25:647–656, 2003. © 2003 Wiley Periodicals, Inc. (shrink)

Regarding the determination of vulnerability, the bioethics community has univocally jettisoned “labelled groups”, groups whose membership confers a context-invariant “vulnerable” status to their members. While the usual reasons against the sole use of labelled groups to determine the vulnerability of individuals are sound, labelled groups as exemplars of vulnerability can play indispensable roles in bioethical reasoning. In this article, I argue against the wholesale jettisoning of labelled groups by showing how they can be useful.

This chapter sketches the outlines of what a reasonable form of nativism might look like. The neuroconstructivists' challenge indicates that some misunderstanding continues to exist among certain self-titled nonnativists over what it is that practicing nativists actually claim, together with a mistaken belief that current neurodevelopmental data is not or cannot be compatible with the nativist program. Both these issues are addressed by first providing further explication of the claims of practicing nativists, and then showing how these claims provide the (...) basis for a reasonable nativism that is fully cognizant of and consistent with empirical data from all the developmental sciences, neuroconstructivism included. (shrink)

Rapid technological advances have produced a variety of novel techniques that allow a comprehensive assessment of brain function to be combined with detailed information about brain structure and connectivity. Any assessment that is based on exhibited behavior after brain injury will be prone to error for a number of reasons. These questions are explored in the context of recent studies in both healthy populations and brain injured patients that have sought to investigate covert awareness through the use of functional neuroimaging. (...) Those circumstances in which functional magnetic resonance imaging data can be used to infer awareness in the absence of a behavioral response are contrasted with those circumstances in which it cannot. This distinction is fundamental for understanding and interpreting patterns of brain activity following acute brain injury and has implications for clinical care, diagnosis, prognosis, and medicolegal decision-making after serious brain injury. (shrink)