Scaling of pattern with size has been described and studied for over a century, yet its molecular basis is understood in only a few cases. In a recent, elegant study, Inomata and colleagues proposed a new model explaining how bone morphogenic protein (BMP) activity gradient scales with embryo size in the early Xenopus laevis embryo. We discuss their results in conjunction with an alternative model we proposed previously. The expansion‐repression mechanism (ExR) provides a conceptual framework unifying both mechanisms. Results of (...) Inomata and colleagues implicate the chordin‐stabilizing protein sizzled as the expander molecule enabling scaling, while we attributed this role to the BMP ligand Admp. The two expanders may work in concert, as suggested by the mathematical model of Inomata et al. We discuss approaches for differentiating the contribution of sizzled and Admp to pattern scaling. (shrink)

A travers les faits et manifestations considérés comme irrationnels par l'entendement scientiste et positiviste, on décèle du point de vue de la philosophie de l'esprit une rationalité poétique qui est à l'oeuvre dans tout esprit humain. Ce super-rationalisme qui intègre en même temps le sensible et le rationnel obéit à une logique du symbolisme qu'on retrouve dans l'ontologie africaine. L'africanisme ontologique induit une philosophie de l'invisible où la connaissance intuitive libère l'esprit du dogmatisme rationaliste. Il permet d'appréhender l'Etre dans sa (...) totalité en examinant la question du rapport à soi, et du rapport à l'autre à travers la figure du sage africain. Aujourd'hui, la rencontre des cultures et des civilisations permet un croisement des rationalités et une pluralité de valeurs qui fondent le nouvel humanisme dont nous nous réclamons. Un humanisme spirituel basé sur le respect et la compréhension de l'autre par la différence de sa pensée et de ses attributs socio-psychologiques. (shrink)

Clinical medicine is an inexact science. In situations of uncertainty, we often ask an experienced colleague for a second opinion. But what if one could effectively call upon the experience of thou...

The assessment of student learning is widely regarded with suspicion. Philosophers in particular have been reluctant to take this practice seriously. The essay reviews an ongoing effort to assess the development of philosophical dispositions among undergraduate students at a religiously affiliated liberal arts college. The procedure used in this effort as well as the results obtained so far strongly suggest that the deep learning valued most highly by philosophy teachers can be measured without harm to the teaching enterprise. The essay (...) argues that in light of a current cultural climate that fails to recognize the value of our enterprise, philosophers would be well advised to clearly define our particular learning goals, develop our own instruments, and to exercise more initiative in assessing our students learning. (shrink)

Unlike some other reproductions of classic texts (1) We have not used OCR(Optical Character Recognition), as this leads to bad quality books with introduced typos. (2) In books where there are images such as portraits, maps, sketches etc We have endeavoured to keep the quality of these images, so they represent accurately the original artefact. Although occasionally there may be certain imperfections with these old texts, we feel they deserve to be made available for future generations to enjoy.

1. Imre Pinḥas ha-shalem -- 2. Liḳuṭe Imre Pinḥas. Mafteḥot.

Forcing extensions yield models of ZFC in which a long sequence of club subsets of ω 1 has the following property: every subsequence of size ℵ 1 has a finite intersection.

This paper seeks to explore the significance of a specific kind of religious experience for the rationality of religious belief. The context for this is a gap between what is often allowed as rational and what is embraced as certain in the life of faith. The claim to certainty at issue is related to the work and experience of the Holy Spirit; this experience has a structure which is explored phenomenologically. Thereafter various ways of cashing in the epistemic value of (...) the purported claim to certainty are examined. (shrink)

The theories of complexity comprise a system of great breadth. But what is included under this umbrella? Here we attempt a portrait of complexity theory, seen through the lens of complexity theory itself. That is, we portray the subject as an evolving complex dynamical system, or social network, with bifurcations, emergent properties, and so on. This is a capsule history covering the twentieth century. Extensive background data may be seen at www.visual-chaos.org/complexity.

1. ʻAmud Torah. ʻAmud ʻavodah, ḥ. 1 -- 2. ʻAmud ʻavodah, ḥ. 2. ʻAmud gemilut ḥasadim.

This volume includes all Dewey's writings for 1938 except for Logic: The Theory of Inquiry, as well as his 1939 Freedom and Culture, Theory of Valuation, and two items from Intelligence in the Modern World. Freedom and Culture presents, as Steven M. Cahn points out, the essence of his philosophical position: a commitment to a free society, critical intelligence, and the education required for their advance.

Ainslie's account of willpower addresses many important mechanisms. We argue that a model of willpower should be grounded in general psychological principles and with a primary focus on their interplay. We discuss the reflective-impulsive model that covers willpower and impulsiveness as special constellations of processes that govern various forms of cognition and behavior.

Ḥeleḳ Rishon, kerekh 1. Teshuvot ha-shayakhot le-Miḳra Midrash ṿe-deʻot ṿe-tsoraf la-hen Sefer Minḥat ḳenaʼot le-R. Aba Mari de-Lunil [Haḳdamah-pereḳ 37] -- Ḥeleḳ Rishon, kerekh 2. Miḳra Midrash ṿe-deʻot Teshuvot ha-shayakhot le-Miḳra Midrash ṿe-deʻot ṿe-tsoraf la-hen Sefer Minḥat ḳenaʼot le-R. Aba Mari de-Lunil [pereḳ 38-pereḳ 127] -- Ḥeleḳ sheni. Teshuvot ha-shayakhot le-Masekhet Berakhot ṿe-Seder Zeraʻim -- Ḥeleḳ shelishi. Teshuvot ha-shayakhot le-Masekhet Shabat ṿe-ʻEruvin.

The Exalted Fath: Ha-Emunah ha-Ramah Transleted by Solomon Ibn Lavi, Ha-Emunah ha-Nissaʼah Transleted by Samuel Ibn Matut, The Anonymous Commentary to HaEmunah ha-Ramah.

El budismo. Peter Harvey. Cambridge University Press, Madrid 1998. 468 pp. Ptas 2,995. ISBN 84-8323-014-3.