The paper is devoted to a conceptual model of cell patterning, based on a generalized notion of the epigenetic code of a cell determining its state. We introduce the concept of signaling depending both upon the spatial distance between cells and the distance between their cell states (s-distance); signaling can repel cells in the space of cell states (s-space) or attract them. The influence of different types of repelling signaling on the evolution of cells is considered. Stabilizing signaling, namely a (...) signaling monotonically decreasing with s-distance, causes the restoring of cell states after perturbations; destabilizing signaling, i.e., the one in which the signaling monotonically increases with s-distance, causes the appearance of pairs of cells with alternating cell states (one close to the state conventionally called “head”, and another close to the “tail” state). Non-monotonic (in s-space) signaling splits the cells into groups. The model shows that different types of signaling may provide different types of cellular patterns. General principles for applying this model to complex cellular structures are discussed. (shrink)

Can we respond to injustices in the world in ways that do more than just address their consequences? In this book, Brooke A. Ackerly argues that what to do about injustice is not just an ethical or moral question, but a political question about assuming responsibility for injustice. Ultimately, Just Responsibility offers a theory of global injustice and political responsibility that can guide action.

The growing gap between demands and resources is putting immense pressure on all government spending in Sweden. The gap is especially apparent in care and services for elderly people in light of the rapid aging of the population. The article considers the decisions and priorities concerning resource allocation in the welfare sector in general and in elderly care in particular. The aim is to describe the political and administrative setting and to provide a conceptual structure that outlines the nature of (...) the problem. Various levels of decision making are identified and discussed in the context of political accountability. Current transitions in elderly care are described with respect to service provision, marketisation, coverage rates, and eligibility standards. Basic principles of distribution are highlighted in order to clarify some central concepts of efficiency and justice, and a number of strategies for actual prioritising are identified. The article concludes with an endorsement of more conscious decisions in resource allocation. Existing knowledge and information concerning the effects of various strategies must be utilised, and the values and assumptions used for setting priorities must be made explicit. (shrink)

El artículo expone dos visiones acerca de la legitimidad del castigo en contextos de exclusión social. En la primera parte, uno de los autores defiende la idea de que los Estados que incumplen con obligaciones legales previas no pueden inculpar a quienes cometan delitos vinculados con ese incumplimiento. No pueden hacerlo porque no tienen el estatus moral para hacerlo de acuerdo a dos objeciones: la de complicidad y la de hipocresía. En la segunda parte, la segunda autora critica esta solución (...) al sostener que la falta de reciprocidad que caracteriza a la relación política vuelve inaplicables las objeciones de hipocresía y complicidad al ámbito del castigo penal estatal. (shrink)

The physician charter on medical professionalism creates standards of ethical behaviour for physicians and has been endorsed by professional organisations worldwide. It is based on the cardinal principles of the primacy of patient welfare, patient autonomy, and social welfare. There has been little discussion in the bioethics community of the doctrine of the charter and none from a Jewish ethical perspective. In this essay the authors discuss the obligations of the charter from a Jewish ethical viewpoint and call on other (...) cultures to develop their own unique perspectives on this important document. (shrink)

In recent years attention to the philosophical and literary production of P. A. Florenskii has become commonplace. The thinker's intellectual legacy is very great. In September 1919, Florenskii wrote a prospectus for a collection of his own writings, which would have amounted to nineteen volumes. The collection was not published, for a number of reasons; nonetheless, many of the philosopher's works did come out during his lifetime. Florenskii's writing, published in small editions and scattered among various journals, are still quite (...) inaccessible to readers. (shrink)

This article must open with a Warning. In face of the positive information which the sciences supply, the philosophical contribution to this problem will seem disappointingly negative, or at least mine will do so. For I shall insist, and I think we can only rightly insist, that the philosopher is not yet in a position to produce a satisfactory positive theory of the relation between mind and body. And I shall annoy many of you further by insisting that the old-fashioned (...) “dualism” has not really been disproved. However, even if you do not agree with me, it is at any rate a good general piece of advice that, when we are confronted with a philosophical view which has maintained its ground for a very long time but seems to ourselves or to our generation very unreasonable, we should look specially carefully to find the positive grounds which have made so apparently unplausible a doctrine seem true to so many competent thinkers. (shrink)

Estudio sistemático sobre la imagen y sus complejas relaciones con el lenguaje verbal, partiendo de una crítica al logocentrismo en su vertiente racionalista -que reduce el conocimiento y el pensamiento al discurso lingüístico- para desembocar en una teoría de la representación. El autor sostiene que la imagen va más allá de la representación al tornarse presencia, basándose en el examen de pensadores clásicos y teóricos actuales que han abordado cuestiones afines. Propone una teoría de la imagen que no se ciñe (...) sólo a lo visual, sino que reconoce las dimensiones no visuales de lo imaginal: "el principal objetivo de este libro es contribuir a la construcción de una filosofía de la imagen. Hoy en día es ya una necesidad urgente contar con un aparato conceptual que nos permita afrontar las distintas modalidades de lo imaginal, que aparecen en ámbitos tan diversos como la intimidad psicológica, la ciencia, la filosofía, la comunicación masiva, la religión, la educación, la propaganda o el arte". (shrink)

After the events of 11 September 2001 and the anthrax letters, terrorism and bioterrorism have become the number one issue and motivation for all sorts of discussions and actions within the USA and in the rest of the world. Therefore, it is no wonder that bioterrorism and the threat of chemical weapons are prevalent issues in bioethical debates throughout the world and especially in the USA.In the Wake of Terror tries to give an American perspective on the most important bioethical (...) issues connected with terrorism and bioterrorism. The book is from the series Basic Bioethics published by the MIT press. The series editors …. (shrink)

Contributed research papers presented at National Seminar jointly organized by Somanth Sanskrit University, Veraval and Sanskrit Sahitya Akadami at Gandhinagar on February 21-22, 2022.

We construct a machine that knows its own code, at the price of not knowing its own factivity.

Книгата предлага някои оригинални идеи по вечни философски въпроси, които вълнуват човешката мисъл от древността досега.

In this paper we aim to show that phenomenal consciousness is realized by a particular level of brain operational organization and that understanding human consciousness requires a description of the laws of the immediately underlying neural collective phenomena, the nested hierarchy of electromagnetic fields of brain activity – operational architectonics. We argue that the subjective mental reality and the objective neurobiological reality, although seemingly worlds apart, are intimately connected along a unified metastable continuum and are both guided by the universal (...) laws of the physical world such as criticality, self-organization and emergence. (shrink)

Truth-talk exhibits certain features that render it philosophically suspect and motivate a deflationary account. I offer a new formulation of deflationism that explains truth-talk in terms of semantic pretense. This amounts to a fictionalist account of truth-talk but avoids an error-theoretic interpretation and its resulting incoherence. The pretense analysis fits especially well with deflationism’s central commitment, and it handles truth-talk’s unusual features effectively. In particular, this approach suggests an interesting strategy for dealing with the Liar paradox. This version of deflationism (...) has advantages over the formulations currently available in the literature, mainly because it offers a more satisfying account of the generalizing role deflationary views take as truth-talk’s central function. Explaining the notion of truth in terms of pretense generates some special concerns, but none we cannot address through careful consideration of how pretense operates in truth-talk and of the attitudes instances of pretending involve. (shrink)

In The Face of Emotions, which was Carroll Izard’s first major attempt at elaborating his differential emotions theory (DET), he stated that the book “presents a theoretical framework for the study of emotions and their role in personality and interpersonal processes.” Yet, over the years, his contribution to personality theory has generally been overshadowed by the attention focused on his views on facial expressions and the structure of emotions. This article will begin with a brief overview of the DET perspective (...) on personality development. Then, it will examine how the DET framework can be used to organize recent findings from three lines of research on adult personality. It will conclude with suggestions for future research as well as some personal recollections. (shrink)

In nursing ethics the role of narratives and dialogue has become more prominent in recent years. The purpose of this article is to illuminate a relational-narrative approach to ethics in the context of palliative nursing. The case study presented concerns a difficult relationship between oncology nurses and a husband whose wife was hospitalized with cancer. The husband’s narrative is an expression of depression, social isolation and the loss of hope. He found no meaning in the process of dying and death. (...) The oncology nurses were not able to recognize his emotional and existential problems. A narrative perspective inspired by relational ethics indicates that participants may develop a relational narrative that seeks good for all involved in a situation. In palliative nursing this entails open communication about the fragility of life and approaching death. In relational narratives, answers to these ethical dilemmas are co-authored, contingent and contextual. (shrink)

Публикация рассчитана как на специалистов, так и на широкий круг читателей.

The persistent educational challenges that fractions pose call for developing novel instructional methods to better prepare students for fraction learning. Here, we examined the effects of a 24-session, Cuisenaire rod intervention on a building block for symbolic fraction knowledge, continuous and discrete non-symbolic proportional reasoning, in children who have yet to receive fraction instruction. Participants were 34 second-graders who attended the intervention (intervention group) and 15 children who did not participate in any sessions (control group). As attendance at the intervention (...) sessions was irregular (median = 15.6 sessions, range = 1–24), we specifically examined the effect of the number of sessions completed on their non-symbolic proportional reasoning. Our results showed that children who attended a larger number of sessions increased their ability to compare non-symbolic continuous proportions. However, contrary to our expectations, they also decreased their ability to compare misleading discretized proportions. In contrast, children in the Control group did not show any change in their performance. These results provide further evidence on the malleability of non-symbolic continuous proportional reasoning and highlight the rigidity of counting knowledge interference on discrete proportional reasoning. (shrink)

La psicología contemporánea parece caracterizarse desde sus propios orígenes por la multiplicidad de sus contenidos, además de por su casi infinita fragmentación en corrientes encontradas. Esto crea importantes dificultades, no sólo a quienes quieran tener una primera aproximación, sino también a los especialistas, que muchas veces no llegan a una opinión suficientemente clara sobre la naturaleza epistemológica de la psicología, ni sobre su unidad disciplinar. Esta obra, sin descuidar el problema global, se centra en un aspecto particular: el que presenta (...) la praxis de la psicología, en particular la psicoterapia y sus fundamentos teóricos. Se pone especial interés en una visión crítica del psicoanálisis, punto de referencia inevitable (positivo o negativo) para la mayoría de las corrientes de psicoterapia. Pero este intento de esclarecimiento epistemológico y práctico se lleva a cabo desde un punto de vista original: a la luz del pensamiento de Santo Tomás de Aquino (1225-1274), conocido como uno de los más grandes teólogos y filósofos de la Iglesia Católica. Las calidades del Aquinate como epistemológico son sobradamente conocidas. Menos conocida es su faceta de psicólogo, que esta obra quiere poner de manifiesto con gran detalle para evidenciar la actualidad de las líneas maestras de la psicología de Santo Tomás, como también la posibilidad de practicar hoy la psicología bajo la guía fundamental del Doctor Humanitatis.\n. (shrink)

Heleno Saña aborda los interrogantes y arcanos de la condición humana en sus más diversas manifestaciones. Ofrece una vasta síntesis de lo que ha sido el Hombre desde sus orígenes hasta nuestros días. Esta perspectiva integral le permite a la vez explicar el desarrollo de la Humanidad y de la historia universal en su conjunto. La nueva obra de este reputado filósofo constituye una excelente guía no sólo para descifrar las profundidades y misterios del alma humana, sus conflictos y sus (...) dramas internos, sino también para superarlos. Quien se asome a las páginas de este libro estará en condiciones de conocerse a sí mismo y de dar a su vida el mayor sentido posible, a partir del sólido apoyo de la reflexión filosófica y antropológica. (shrink)

The questions of this article are: what can we learn from deliberative democratic theory, its critics, the practices of local deliberative communities, the needs of potential participants, and the experiences of virtual communities that would be useful in designing a technology-facilitated institution for global civil society that is deliberative and democratic in its values? And what is the appropriate design of such an online institution so that it will be attentive to the undemocratic forces enabled by power inequalities that can (...) emerge in discursive communities? I answer these questions with an institutional innovation that meets a need of global civil society and that is responsive to critics of deliberative democratic theory and attentive to the particular agents engaged in women's human rights activism. (shrink)

Exposition of Advaita based on selections from the Vedāntaparibhāsā by Dharmarājādhvarindra, 17th cent., Yatīndramatadīpikā by Śrīnivāsadāsa, 17th cent., and Śrībhāsya by Rāmānuja, 1017-1137; with profuse quotations.

Recent discussion on Corporate Social Responsibility (CSR) mainly focuses on two aspects of CSR: from a technical perspective, CSR aims to improve ethical standards in the organizational decision-making process, and should guarantee that management practices are in accordance with commonly accepted standards of behavior. From a political perspective, CSR describes corporate engagement with ecological and social issues that extend beyond the firm's economic activities. The latter perspective in particular leaves unclear whether such corporate contributions to solve environmental and societal problems (...) should be seen as voluntary additional services or whether corporations bear specific duties in this field.Based on the tenet of subsidiarity derived from Catholic thought, this article emphasizes that the common interpretation of CSR should be extended by a third perspective that addresses corporations as intermediate actors bearing specific subsidiary co-responsibilities in society. (shrink)

Книга представляет собой исследование, где предпринимается попытка на основе детальной проработки первоисточников и воспроизведения основных ходов мысли и интуиций Гегеля и позднего Шеллинга провести сравнительный анализ их учений об абсолюте.