A team of US researchers recently reported the design, assembly and in vivo functionality of a synthetic chromosome III (SynIII) for the yeast Saccharomyces cerevisiae. The synthetic chromosome was assembled bottom‐up from DNA oligomers by teams of students working over several years with researchers as the first part of an international synthetic yeast genome project. Embedded into the sequence of the synthetic chromosome are multiple design changes that include a novel in‐built recombination scheme that can be induced to catalyse intra‐chromosomal (...) rearrangements in a variety of different conditions. This system, along with the other synthetic sequence changes, is intended to aid researchers develop a deeper understanding of how genomes function and find new ways to exploit yeast in future biotechnologies. The landmark of the first synthesised designer eukaryote chromosome, and the power of its massively parallel recombination system, provide new perspectives on the future of synthetic biology and genome research. (shrink)

The radical redefinition of the landscape of physics that followed the contributions of Niels Bohr and Werner Heisenberg at the start of the 20th century led to plethora [of] new perspectives on age-old metaphysical questions on determinism and the nature of reality. The main contention of this article is that the work of Gilbert Simondon - whose magnum opus possesses a scope uniting the most basic philosophical concerns with the most recent breakthroughs in natural sciences - is highly relevant for (...) an adequate understanding of the split between determinism and indeterminism, as well as the underlying presuppositions which have driven some influential contributions to this topic. To this end, the article shows that the more deterministic interpretation of quantum mechanics offered by David Bohm and Louis de Broglie proves to be a valuable reference point for a more precise use and understanding of Simondon'ss transductive logic - especially when its philosophical lapses are considered closely. Finally, following the considerations of both thinkers, we aim at a more precise reconsideration of the stakes of indeterminism in modern physics, as well as a restructuration of what is often understood as a polarization. (shrink)

The physician charter on medical professionalism creates standards of ethical behaviour for physicians and has been endorsed by professional organisations worldwide. It is based on the cardinal principles of the primacy of patient welfare, patient autonomy, and social welfare. There has been little discussion in the bioethics community of the doctrine of the charter and none from a Jewish ethical perspective. In this essay the authors discuss the obligations of the charter from a Jewish ethical viewpoint and call on other (...) cultures to develop their own unique perspectives on this important document. (shrink)

Moral education through service learning at post-secondary level is an important but under-researched field. Most existing studies center on its learning outcomes like academic progress, personal development, communication, and leadership skills, with only a few evaluating the moral development of college students participating in service-learning projects. The lack of study on moral development in service learning indicates a need for clarification of the theoretical underpinnings of service learning, John Dewey's ideas on moral growth, in particular his model of moral imagination (...) and the implications thereof, for current service-learning research and practice. We argue that Dewey's work here can help strengthen .. (shrink)

For centuries, philosophers and theologians debated how to reconcile the existence of an all-powerful, all-loving, and ever-present God with the problem of evil. However, the question of why the righteous suffer remains unanswered. Given the omnipresence of God, one wonders why the sufferers experience what seems like God’s absence in their adversity. This study presents a theodicy of narrative analytic theology because the experiences of the saints of old compel us to rethink our approach to the problem of evil from (...) the ‘God’s-eye view’ to the experiential and existential worries of the sufferer. The study looks at the story of Job and Daniel and his friends in Babylon. The narrative theodicy approach helps us understand why the righteous never denounced God in the Old Testament. The New Testament, in line with the Old Testament, reveals a suffering motif of the saints, which includes participation in the atoning work of Christ and the purification of the souls of the sufferer. Nevertheless, it seems some evils are pointless. The sufferers do not see their suffering as a punishment or a weakness from God but as a distraction and a test to perfect their covenantal relationship with the Triune. Ultimately, the suffering of the righteous will be overcome at the eschaton. (shrink)

v. 1. Edinyĭ i︠a︡zyk chelovechestva. --.

Women; ethics; religious aspects; ethics.