Music as an Imitation of Harmonious Balance.

The concept of human gene therapy came on the heels of fundamental discoveries on the nature and working of the gene. However, realistic prospects to correct the underlying cause of recessive genetic disorders through the transfer of wild‐type alleles of defective genes had to wait for the arrival of recombinant DNA technology. These techniques permitted the isolation and insertion of genes into the first recombinant delivery systems. The realization that viruses are natural gene carriers provided inspiration for gene therapy and, (...) as engineered vectors, viruses became prominent gene delivery vehicles. Nonetheless, when put in the context of human and non‐human primate studies, all vectors fell short of success regardless of their viral or non‐viral origin. Recognition of issues such as inefficient gene transfer and short‐lived or scant expression in the relevant cell type(s) prompted researchers to refine and develop several gene delivery systems, in particular those based on retroviruses, adeno‐associated viruses and adenoviruses. Concomitantly, available technology was deployed to tackle disorders that require few genetically corrected cells to attain therapy. BioEssays 27: 506–517, 2005. © 2005 Wiley periodicals, Inc. (shrink)

This new and revised edition provides a comprehensive dictionary of Indian philosophical terms. Terms are provided in both devanagari and roman transliteration along with their English translations.

A Concise Companion to Feminist Theory introduces readers to the broad scope of feminist theory over the past 35 years.

The Erez Series, A Concise Guide to Mahshava contains an anthology of passages that address profound questions that have challenged the greatest minds throughout Jewish history. We focus not only on the content of the passages and descriptions of events, but on responses to questions such as: Why? What is the meaning of this? Much of the material brought here relates to the content of the other books in this series, but this volume also contains a selection of various (...) problems and responses to general questions relating to the nation and the individual, to life, fate, and purpose. Essentially, one will find here a series of meditations and contemplations that are relevant to anyone insofar as he contemplates his own humanity. The book draws from the writings of many authors that relate, each in their own way, to these essential questions. The array of sources includes works composed since the time of the Sages, beginning approximately in the eighth century, until the twentieth century. One will also find here thoughts and ideas from people who lived more recently, up to the present day. Features: Carefully curated sources from the wide variety of Jewish approaches Summaries and explanations that distill complex concepts Concise biographies of the great thinkers of Jewish history Aphorisms and poetry that add layers of meaning English bibliography - delve further into texts that pique your curiosity Full integration with other Concise Guide volumes The Erez Series is comprised of the Concise Guides to the full gamut of Jewish thought, from the Torah to modern halakha (Jewish law) and Mahshava (Jewish philosophy). The late Rabbi Adin Even Israel Steinsaltz zt"l was one of the leading thinkers of the modern age and the most prolific author of Jewish thought and commentary since the middle ages. The Erez Series distills the essence of 4 of the principal schools of the Jewish tradition Torah, the Sages (Hazal), Halakha, and Mahshava as a tool for review or introduction to the world of Jewish thought. (shrink)

This authoritative collection surveys the teachings of Confucius, and illustrates his importance throughout Chinese history in one focused and incisive volume. A Concise Companion to Confucius offers a succinct introduction to one of East Asia’s most widely-revered historical figures, providing essential coverage of his legacy at a manageable length. The volume embraces Confucius as philosopher, teacher, politician, and sage, and curates a collection of key perspectives on his life and teachings from a team of distinguished scholars in philosophy, history, (...) religious studies, and the history of art. Taken together, chapters encourage specialists to read across disciplinary boundaries, provide nuanced paths of introduction for students, and engage interested readers who want to expand their understanding of the great Chinese master. Divided into four distinct sections, the Concise Companion depicts a coherent figure of Confucius by examining his diverse representations from antiquity through to the modern world. Readers are guided through the intellectual and cultural influences that helped shape the development of Confucian philosophy and its reception among late imperial literati in medieval China. Later essays consider Confucius’s engagement with topics such as warfare, women, and Western philosophy, which remain fruitful avenues of philosophical inquiry today. The collection concludes by exploring the significance of Confucian thought in East Asia’s contemporary landscape and the major intellectual movements which are reviving and rethinking his work for the twenty-first century. An indispensable resource, A Concise Companion to Confucius blazes an authoritative trail through centuries of scholarship to offer exceptional insight into one of history’s earliest and most influential ancient philosophers. A Concise Companion to Confucius: Provides readers with a broad range of perspectives on the ancient philosopher Traces the significance of Confucius throughout Chinese history—past, present, and future Offers a unique, interdisciplinary overview of Confucianism Curated by a team of distinguished scholars in philosophy, history, religious studies, and the history of art A Concise Companion to Confucius is an ideal text for undergraduate and graduate courses on Confucius and Confucianism. It is also fascinating and informative reading for anyone interested in learning more about one of history’s most influential philosophers. (shrink)

Tens of thousands of students have learned to be more discerning at constructing and evaluating arguments with the help of Patrick J. Hurley. Hurley’s lucid, friendly, yet thorough presentation has made A CONCISE INTRODUCTION TO LOGIC the most widely used logic text in North America. In addition, the book’s accompanying technological resources, such as CengageNOW and Learning Logic, include interactive exercises as well as video and audio clips to reinforce what you read in the book and hear in class. (...) In short, you’ll have all the assistance you need to become a more logical thinker and communicator. Important Notice: Media content referenced within the product description or the product text may not be available in the ebook version. (shrink)

This concise, authoritative encyclopedia from one of the world's most renowned theologians explores all the major themes in the philosophy of religion.

This short peer-reviewed text is a concise overview of neurodiversity, the natural diversity of human brain functioning including ways that are currently pathologized as disorders. The concept is essential to understanding humans and societies.

Popper [3] offers a qualitative definition of the relation “p q” = “p is (strictly) closer to the truth than (i.e., strictly more verisimilar than) q”, using the notions of truth (in the actual world) and classical logical consequence ( ), as follows.

This is a concise introductory textbook for a one semester course in the history and philosophy of mathematics. It is written for mathematics majors, philosophy students, history of science students and secondary school mathematics teachers. The only prerequisite is a solid command of pre-calculus mathematics. It is shorter than the standard textbooks in that area and thus more accessible to students who have trouble coping with vast amounts of reading. Furthermore, there are many detailed explanations of the important mathematical (...) procedures actually used by famous mathematicians, giving more mathematically talented students a greater opportunity to learn the history and philosophy by way of problem solving. Several important philosophical topics are pursued throughout the text, giving the student an opportunity to come to a full and consistent knowledge of their development. These topics include infinity, the nature of motion, and Platonism. This book offers, in fewer pages, a deep penetration into the key mathematical and philosophical aspects of the history of mathematics. (shrink)

Written in a relaxed, readable style, A Concise Introduction to Pure Mathematics leads students gently but firmly into the world of higher mathematics. It provides beginning undergraduates with a rigourous grounding in the basic tools and techniques of the discipline and prepares them for further more advanced studies in analysis, differential equations, and algebra. This edition contains additional material on secret codes, permutations, and prime numbers. It features more than 200 exercises, with many completely new. The text is organized (...) into relatively independent chapters, allowing instructors to tailor the book to meet their individual course needs. · Contains extra material concerning prime numbers, forming the basis for data encryption · Explores "Secret Codes" - one of today's most spectacular applications of pure mathematics Discusses Permutations and their importance in many topics in discrete mathematics. (shrink)

In this issue, Walter Sinnott-Armstrong and Franklin G. Miller argue that what makes killing wrong, when it is wrong, is not that it ends life, but that it causes complete and irreversible disability—what they call total disability. They hold that the wrongness of killing should be explained by reference to the harm that killing causes to the person who dies. And the only harm of this sort that killing causes, they argue, is the harm of being totally disabled: once one (...) is totally disabled, there is no further harm to one in losing one's life. It is no worse to be dead, and thus totally disabled, than it is to be totally disabled but alive.In fact, Sinnott-Armstrong and Miller concede that the story may be more complicated than this. For example, it may be that what makes killing wrong, when it is wrong, is not that it causes harm, but that it is intended to do so, or that it violates a right which protects against harm. But either way, harm plays a crucial role in explaining the wrongness of killing, and the relevant harm, they claim, is the harm of being disabled, not that of losing one's life.The Authors’ argument has important implications for medical ethics. Their view implies that killing a person need not be wrong when that person is already completely and irreversibly disabled. This suggests, for example, that the dead donor rule in organ donation is mistaken. Contrary to the rule, it could be morally permissible to harvest organs from a living donor provided that the donor is totally disabled. Harvesting organs will kill the donor, but it will not disable her, since the donor has no abilities left to lose.Four …. (shrink)

A concise yet rigorous introduction to logic and discrete mathematics. This book features a unique combination of comprehensive coverage of logic with a solid exposition of the most important fields of discrete mathematics, presenting material that has been tested and refined by the authors in university courses taught over more than a decade. The chapters on logic - propositional and first-order - provide a robust toolkit for logical reasoning, emphasizing the conceptual understanding of the language and the semantics of (...) classical logic as well as practical applications through the easy to understand and use deductive systems of Semantic Tableaux and Resolution. The chapters on set theory, number theory, combinatorics and graph theory combine the necessary minimum of theory with numerous examples and selected applications. Written in a clear and reader-friendly style, each section ends with an extensive set of exercises, most of them provided with complete solutions which are available in the accompanying solutions manual. Key Features: Suitable for a variety of courses for students in both Mathematics and Computer Science. Extensive, in-depth coverage of classical logic, combined with a solid exposition of a selection of the most important fields of discrete mathematics Concise, clear and uncluttered presentation with numerous examples. Covers some applications including cryptographic systems, discrete probability and network algorithms. Logic and Discrete Mathematics: A Concise Introduction is aimed mainly at undergraduate courses for students in mathematics and computer science, but the book will also be a valuable resource for graduate modules and for self-study. (shrink)

Encyclopedic dictionary of philosophy; includes brief biographies of prominent philosophers.

The first comprehensive account of Platonism in Antiquity, from the foundation of Plato's Academy in the fourth century BC to Late Antiquity. Written in a clear language, the book shows that Platonism is philosophically engaging and very influential in the history of philosophy. Useful for both students and scholars.

This brief and engaging introductory text treats philosophy as a dramatic and continuous story--a conversation about humankind's deepest and most persistent concerns, in which students are encouraged to participate. Tracing the exchange of ideas between history's key philosophers, Philosophical Conversations: A Concise Historical Introduction demonstrates that while constructing an argument or making a claim, one philosopher almost always has others in mind. The book addresses the fundamental questions of human life: Who are we? What can we know? How should (...) we live? and What sort of reality do we inhabit? Throughout, author Norman Melchert provides a generous selection of excerpts from major philosophical works and makes them more easily understandable with his lucid explanations. Extensive cross-references highlight the organizing themes and show students how philosophers have responded to each other's arguments. A more concise edition of Norman Melchert's The Great Conversation: A Historical Introduction to Philosophy, Fifth Edition, Philosophical Conversations is designed to be especially accessible and visually attractive to first- and second-year college students in introduction to philosophy courses. Enhanced by numerous pedagogical features, it offers: * Shorter and/or simplified presentations of much of the material * A second color that enlivens the text and makes it more visually interesting * An expanded art program featuring more than 100 photographs, illustrations, and cartoons * Classic art at the opening of each chapter * Numerous brief quotations from poets, politicians, and thinkers that underscore philosophical points and stimulate thought * Explanatory footnotes and basic study questions throughout * "Questions for Further Thought" at the end of each chapter * Key terms, boldfaced at their first appearance and collected at the end of each chapter and in a detailed glossary at the back of the book * "Sketches"--which provide glimpses of the ideas of various philosophers not already discussed in detail in the narrative--and "Profiles," which offer more in-depth looks at several thinkers, philosophical schools, and movements including Taoism, Zen, Jean-Paul Sartre, and Iris Murdoch * An Instructor's Manual and Test Bank on CD that highlights essential points and offers numerous exam questions. (shrink)

This deeply informed history traces the controversial record of "mercy-killing," a source of heated debate among doctors and laypeople alike. Dowbiggin examines evolving opinions about what constitutes a good death, taking into account the societal and religious values placed on sin, suffering, resignation, judgment, penance, and redemption. He also examines the bitter struggle between those who stress a right to compassionate and effective end-of-life care and those who define human life in terms of either biological criteria, utilitarian standards, a faith (...) in science, humane medical treatment, the principle of personal autonomy, or individual human rights. Considering both the influence of technological and behavioral changes in the practice of medicine and the public's surprising lack of awareness of death's many clinical and biological dimensions, this book raises profound personal and collective questions on the future of euthanasia. (shrink)

This Element aims to present an outline of mathematics and its history, with particular emphasis on events that shook up its philosophy. It ranges from the discovery of irrational numbers in ancient Greece to the nineteenth- and twentieth-century discoveries on the nature of infinity and proof. Recurring themes are intuition and logic, meaning and existence, and the discrete and the continuous. These themes have evolved under the influence of new mathematical discoveries and the story of their evolution is, to a (...) large extent, the story of philosophy of mathematics. (shrink)