Results for ' expanding hierarchy of selection'

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  1.  54
    Microevolution and macroevolution are not governed by the same processes.Douglas H. Erwin - 2009 - In Francisco José Ayala & Robert Arp, Contemporary debates in philosophy of biology. Malden, MA: Wiley-Blackwell. pp. 180--193.
    This chapter contains sections titled: The Domains of Microevolution and Macroevolution Changing Meanings of Macroevolution An Expanding Hierarchy of Selection Origins of Novelty Mass Extinctions Is Evolution Uniformitarian? Conclusions Postscript: Counterpoint References.
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  2.  85
    Group selection: The theory replaces the bogey man.David Sloan Wilson & Elliott Sober - 1994 - Behavioral and Brain Sciences 17 (4):639-654.
    In both biology and the human sciences, social groups are sometimes treated as adaptive units whose organization cannot be reduced to individual interactions. This group-level view is opposed by a more individualistic one that treats social organization as a byproduct of self-interest. According to biologists, group-level adaptations can evolve only by a process of natural selection at the group level. Most biologists rejected group selection as an important evolutionary force during the 1960s and 1970s but a positive literature (...)
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  3. Reintroducing group selection to the human behavioral sciences.David Sloan Wilson & Elliott Sober - 1994 - Behavioral and Brain Sciences 17 (4):585-608.
    In both biology and the human sciences, social groups are sometimes treated as adaptive units whose organization cannot be reduced to individual interactions. This group-level view is opposed by a more individualistic one that treats social organization as a byproduct of self-interest. According to biologists, group-level adaptations can evolve only by a process of natural selection at the group level. Most biologists rejected group selection as an important evolutionary force during the 1960s and 1970s but a positive literature (...)
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  4.  83
    A Type Hierarchy of Selection Processes for the Evaluation of Evolutionary Analogies.Barbara Gabriella Renzi - 2009 - Journal for General Philosophy of Science / Zeitschrift für Allgemeine Wissenschaftstheorie 40 (2):311-336.
    In this paper I propose a type-hierarchy approach to provide an intersubjective framework for the evaluation of evolutionary analogies. This approach develops David Hull’s and others’ attempts to provide full generalisation for selection processes, in order to show that sociocultural development and, particularly, scientific change can be considered as an instance of Darwinian selection. I argue that the recent work by Eileen Cornell Way on type hierarchies can offer the kind of generalisation needed to solve the main (...)
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  5.  32
    (1 other version)Are species intelligent?: Not a yes or no question.Jonathan Schull - 1990 - Behavioral and Brain Sciences 13 (1):94-108.
    Plant and animal species are information-processing entities of such complexity, integration, and adaptive competence that it may be scientifically fruitful to consider them intelligent. The possibility arises from the analogy between learning and evolution, and from recent developments in evolutionary science, psychology and cognitive science. Species are now described as spatiotemporally localized individuals in an expanded hierarchy of biological entities. Intentional and cognitive abilities are now ascribed to animal, human, and artificial intelligence systems that process information adaptively, and that (...)
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  6.  11
    The Personal Correspondence of Hildegard of Bingen: Letters of Hildegard of Bingen.Joseph L. Baird (ed.) - 2006 - Oxford University Press USA.
    Hildegard of Bingen was one of the most remarkable women of her day. From early childhood she experienced religious visions, and at the age of eight she entered a cloistered religious life in the Benedictine monastery of Disibondenberg. Eventually she not only became abbess of the community, but presided over the establishment of an important new convent near Bingen. All but forgotten for hundreds of years, Hildegard was rediscovered in the 1980s and since then her visionary writings have been widely (...)
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  7.  35
    Hierarchies of measure-theoretic ultrafilters.Michael Benedikt - 1999 - Annals of Pure and Applied Logic 97 (1-3):203-219.
    We study relations between measure-theoretic classes of ultrafilters, such as the Property M ultrafilters of [4], with other well-known ultrafilter classes. We define several classes of measure theoretic ultrafilters, of which the Property M ultrafilters are the strongest. We show which containments are provable in ZFC between these measure-theoretic ultrafilters and boolean combinations of well-known ultrafilters such as the selective, semi-selective, and P-point ultrafilters. We also list some of the containment results between measure-theoretic ultrafilters and several other ultrafilter classes, such (...)
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  8.  63
    Biological hierarchies, their birth, death and evolution by natural selection.Robert W. Korn - 2002 - Biology and Philosophy 17 (2):199-221.
    Description of the biologicalhierarchy of the organism has been extendedhere to included the evolutionary andecological sub-hierarchies with theirrespective levels in order to give a completehierarchical description of life. These newdescriptions include direction of formation,types of constraints, and dual levels. Constraints are produced at the macromolecularlevel of genes/proteins, some of which (a) aredescendent restraints which hold a hierarchytogether and others (b) interact horizontallywith selective agents at corresponding levelsof the niche. The organism is a dual levelconstrained by both the ecologicalsub-hierarchy (survival) (...)
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  9.  91
    The levels of selection debate: Philosophical issues.Samir Okasha - 2006 - Philosophy Compass 1 (1):74–85.
    For a number of years, the debate in evolutionary biology over the ’levels of selection’ has attracted intense interest from philosophers of science. The main question concerns the level of the biological hierarchy at which natural selection occurs. Does selection act on organisms, genes, groups, colonies, demes, species, or some combination of these? According to traditional Darwinian theory the answer is the organism -- it is the differential survival and reproduction of individual organisms that drives the (...)
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  10.  73
    The generality of Constructive Neutral Evolution.T. D. P. Brunet & W. Ford Doolittle - 2018 - Biology and Philosophy 33 (1-2):2.
    Constructive Neutral Evolution is an evolutionary mechanism that can explain much molecular inter-dependence and organismal complexity without assuming positive selection favoring such dependency or complexity, either directly or as a byproduct of adaptation. It differs from but complements other non-selective explanations for complexity, such as genetic drift and the Zero Force Evolutionary Law, by being ratchet-like in character. With CNE, purifying selection maintains dependencies or complexities that were neutrally evolved. Preliminary treatments use it to explain specific genetic and (...)
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  11. A general account of selection: Biology, immunology, and behavior.David L. Hull, Rodney E. Langman & Sigrid S. Glenn - 2001 - Behavioral and Brain Sciences 24 (3):511-528.
    Authors frequently refer to gene-based selection in biological evolution, the reaction of the immune system to antigens, and operant learning as exemplifying selection processes in the same sense of this term. However, as obvious as this claim may seem on the surface, setting out an account of “selection” that is general enough to incorporate all three of these processes without becoming so general as to be vacuous is far from easy. In this target article, we set out (...)
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  12.  51
    Gulliver’s Further Travels: The Necessity and Difficulty of a Hierarchical Theory of Selection.Stephen Jay Gould - 1998 - Philosophical Transactions of the Royal Society of London B: Biological Sciences 353 (1366):307-314.
    For principled and substantially philosophical reasons, based largely on his reform of natural history by inverting the Paleyan notion of overarching and purposeful beneficence in the construction of organisms, Darwin built his theory of selection at the single causal level of individual bodies engaged in unconscious struggle for their own reproductive success. But the central logic of the theory allows selection to work effectively on entities at several levels of a genealogical hierarchy, provided that they embody a (...)
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  13. Lessons from the Large Hadron Collider for model-based experimentation: the concept of a model of data acquisition and the scope of the hierarchy of models.Koray Karaca - 2018 - Synthese 195 (12):1-22.
    According to the hierarchy of models account of scientific experimentation developed by Patrick Suppes and elaborated by Deborah Mayo, theoretical considerations about the phenomena of interest are involved in an experiment through theoretical models that in turn relate to experimental data through data models, via the linkage of experimental models. In this paper, I dispute the HoM account in the context of present-day high-energy physics experiments. I argue that even though the HoM account aims to characterize experimentation as a (...)
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  14.  54
    Selection over classes of ordinals expanded by monadic predicates.Alexander Rabinovich & Amit Shomrat - 2010 - Annals of Pure and Applied Logic 161 (8):1006-1023.
    A monadic formula ψ is a selector for a monadic formula φ in a structure if ψ defines in a unique subset P of the domain and this P also satisfies φ in . If is a class of structures and φ is a selector for ψ in every , we say that φ is a selector for φ over .For a monadic formula φ and ordinals α≤ω1 and δ<ωω, we decide whether there exists a monadic formula ψ such that (...)
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  15. Philosophical foundations for the hierarchy of life.Deborah E. Shelton & Richard E. Michod - 2010 - Biology and Philosophy 25 (3):391-403.
    We review Evolution and the Levels of Selection by Samir Okasha. This important book provides a cohesive philosophical framework for understanding levels-of-selections problems in biology. Concerning evolutionary transitions, Okasha proposes that three stages characterize the shift from a lower level of selection to a higher one. We discuss the application of Okasha’s three-stage concept to the evolutionary transition from unicellularity to multicellularity in the volvocine green algae. Okasha’s concepts are a provocative step towards a more general understanding of (...)
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  16. Expanding the Child's Range of Open Futures: A Proposed Basis for the Ethical Assessment of Parental Genetic Trait Selections.Eric B. Schmidt - 2004 - Dissertation, University of Washington
    This dissertation considers the bases upon which ethical assessments of parental genetic trait selections for their children can be made. It argues that if parents engage in genetic trait selections, they must act to expand their child's range of open futures, not to constrict their child's range of open futures or to differentially shift their child's range of open futures. It contends that other proposed distinctions, including distinctions between normal and diseased states and between treatment selections and enhancement selections, do (...)
     
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  17.  15
    On friendship; being an expanded translation of the Nicomachean ethics, books VIII & IX. Aristotle - 1940 - Cambridge [Eng.]: The University press. Edited by Percival, Geoffrey & [From Old Catalog].
    This work has been selected by scholars as being culturally important and is part of the knowledge base of civilization as we know it. This work is in the public domain in the United States of America, and possibly other nations. Within the United States, you may freely copy and distribute this work, as no entity has a copyright on the body of the work. Scholars believe, and we concur, that this work is important enough to be preserved, reproduced, and (...)
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  18.  5
    Ordering Wisdom. The Hierarchy of Philosophical Discourse in Aquinas by Mark D. Jordan. [REVIEW]Antonio Moreno - 1988 - The Thomist 52 (4):745-749.
    In lieu of an abstract, here is a brief excerpt of the content:BOOK REVIEWS 745 and psycholOgical doctrine developed in Bks. I-II in terms of the traditional theme of macrocosm and microcosm. Theologically, the author understands the classical gods as symbolizing intellects, heavenly bodies, or spirits. The allegorizing tendencies of Porphyry and even Proclus are much in evidence, as abundant citation of parallel texts demonstrates. The most important psychological doctrine inherited from the Neoplatonists, albeit greatly simplified and heavily allegorized, is (...)
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  19.  10
    Exploring the Use of Selection, Optimization, and Compensation Strategies Beyond the Individual Level in a Workplace Context – A Qualitative Case Study.Iben Louise Karlsen, Vilhelm Borg & Annette Meng - 2022 - Frontiers in Psychology 13.
    Due to aging populations and the prolonging of working lives, the number of senior workers will increase. Therefore, this study investigates the use of SOC strategies across organizational levels as a means for senior workers to maintain workability and age successfully at work. The need to expand the perspective of the SOC model beyond the individual level, when applied to a work context, has been emphasized theoretically in the literature, nevertheless, SOC strategies have so far only been examined at the (...)
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  20.  59
    The parental obligation to expand a child's range of open futures when making genetic trait selections for their child.Eric B. Schmidt - 2007 - Bioethics 21 (4):191–197.
    ABSTRACT As parents become increasingly able to make genetic trait selections on behalf of their children, they will need ethical guidance in deciding what genetic traits to select. Dena Davis has argued that parents act unethically if they make selections that constrain their child's range of futures. But some selections may expand the child's range of futures. And other selections may shift the child's range of futures, without either constraining or expanding that range. I contend that not only would (...)
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  21.  18
    (2 other versions)Selections, dispositions and the problem of measurement.Mauricio Suárez - 2001 - Centre for Philosophy of Natural and Social Science.
    This paper expands on, and provides a qualified defence of, Arthur Fine’s selective interactions solution to the measurement problem. Fine’s approach must be understood against the background of the insolubility proof of the quantum measurement. I first defend the proof as an appropriate formal representation of the quantum measurement problem. Then I clarify the nature of selective interactions, and more generally selections, and I go on to offer three arguments in their favour. First, selections provide the only known solution to (...)
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  22.  48
    Statistical models for the induction and use of selectional preferences.Marc Light & Warren Greiff - 2002 - Cognitive Science 26 (3):269-281.
    Selectional preferences have a long history in both generative and computational linguistics. However, since the publication of Resnik's dissertation in 1993, a new approach has surfaced in the computational linguistics community. This new line of research combines knowledge represented in a pre‐defined semantic class hierarchy with statistical tools including information theory, statistical modeling, and Bayesian inference. These tools are used to learn selectional preferences from examples in a corpus. Instead of simple sets of semantic classes, selectional preferences are viewed (...)
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  23. What and where in the human visual system: Two hierarchies of visual modules.L. M. Vaina - 1990 - Synthese 83 (1):49-91.
    In this paper we focus on the modularity of visual functions in the human visual cortex, that is, the specific problems that the visual system must solve in order to achieve recognition of objects and visual space. The computational theory of early visual functions is briefly reviewed and is then used as a basis for suggesting computational constraints on the higher-level visual computations. The remainder of the paper presents neurological evidence for the existence of two visual systems in man, one (...)
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  24.  61
    The Role of Dominance Hierarchy in the Evolution of Social Species.Mahdi Muhammad Moosa & S. M. Minhaz Ud-Dean - 2011 - Journal for the Theory of Social Behaviour 41 (2):203-208.
    A number of animal species from different lineages live socially. One of the features of social living is the formation of dominance hierarchy. Despite its obvious benefit in the survival probability of the species, the hierarchical structureitself poses psychological and physiological burden leading to the chronic activation of stress related pathways. Considering these apparently conflicting observations, here we propose that social hierarchy can act as a selective force in the evolution of social species. We also discuss its role (...)
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  25.  15
    Portfolio Selection with respect to the Probabilistic Preference in Variable Risk Appetites: A Double-Hierarchy Analysis Method.Ruitao Gu, Qingjuan Chen & Qiaoyun Zhang - 2021 - Complexity 2021:1-14.
    Traditional portfolio selection models mainly obtain the optimized portfolio ratio by focusing on the prices of financial products. However, investors’ multiple preferences and risk appetites are also significant factors that should be taken into account. In consideration of these two factors simultaneously, we propose a double-hierarchy model in this paper. Specifically, the first hierarchy quantifies investors’ risk appetite based on a historical simulation method and probabilistic preference theory. This hierarchy can be utilized to describe investors’ variable (...)
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  26.  36
    Managed Care and the Expanding Scope of Primary Care Physicians' Duties: A Proposal to Redefine Explicitly the Standard of Care.Bernard Friedland - 1998 - Journal of Law, Medicine and Ethics 26 (2):100-112.
    Managed care has brought wide-ranging changes to the health care system. Some of these changes have been well publicized. Among them are the financial pressures that have resulted in numerous mergers of health care institutions, the restriction on the ability of patients to select their physician of choice, and the ever diminishing number of days that patients are permitted to stay in the hospital. Individual physicians, too, have been affected. For example, they are under pressure to see more patients per (...)
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  27.  10
    The emergence and use of expanded carrier screening in gamete donation: A new form of repro‐genetic selection.Nicky Hudson, Cathy Herbrand & Lorraine Culley - 2024 - Bioethics 39 (1):137-144.
    With the continued expansion and commercialisation of fertility treatments, the selection and matching of donors have become more sophisticated and technologised. As part of this landscape, new form of genetic screening: ‘expanded carrier screening’ (ECS) is being offered as a technique to avoid the risk of donors passing on genetic conditions to future offspring. Allowing donors to be tested for hundreds of genetic conditions simultaneously, ECS marks a considerable departure from traditional ‘family history’ models of screening, which rely on (...)
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  28. Quantum Selections, Propensities and the Problem of Measurement.Mauricio Suárez - 2004 - British Journal for the Philosophy of Science 55 (2):219-255.
    This paper expands on, and provides a qualified defence of, Arthur Fine's selective interactions solution to the measurement problem. Fine's approach must be understood against the background of the insolubility proof of the quantum measurement. I first defend the proof as an appropriate formal representation of the quantum measurement problem. The nature of selective interactions, and more generally selections, is then clarified, and three arguments in their favour are offered. First, selections provide the only known solution to the measurement problem (...)
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  29.  7
    Expanding Philosophical Horizons: An Anthology of Nontraditional Writings.Max O. Hallman - 1995
    This anthology includes 42 selections from a wide variety of cultural backgrounds and historical periods. The text is not limited to Western material; it also includes Native American, African-American, Hispanic and feminist selections. While quite diverse historically and culturally, the readings are chosen for their readability and philosophical significance. To facilitate incorporation into existing courses, the selections are arranged in six chapters that correspond to traditional philosophical categories: self identity, knowledge and truth, creation and reality, ethics, politics and religion.
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  30. Alternative formulations of multilevel selection.John Damuth & I. Lorraine Heisler - 1988 - Biology and Philosophy 3 (4):407-430.
    Hierarchical expansions of the theory of natural selection exist in two distinct bodies of thought in evolutionary biology, the group selection and the species selection traditions. Both traditions share the point of view that the principles of natural selection apply at levels of biological organization above the level of the individual organism. This leads them both to considermultilevel selection situations, where selection is occurring simultaneously at more than one level. Impeding unification of the theoretical (...)
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  31.  27
    Expanded glutamines and neurodegeneration – a gain of insight.Gillian Bates - 1996 - Bioessays 18 (3):175-178.
    Glutamine repeat expansion has been established as the mutation underlying five inherited neurodegenerative diseases. The mechanism by which this apparently universal mutation, in ubiquitously expressed proteins, causes highly selective neurodegeneration is unknown. The proteins containing the glutamine expansions are otherwise unrelated and likely to have different functions. Two recently published papers(1,2) provide evidence of a conformational change occurring in polyglutamine expansions, which may allow novel interactions and is consistent with a toxic gain‐of‐function hypothesis. HAP1, a protein that interacts with huntingtin (...)
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  32.  98
    Hierarchy maintenance, coalition formation, and the origins of altruistic punishment.Yasha Rohwer - 2007 - Philosophy of Science 74 (5):802-812.
    Game theory has played a critical role in elucidating the evolutionary origins of social behavior. Sober and Wilson model altruism as a prisoner's dilemma and claim that this model indicates that altruism arose from group selection pressures. Sober and Wilson also suggest that the prisoner's dilemma model can be used to characterize punishment; hence, punishment too originated from group selection pressures. However, empirical evidence suggests that a group selection model of the origins of altruistic punishment may be (...)
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  33.  41
    Philosophy of religion: selected readings.William L. Rowe (ed.) - 1972 - New York,: Harcourt Brace Jovanovich.
    THE AIM OF THE VOLUME IS TO INTRODUCE STUDENTS TO THE PHILOSOPHY OF RELIGION BY ACQUAINTING THEM WITH THE WRITINGS OF SOME OF THE THINKERS WHO HAVE MADE SUBSTANTIAL CONTRIBUTIONS IN THIS AREA. THIS NEW EDITION EXPANDS THE RANGE OF TOPICS BY INCLUDING AN ENTIRELY NEW CHAPTER ON DEATH AND IMMORTALITY AND A NEW SUBSECTION ON THE MORAL ARGUMENT. THERE IS ALSO SOME NEW MATERIAL ON WITTGENSTEIN AND FIDEISM, RELIGIOUS PLURALISM, AND FAITH AND THE NEED FOR EVIDENCE. ALMOST EVERY CHAPTER (...)
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  34.  30
    Topic/Subject Coreference in the Hierarchy of Japanese Complex Sentences.Alastair Butler, Chidori Nakamura & Kei Yoshimoto - 2009 - In Hiromitsu Hattori, Takahiro Kawamura, Tsuyoshi Ide, Makoto Yokoo & Yohei Murakami, New Frontiers in Artificial Intelligence: JSAI 2008 Conference and Workshops, Asahikawa, Japan, June 11-13, 2008, Revised Selected Papers. Springer. pp. 119--132.
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  35.  76
    The new technology and its human impact.Umberto Colombo - 1989 - World Futures 27 (1):25-32.
    In the years that have passed since publication of the Club of Rome's seminal report "Limits to Growth," the issues raised in terms of development, resource use and the environment have become ever more pressing. The potential of advances in science and technology to affect all aspects of life, including development, was then little understood. Today's unparalleled burst in scientific and technological creativity has given new options and opportunities to the world economic system. Central to this process is a series (...)
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  36. Darwin’s principles of divergence and natural selection: Why Fodor was almost right.Robert J. Richards - 2012 - Studies in History and Philosophy of Science Part C: Studies in History and Philosophy of Biological and Biomedical Sciences 43 (1):256-268.
    In a series of articles and in a recent book, What Darwin Got Wrong, Jerry Fodor has objected to Darwin’s principle of natural selection on the grounds that it assumes nature has intentions.1 Despite the near universal rejection of Fodor’s argument by biologists and philosophers of biology (myself included),2 I now believe he was almost right. I will show this through a historical examination of a principle that Darwin thought as important as natural selection, his principle of divergence. (...)
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  37. Tarski hierarchies.Volker Halbach - 1995 - Erkenntnis 43 (3):339 - 367.
    The general notions of object- and metalanguage are discussed and as a special case of this relation an arbitrary first order language with an infinite model is expanded by a predicate symbol T0 which is interpreted as truth predicate for . Then the expanded language is again augmented by a new truth predicate T1 for the whole language plus T0. This process is iterated into the transfinite to obtain the Tarskian hierarchy of languages. It is shown that there are (...)
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  38.  11
    Selective reading of 1 Corinthians 14:26–40 resulting in the marginalisation of women.Kelebogile T. Resane - 2024 - HTS Theological Studies 80 (3):7.
    The aim of this paper is to point out a hermeneutic gap in Assemblies of God – Back to God’s order of service where 1 Corinthians 14:26–32 is read, eschewing verses 33–38. It points out the Assemblies of God’s perception of women’s ordination into the ministry, where women are allowed to participate in public worship but are not allowed to take up the pastoral leadership of the local assembly. The research problem is the hermeneutic gap behind refusal to ordain women (...)
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  39.  17
    Psychology of mysticism: Toward a layered hierarchy model.Zhuo Job Chen - 2024 - Archive for the Psychology of Religion 46 (3):286-298.
    The studies of mysticism have traditionally emphasized a common core centered around experiences of ego dissolution and unity. However, this focus on a central set of experiences tends to downplay the non-central aspects, resulting in a limited understanding that may not encompass many other types of extraordinary experiences. This article proposes a layered hierarchy model of mysticism, which reverts to the fundamental definition of mysticism and resonates with the Jamesian characteristics of mysticism as noetic and ineffable. Consequently, an extended (...)
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  40.  32
    The aims of expanded universal carrier screening: Autonomy, prevention, and responsible parenthood.Sanne van der Hout, Wybo Dondorp & Guido de Wert - 2019 - Bioethics 33 (5):568-576.
    Expanded universal carrier screening (EUCS) entails a population‐wide screening offer for multiple disease‐causing mutations simultaneously. Although there is much debate about the conditions under which EUCS can responsibly be introduced, there seems to be little discussion about its aim: providing carrier couples with options for autonomous reproductive choice. While this links in with current accounts of the aim of foetal anomaly screening, it is different from how the aim of ancestry‐based carrier screening has traditionally been understood: reducing the disease burden (...)
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  41.  26
    The aims of expanded universal carrier screening: Autonomy, prevention, and responsible parenthood.Sanne Hout, Wybo Dondorp & Guido de Wert - 2019 - Bioethics 33 (5):568-576.
    Expanded universal carrier screening (EUCS) entails a population‐wide screening offer for multiple disease‐causing mutations simultaneously. Although there is much debate about the conditions under which EUCS can responsibly be introduced, there seems to be little discussion about its aim: providing carrier couples with options for autonomous reproductive choice. While this links in with current accounts of the aim of foetal anomaly screening, it is different from how the aim of ancestry‐based carrier screening has traditionally been understood: reducing the disease burden (...)
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  42.  56
    On expandability of models of peano arithmetic to models of the alternative set theory.Athanassios Tzouvaras - 1992 - Journal of Symbolic Logic 57 (2):452-460.
    We give a sufficient condition for a countable model M of PA to be expandable to an ω-model of AST with absolute Ω-orderings. The condition is in terms of saturation schemes or, equivalently, in terms of the ability of the model to code sequences which have some kind of definition in (M, ω). We also show that a weaker scheme of saturation leads to the existence of wellorderings of the model with nice properties. Finally, we answer affirmatively the question of (...)
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  43.  23
    Structural characteristics of two highly selective opioid peptides.Richard J. Knapp, Henry I. Yamamura, Wieslaw Kazmierski & Victor J. Hruby - 1989 - Bioessays 10 (2-3):58-61.
    The demonstration of opioid receptors by radioligand binding and the discovery of their endogenous peptide ligands has provided a new class of compounds that can be used for the development of novel opioids. The number of potential receptor targets for such opioids has been expanded by the identification of multiple opioid receptor types The development of highly selective opioid peptides using the principles of conformational restriction permits the analysis of the structure‐activity requirements of each receptor type, and is facilitating the (...)
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  44. Expanding the notion of mechanism to further understanding of biopsychosocial disorders? Depression and medically-unexplained pain as cases in point.Jan Pieter Konsman - 2024 - Studies in History and Philosophy of Science Part A 103 (C):123-136.
    Evidence-Based Medicine has little consideration for mechanisms and philosophers of science and medicine have recently made pleas to increase the place of mechanisms in the medical evidence hierarchy. However, in this debate the notions of mechanisms seem to be limited to 'mechanistic processes' and 'complex-systems mechanisms,' understood as 'componential causal systems'. I believe that this will not do full justice to how mechanisms are used in biological, psychological and social sciences and, consequently, in a more biopsychosocial approach to medicine. (...)
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  45.  42
    Moving up the hierarchy: A hypothesis on the evolution of a genetic sex determination pathway.Adam S. Wilkins - 1995 - Bioessays 17 (1):71-77.
    A hypothesis on the evolutionary origin of the genetic pathway of sex determination in the nematode Caenorhabditis elegans is presented here. It is suggested that the pathway arose in steps, driven by frequency‐dependent selection for the minority sex at each step, and involving the sequential acquisition of dominant negative, neomorphic genetic switches, each one reversing the action of the previous one. A central implication is that the genetic pathway evolved in reverse order from the final step in the (...) up to the first. The possible applicability of the model to the other well‐characterized sex determination pathway, that of Drosophila melanogaster, and to sex determination in mammals, is discussed, along with some potential implications for pathway evolution in general. Finally, the specific molecular and population genetic questions that the model raises are described and some tests are proposed. (shrink)
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  46.  38
    Use of Analytic Hierarchy Process (AHP) to Identify Material and Relevant CSR Performance Indicators.Marta de la Cuesta, Juan Diego Paredes & Eva Pardo - 2011 - Proceedings of the International Association for Business and Society 22:479-488.
    This study focuses on the application of multicriteria decision-making techniques, specifically the analytic hierarchy process (AHP), to identify corporate socialresponsibility information which both companies and stakeholders consider relevant and material. This work explains how the AHP methodology was applied in the selection of material indicators in corporate social responsibility reporting, the interpretation of these indicators and their relative importance. The results of this study are summarized in 60 indicators distributed in four areas: environment, economy, corporate governance and social. (...)
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  47. Expanding Expertise: Investigating a Musician’s Experience of Music Performance.Andrew Geeves, Doris Mcllwain, John Sutton & Wayne Christensen - 2010 - ASCS09: Proceedings of the 9th Conference of the Australasian Society for Cognitive Science:106-113.
    Seeking to expand on previous theories, this paper explores the AIR (Applying Intelligence to the Reflexes) approach to expert performance previously outlined by Geeves, Christensen, Sutton and McIlwain (2008). Data gathered from a semi-structured interview investigating the performance experience of Jeremy Kelshaw (JK), a professional musician, is explored. Although JK’s experience of music performance contains inherently uncertain elements, his phenomenological description of an ideal performance is tied to notions of vibe, connection and environment. The dynamic nature of music performance advocated (...)
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  48.  64
    Selective Patronage and Social Justice: Local Food Consumer Campaigns in Historical Context.C. Clare Hinrichs & Patricia Allen - 2008 - Journal of Agricultural and Environmental Ethics 21 (4):329-352.
    In the early 2000s, the development of local food systems in advanced industrial countries has expanded beyond creation and support of farmers’ markets and community supported agriculture farms and projects to include targeted Buy Local Food campaigns. Non-governmental groups in many U.S. places and regions have launched such campaigns with the intent of motivating and directing consumers toward more local food purchasing in general. This article examines the current manifestations and possibilities for social justice concerns in Buy Local Food campaigns, (...)
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  49.  61
    Implicational (semilinear) logics I: a new hierarchy[REVIEW]Petr Cintula & Carles Noguera - 2010 - Archive for Mathematical Logic 49 (4):417-446.
    In abstract algebraic logic, the general study of propositional non-classical logics has been traditionally based on the abstraction of the Lindenbaum-Tarski process. In this process one considers the Leibniz relation of indiscernible formulae. Such approach has resulted in a classification of logics partly based on generalizations of equivalence connectives: the Leibniz hierarchy. This paper performs an analogous abstract study of non-classical logics based on the kind of generalized implication connectives they possess. It yields a new classification of logics (...) Leibniz hierarchy: the hierarchy of implicational logics. In this framework the notion of implicational semilinear logic can be naturally introduced as a property of the implication, namely a logic L is an implicational semilinear logic iff it has an implication such that L is complete w.r.t. the matrices where the implication induces a linear order, a property which is typically satisfied by well-known systems of fuzzy logic. The hierarchy of implicational logics is then restricted to the semilinear case obtaining a classification of implicational semilinear logics that encompasses almost all the known examples of fuzzy logics and suggests new directions for research in the field. (shrink)
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  50. Group Selection, Pluralism, and the Evolution of Altruism. [REVIEW]Peter Godfrey-Smith - 2002 - Philosophy and Phenomenological Research 65 (3):685-691.
    One version of pluralism was defended in a well-known paper by Sterelny and Kitcher. In this sense, pluralism is the view that any given selective process can be described at a variety of different levels in the biological hierarchy. On Sterelny and Kitcher’s view, one can explain giraffe necks in terms of competition among longer-necked and shorter-necked giraffes, and one can also explain them in terms of competition among the genes that lead to these differences in neck size. Although (...)
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