Understanding Contemporary Genomics

Perspectives on Science 12 (3):320-338 (2004)
  Copy   BIBTEX

Abstract

Recent molecular biology has seen the development of genomics as a successor to traditional genetics. This paper offers an overview of the structure, epistemology, and history of contemporary genomics. A particular focus is on the question to what extent the genome contains, or is composed of, anything that corresponds to traditional conceptions of genes. It is concluded that the only interpretation of genes that has much contemporary scientific relevance is what is described as the "developmental defect" gene concept. However, developmental defect genes typically only correspond to general areas of the genome and not to precise chemical structures . The parts of the genome to be identified for an account of the processes of normal development are highly diverse, little correlated with traditional genes, and act in ways that are highly dependent on the cellular and higher level environment. Despite its historical development out of genetics, genomics represents a radically different kind of scientific project

Other Versions

No versions found

Links

PhilArchive



    Upload a copy of this work     Papers currently archived: 101,247

External links

Setup an account with your affiliations in order to access resources via your University's proxy server

Through your library

Similar books and articles

Hybrid Vigour? Genes, Genomics, and History.Roberta Bivins - 2008 - Genomics, Society and Policy 4 (1):1-11.
Gene Concepts.Hans-Jörg Rheinberger & Staffan Müller-Wille - 2008 - In Sahorta Sarkar & Anya Plutynski (eds.), Companion to the Philosophy of Biology. Blackwell. pp. 3–21.
Online analysis of development.Peter D. Vize - 2001 - Bioessays 23 (6):549-554.
Reconstructing the concept of homology for genomics.Catherine Kendig - 2001 - Pittsburgh/London Colloquium on Philosophy of Biology and Neuroscience, University of London. Online at PhilSci Archive.
"Life" shaped by genes that depend on their surrounds.Paul Gottlob Layer - 2011 - Annals of the History and Philosophy of Biology 16:153-170.
Making Sense of Genes.Kostas Kampourakis - 2017 - Cambridge, UK: Cambridge University Press.

Analytics

Added to PP
2009-01-28

Downloads
122 (#177,703)

6 months
15 (#205,076)

Historical graph of downloads
How can I increase my downloads?

Author's Profile

John Dupre
University of Exeter

References found in this work

The methodology of scientific research programmes.Imre Lakatos - 1978 - New York: Cambridge University Press.
Philosophy of biological science.David L. Hull - 1974 - Englewood Cliffs, N.J.,: Prentice-Hall.
What Genes Can't Do.Lenny Moss - 2003 - MIT Press.
Genes made molecular.C. Kenneth Waters - 1994 - Philosophy of Science 61 (2):163-185.

View all 6 references / Add more references