Results for 'Vaxtang Erkʻomaišvili'

46 found
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  1. Adamiani, tʻavisupʻleba, ideologia.Vaxtang Erkʻomaišvili - 2002 - Tʻbilisi: Tʻbilisis universitetis gamomcʻemloba.
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  2.  19
    Health, Rights and Dignity: Philosophical Reflections on an Alleged Human Right.Christian Erk - 2011 - De Gruyter.
    The idea that there is such a thing as a human right to health has become pervasive. It has not only been acknowledged by a variety of international law documents and thus entered the political realm but is also defended in academic circles. Yet, despite its prominence the human right to health remains something of a mystery - especially with respect to its philosophical underpinnings. Addressing this unfortunate and intellectually dangerous insufficiency, this book critically assesses the stipulation that health is (...)
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  3.  9
    Bibliographie.Christian Erk - 2015 - In Rationierung Im Gesundheitswesen: Eine Wirtschafts- Und Sozialethische Analyse der Rationierung Nach Selbstverschulden. De Gruyter. pp. 374-409.
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  4. Felsefe ve yaşam üzeri̇ne.Hatice Nur Erkızan - 2006 - In Mustafa Günay & Arslan Kaynardağ, Arslan Kaynardağ'a armağan: Türkiye'de felsefenin kurumsallaşması. İzmir [Turkey]: İlya. pp. 246.
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  5.  12
    VII. Ist Rationierung nach Gesundheitsverhalten moralisch zulässig?Christian Erk - 2015 - In Rationierung Im Gesundheitswesen: Eine Wirtschafts- Und Sozialethische Analyse der Rationierung Nach Selbstverschulden. De Gruyter. pp. 275-287.
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  6.  11
    Literaturverzeichnis: Abkürzungsschlüssel zu abgekürzt zitierten Werken.Christian Erk - 2015 - In Rationierung Im Gesundheitswesen: Eine Wirtschafts- Und Sozialethische Analyse der Rationierung Nach Selbstverschulden. De Gruyter. pp. 371-373.
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  7.  10
    Namensregister.Christian Erk - 2015 - In Rationierung Im Gesundheitswesen: Eine Wirtschafts- Und Sozialethische Analyse der Rationierung Nach Selbstverschulden. De Gruyter. pp. 410-415.
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  8.  8
    Türkiye felsefe yazıları: yaşamın anlam olanakları üzerine: özne, bilgi, kültür.Hatice Nur Erkızan - 2013 - Bursa: Sentez Yayıncılık.
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  9.  10
    Nieuw structuralisme en institutionele verandering: centralisatie en decentralisatie in acht federale staten.Jan Erk & Edward Koning - 2010 - Res Publica 52 (3):405-407.
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  10.  13
    V. Personalität: Was und wer ist eine Person?Christian Erk - 2015 - In Rationierung Im Gesundheitswesen: Eine Wirtschafts- Und Sozialethische Analyse der Rationierung Nach Selbstverschulden. De Gruyter. pp. 121-204.
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  11.  14
    VIII. Schlussgedanken: Von der Zuschreibung retrospektiver zur Stärkung prospektiver Verantwortung.Christian Erk - 2015 - In Rationierung Im Gesundheitswesen: Eine Wirtschafts- Und Sozialethische Analyse der Rationierung Nach Selbstverschulden. De Gruyter. pp. 288-370.
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  12.  14
    Abbildungsverzeichnis.Christian Erk - 2015 - In Rationierung Im Gesundheitswesen: Eine Wirtschafts- Und Sozialethische Analyse der Rationierung Nach Selbstverschulden. De Gruyter.
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  13. Can emotions be dissociated from cognition?S. Erk & H. Walter - 2000 - Consciousness and Cognition 9 (2):S53 - S54.
  14.  8
    Der Bedeutungswandel einiger philosophischer Begriffe im Taoismus.Eduard Erkes - 1953 - Deutsche Zeitschrift für Philosophie 1 (2).
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  15.  16
    I. Einleitung: Sinn, Ziel und Aufbau dieser Arbeit.Christian Erk - 2015 - In Rationierung Im Gesundheitswesen: Eine Wirtschafts- Und Sozialethische Analyse der Rationierung Nach Selbstverschulden. De Gruyter. pp. 1-6.
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  16.  14
    IV. Moralische Pflichten und Rechte.Christian Erk - 2015 - In Rationierung Im Gesundheitswesen: Eine Wirtschafts- Und Sozialethische Analyse der Rationierung Nach Selbstverschulden. De Gruyter. pp. 88-120.
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  17.  15
    II. Rationierung als Mittel zur Bekämpfung des chronischen Finanzierungsdefizits unserer Gesundheitswesen.Christian Erk - 2015 - In Rationierung Im Gesundheitswesen: Eine Wirtschafts- Und Sozialethische Analyse der Rationierung Nach Selbstverschulden. De Gruyter. pp. 7-59.
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  18.  17
    III. Verantwortung.Christian Erk - 2015 - In Rationierung Im Gesundheitswesen: Eine Wirtschafts- Und Sozialethische Analyse der Rationierung Nach Selbstverschulden. De Gruyter. pp. 60-87.
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  19.  17
    Rationierung Im Gesundheitswesen: Eine Wirtschafts- Und Sozialethische Analyse der Rationierung Nach Selbstverschulden.Christian Erk - 2015 - De Gruyter.
    This work explores a controversial strategy for dealing with the chronic financial deficits in our health care system namely, rationing based on the criterion of personal responsibility. It argues that while rationing by personal responsibility is basically morally permissible, it is only possible in a very limited number of instances. For this reason, the use of this rationing criterion should be rejected.".
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  20.  17
    VI. Die moralischen Pflichten und Rechte der zu einem Gesundheitswesen zusammengeschlossenen Personen.Christian Erk - 2015 - In Rationierung Im Gesundheitswesen: Eine Wirtschafts- Und Sozialethische Analyse der Rationierung Nach Selbstverschulden. De Gruyter. pp. 205-274.
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  21.  75
    The heart of death. Re-animating the debate on brain death and transplantation.Christian Erk - 2014 - Ethik in der Medizin 26 (2):121-135.
    Der vorliegende Artikel plädiert dafür, die meist auf die Aspekte Todesdefinition, -kriterium und -feststellung fokussierte Diskussion über die moralische (Un-)Zulässigkeit der Spende und Transplantation vitaler Organe aufzubrechen und beim Nachdenken darüber das zum Ausgangspunkt der Überlegungen zu machen, was mit dem Tod eigentlich verloren geht, nämlich das Leben. Nach einer Antwort auf die Frage „Was ist Leben?“ suchend wird hierbei aufgezeigt, dass Leben nicht auf das Vorhandensein gewisser beobachtbarer physiologischer Größen reduzierbar ist, sondern in seinem wesentlichen Kern nur mit den (...)
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  22.  8
    Abkürzungsverzeichnis.Christian Erk - 2015 - In Rationierung Im Gesundheitswesen: Eine Wirtschafts- Und Sozialethische Analyse der Rationierung Nach Selbstverschulden. De Gruyter.
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  23.  12
    Der Bedeutungswandel einiger philosophischer Begriffe im Taoismus.Eduard Erkes - 1953 - Deutsche Zeitschrift für Philosophie 1 (1):327.
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  24.  12
    Sachregister.Christian Erk - 2015 - In Rationierung Im Gesundheitswesen: Eine Wirtschafts- Und Sozialethische Analyse der Rationierung Nach Selbstverschulden. De Gruyter. pp. 416-418.
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  25.  15
    Türkçe Akademik Söylemde Edilgen Sözceler.Zeynep Erk Emeksi̇z - 2015 - Journal of Turkish Studies 10 (Volume 10 Issue 8):1025-1025.
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  26.  28
    The temporal dynamics of resilience: Neural recovery as a biomarker.Henrik Walter, Susanne Erk & Ilya M. Veer - 2015 - Behavioral and Brain Sciences 38.
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  27.  8
    Adamiani, goni, ġirebuleba.Akaki Bregaże, G. Pʻacʻacʻia & D. Kʻerkʻaże (eds.) - 1991 - Tʻbilisi: "Mecʻniereba".
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  28.  21
    Neuroscientific and Genetic Evidence in Criminal Cases: A Double-Edged Sword in Germany but Not in the United States?Daniela Guillen Gonzalez, Merlin Bittlinger, Susanne Erk & Sabine Müller - 2019 - Frontiers in Psychology 10.
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  29.  12
    Anlama ve yorum: Doğan Özlem armağan kitabı.A. Kadir Çüçen, Hatice Nur Erkızan & Güçlü Ateşoğlu (eds.) - 2004 - Sirkeci, İstanbul: İnkılap.
    Özlem, Doğan; philosophy; biography; Turkey.
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  30.  44
    The Ras‐ERK pathway: Understanding site‐specific signaling provides hope of new anti‐tumor therapies.Fernando Calvo, Lorena Agudo-Ibáñez & Piero Crespo - 2010 - Bioessays 32 (5):412-421.
    Recent discoveries have suggested the concept that intracellular signals are the sum of multiple, site‐specified subsignals, rather than single, homogeneous entities. In the context of cancer, searching for compounds that selectively block subsignals essential for tumor progression, but not those regulating “house‐keeping” functions, could help in producing drugs with reduced side effects compared to compounds that block signaling completely. The Ras‐ERK pathway has become a paradigm of how space can differentially shape signaling. Today, we know that Ras proteins are found (...)
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  31.  36
    A novel target for Huntington's disease: ERK at the crossroads of signaling.László Bodai & J. Lawrence Marsh - 2012 - Bioessays 34 (2):142-148.
    Activating the ERK pathway (extracellular signal‐regulated kinase pathway) has proven beneficial in several models of Huntington's disease (HD), and drugs that are protective in HD models have recently been found to activate ERK. Thus, the ERK cascade may be a potential target for therapeutic intervention in this currently untreatable disorder. HD is caused by an expanded polyglutamine repeat in the huntingtin (Htt) protein that actuates a diverse set of pathogenic mechanisms. In response to mutant Htt, ERK is activated and directs (...)
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  32.  28
    Chronic activation of ERK and neurodegenerative diseases.Luca Colucci-D'Amato, Carla Perrone-Capano & Umberto di Porzio - 2003 - Bioessays 25 (11):1085-1095.
    The extracellular‐signal regulated kinases 1/2 (ERK or ERKs) are involved in the regulation of important neuronal functions, including neuronal plasticity in normal and pathological conditions. We present findings that support the notion that the kinetics and localization of ERK are intrinsically linked, in that the duration of ERK activation dictates its subcellular compartmentalization and/or trafficking. The latter, in turn, dictates whether ERK‐expressing cells would enter a program of cell death, survival or differentiation. We summarize experimental data showing that chronic activation (...)
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  33.  13
    erkes's and LaRue's Outline of a Study of the Self. [REVIEW]H. L. Hollingworth - 1914 - Journal of Philosophy 11 (13):361.
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  34.  13
    Fizikanin tarixinä dair oçerk.Märyäm H. Seyidbäyli - 2018 - Bakı: Elm. Edited by Gülsura Mehdiyeva & Aysel Bädälova.
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  35.  23
    Lysine methylation in cancer: SMYD3‐MAP3K2 teaches us new lessons in the Ras‐ERK pathway.Paula Colón-Bolea & Piero Crespo - 2014 - Bioessays 36 (12):1162-1169.
    Lysine methylation has been traditionally associated with histones and epigenetics. Recently, lysine methyltransferases and demethylases – which are involved in methylation of non‐histone substrates – have been frequently found deregulated in human tumours. In this realm, a new discovery has unveiled the methyltransferase SMYD3 as an enhancer of Ras‐driven cancer. SMYD3 is up‐regulated in different types of tumours. SMYD3‐mediated methylation of MAP3K2 increases mutant K‐Ras‐induced activation of ERK1/2. Methylation of MAP3K2 prevents it from binding to the phosphatase PP2A, thereby impeding (...)
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  36.  18
    The Ethics of Killing: Life, Death, and Human Nature by Christian Erk.Bridget Bagileo Smith - 2022 - The National Catholic Bioethics Quarterly 22 (4):788-790.
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  37.  59
    Walter Mohr: Waldes von seiner Berufung bis zu seinem Tode, Verlag Ferdinand Berger & Söhne, Horn/Niederösterreich o. J. (1971), 75 pp. Waldenser, Geschichte und Gegenwart, hrsg. v. Wolfgang Erk, Verlag Otto Lembeck, Frankfurt 1971, 263 pp. [REVIEW]Hans-Joachim Schoeps - 1972 - Zeitschrift für Religions- Und Geistesgeschichte 24 (2):177-177.
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  38.  8
    Gestaltungen des Entwicklungsgedankens.Kurt Breysig - 1940 - Berlin,: W. de Gruyter & Co..
    BREYSIG: SEIN U. ERK. GESCHICHTL. DINGE BD. 3.
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  39.  19
    Protein kinase cascades activated by stress and inflammatory cytokines.John M. Kyriakis & Joseph Avruch - 1996 - Bioessays 18 (7):567-577.
    Signal transduction pathways constructed around a core module of three consecutive protein kinases, the most distal being a member of the extracellular signal‐regulated kinase (ERK) family, are ubiquitous among eukaryotes. Recent work has defined two cascades activated preferentially by the inflammatory cytokines TNF‐α and IL‐1‐β, as well as by a wide variety of cellular stresses such as UV and ionizing radiation, hyperosmolarity, heat stress, oxidative stress, etc. One pathway converges on the ERK subfamily known as the ‘stress activated’ protein kinases (...)
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  40.  25
    Getting a first clue about SPRED functions.Karin Bundschu, Ulrich Walter & Kai Schuh - 2007 - Bioessays 29 (9):897-907.
    Spreds form a new protein family with an N‐terminal Enabled/VASP homology 1 domain (EVH1), a central c‐Kit binding domain (KBD) and a C‐terminal Sprouty‐related domain (SPR). They are able to inhibit the Ras–ERK signalling pathway after various mitogenic stimulations. In mice, Spred proteins are identified as regulators of bone morphogenesis, hematopoietic processes, allergen‐induced airway eosinophilia and hyperresponsiveness. They inhibit cell motility and metastasis and have a high potential as tumor markers and suppressors of carcinogenesis. Moreover, in vertebrates, XtSpreds help together (...)
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  41.  12
    The integrated stress response in the induction of mutant KRAS lung carcinogenesis: Mechanistic insights and therapeutic implications.Antonis E. Koromilas - 2022 - Bioessays 44 (8):2200026.
    The integrated stress response (ISR) is a key determinant of tumorigenesis in response to oncogenic forms of stress like genotoxic, proteotoxic and metabolic stress. ISR relies on the phosphorylation of the translation initiation factor eIF2 to promote the translational and transcriptional reprogramming of gene expression in stressed cells. While ISR promotes tumor survival under stress, its hyperactivation above a level of tolerance can also cause tumor death. The tumorigenic function of ISR has been recently demonstrated for lung adenocarcinomas (LUAD) with (...)
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  42.  51
    From songs to synapses: Molecular mechanisms of birdsong memory.Sanne Moorman, Claudio V. Mello & Johan J. Bolhuis - 2011 - Bioessays 33 (5):377-385.
    There are remarkable behavioral, neural, and genetic similarities between the way songbirds learn to sing and human infants learn to speak. Furthermore, the brain regions involved in birdsong learning, perception, and production have been identified and characterized in detail. In particular, the caudal medial nidopallium (the avian analog of the mammalian auditory‐association cortex) has been found to contain the neural substrate of auditory memory, paving the way for analyses of the underlying molecular mechanisms. Recently, the zebra finch genome was sequenced, (...)
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  43.  36
    LAT: a T lymphocyte adapter protein that couples the antigen receptor to downstream signaling pathways.Connie L. Sommers, Lawrence E. Samelson & Paul E. Love - 2004 - Bioessays 26 (1):61-67.
    Adapter molecules in a variety of signal transduction systems link receptors to a limited number of commonly used downstream signaling pathways. During T‐cell development and mature T‐cell effector function, a multichain receptor (the pre‐T‐cell antigen receptor or the T‐cell antigen receptor) activates several protein tyrosine kinases. Receptor and kinase activation is linked to distal signaling pathways (PLC‐γ1 activation, Ca2+ influx, PKC activation and Ras/Erk activation) via the adapter protein LAT (Linker for Activation of T cells). Structure/function studies of LAT including (...)
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  44.  18
    Light and Metaphor in Plotinus and St. Thomas Aquinas.Kevin Corrigan - 1993 - The Thomist 57 (2):187-199.
    In lieu of an abstract, here is a brief excerpt of the content:LIGHT AND METAPHOR IN PLOTINUS AND ST. THOMAS AQUINAS KEVIN CORRIGAN St. Thomas More College University of Saskatchewan Saskatoon, Saskatchewan I HAVE TWO CONCERNS in this paper. The first is a broad concern, related to the nature of metaphor, which stems from the destructionist or deconstructionist tendencies in some contemporary phenomenology or phenomenological existentialism. According to these views, the logocentric emphasis of the Western tradition must be shown for (...)
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  45. Der ṿeg tsu a gliḳlikh lebn: baarbeṭ fun di serye shiʻurim "Menuḥes ha-nefesh"..Yitsḥoḳ Elozer Mosḳoṿiṭsh - 2017 - Bruḳlin, N.Y.: Mekhon Daʻat u-tevunah.
    1. Ḳlorshṭeln dem emes̀'n Toyrehdign 'ṿeg tsu a gliḳlikh leb' durkh arbeṭn af di mides̀ on darfn nutsn profesyonale ṭerapi. Ṿen darfn yo nutsn ṭerapi un ṿos iz der rikhṭiger tsugang dertsu. A breyṭe erḳlerung iber di yesoydes̀ fun Idishḳeyṭ.
     
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  46.  7
    Integrating the MAP kinase signal into the G1 phase cell cycle machinery.Kristin Roovers & Richard K. Assoian - 2000 - Bioessays 22 (9):818-826.
    Growth factors and the extracellular matrix provide the environmental cues that control the proliferation of most cell types. The binding of growth factors and matrix proteins to receptor tyrosine kinases and integrins, respectively, regulates several cytoplasmic signal transduction cascades, among which activation of the mitogen-activated protein kinase cascade, ras → Raf → MEK → ERK, is perhaps the best characterized. Curiously, ERK activation has been associated with both stimulation and inhibition of cell proliferation. In this review, we summarize recent studies (...)
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