The concepts of hierarchical organization, genetic determinism and biological specificity have played a crucial role in biology as a modern experimental science since its beginnings in the nineteenth century. The idea of genetic information and genetic determination was at the basis of molecular biology that developed in the 1940s with macromolecules, viruses and prokaryotes as major objects of research often labelled “reductionist”. However, the concepts have been marginalized or rejected in some of the research that in the late 1960s began (...) to focus additionally on the molecularization of complex biological structures and functions using systems approaches. This paper challenges the view that ‘molecular reductionism’ has been successfully replaced by holism and a focus on the collective behaviour of cellular entities. It argues instead that there are more fertile replacements for molecular ‘reductionism’, in which genomics, embryology, biochemistry, and computer science intertwine and result in research that is as exact and causally predictive as earlier molecular biology. (shrink)

The concepts of hierarchical organization, genetic determinism and biological specificity have played a crucial role in biology as a modern experimental science since its beginnings in the nineteenth century. The idea of genetic information and genetic determination was at the basis of molecular biology that developed in the 1940s with macromolecules, viruses and prokaryotes as major objects of research often labelled “reductionist”. However, the concepts have been marginalized or rejected in some of the research that in the late 1960s began (...) to focus additionally on the molecularization of complex biological structures and functions using systems approaches. This paper challenges the view that ‘molecular reductionism’ has been successfully replaced by holism and a focus on the collective behaviour of cellular entities. It argues instead that there are more fertile replacements for molecular ‘reductionism’, in which genomics, embryology, biochemistry, and computer science intertwine and result in research that is as exact and causally predictive as earlier molecular biology. (shrink)

Understanding the relationship between adult fish populations (the "stock") and the number of new fish entering the population (the "recruits") is essential for effective fisheries management. Traditionally, this relationship is represented by a stock-recruitment (SR) function, which is a simplified mathematical model that directly links stock size to recruitment. However, fish populations pass through several life stages, each stage influenced by unique population dynamic factors. Current SR functions often overlook these complexities, assuming that recruitment depends solely on the adult population (...) size. In this study, we use a multi-stage, age-structured discrete-time population dynamic model that accounts for all life stages and the transitions between them. We demonstrate that, in general, a closed-form, univariate SR function may not accurately represent the recruitment process when these life stages are considered. Instead, we identify specific mathematical conditions under which a SR function is equivalent to our multi-stage model. Our findings suggest a re-evaluation of conventional SR models, advocating for multi-stage approaches to support fisheries management decisions. (shrink)

ABSTRACTThis study investigated age differences in empathic accuracy, the ability to correctly perceive others’ emotions, in a sample of 151 boys and men from three age groups: adolescents, young adults, and middle-aged adults. All participants viewed nine newly developed film clips, each depicting a boy or a man reliving one of three emotions, while talking about an autobiographical memory. Adolescents and middle-aged men were less accurate than young men, and these age differences were associated with parallel age differences in fluid-mechanical (...) abilities. In addition, age differences in vocabulary, one indicator of crystallized-pragmatic intelligence, were associated with age differences in empathic accuracy in adolescent and young, but not middle-aged, men. Within the limitations of cross-sectional data, this study provides evidence for the idea that empathic accuracy is an effortful t... (shrink)

A revised and enlarged version of Biologen unter Hitler, translated by Thomas Dunlap.

Ute Gahlings opens up the professional field of philosophical practice with its various forms of activity such as consolation and life orientation, education and personality development as well as political and social commitment. On the basis of concrete situations in philosophical practice, she traces the complex intersubjective processes phenomenologically. She illuminates the importance of intuition, presence and atmosphere as well as the professional framing of the encounter in the field of tension between proximity and distance. In this multidimensionality, the author (...) is always concerned with core questions of an ethically based anthropology. Therefore, she also deals with professional ethical considerations and develops a code of ethics. (shrink)

Der Ruf des Esels als offenes Klangobjekt in Robert Bressons Film Au hazard Balthazar (F 1966), der die Bild-Montage insistierend stört, wird in diesem Beitrag in den Kontext der Bioakustik gestellt. Am JA des Esels differenzieren sich Geräusche medial so aus, dass die Grenze zwischen Ding und Kreatur durchlässig wird. Bressons Passion erweist sich damit als Experiment, die akustischen Kanäle der Kommunikation als Transformatoren von Lebewesen, Räumen und jener Übertragung wahrzunehmen, die kybernetisch informierten Tierforschern Sprache heißt. The paper presents the (...) donkey's bray in Robert Bresson's film (F 1966) that disturbs the montage insistently as an open sound object and puts it in the context of bioacoustics. The donkey's hee-haw diversifies noise in such a way that the borderline between object and creature becomes permeable. Bresson's passion proves to be an experiment to perceive the acoustic channels of communication as transformers of animals, spaces and that kind of transmission that researchers informed by cybernetics call »language«. (shrink)

This paper gives an overview about the transmission of Greek popular philosophical writings in Ethiopian literature. Information about the historical and religious background in Ethiopia until the 13th century is very scanty, and also the conditions of transmission of Greek philosophy in monastic circles are poorly attested. An analysis of the ambivalent attitude towards Greek philosophy and secular education in Syriac and Coptic monasticism could shed some light on intellectual preconditions in Ethiopian monasteries, because they were significantly influenced by these (...) circles. The manuscript tradition of relevant writings gives us an additional clue which themes and works were preferred among monks in Egypt. Manuscripts containing popular philosophy circulated in the existent network of monasteries in Egypt and Ethiopia, and an increased interest, especially in the 15th/16th centuries, in these writings give rise to their translation from Arabic into Ethiopic. (shrink)

In the recent decade the perspectives of historical epistemology have turned economic practices into a novel object of study: the focus lies on how discourses, techniques of measurement and valuation produce economic facts.1 The research on the historical epistemologies of economic facts belongs to a broader scholarly endeavor that takes place in cultural anthropology, social theory, literary studies, political theory and history. This interdisciplinary work brings to light how deeply economic issues are constituted by intermingling a set of cultural, political, (...) technical and legal distinctions, which distinguish what counts as properly economic from what does not.2 In this perspective, the very definition of economy becomes a hybrid and contentious affair.The central theoretical question for the historical epistemology and cultural anthropology of economy is currently how to conceptualize the link between epistemic practices and acts of ‘doing the economy’. This special issue on the Historical Episte mology of the Economic pushes us to think about this crucial link. Monika Dommann, Daniel Speich Chassé and Mischa Suter explore different modes of approaching the interlacing of epistemology and economy. These modes can be discussed under the following headings: 1) Pragmatics and Poetologies of Knowledge, 2) Economic Discourses and Epistemic Techniques, 3) Boundaries of Economy. On the basis of the richness of the historical material and the finely grained arguments that these papers bring forth, I will elaborate on the conceptualization of these linkages between epistemology and economy. My discussion culminates in the attempt to clarify an analytical distinction that is freely used in this special issue but that deserves further discussion: the distinction between the economic and the economy as an object of historical epistemology. My question is, does it matter if we write a historical epistemology of the economic or of the economy? What distinction do we wish to make by juxtaposing these two? (shrink)

Petrus Martyr d'Anghiera dealt twice with the ethical discussions concerning the Spanish colonization in America around 1524. A straight reading shows how this sensitive topic was presented with caution and literary skill, thereby mitigating the charge of opportunism that several authors have made.

Le Code civil français, premier code libéral et bourgeois d’Europe, passe, en raison de sa clarté systématique et de sa langue, pour un modèle de législation moderne. En outre, il eut une influence durable parce qu’il est resté en vigueur dans de nombreux pays d’Europe après la fin des conquêtes napoléoniennes. Pourtant, en comparaison avec d’autres codifications européennes et avec le droit coutumier de son temps, le Code français se caractérise, dans le droit conjugal et familial, par des règles particulièrement (...) rigides consolidant la domination masculine. L’article propose une analyse comparée de certains aspects du droit civil qui ont eu et ont encore un impact considérable sur la vie des femmes et sur l’histoire des mouvements féministes. Il se demande pourquoi les Françaises, qui se sont fait entendre plus tôt que d’autres dans leur lutte pour les droits des femmes qu’elles revendiquaient comme des droits humains, ont paradoxalement obtenu la reconnaissance de leur égale citoyenneté relativement tard (en 1944 seulement) par rapport aux autres pays européens. (shrink)

Egoismus wie Genuß scheinen heutzutage zunächst ichbezogen und daher asozial; Erfahren und Erkennen, Genießen und Produzieren stehen sich merkwürdig fern. Eher selten geht - wie für den jungen Karl Marx - der "Anblick eines bunten Luftspringers" entschieden über den eines "ängstlich-zugeknöpften, in sich geduckten Indivi-duums". Genuß und Egoismus können jedoch als verbunden gedacht und so als unverzichtbar erfahren werden für menschlich verfaßte Gemeinschaften. Geschichtlich haben beson-ders die Literatur sowie Teile der Sozial- und Moralphilosophie zu einem solchen Denken Beiträge geleistet. Eine (...) Reihe dieser Konzepte - von Augustinus bis zu neuen Modernetheorien in Lateinamerika, mit dem Schwerpunkt im 18. und 19. Jahrhundert - genauer zu begreifen und zu vergegenwärtigen ist das Ziel des Buches. Sie zeigen: Das Vergnügen, aus eignen Mitteln eine ganze Welt zu bauen, vermag zu den höchsten zu zählen. Welten verlieren an Lebenswert, wenn sie dieses Vergnügen aufs Geistige beschränken oder die Selbstsucht gar hinter Masken und in die entfremdete Existenz zwingen. Der Anspruch, für sich genießend zu produzieren, kommt - allen Dementis der Praxis zum Trotz - aus gesundem Menschenverstand und ist ein Menschenrecht. Die Autoren des Buches sind Romanisten und Komparatisten, Philosophiehistoriker, Anglisten und Amerikanisten, sie haben ihre Texte aus Anlaß des 75. Geburtstages des Aufklärungsforschers, Stendhal-Kenners, Literaturtheoretikers und genießenden Egotisten Manfred Naumann, über den einige Beiträge und eine umfassende Bibliographie der Schriften informieren, zur Verfügung gestellt. (shrink)

This article argues that Foucault’s account of the intersection between population, liberal economy, and biopolitics needs to be reconstructed in light of Malthus’ Essay on the Principle of Population. Taking Malthus into account brings to the fore how deeply the question of population is tied to a colonial hierarchy that differentiates between dangerous ‘savage’ and economic ‘civilized’ life. ‘Savage life’ is depicted as a catastrophic form of life, which uses resources in a non-economic way due to its forgetfulness of the (...) future. The article shows how this notion of ‘savage life’ broadens the concept of liberal economic governmentality. Most importantly, it highlights the role of passions and futurity for liberal governmentality. As the discussion of Malthus’ texts demonstrates, the passions of hope and fear assume a crucial role for engendering futurity in the economic subject. As will be shown, while the more ‘savage life’ is considered to be made governable through fear, the more civilized life is supposed to be allured by hope. The article points out the implication of this analysis for Foucault’s notion of biopolitics in relation to liberal economy. (shrink)

Development and homeostasis of the haematopoietic system is dependent upon stem cells that have the unique ability to both self‐renew and to differentiate in all cell lineages of the blood. The crucial decision between haematopoietic stem cell (HSC) self‐renewal and differentiation must be tightly controlled. Ultimately, this choice is regulated by the integration of intrinsic signals together with extrinsic cues provided by an exclusive microenvironment, the so‐called haematopoietic niche. Although the haematopoietic system of vertebrates has been studied extensively for many (...) decades, the specification of the HSC niche and its signals involved are poorly understood. Much of our current knowledge of how niches regulate long‐term maintenance of stem cells is derived from studies on Drosophila germ cells. Now, two recently published studies by Mandal et al.1 and Krezmien et al.2 describe the Drosophila haematopoietic niche and signal transduction pathways that are involved in the maintenance of haematopoietic precursors. Both reports emphasize several features that are important for controlling stem cell behavior and show parallels to both the vertebrate haematopoietic niche as well as the Drosophila germline stem cell niches in ovary and testis. The findings of both papers shed new light on the specific interactions between haematopoietic progenitors and their microenvironment. BioEssays 29:713–716, 2007. © 2007 Wiley Periodicals, Inc. (shrink)

Ephrem's own writings however frequently betray a familiarity with Greek philosophical ideas. This book first introduces Ephrem's intellectual context and his attitude towards learning.

This paper discusses the extent to which governmentality provides a critical visibility of the economy beyond its liberal imaginary. It argues that Foucault’s conceptual and historical understanding of liberal governmentality has two traits that encumber a de-centering of the economy from a Foucauldian perspective. The first obstacle results from a persistent asymmetry of the concept of governmentality as it remains solely geared towards replacing the monolithic account of the state. Governmentality is therefore in danger of rendering the economic invisible instead (...) of advancing an analytics of power appropriate to the specificity of this field. The second impediment relates to how Foucault reads the invisibility of the economy asserted in liberal discourse. While Foucault emphasizes how the “invisible hand” imparts a critical limitation towards the sovereign hubris of total sight, the paper unearths a more complex politics of truth tied to the invisible economy. Drawing on selected historical material, the papers shows that the liberal invisibility of the economy rather functions as a prohibitive barrier towards developing novel and critical visibilities of the economy. A Foucauldian perspective on economy, the paper concludes, benefits from piercing through this double invisibility of the economy. (shrink)

This essay examines dominant notions of reproductive identity in feminist bioethics from a queer-crip perspective by considering the “reproductive situation” in Germany of people who are classified as disabled and people who are classified as queer. I analyze the ways in which such people are excluded from the understandings of reproductive identity that figure prominently in German feminist bioethics, and argue that feminist bioethics in Germany, which has become a well-established part of important bioethical institutions, reflects many, if not most, (...) of the neo-eugenic developments that characterize more recognizably mainstream bioethics. I also show that (German) feminist bioethics (like its more recognizably mainstream counterpart) constitutes the reproductive subject as nondisabled, intelligibly gendered, and heterosexual. (shrink)