ZusammenfassungAktuelle Untersuchungen zum Gene Editing an menschlichen Embryonen zeigen große Erfolge bei der Korrektur vererbbarer Krankheiten und treiben die Grundlagenforschung sowie die Präimplantations-Gendiagnostik enorm voran. Was von Forschungen dieser Art aus ethischer Sicht zu halten ist, ist dagegen weniger eindeutig. Ein Blick auf den aktuellen Diskurs zeigt, dass diese Entwicklungen sehr kontrovers diskutiert werden und eine Einigung darüber, ob sie vorangebracht werden sollen oder nicht, keineswegs in Sicht ist. Zum Zweck der Orientierung und auch besseren Positionierung in der aktuellen Debatte (...) befasst sich die vorliegende Untersuchung zum einen mit der Art des Wissens vom Gene Editing sowie dessen epistemischen Grundlage und zum anderen mit den ethisch-normativen Überzeugungen, an die die Befürworter und Gegner in der ethischen Bewertung des Gene Editing jeweils appellieren. Dabei zeigt sich, dass die Überzeugungen, auf die sich die Befürworter stützen, der speziellen Art dieses Wissens und seiner epistemischen Grundlage stärker Rechnung tragen, während das von den Überzeugungen, auf die sich die Gegner berufen, gerade nicht zu erwarten ist. Diese Einsicht in die Struktur der Debatte erlaubt es, die verschiedenen Argumentationsweisen in Beziehung zu setzen, ihre jeweiligen Perspektiven einzunehmen und auch ihre blinden Flecken aufzudecken. (shrink)

For three centuries, concepts of the state have been animated by one of the most powerful metaphors in politics: the body politic, a claustrophobic and bounded image of sovereignty. Climate change, neoliberalism, mass migration, and other aspects of the late Anthropocene have increasingly revealed the limitations of this metaphor. Just as the human body is not whole and separate from other bodies--comprising microbes, bacteria, water, and radioactive isotopes--Stefanie R. Fishel argues that the body politic of the state exists in (...) dense entanglement with other communities and forms of life. Drawing on insights from continental philosophy, science and technology studies, and international relations theory, this path-breaking book critiques the concept of the body politic on the grounds of its very materiality. Fishel both redefines and extends the metaphor of the body politic and its role in understanding an increasingly posthuman, globalized world politics. By conceiving of bodies and states as lively vessels, living harmoniously with multiplicity and the biosphere, she argues that a radical shift in metaphors can challenge a politics based on fear to open new forms of global political practice and community. Reframing the concept of the body politic to accommodate greater levels of complexity, Fishel suggests, will result in new configurations for the political and social organization necessary to build a world in which the planet's inhabitants do not merely live but actively thrive. (shrink)

When, in 1735, Alexander Gottlieb Baumgarten added a new discipline to the philosophical system, he not only founded modern aesthetics but also contributed to shaping the modern concept of art or 'fine art'. In The Founding of Aesthetics in the German Enlightenment, Stefanie Buchenau offers a rich analysis and reconstruction of the origins of this new discipline in its wider context of German Enlightenment philosophy. Present-day scholars commonly regard Baumgarten's views as an imperfect prefiguration of Kantian and post-Kantian aesthetics, (...) but Buchenau argues that Baumgarten defended a consistent and original project which must be viewed in the context of the modern debate on the art of invention. Her book offers new perspectives on Kantian aesthetics and beauty in art and science. (shrink)

This book offers an innovative defense of Wilfrid Sellar's notion of ideal truth. Sellars adopts two attractive ideas about truth: the pragmatist idea that the concept of truth cannot be understood independently from the norms and practices we find ourselves with and the realist idea that there is one ultimate truth about how the world is. Sellars is thus committed both to an immanent notion of truth and an ideal notion of truth. This book discusses these countervailing tendencies and tries (...) to reconcile them. The author's defense of Sellars's notion of truth minimizes problematic commitments while still being recognizably rooted in Sellars's texts. Additionally, the author defends several innovative claims with respect to Sellars's thinking, for example, about the relative unimportance of his controversial concept of pictorial adequacy and about the neglected significance of considerations concerning context-sensitive expressions in his thought. Wilfrid Sellars on Truth will be of interest to scholars and advanced students working on Wilfrid Sellars, pragmatism, and questions about truth, naturalism, and scientific realism. (shrink)

Name der Zeitschrift: Naharaim Jahrgang: 9 Heft: 1-2 Seiten: 4-24.

The Court of Appeals of Indiana upheld the trial court's judgment and refused to create a new tort for “wrongful prolongation of life” because existing law offers a remedy to those who do not wish to be kept alive through artificial measures. Specifically, the court affirmed the trial court's dismissal in favor of Muncie Medical Investors, LP, the operator of Woodlands Nursing Home since the plaintiffs could have sought relief under I.C. § 16-36-1-8 which provides for court resolution of disputes (...) regarding an individual's treatment at the end of life.In 1992, Rebecca Taylor suffered a stroke that left her paralyzed on her left side and confined to a wheelchair. Taylor executed a living will in late 1993 directing that if she was suffering from a terminal illness with “no reasonable possibility of recovery,’’ then no “extraordinary means” to prolong her life should be used. (shrink)

To investigate the effects of mood on people's end-of-life treatment decisions and their false memories of those decisions, participants took part in two sessions. At Time 1, participants were experimentally induced into positive or negative moods. They decided whether they would want to receive or refuse treatments in a range of hypothetical medical scenarios, such as tube feeding while in a coma. Four weeks later, at Time 2, participants were induced into the same or the opposite mood and made these (...) decisions a second time. They also recalled their previous decisions. Participants in negative moods at Time 2 changed more of their current decisions and falsely remembered more of their previous decisions than participants in positive moods. These findings suggest that people's current moods influence whether they change their treatment decisions; current decisions in turn bias recall of past decisions. (shrink)

Despite their opposite emotional effects, humor and horror are highly similar phenomena. They both can be traced back to (the detection, resolution, and emotional elaboration of) incongruities, understood as semantic violations through unexpected combinations of oppositional information. However, theoretical and experimental comparisons between humor and resolvable incongruities that elicit other emotions than exhilaration have been lacking so far. To gain more insights into the linguistic differences between humor and horror and the cognitive real-time processing of both, a main concern of (...) this book is to discuss the transferability of linguistic humor theories to a systematic horror investigation and directly compare self-paced reading times (SPR), facial actions (FACS), and event-related brain potentials (ERP) of normed minimal quadruplets with frightening and humorous incongruities as well as (in)coherent stimuli. The results suggest that humor and horror share cognitive resources to detect and resolve incongruities. To better distinguish humor from neighboring phenomena, this book refines current humor theories by incorporating humor and horror in a cognitive incongruity processing model. (shrink)

The current use of the term ‘Human Enhancement’ implies that it is a modern, new phenomenon in which, for the first time in history, humans are able to break through their god or nature-given bodily limits thanks to the application of new technologies. The debate about the legitimation of ‘HE’, the selection of methods permitted, and the scope and purpose of these modern enhancement technologies has been dominated by ethical considerations, and has highlighted problems with the definition of the relevant (...) norms. For example, ‘HE’ always presupposes that the current state of the ‘natural human’ or ‘healthy’ body is defined in opposition to an ‘artificial human’ or ‘diseased or disabled’ body, and also desirable technologies and methods are not but should be defined on the basis of objective, universally accepted criteria. All these definitions are, however, linked to socio-cultural norms and ideals, which can vary over time and between cultures. It is therefore impossible to arrive at a universal, durable definition of ‘enhancement’ that can be shared and understood globally, and will remain permanently valid. This discussion note contrasts the terms ‘HE’ and ‘Body Modification’ , and their respective strengths and weaknesses. ‘BM’ is a neutral term that is capable of encompassing every kind of modification, be it cultural, physical, psychological or neurological, is not limited to certain techniques and is not reliant on normative sub-definitions . In the light of this analysis, it is proposed that the term ‘HE’ be replaced with ‘BM’ in order to allow a neutral, unprejudiced discussion to take place. (shrink)

This book provides the first comprehensive account of Hume’s conception of objects in Book I of the Treatise. What, according to Hume, are objects? Ideas? Impressions? Mind-independent objects? All three? None of the above? Through a close textual analysis, I show that Hume thought that objects are imagined ideas. However, I argue that he struggled with two accounts of how and when we imagine such ideas. On the one hand, Hume believed that we always and universally imagine that objects are (...) the causes of our perceptions. On the other hand, he thought that we only imagine such causes when we reach a “philosophical” level of thought. This tension manifests itself in Hume’s account of personal identity; a tension that, I argue, Hume acknowledges in the Appendix to the Treatise. As a result of presenting a detailed account of Hume’s conception of objects, we are forced to accommodate new interpretations of, at least, Hume’s notions of belief, personal identity, justification and causality. (shrink)

Despite decades of research, morphogenesis along the various body axes remains one of the major mysteries in developmental biology. A milestone in the field was the realisation that a set of closely related regulators, called Hox genes, specifies the identity of body segments along the anterior–posterior (AP) axis in most animals. Hox genes have been highly conserved throughout metazoan evolution and code for homeodomain‐containing transcription factors. Thus, they exert their function mainly through activation or repression of downstream genes. However, while (...) much is known about Hox gene structure and molecular function, only a few target genes have been identified and studied in detail. Our knowledge of Hox downstream genes is therefore far from complete and consequently Hox‐controlled morphogenesis is still poorly understood. Genome‐wide approaches have facilitated the identification of large numbers of Hox downstream genes both in Drosophila and vertebrates, and represent a crucial step towards a comprehensive understanding of how Hox proteins drive morphological diversification. In this review, we focus on the role of Hox genes in shaping segmental morphologies along the AP axis in Drosophila, discuss some of the conclusions drawn from analyses of large target gene sets and highlight methods that could be used to gain a more thorough understanding of Hox molecular function. In addition, the mechanisms of Hox target gene regulation are considered with special emphasis on recent findings and their implications for Hox protein specificity in the context of the whole organism. BioEssays 30:965–979, 2008. © 2008 Wiley Periodicals, Inc. (shrink)

El siguiente artículo tiene por objetivo mostrar la mutua correspondencia entre experiencia e historicidad en la obra de Hans-Georg Gadamer. La experiencia es entendida como el movimiento fundamental de la existencia histórica, la que articula las diversas esferas de la acción humana. La experiencia hermenéutica pone de manifiesto que el comprender no puede fundarse en un procedimiento metódico, sino en la forma del existir situado en el mundo. El acto hermenéutico es entendido como un continuo proceso de apropiación, que se (...) realiza mediante el lenguaje, y donde se van actualizando nuevos significados que develan el carácter aconteciente y móvil de la interpretación. Por ello, la historicidad de la comprensión será el principio hermenéutico fundamental que excluye la posibilidad de una conciencia histórica absoluta, a favor de una “conciencia de la repercusión histórica” (wirkungsgeschtliches Bewußtseins). The following article aims at showing the mutual correspondence between experience and historicity in the work of Hans-Georg Gadamer. Experience is understood as the fundamental movement of the historical existence, whichvarious spheres ofhuman action. The hermeneutic experience shows thatnot lie in methodical procedure, but in the way of existence in the world. The hermeneuticis understood as a continuing process that is carried out through language and where new meanings are updated, that reveal mobile characteristics of the interpretation. Therefore, the understanding the hermeneutical principle which excludes possibility ofabsolute consciousness, in favor of a historically-effected consciousness (wirkungsgeschtliches Bewußtseins). (shrink)

Resumo: A proposta desse trabalho é repensar a linguagem, tema central da filosofia contemporânea, não mais como um instrumento do qual o sujeito se apropria e desapropria de acordo com a própria vontade, mas, juntamente com Heidegger, como a própria casa do ser. A função de comunicação é apenas uma das múltiplas possibilidades da linguagem. Com Heidegger é desenvolvida a questão de como a fenomenologia transforma-se em hermenêutica e de como a autocompreensão surge paralela a toda compreensão. A filosofia autêntica (...) é aquela na qual, ao questionar-se sobre algo, o sujeito é inserido na própria questão. A compreensão nunca é impessoal, pois a aletheia perpassa o sujeito que, ao compreender algo, está compreendendo a si mesmo. Palavras-chave: Filosofia. Martin Heidegger. Linguagem. Lógica. Verdade. Metafísica.: The purpose of this paper is to rethink the language, the central theme of contemporary philosophy, not as an instrument to which the subject is appropriate and unappropriate according to their will, but, along with Heidegger, as the house of being. The function of communication is only one of the many possibilities of language. With Heidegger is developed the question of how phenomenology turns to hermeneutics and how the selfunderstanding is parallel to all understanding. The authentic philosophy is that in which is questioned about something and the subject is inserted in the issue. The understanding is never impersonal, therefore Aletheia permeates the subject that by understanding something is to understand yourself. Keywords: Philosophy. Martin Heidegger. Language. Logic. Thuth. Metaphysics. (shrink)

In "Beyond the Myth of the Myth: A Kantian Theory of Non-Conceptual Content", Robert Hanna argues for a very strong kind of non-conceptualism, and claims that this kind of non-conceptualism originally has been developed by Kant. But according to "Kant's Non-Conceptualism, Rogue Objects and the Gap in the B Deduction", Kant's non-conceptualism poses a serious problem for his argument for the objective validity of the categories, namely the problem that there is a gap in the B Deduction. This gap is (...) that the B Deduction goes through only if conceptualism is true, but Kant is a non-conceptualist. In this paper I argue, contrary to what Hanna claims, that there is not a gap in the B Deduction. (shrink)

Response to Don Baxter, Don Garrett and Jennifer Marusic regarding my book Imagined Causes: Hume's Conception of Objects; initially delivered at the 2016 Hume Conference in Sydney, Australia as part of the Author Meets Critics session.

My paper is concerned with the relation between ought-statements and intentions in Wilfrid Sellars’s philosophy. According to an entrenched view in Sellars scholarship, Sellars considers ought-statements as expressions of we-intentions. The aim of my paper is to question this reading and to propose an alternative. According to this alternative reading of Sellars, ought-statements are metalinguistic statements about the implication relations between intentions. I show that the entrenched understanding faces many unacknowledged problems and generates incompatibilities with Sellars’s commitments about intentions. I (...) argue that the alternative account can help to resolve these problems. A second reason in support of the alternative understanding of Sellars is provided by historical considerations. I argue that my alternative account can be discerned in Sellars’s most developed views about intentions and ought-statements. I also discuss problems and questions which the alternative reading itself faces. (shrink)

Stefanie Buchenau | : Johann Georg Sulzer participe d’une tradition allemande et wolffienne qui conjugue réflexion épistémologique et esthétique. L’originalité de Sulzer au sein de cette tradition consiste à développer un nouveau modèle de la connaissance comme contemplation. Selon ce modèle spéculatif qui emprunte des éléments à l’esthétique de Du Bos, la distance et l’extériorité du spectateur par rapport à son objet est loin d’être le réquisit d’une bonne vision. Celle-ci dépend tout au contraire de l’appartenance du spectateur au (...) monde qu’il contemple, de sa réceptivité, de sa sensibilité et de son humanité. Car l’âme ne peut déployer son activité de pensée qu’à condition de s’attacher d’abord à son objet : un tel attachement est la condition de son détachement. La mise en place de ce nouveau modèle spéculatif répond à l’injonction de Mérian qui est de repenser la conscience ou l’aperception à partir d’un sentiment a posteriori. Car « l’oeil ne se voit pas voir », et l’aperception primitive, cet acte par lequel l’esprit se pense, lui échappe. Il éprouve néanmoins des sentiments — de plaisir et de déplaisir — qui le contraignent à faire retour sur lui-même et sur son état d’être affecté ; des sentiments dont Sulzer considère qu’ils ancrent sa connaissance dans la réalité et lui permettent de la rapporter à soi-même. C’est ainsi qu’au fil des mémoires académiques des années 1750 à 1770, Sulzer élabore une nouvelle conception tripartite des facultés, et une distinction entre domaines théorique et pratique qui marquera la philosophie de Kant. Ce débat au sein de l’Académie berlinoise au sujet de la connaissance de soi donne une nouvelle orientation anthropologique à la philosophie allemande de la seconde moitié du xviiie siècle. | : Johann Georg Sulzer belongs to a German and Wolffian tradition that closely associates theory of knowledge and aesthetics. Sulzer’s originality within this tradition consists in introducing a new model of contemplation. This model borrows elements from Du Bos and leads him to revise the traditional paradigms of cognition and self-cognition : more than the spectator’s distance and exteriority to her object, good vision requires her involvement and inclusion into the world she contemplates, that is her receptivity, sensibility and humanity. For her soul cannot unfold its activity unless it is attached to its object. Such attachment is the condition of its detachment. Sulzer elaborates his model of speculation in response to issues recently raised by his colleague Merian within the Berlin academy. Merian had emphasized the necessity to rethink consciousness or apperception on the basis of some posteriori feeling. For “the eye does not see itself seeing” and the primitive apperception, the act of thinking itself, necessarily escapes the soul’s aperception : it nonetheless has feelings — of pleasure and displeasure — which make the soul reflect on itself and its state of affection ; For Sulzer, these feelings are what grounds knowledge in reality and establishes a relation to the self. In his writings from the 1750’ies to the 1770’ies Sulzer develops these insights and elaborates a new division of faculties and of the theoretical vs. practical that will shape Kant’s psychology and philosophy. This debate within the Berlin academy confers a new anthropological orientation to the German philosophy of the second 18th century. (shrink)

This article is about impathy (introversive empathy), understood as the ability to share in and understand one’s own feelings, which is considered a critical psychological construct relevant for the recovery and maintenance of mental health. However, while the ability to empathize with oneself has received considerable attention from the clinical community, this has not been paralleled by the same scientific scrutiny, which was subject to the ability to empathize with others. Impathy has not yet been operationally defined and thus has (...) remained relatively unexplored, both conceptually and empirically. This work describes an operational definition of impathy with four dimensions: Perceiving, Meta-Position, Accepting Attitude, and Understanding. Issues of differentiation from related constructs are discussed and avenues of clinical applicability are explored, suggesting that impathy exists as a distinct human capacity, which can be assessed and which has important clinical implications. The paper closes with future directions, including the assessment of impathy and possible research questions. (shrink)

The focus of this paper is institutional change and the changing role of business in Germany. Back in the 1980s, the German institutional framework was characterized by implicit mandatory and obligatory regulations that set a clear context for responsible corporate behavior. Today, this framework has eroded and given way to a situation in which corporations explicitly and voluntarily take responsibility for social issues. This shift from implicit to explicit corporate social responsibility is an indication of a major institutional change epitomized (...) by the deconstruction of ‘old’ and the reconstruction of ‘new’ institutions. In the course of this change, corporations, state actors, and civil society organizations compete for their ideas and interests in what we call a fight for myths. The paper traces this fight for myths and the changing understanding of corporate responsibility in Germany. (shrink)

When Werner Herzog states, in his famous Minnesota Declaration, “[fa]cts create norms, and truth illumination”, he not only opposes his own idea of truth as spiritual experience to the notion of factual truth based on a seemingly unmediated representation of reality and purely rational principles. He also points to a societal problem inherent to such hegemonic attributions of veracity as advocated by the representatives of what he calls “Cinema Vérité”: their “truth of accountants” generates a normative perception and understanding of (...) reality. Instead of producing peculiar images that trigger the imagination, they (re)produce benchmarks, fixed values and stereotypes. Thus, they are perfectly in line with the ideology of the “administered society” (Horkheimer and Adorno, e.g. in Dialectic of Enlightenment). Based on the identity principle, this society produces standardized, consumer-friendly forms precluding the individuals from making their own, singular experiences. Films that rely purely on facts instead of seeking for “deeper strata of truth” are thus, for Herzog, not only boring, but also instruments of domination in the service of the status quo. However, Herzog neither avoids the administered society in order to search for an archaic truth beyond or underneath it, nor does he address political issues frontally in the films analyzed in this article. Critique of society rather transpires through particular configurations, notably in moments of confrontation between the “normal” society and the marginalized, “useless”, or otherwise rejected characters (as Kaspar Hauser’s encounter with representatives of the “good society, Strozeck’s misfortune, Woyzeck’s condition as the guinea pig for the sake of scientific progress, or the extravagant setting depicted in Even Dwarfs Started Small). Rather than focusing on the problematic situation of exclusion as such, Herzog emphasizes the very singularity of his protagonists in a dialectical tension with their environment, thus providing an access to the poetic truth which springs out of their individual ways of experiencing as opposed to the normative reality-principle. This is also true for many of Herzog’s documentaries: for example, Walter Steiner’s deep pleasure in ski-flying and the strange beauty of the slow-motion pictures showing him in the air highly contrast with the public pushing him to take dangerous risks and the bloody images presented in the media (The Great Ecstasy of the Woodcarver Steiner). By juxtaposing Steiner’s sensory experience and its singularized image with the societal logic of competition and its stereotyped representation, Herzog discloses the heterogeneous layers of a material truth that escapes factual accuracy. This article aims to approach Herzog’s notion of ecstatic truth by unfolding the dialectical tension between sensory, perceptual and spiritual experiences on the one hand, and the administrated society on the other. -/- . (shrink)

V článku diskutuji východiska knihy Tomáše Hříbka Jaké to je, nebo o čem to je? Cílem článku je ukázat, že přes Hříbkovy sympatie k Dennettovu postmetafyzickému pojetí vědomí lze v jeho výkladu vysledovat tendence k tradičně filosofickému myšlení o vědomí. Soustředím se přitom na Hříbkovu definici fyzikálního a na jeho charakterizaci Dennettova programu jako problematické redukce vědomí pomocí intencionality.

DesignAgility is an adaptation of the design thinking method and was developed to meet the specific needs of the publishing industry and the media sector in general. The authors of the eponymous book embedded DesignAgility into an agile framework that allows its users to effectively develop and implement media innovations with a small team. This sample chapter of the book focuses on Ideation and describes the qualified brainstorming and idea-generating in the innovation process. The needs of the users aka the (...) ‘personas’ are reflected in so-called ‘user stories’. Through refinement the ideas are developed into possible product or service features. The chapter describes detailed steps from preparation to procedure and includes a checklist of how to easily follow the instructions for ideation. The visualization of the DesignAgility process shows where this step has to be taken within the whole innovation process. (shrink)

Name der Zeitschrift: Semiotica Jahrgang: 2016 Heft: 209 Seiten: 357-370.

The 2016 United Nations’ Resolution 2325 “Non-proliferation of Weapons of Mass Destruction” manifests one of the greatest challenges for humankind in relation to preventing a global catastrophe, where it reaffirms that the proliferation of nuclear, chemical and biological weapons, as well as their means of delivery, constitutes a threat to international peace and security. However, regarding the continuous technological developments of terrestrial-based WMD aimed at orbiting space objects in near-Earth orbit, it is crucial to analyze whether, and if so, how (...) 2325 prevents their proliferation and utilization. Another relevant argument addresses the terminological factuality that, while treaty and customary law do provide some guidance on the legality of weaponization, the concept of a “space weapon” is still not clearly defined. Moreover, even though the Outer Space Treaty prohibits the placement of nuclear weapons and WMD in near-Earth orbit, installing them on the Moon or any other celestial body, or to otherwise station them in outer space, it simultaneously excludes terrestrial-based anti-satellite weapons, thus creating a legal loophole. National representatives of superpowers, particularly of space-faring nations, are aware of the existing issue and often express their concerns toward comprehensive ASAT development and utilization. Nevertheless, the potential weaponization of outer space will not be actively recognized and accepted as an official occurrence within the international community until our current space systems are eventually utilized in order to destroy or damage another State’s space object. (shrink)