Does natural selection act primarily on individual organisms, on groups, on genes, or on whole species? The question of levels of selection - on which biologists and philosophers have long disagreed - is central to evolutionary theory and to the philosophy of biology. Samir Okasha's comprehensive analysis gives a clear account of the philosophical issues at stake in the current debate.

Samir Okasha offers a critical study of agential thinking in biology, where evolved organisms are seen as agents pursuing a goal. He examines the justification for transposing concepts from rational humans to the biological world, and considers whether agential thinking is mere anthropomorphism or plays a more intellectual role in the science.

This is a conversation that took place at Dr. Vladimir Safatle’s São Paulo home on 16 February, 2019, during Dr. Samir Gandesha’s time as a Visiting Professor at the Faculdade de Filosofia, Letras e Ciências Humanas -FFLCH-USP. It addresses the South American roots of the authoritarian Neoliberalism that has now become a truly global phenomenon.

The idea that clades might be units of selection, defended by a number of biologists and philosophers of biology, is critically examined. I argue that only entities which reproduce, i.e. leave offspring, can be units of selection, and that a necessary condition of reproduction is that the offspring entity be able, in principle, to outlive its parental entity. Given that clades are monophlyetic by definition, it follows that clades do not reproduce, so it makes no sense to talk about a (...) clade's fitness, so clade selection is impossible. Three possible responses to this argument are examined and found wanting. (shrink)

Covering some of science's most divisive topics, such as philosophical issues in genetics and evolution, the philosophy of biology also encompasses more traditional philosophical questions, such as free will, essentialism, and nature vs nurture. Here, Samir Okasha outlines the core issues with which contemporary philosophy of biology is engaged.

Kin selection and multilevel selection are alternative approaches for studying the evolution of social behaviour, the relation between which has long been a source of controversy. Many recent theorists regard the two approaches as ultimately equivalent, on the grounds that gene frequency change can be correctly expressed using either. However, this shows only that the two are formally equivalent, not that they offer equally good causal representations of the evolutionary process. This article articulates the notion of an ‘adequate causal representation’ (...) using causal graphs, and then seeks to identify circumstances under which kin and multilevel selection do and do not satisfy the test of causal adequacy. 1 Introduction2 The KS and MLS Approaches2.1 The MLS decomposition2.2 The KS decomposition3 Equivalence and Causality4 Two Problem Cases4.1 The non-social trait case4.2 Genotypic selection with meiotic drive5 Casual Adequacy: A Graphical Approach5.1 The basic idea5.2 Graphs with individual and group variables5.3 Cases where KS is causally adequate5.4 Cases where MLS is causally adequate6 Discussion6.1 Relation to previous work. (shrink)

Cancer is often seen as a case of multilevel selection, in which selfish cancer cells pursue short-term proliferation to the detriment of the collective. Thus cancer cells are described as ‘cheats’, and an analogy is often drawn between the mechanisms by which organisms fight cancer and the mechanisms by which social groups enforce cooperation. Recently, Andy Gardner and Max Shpak and Jie Lu have argued that cancer is not a true case of multilevel selection, that cancer cells should be not (...) regarded as cheats, and that the analogy between anti-cancer adaptations and suppression mechanisms in social groups is misleading. Their arguments are powerful. However, by drawing on the (presumed) link between cancer and the evolution of multicellularity, the notion that cancer represents a form of selective conflict between cells and organisms can be salvaged. (shrink)

Kuhn’s famous thesis that there is ‘no unique algorithm’ for choosing between rival scientific theories is analysed using the machinery of social choice theory. It is shown that the problem of theory choice as posed by Kuhn is formally identical to a standard social choice problem. This suggests that analogues of well-known results from the social choice literature, such as Arrow’s impossibility theorem, may apply to theory choice. If an analogue of Arrow’s theorem does hold for theory choice this would (...) refute Kuhn’s thesis, but it would also pose a threat to the rationality of science, a threat that is if anything more worrying than that posed by Kuhn. Various possible ‘escape routes’ from Arrow’s impossibility result are examined, in particular Amartya Sen’s idea of ‘enriching the informational basis’. It is shown that Sen’s idea can be applied to the problem of theory choice in science. This in turn sheds light on two well-known approaches to inductive inference in philosophy of science: Bayesianism and statistical model selection. (shrink)

Derrida and the Inheritance of Democracy provides a theoretically rich and accessible account of Derrida's political philosophy. Demonstrating the key role inheritance plays in Derrida’s thinking, Samir Haddad develops a general theory of inheritance and shows how it is essential to democratic action. He transforms Derrida’s well-known idea of "democracy to come" into active engagement with democratic traditions. Haddad focuses on issues such as hospitality, justice, normativity, violence, friendship, birth, and the nature of democracy as he reads these deeply (...) political writings. (shrink)

Abstract:This paper explores the contrast between mentalistic and behaviouristic interpretations of decision theory. The former regards credences and utilities as psychologically real, while the latter regards them as mere representations of an agent's preferences. Philosophers typically adopt the former interpretation, economists the latter. It is argued that the mentalistic interpretation is preferable if our aim is to use decision theory for descriptive purposes, but if our aim is normative then the behaviouristic interpretation cannot be dispensed with.

Samir Amin depicts a world in which NATO has taken over the role of the United Nations, in which US hegemony is more or less complete, in which millions are condemned to die in order to preserve the social order of the US, Europe and Japan. Amin's analyses of the Gulf War, the wars in former Yugoslavia and the war in Central Asia reveal the scope of US strategic aims. He argues that the political and military dimension of US (...) dominance is as significant as US economic preponderance in determining the future of capitalist development. (shrink)

We propose a new relevance sensitive model for representing and revising belief structures, which relies on a notion of partial language splitting and tolerates some amount of inconsistency while retaining classical logic. The model preserves an agent's ability to answer queries in a coherent way using Belnap's four-valued logic. Axioms analogous to the AGM axioms hold for this new model. The distinction between implicit and explicit beliefs is represented and psychologically plausible, computationally tractable procedures for query answering and belief..

This volume explores from multiple perspectives the subtle and interesting relationship between the theory of rational choice and Darwinian evolution. In rational choice theory, agents are assumed to make choices that maximize their utility; in evolution, natural selection 'chooses' between phenotypes according to the criterion of fitness maximization. So there is a parallel between utility in rational choice theory and fitness in Darwinian theory. This conceptual link between fitness and utility is mirrored by the interesting parallels between formal models of (...) evolution and rational choice. The essays in this volume, by leading philosophers, economists, biologists and psychologists, explore the connection between evolution and rational choice in a number of different contexts, including choice under uncertainty, strategic decision making and pro-social behaviour. They will be of interest to students and researchers in philosophy of science, evolutionary biology, economics and psychology. (shrink)

Dept of Business Administration Dept of Computer and Knowledge Systems Group University of Patras Information Science School of Computer Science 265 00 Patras, Greece Brooklyn College of the and Engineering [email protected] City University of New York University of New South Wales Brooklyn, NY 11210, USA Sydney, NSW 2052, Australia [email protected] [email protected]..

We present a model for first-order belief revision that is characterized by an underlying relevance-like relation and a background proof system. The model is extremely general in order to allow for a wide variety in these characterizing parameters. It allows some weakenings of beliefs which were initially implicit to become explicit and survive the revision process. The effects of revision are localized to the part of the theory that is influenced by the the new information. Iterated revision in this model (...) is handled trivially since the revision operator is constructive by definition. The usage of deductively limited proof systems permits an inconsistency tolerant model. The notion of a part of a theory capable of being influenced by new information (designed to accomodate the specific character of first-order languages) is shown to satisfy some intuitive and desirable properties. We show that for particular parametrizations, standard revision schemes can be embedded into our paradigm. (shrink)

The whole of Marx's project confronts the narrow concerns of political philosophy by embedding it in social philosophy and a certain understanding of the aesthetic. From those of aesthetic production to the "poetry of the future" (as Marx writes in the Eighteenth Brumaire), from the radical modernism of bourgeois development to the very idea of association (which defined one of the main lines of tradition in the history of aesthetics), steady references to Dante, Shakespeare and Goethe, and the idea that (...) bourgeois politics is nothing but a theatrical stage: the aesthetic has a prominent place in the constellation of Marx's thought. This book offers an original and challenging study of both Marx in the aesthetic, and the aesthetic in Marx. It differs from previous discussions of Marxist aesthetic theory as it understands the works of Marx themselves as contributions to thinking the aesthetic. This is an engagement with Marx's aesthetic that takes into account Marx's broader sense of the aesthetic, as identified by Eagleton and Buck-Morss - as a question of sense perception and the body. (shrink)

If architectural judgment were a city, a city of ideas and forms, then it is a very imperfect city. When architects judge the success or failure of a building, the range of ways and criteria which can be used for this evaluation causes many contentious and discordant arguments. Proposing that the increase in number and intensity of such arguments threatens to destabilize the very grounds upon which judgment is supposed to rest, this book examines architectural judgment in its historical, cultural, (...) political, and psychological dimensions and their convergence on that most expressive part of architecture, namely: architectural character. It stresses the value of reasoned judgment in justifying architectural form -a judgment based on three sets of criteria: those criteria that are external to architecture, those that are internal to architecture, and those that pertain to the psychology of the architect as image-maker. External criteria include, philosophies of history or theories of modernity; internal criteria include architectural character and architectural composition; while the psychological criteria pertain to 'mimetic rivalry', or rivaling desires for the same architectural forms. Yet, although architectural conflicts can adversely influence judgment, they can at the same time, contribute to the advancement of architectural culture. (shrink)

In this paper, we draw inferences from the Nobel laureate Amartya Sen’s book, The Idea of Justice to inform the organisational justice literature. The extant societal-level theories of justice tend to emphasise aspects that are analogous to either the procedural or distributive dimensions of organisational justice. The Senian idea of comprehensive justice is different in that it synthesises the procedural- and distributive-related dimensions at the societal-level. We theorise that the Senian notion could be applied at the organisational-level to facilitate outcomes (...) that are actually valued by the workforce. Further, we contend that the emphasis on non-parochialism in the Senian notion of justice makes it particularly relevant to the ethics of multi-national corporations operating in alien cultures. To support our contention, we analyse the lean manufacturing practices of a Japanese MNC operating in India. Our case analysis demonstrates how Senian thinking helps one surface unjust outcomes that would otherwise go unacknowledged. Our analysis also offers tentative support to Senian claims about the capacity of human behaviour to undermine well-designed institutions. Concurring with the Senian view, which favours combating manifest injustice rather than fixating over designing perfectly just institutions, we derive some normative implications to advance the cause of striving for outcomes that are actually valued by the workforce. (shrink)

Evolutionary biology is striking for its ability to explain a large and diverse range of empirical phenomena on the basis of a few general theoretical principles. This article offers a philosophical perspective on the way that evolutionary biology has come to achieve such impressive generality, by focusing on “the strategy of endogenization”. This strategy involves devising evolutionary explanations for biological features that were originally part of the background conditions, or scaffolding, against which such explanations take place. Where successful, the strategy (...) moves biology a step closer to the ideal of explaining as much as possible from evolutionary first principles. The strategy of endogenization is illustrated through a series of biological examples, historical and recent, and its philosophical implications are explored. (shrink)

The relationship between national languages and schooling is a recurring theme in Derrida’s writings on education, playing an important role in the challenge he mounts to traditional understandings of the French State’s involvement in the teaching of philosophy. In this essay, I follow this thread of thinking across several of Derrida’s texts, paying specific attention to his diagnoses of positions arguing for a universal philosophical language on the one hand, and those elevating French as the proper language of philosophy on (...) the other. I demonstrate how, against these positions, an alternative understanding of relation between language and philosophical education starts to emerge in Derrida’s work, one in which translation is a key element. (shrink)

It is widely agreed that Hume’s description of human inductive reasoning is inadequate. But many philosophers think that this inadequacy in no way affects the force of Hume’s argument for the unjustifiability of inductive reasoning. I argue that this constellation of opinions contains a serious tension, given that Hume was not merely pointing out that induction is fallible. I then explore a recent diagnosis of where Hume’s sceptical argument goes wrong, due to Elliott Sober. Sober argues that Hume committed a (...) quantifier-shift fallacy, i.e. inferred a statement of ∃∀ form from one of V∀∃ form. The implications of this diagnosis for the traditional problem of induction are briefly examined. The author suggests that, were his philosophy received, we must alter from the foundation the greatest part of the sciences. Hume 1740. (shrink)

Several authors have recently suggested that classic psychedelics might be safe and effective agents of moral enhancement. This raises the question: can we learn anything interesting about the nature of moral experience from a close examination of transformative psychedelic experiences? The interdisciplinary enterprise of philosophical psychopathology attempts to learn about the structure and function of the “ordinary” mind by studying the radically altered mind. By analogy, in this chapter we argue that we can gain knowledge about the everyday moral life (...) by studying extraordinary experiences of altered moral cognition and experience. We focus on a specific class of cases: experiences of forgiveness induced by psychedelics. We argue that close attention to such experiences reveals the importance of thought/emotion coherence and dissonance in the moral life and vindicates some heterodox ideas about moral phenomenology and psychology. (shrink)

Group selection is one acknowledged mechanism for the evolution of altruism. It is well known that for altruism to spread by natural selection, interactions must be correlated; that is, altruists must tend to associate with one another. But does group selection itself require correlated interactions? Two possible arguments for answering this question affirmatively are explored. The first is a bad argument, for it rests on a product/process confusion. The second is a more subtle argument, whose validity (or otherwise) turns on (...) issues concerning the meaning of multi-level selection and how it should be modelled. A cautious defence of the second argument is offered. Introduction Multi-level selection and the evolution of altruism Price's equation and multi-level selection Contextual analysis and multi-level selection The neighbour approach Recapitulation and conclusion. (shrink)

What is science? Is there a real difference between science and myth? Is science objective? Can science explain everything? This Very Short Introduction provides a concise overview of the main themes of contemporary philosophy of science. Beginning with a short history of science to set the scene, Samir Okasha goes on to investigate the nature of scientific reasoning, scientific explanation, revolutions in science, and theories such as realism and anti-realism. He also looks at philosophical issues in particular sciences, including (...) the problem of classification in biology, and the nature of space and time in physics. The final chapter touches on the conflicts between science and religion, and explores whether science is ultimately a good thing. (shrink)

Hamilton’s theory of inclusive fitness is a widely used framework for studying the evolution of social behavior, but controversy surrounds its status. Hamilton originally derived his famous rb > c rule for the spread of a social gene by assuming additivity of costs and benefits. However, it has recently been argued that the additivity assumption can be dispensed with, so long as the −c and b terms are suitably defined, as partial regression coefficients. I argue that this way of generalizing (...) Hamilton’s rule to the nonadditive case, while formally correct, faces conceptual problems. (shrink)

In this paper I demonstrate that the analysis supporting Derrida’s identification of the desire for a pure, originary idiom in Heidegger’s reading of Trakl in Geschlecht III provides a framework with which we can understand the call for a new language in Monolingualism of the Other. While acknowledging how his interpretation of Heidegger provides important insights that guide Derrida’s later negotiation with the dual dangers of nationalism and colonialism, I argue that the proximity to Heidegger, manifest in Derrida’s articulation of (...) a desire for language in the singular, threatens to close down possibilities latent in the promising definition of deconstruction as plus d’une langue—both more than a language and no more of a language. (shrink)

Editor's suggested further reading in BioEssays ftz Evolution: Findings, hypotheses and speculations (response to DOI 10.1002/bies.201100019) AbstractOn the border of the homeotic function: Re‐evaluating the controversial role of cofactor‐recruiting motifs AbstractControl of DNA replication: A new facet of Hox proteins? AbstractClassification of sequence signatures: a guide to Hox protein function Abstract.

in Proceedings of the International Joint Conference on Artificial Intelligence, 2007.

Crossing Borders: Essays In Honour of Ian H. Angus is a collection of original and cutting-edge essays by eighteen outstanding and diverse Canadian and International scholars that engage with Professor Ian Angus's rich contributions to three distinct, albeit overlapping, fields: Canadian Studies, Phenomenology and Critical Theory, and Communication and Media Studies. These contributions are distinct, unique, and have had resonance across the intellectual landscape over the thirty years that Angus has been teaching communications, philosophy, Canadian Studies, theory, and humanities first (...) in the United States and then in Canada. (shrink)

Numerous eukaryotic DNA processing enzymes, such as DNA polymerases and ligases, bind the processivity factor PCNA, which acts as a platform to recruit and regulate the binding of enzymes to their DNA substrate. Multiple PCNA‐interacting motifs (PIPs) are present in these enzymes, but their individual structural and functional role has been a matter of debate. Recent cryo‐EM reconstructions of high‐fidelity DNA polymerase Pol δ (Pol δ), translesion synthesis DNA polymerase κ (Pol κ) and Ligase 1 (Lig1) bound to a DNA (...) substrate and PCNA demonstrate that the critical interaction with PCNA involves the internal PIP proximal to the catalytic domain. The ancillary PIPs, located in long disordered regions, are instead invisible in the reconstructions, and appear to function as flexible tethers when the enzymes fall off the DNA. In this review, we discuss the recent structural advancements and propose a functional hierarchy for the PIPs in Pol δ, Pol κ, and Lig1. (shrink)

This paper provides a philosophical analysis of the ongoing controversy surrounding R.A. Fisher's famous ‘fundamental theorem’ of natural selection. The difference between the ‘traditional’ and ‘modern’ interpretations of the theorem is explained. I argue that proponents of the modern interpretation have captured Fisher's intended meaning correctly and shown that the theorem is mathematically correct, pace the traditional consensus. However, whether the theorem has any real biological significance remains an unresolved issue. I argue that the answer depends on whether we accept (...) Fisher's non-standard notion of environmental change, on which the theorem rests; arguments for and against this notion are explored. I suggest that there is a close link between Fisher's fundamental theorem and the modern ‘gene's eye’ view of evolution. Introduction What Does the Fundamental Theorem Say? Key Concepts Explained Alleged Significance of the FTNS Traditional versus Modern Interpretations of the FTNS The Modern Interpretation Illustrated Fisher's Concept of ‘Environmental Change’ Causality and the Modern Interpretation The Significance of the FTNS Re-considered Appendix CiteULike Connotea Del.icio.us What's this? (shrink)

We present a method for relevance sensitive non-monotonic inference from belief sequences which incorporates insights pertaining to prioritized inference and relevance sensitive, inconsistency tolerant belief revision. Our model uses a finite, logically open sequence of propositional formulas as a representation for beliefs and defines a notion of inference from maxiconsistent subsets of formulas guided by two orderings: a temporal sequencing and an ordering based on relevance relations between the putative conclusion and formulas in the sequence. The relevance relations are ternary (...) (using context as a parameter) as opposed to standard binary axiomatizations. The inference operation thus defined easily handles iterated revision by maintaining a revision history, blocks the derivation of inconsistent answers from a possibly inconsistent sequence and maintains the distinction between explicit and implicit beliefs. In doing so, it provides a finitely presented formalism and a plausible model of reasoning for automated agents. (shrink)

The idea that natural selection can operate on cultural as well as genetic variation is central to recent theories of cultural evolution. This raises an overarching question: how much of traditional evolutionary theory, which was formulated in population-genetic terms, can survive intact once the possibility of cultural inheritance is taken into account? This question is addressed in relation to R. A. Fisher’s “fundamental theorem” of natural selection. Though Fisher’s theorem may appear to be an essentially genetic result, a version of (...) the theorem can be derived that applies to any evolving population, with an arbitrary inheritance mechanism. However, I argue that the biological significance of this “generalized” version of the fundamental theorem is less than that of the Fisherian original. (shrink)

This paper compares two well-known arguments in the units of selection literature, one due to , the other due to . Both arguments concern the legitimacy of averaging fitness values across contexts and making inferences about the level of selection on that basis. The first three sections of the paper shows that the two arguments are incompatible if taken at face value, their apparent similarity notwithstanding. If we accept Sober and Lewontin's criterion for when averaging genic fitnesses across diploid genotypes (...) is illegitmate, we cannot accept Sober and Wilson's criterion for when averaging individual fitnesses across groups is illegitimate, and vice versa. The final section suggests a possible way of reconciling the two arguments, by invoking an ambiguity in the concept of genic selection. (shrink)

In this paper, I explore Larry Laudan's and Jarrett Leplin's recent claim that empirically equivalent theories may be differentially confirmed. I show that their attempt to prise apart empirical equivalence and epistemic parity commits them to two principles of confirmation that Hempel demonstrated to be incompatible.

Biologists and philosophers of biology typically regard essentialism about speciesas incompatible with modern Darwinian theory. Analytic metaphysicians such asKripke, Putnam and Wiggins, on the other hand, believe that their essentialist thesesare applicable to biological kinds. I explore this tension. I show that standard anti-essentialist considerations only show that species do not have intrinsic essential properties. I argue that while Putnam and Kripke do make assumptions that contradict received biological opinion, their model of natural kinds, suitably modified, is partially applicable to (...) biological species. However, Wiggins'' thesis that organisms belong essentially to their species is untenable, given modern species concepts. I suggest that Putnam''s, Kripke''s and Wiggins'' errors stem from adopting an account of the point of scientific classification which implies that relationally-defined kinds are likely to be of little value, an account which is inapplicable to biology. (shrink)

The levels of selection problem was central to Maynard Smith’s work throughout his career. This paper traces Maynard Smith’s views on the levels of selection, from his objections to group selection in the 1960s to his concern with the major evolutionary transitions in the 1990s. The relations between Maynard Smith’s position and those of Hamilton and G.C. Williams are explored, as is Maynard Smith’s dislike of the Price equation approach to multi-level selection. Maynard Smith’s account of the ‘core Darwinian principles’ (...) is discussed, as is his debate with Sober and Wilson (1998) over the status of trait-group models, and his attitude to the currently fashionable concept of pluralism about the levels of selection. (shrink)