In this work we report a simple way to assign a single numeric value in a three-dimensional space to a given nucleotide sequence. The method reported allows for theoretical comparisons of naturally occurring nucleotide sequences.

It is a mistake to oppose law and grace, for God's grace makes way for a radically transformed social and moral order. The law of Christ enables a new way of life that is obedient to God.

A la hora de pensar lo más inmediato a nosotros mismos es necesario acudir a lo que somos en cuanto Dasein. Sin embargo, la experiencia de lo inmediato tiene la condición de presentarse bajo la forma de un extrañamiento, un «no saber». Se verá que la corporeidad y su extrañamiento abren a la posibilidad de una hermenéutica de nuestra propia condición porque la experiencia de lo Unheimlich es una vía de epojé que «detona» (revienta) la cadena de significaciones habitual y (...) reconfigura la experiencia. Se tomará como punto de referencia cuatro casos icónicos: 1) la convalecencia de Oliver Sacks, 2) el famoso caso Paul Schreber, 3) la referencia al joven esquizofrénico en los Seminarios de Zollikon, e incluso 4) el desfallecimiento de Heidegger entre los años 1945 y 1946, todo esto a la luz del extrañamiento de lo íntimo y la posibilidad que este abre a un «reordenamiento interno». En definitiva, las patologías y lo terrorífico que las acompaña son capaces de generar las condiciones de un vitalismo inusitado, pues solo quien se ha enfrentado a la más radical convulsión de todas sus verdades, podrá «abrirse camino» en medio del exceso de donación que desborda su «realidad». (shrink)

La perspectiva que estudiantes de docencia tienen sobre las disciplinas inherentes a la educación y en el logro del perfil de egreso, es multifacética; hay quienes conciben con mayor peso la psicología, didáctica y filosofía, otros incluyen sociología y antropología, pero pocos incluyen la neuropedagogía; por lo que dicha visión poco incide en decisiones para emocionar el cerebro para aprender.

Little is known on the appraisal of ethically questionable not- for-profit actions such as social marketing advertising campaigns. The present study evaluates the ethical acceptance by adults of anti-obesity threat appeals targeting children, depending on the claimed effectiveness of the campaign. An experiment conducted among 176 Belgian participants by means of an online survey shows that individuals’ acceptance of social marketing practices increases along with the claimed effectiveness of the campaign. As such it demonstrates that the audience adopts a pragmatic (...) perspective, challenging the non-consequentialist stance of social marketers who refrain themselves from using these ‘questionable’ techniques although highly effective. The trade-off between ethical judgment and claimed effectiveness varies depending on whether the threats focus on the child’s physical integrity or social life. Individual characteristics such as parenthood and age also influence the relationship. All in all, it seems that people with stronger connections to the issue such as parents are more ready to compromise. These findings enrich our insights into consequentialism in social marketing campaigns, how people respond to controversial messages targeted at vulnerable group, and open new venues to social managers and public policy makers. Managerial implications and concrete advice on how to communicate with the various audiences are proposed, as well as suggestions for future studies. (shrink)

In this paper, I am concerned with the possibility of applying an abductive strategy in founding ethical realism. First, I criticize Harman’s position, according to which abduction, though useful for founding scientific realism, does not serve to found ethical realism. Secondly, I examine Sturgeon’s critique, according to which distinctively moral facts do constitute the best explanations of the moral evidence. Finally,I conclude that Sturgeon is right in as far as the ontological status of moral properties is concerned but his answer (...) to Harman’s point is not properly developed. (shrink)

This article analyses the phenomenon of ‘micro-domination’, in which a series of dominated choices are individually inconsequential for a person’s freedom but collectively consequential. Where the choices concerned are objectively inconsequential, micro- domination poses a problem for ‘objective threshold’ accounts of domination which either prioritise particularly bad forms of domination or exclude powers that do not risk causing serious harm to their victims. Where the choices concerned are subjectively inconsequential to the victim, micro-domination poses a problem for the common republican (...) strategy of creating arenas of contestation for victims of domination, which rely on victims objecting strongly enough to a dominating relationship to sound the alarm. This kind of invigilation may systematically fail victims of micro-domination. Throughout the article, I suggest some ways of better accounting for and responding to cases of micro-domination. (shrink)

In this essay I defend the view that dogwhistling is a a speech act performed with a narrative-evoking perlocutionary effect in the so-called target audience. What is evoked is a certain kind of narrative, previously endorsed by the relevant audience, which endows its members with the use of some linguistic expressions (and some non-linguistic representations) with non-conventional, derived meanings. In the dogwhistling scenarios, those derived meanings are recovered and put to work by means of different mechanisms, which has an impact (...) on the emotional and practical attitudes of the target audience. The covert message is thus inferred as the product of the recovered meanings at work and their emotional and practical impacts on the audience in the new contexts of use, which determines a new pragmatic meaning dimension for the expressions in play. Although the phenomenon has been frequently analyzed in connection with examples of political discourse, it is common to cinematographic and literary intertextual references, and, more generally, to all those occasions in which communication relies on the narrative dependance of linguistic use. (shrink)

_El deshabitado _(Grijalbo, 2016) puede estudiarse como un testimonio novelado, porque es un relato complejo y sobrecogedor en primera persona, escrito por el poeta Javier Sicilia, quien se representa como protagonista y testigo de las terribles causas sociales de la muerte de su hijo Juanelo, y de las consecuencias que tuvo sobre Sicilia ese fatídico hecho. En la lectura, asistimos al recuento del duelo del escritor y a la rememoración de la posterior fundación del Movimiento por la Paz con Justicia (...) y Dignidad, manifestación civil contra la llamada Guerra contra el Narco gubernamental en México entre 2006 y 2012. Hecho social y memoria íntima se funden en el libro analizado. La hipótesis de esta investigación es que se pueden reconocer elementos retóricos y técnicos usados para construir un _testimonio de lo inefable. _¿Cómo logra Sicilia la fusión entre técnica lírica y testimonio, para configurar un punto equilibrado entre lo afectivo, lo artístico y lo mnemónico? ¿Cuáles son las implicaciones estéticas de este singular ejercicio literario? En la medida que el autor del corpus de estudio se afirma como un testigo-memorialista que revisa un momento álgido de la historia mexicana, la narración, obviamente, se convierte en un testimonio-memoria de primera mano del periodo. Asimismo, la conciencia histórica, pero sobre todo la conciencia literaria y la _sospecha de la palabra _al (d)escribir tanto su dolor como padre como la posición sociológica de Sicilia, permiten problematizar las relaciones entre escritura y violencia, entre arte y tiempo presente. Tales fueron los objetivos aquí. (shrink)

When people understand a counterfactual such as “if the flowers had been roses, the trees would have been orange trees,” they think about the conjecture, “there were roses and orange trees,” and they also think about its opposite, the presupposed facts. We test whether people think about the opposite by representing alternates, for example, “poppies and apple trees,” or whether models can contain symbols, for example, “no roses and no orange trees.” We report the discovery of an inference‐to‐alternates effect—a tendency (...) to make an affirmative inference that refers to an alternate even from a negative minor premise, for example, “there were no orange trees, therefore there were poppies.” Nine experiments show the inference‐to‐alternates effect occurs in a binary context, but not a multiple context, and for direct and indirect reference; it can be induced and reduced by prior experience with similar inferences, and it also occurs for indicative conditionals. The results have implications for theories of counterfactual conditionals, and of negation. (shrink)

En las últimas seis décadas el fenómeno del autoengaño ha sido objeto de creciente interés no sólo en el ámbito de la filosofía, dentro de la cual fue tradicionalmente estudiado, sino también en el de distintas ciencias, entre ellas la psicología, las neurociencias, la biología evolucionista y las ciencias sociales. Este incremento en el interés ha redundado en una proliferación de interrogantes y propuestas teóricas de muy diversas clases, sin que hasta la fecha se haya logrado una teoría unificada que (...) goce de consenso respecto del fenómeno. En el presente artículo se presentan las preguntas que contemporáneamente se consideran más relevantes sobre el autoengaño, tanto dentro del dominio de la filosofía como en el de diversas ciencias. Asimismo, se analizan algunos problemas conceptuales y epistemológicos derivados de la proliferación de estudios sobre el fenómeno, y se examinan algunas de las líneas de investigación más recientes y promisorias desarrolladas con el fin de resolver algunas dificultades conceptuales bien conocidas. (shrink)

La meritocracia es sinónimo de conocimientos o prácticas, que se jerarquizan y estratifican de acuerdo a principios de excelencia y competencia, dirección y capacitación, para la toma de decisiones. Una sociedad o institución es meritocrática, en la medida que se orienta por valores de máxima ..

Entendida como “la manera de vivir la historia, en cierto modo como condena o como fatalidad”, la fe ha sido recibida. Y esta ha sido transmitida en términos como en los que se sostiene que la filosofía debe aprenderse en Europa o Norteamérica, que nuestra economía es dependiente y que la piel y sangre que llevamos es impura. Para Vargas Guillén, la tragedia de nuestra historia se explica en parte por una educación patriarcalista que entrena solo para obedecer. Por esta (...) razón, su propuesta en este libro es la de una deconstrucción fenomenológica del patriarcalismo que conduce a la superación de la economía del don en busca del sentido del amor “como proyecto y desenvolvimiento del ser”, lo cual es posible si se da el paso del estudio del fenómeno religioso al estudio de Dios como fenómeno. Como ejemplo para dar dicho paso, el autor retoma un texto del escritor Juan Rulfo, Talpa, publicado en 1950. Se trata, según él, “de la acción pasiva de la culpa; esta ha sido creada mediante mecanismos de autoridad y se ha entronizado por vía de la experiencia religiosa”. (shrink)

The present article aims to utilize some insights from behavioral and happiness economics to discuss the consequences that the introduction of an unconditional basic income to cope with technological unemployment may hold for well-being. The impact of 21st-century technological progress on employment has only just begun to make itself felt and it will take time to realize its full extent. However, the main innovation is already common knowledge: robots are finding their way into the production process. According to several recent (...) contributions, the phenomenon is radically different from past technological revolutions and could generate high levels of unemployment, calling for innovative redistributive public policies. The present article, building on Keynes’ short essay and referring to some of the principles and models of behavioral and happiness economics, focuses on the best-known of these policies, namely provision of an unconditional basic income. A series of factors – loss aversion and hedonic adaptation, the impossibility of escalating to higher-grade consumption behaviors, social interaction in the form of active and passive envy, loss of self-esteem and social stigma – are all likely to have a negative impact on well-being if an unconditional basic income that remains unchanging over time is implemented. A policy mix combining a rising basic income with other measures is therefore proposed. (shrink)

We examine two competing effects of beliefs on conditional inferences. The suppression effect occurs for conditionals, for example, “if she watered the plants they bloomed,” when beliefs about additional background conditions, for example, “if the sun shone they bloomed” decrease the frequency of inferences such as modus tollens (from “the plants did not bloom” to “therefore she did not water them”). In contrast, the counterfactual elevation effect occurs for counterfactual conditionals, for example, “if she had watered the plants they would (...) have bloomed,” when beliefs about the known or presupposed facts, “she did not water the plants and they did not bloom” increase the frequency of inferences such as modus tollens. We report six experiments that show that beliefs about additional conditions take precedence over beliefs about presupposed facts for counterfactuals. The modus tollens inference is suppressed for counterfactuals that contain additional conditions (Experiments 1a and 1b). The denial of the antecedent inference (from “she did not water the plants” to “therefore they did not bloom”) is suppressed for counterfactuals that contain alternatives (Experiments 2a and 2b). We report a new “switched‐suppression” effect for conditionals with negated components, for example, “if she had not watered the plants they would not have bloomed”: modus tollens is suppressed by alternatives and denial of the antecedent by additional conditions, rather than vice versa (Experiments 3a and 3b). We discuss the implications of the results for alternative theories of conditional reasoning. (shrink)

Despite mounting evidence that abusive supervision triggers interpersonal aggression, much remains unknown regarding the underlying causal mechanisms within this relationship. We explore the role of turnover intentions as a mediator in the relationship between abusive supervision and subsequent supervisor-rated interpersonal aggression. We use a sample of 324 supervisor–subordinate dyads from nine organizations and find support for this mediation effect. Furthermore, we find that power-distance orientation and perceived human resource support climate, as important boundary conditions, independently interact with abusive supervision to (...) weaken this positive impact on turnover intentions, thereby reducing interpersonal aggression. We also find via turnover intentions that abusive supervision intensifies interpersonal aggression among high power-distance-oriented individuals when the HR support climate is perceived to be low. Theoretical and practical implications are discussed. (shrink)

The construct of autonomy appears in the literature associated with individual psychological wellbeing. In Ryff's model, autonomy is presented as one of the dimensions of wellbeing, along with self-acceptance, positive relationships with others, environmental mastery, purpose in life, and personal growth. The present study compared the levels of autonomy and psychological wellbeing between Spanish and Colombian young people. Ryff's Scale of Psychological Wellbeing and the Transition to Adulthood Autonomy (EDATVA according to its initials in Spanish) scales were used on a (...) sample of 1,146 young people aged between 16 and 21; 506 Spanish and 640 Colombian. Results showed differences in autonomy and in two of the four dimensions proposed by the EDATVA: self-organization and critical thinking. Similarly, important differences were observed in the subscales of positive relations and purpose in life. The importance of contextual factors in the development of psychological well-being and autonomy in young people in transition to adulthood is discussed. (shrink)

Este artículo busca avizorar, desde el terreno de las pretensiones del humanismo, la posibilidad de una ética desprovista de «centro» que se asiente en la «compasión». Se buscará comprender la necesidad de abandonar los intentos de retornar al proyecto «humanístico» y se señalará su mayor riesgo: el «cínico ilustrado». Adicionalmente, se considerará «el humanismo» como el solemne destello de una «estrella que murió hace mucho» pero que da señales para la construcción de una ética excéntrica fundada en la compasión y (...) el dolor. Para tales efectos, se presentarán tres secciones: a) el humanista un cínico ilustrado b) mecanismos de evasión. La miseria y el modo de vida burgués y c) la ausencia de centro y la posibilidad de una ética excéntrica. (shrink)

We report five experiments showing that the activation of the end-terms of a syllogism is determined by their position in the composite model of the premises. We show that it is not determined by the position of the terms in the rule being applied (Ford, 1994), by the syntactic role of the terms in the premises (Polk & Newell, 1995; Wetherick & Gilhooly, 1990), by the type of conclusion (Chater & Oaksford, 1999), or by the terms from the source premise (...) (Stenning & Yule, 1997). In our first experiment we found that after reading a categorical premise, the most active term is the last term in the premise. In Experiments 2, 3, and 4 we demonstrated that this pattern of activity is due to the position of the concepts in the model of the premises, regardless of the delay after reading the premises (150 or 2000 msec) or the quantity of the quantifiers (universal or existential). The fifth experiment showed that the pattern switches around after participants evaluate a conclusion. We propose that the last element in the model maintains a higher level of activity during the comprehension process because it is generally used to attach the incoming information. After this process, the first term becomes more active because it is the concept to which the whole representation is referred. These results are predicted by the mental model theory (Johnson-Laird & Byrne, 1991), but not by the verbal reasoning theory (Polk & Newell, 1995), the graphical methods theory (Yule & Stenning, 1992), the attachment-heuristic theory (Chater & Oaksford, 1999), or the mental rules theory (Ford, 1994). (shrink)

En la historiografía nacional poco se ha estudiado el problema de la lectura y la confrontación del sentido del pasado en la historia de la revolución durante la tercera década del siglo xix. El objetivo de este artículo es reconstruir las prácticas lectoras a partir de las cuales se asumió una posición crítica y se construyó cierta opinión pública frente a la narración de los hechos del pasado republicano vinculado con los procesos de independencia en la Nueva Granada. Para ello, (...) se examina la defensa de José Fernández Madrid frente a los testimonios, narrativas y lo que llamaba la “desnaturalización de los hechos” en la naciente historia de Colombia, que se empezó a inventar después de los sucesos de Boyacá en 1819 y luego de sancionada la Constitución Política de 1821. Se quiere llamar la atención, por un lado, sobre los criterios de veracidad a los que eran sometidos los testimonios de los protagonistas de la Independencia al momento de ser confrontados con la interpretación, los documentos y las pruebas del lector; y, por otro, sobre los usos que hacían del pasado los republicanos ilustrados para justificar su “conducta política” y mantener el “buen nombre”, justo cuando se estaban inventando y legitimando los fundamentos políticos de la nueva República. En este sentido, se trata, desde el punto de vista metodológico, de avanzar en el campo de la historia de la lectura a partir de un análisis de las discusiones, defensas, comentarios y contestaciones del público lector, para legitimar su actitud crítica frente a las formas de desconocimiento suscitadas por la escritura de la historia. (shrink)