Mental and behavioral disorders represent a significant portion of the public health burden in all countries. The human cost of these disorders is immense, yet treatment options for sufferers are currently limited, with many patients failing to respond sufficiently to available interventions and drugs. High quality ontologies facilitate data aggregation and comparison across different disciplines, and may therefore speed up the translation of primary research into novel therapeutics. Realism-based ontologies describe entities in reality and the relationships between them in (...) such a way that – once formulated in a suitable formal language – the ontologies can be used for sophisticated automated reasoning applications. Reference ontologies can be applied across different contexts in which different, and often mutually incompatible, domain-specific vocabularies have traditionally been used. In this contribution we describe the Mental Functioning Ontology (MF) and Mental Disease Ontology (MD), two realism-based ontologies currently under development for the description of humanmental functioning and disease. We describe the structure and upper levels of the ontologies and preliminary application scenarios, and identify some open questions. (shrink)

This chapter examines a question at the intersection of the mind-body problem and the analysis of mental representation: the question of the direction of constraint between psychological fact and theory and neurophysiological or physical fact and theory. Does physiology constrain psychology? Are physiological facts more basic than psychological facts? Or do psychological theories, including representational analyses, guide and constrain physiology? Despite the antireductionist bent of functionalist positions, it has generally been assumed that physics or physiology are more basic than, (...) and hence contraining on, psychological fact and theory. Section 1 sketches the intuitions that would lead one to adopt such a view. The chapter then examines whether one-sided constraint has been and should be found in practice. It argues that philosophical analysis of psychological science shows that rigorous functional analyses can be carried out in advance of physiological knowledge. Indeed, in the investigation of sensory perception, ascription of psychological function leads the way in the individuation and investigation of neurophysiology. We shall look at several cases in visual perception (binocular single vision, stereopsis, and color vision), in which psychological results have provided a basis for physiological research. It is tempting to think that the psychological functions that enable physiological investigation would be Wrightian teleofunctions. It is, thus, natural to suppose that psychologists and neurophysiologists have proceeded with a conception of the purpose of a given neural structure, and have viewed neural anatomy and neural activity as the substrate for or instantiation of various properly psychological functions. For example, neuroscientists surely understand that the eye and visual system are for seeing, rather than for detecting an electric discharge in the vicinity of the retina (which sighted humans can do, via the subjective light produced by such discharges), and they guide their investigations of the eye, visual cortex, and intervening pathways accordingly. As a result, they will view rods and cones in the eye as photoreceptors, even though these structures will produce "output" (will respond with hyperpolarization) to other forms of energy. At the same time, there may be cases in which the functions that have guided research are in fact precisely determined input-output functions, whose teleofunctional status is absent or misdescribed. I will argue that in the case of trichromatic color matches, the psychological function involved is an input-output function, and that this result has implications for the description of color vision as a psychological capacity. (shrink)

This chapter discusses what is the specific difference of mental function, relative to the general concept of a biological function. It contrasts various approaches of this problem through evolutionary psychology, developmental system theory and neuroscientific growth theory models. It concludes that an holistic, dynamic approach to mental function suggests to reject the traditional division in mental faculties.

This paper samples the large body of neuroscientific evidence suggesting that each mental function takes place within specific neural structures. For instance, vision appears to occur in the visual cortex, motor control in the motor cortex, spatial memory in the hippocampus, and cognitive control in the prefrontal cortex. Evidence comes from neuroanatomy, neurophysiology, neurochemistry, brain stimulation, neuroimaging, lesion studies, and behavioral genetics. If mental functions take place within neural structures, mental functions cannot survive brain death. (...) Therefore, there is no mental life after brain death. -/- 1. The Neural Localization of Mental Functions - 1.1 Perception and Motor Control - 1.2 Memory - 1.3 Emotion - 1.4 Language - 1.5 Thinking - 1.6 Attention and Consciousness - 1.7 Spirituality -- 2. Objections - 2.1 Linguistic Dualism - 2.2 Mere Correlation - 2.3 Neural Plasticity - 2.4 Intentionality - 2.5 Phenomenal Consciousness - 2.6 Subjectivity - 2.7 Self-Knowledge - 2.8 Free Will - 2.9 Are We Just Indulging in Physicalistic Wishful Thinking? -- 3. Conclusion -- Appendix: Physicalism and the Afterlife. (shrink)

We propose that to understand the biological and neurophysiological processes that give rise to human mental phenomena it is necessary to consider them as behavioral relational phenomena. In particular, we propose that: a) these phenomena take place in the relational manner of living that human language constitutes, and b) that they arise as recursive operations in such behavioral domain. Accordingly, we maintain that these phenomena do not take place in the brain, nor are they the result of a unique (...) operation of a human brain, but arise with the participation of the brain as it generates the behavioral relational dynamics that constitutes language. (shrink)

A biophysical and biochemical perspective of Brahmajnaana will be advanced by viewing Upanishads and related books as “Texts of Science on human mind”. A biological and cognitive science insight of Atman and Maya, the results of breathing process; constituting and responsible for human consciousness and mental functions will be developed. The Advaita and Dvaita phases of human mind, its cognitive and functional states will be discussed. These mental activities will be modeled as brain-wave modulation and demodulation processes. (...) The energy-forms and their transformations as ideas/moods/experiences/thoughts/feelings/utterances/knowing/perception/experience/mood; and a theory of human cognition and communication will be advanced. The sameness of these and processes taking place and steps involved in human language acquisition and communication processes will be highlighted taking ideas from Sabdabrahma Siddhanta and Sphota Vaada, for which the basis is Brahmajnaana only. In fine, a physiological psychological and neurological model of human consciousness and function of mind based on Indian spiritual thought will be derived and discussed using concepts from modern science and technology. The application of these derivations in the fields of physiological psychology, mind-machine modeling, natural language comprehension branch of artificial intelligence and neurology to model and imitate human mental functions will be hinted. -/- . (shrink)

This study focuses on the influence of the work of Carl Stumpf on the thought of Karl Bühler. Our working hypothesis is based on the philosophical program that Bühler attributes to Stumpf and to which several of his works are largely indebted. It is divided into five parts. The first is intended to establish a relationship between Bühler and the School of Brentano to which Stumpf belongs. In the second, I show that Bühler became aware of Brentano's ideas and of (...) Stumpf's program during a stay at the Institute of Psychology of Berlin during the winter semester 1904-1905, and I briefly comment, in the third part, Bühler's references to the work of Stumpf and two of his books in which he defends Stumpf's program against his critics. After having established the solid knowledge that Bühler had of Stumpf's work, I outline, in the fourth part, the main aspects of this program and evaluate, in the fifth, how Bühler uses it in the field of sensory phenomena (gestalt). I conclude this study with several remarks on Stumpf's positive evaluation of the work of Bühler. (shrink)

Human consciousness, as dealt with in the Upanishads, modeled as a mechanical oscillator of infrasonic frequency (the Atman/Brahman), the result of breathing process, is further advanced to get an insight of functions of mind. An analytical approach is followed in parallel to and separette from quantum mechanical, quantum field and other theoretical propositions, approaches and presentations. Pure consciousness, unoccupied awareness and occupied awareness are identified, defined, classified and discussed together with fresh insight about time-space and time. A reversible transformation (...) (vivartanam) of virtual mental energy reflection (maya), creating various consequential / parallel / simultaneous conscious-states, phases, cognitive and communicative states, modes of language acquisition and communication, and kinds of function of human mind, which forms and facilitates human mental acquisitions, functions and communications, is proposed and discussed. Alternative analytical insight of human consciousness and mental functions to other theoretical approaches is given. All this is presented in brain wave modulation / demodulation terms. -/- . (shrink)

Recent advances in the cognitive sciences suggest that cognition is grounded in our embodied experience. This article supports this claim by analyzing the way we conceptualize our emotions metaphorically in terms of bodily processes. Our emotions are not merely matters of subjective feeling. Rather, emotions have stable conceptual structures that have emerged from our embodied activity through metaphorical projections, structures that are shared in a culture and can be disclosed by empirical inquiry. This article explores the metaphorical structuring of anxiety (...) in terms of our experience of breathing. The correlation in our experience between mental functioning and bodily functioning, which leads to the emergence of metaphorical understanding, is of special concern. The article elaborates on how features of our experience of inhibited breathing map onto our experience of mental disquietude. The analysis draws primarily from Johnson (1987), Lakoff (1987), Lakoff and Johnson (1980), and Reddy (1979) and borrows insight from James and Perls. (shrink)

Due to several socio-political factors, to many psychiatrists only a strictly objective definition of mental disorder, free of value components, seems really acceptable. In this paper, I will explore a variant of such an objectivist approach to defining metal disorder, natural function objectivism. Proponents of this approach make recourse to the notion of natural function in order to reach a value-free definition of mental disorder. The exploration of Christopher Boorse's 'biostatistical' account of natural function (1) will be followed (...) an investigation of the 'hybrid naturalism' approach to natural functions by Jerome Wakefield (2). In the third part, I will explore two proposals that call into question the whole attempt to define mental disorder (3). I will conclude that while 'natural function objectivism' accounts fail to provide the backdrop for a reliable definition of mental disorder, there is no compelling reason to conclude that a definition cannot be achieved. (shrink)

The present study aimed to examine the neural mechanisms underlying the ability to process the mental rotation with mirrored stimuli for different depressive tendencies with psychomotor retardation. Using functional near-infrared spectroscopy, we measured brain cortex activation of participants with higher and lower depressive tendencies while performing a left-right paradigm of object mental rotation or a same-different paradigm of subject mental rotation. Behavioral data revealed no differences in reaction time and rotation speed. The fNIRS data revealed a higher (...) deactivation of oxyhemoglobin change for the higher depression group in the perceptual stage of object mental rotation with mirrored stimuli in the superior external frontal cortex, inferior frontal gyrus, premotor cortex, and primary motor cortex. In addition, there existed a significant difference between the two groups in premotor cortex in subject mental rotation with mirrored stimuli. These results suggest that the neural mechanism of higher depression individuals connected with psychomotor retardation exists in the frontal and motor areas when processing object mental rotation with mirrored stimuli, and the motor cortex when processing subject mental rotation. (shrink)

Collecting the work of linguists, psychologists, neuroscientists, archaeologists, artificial intelligence researchers and philosophers this volume presents a richly varied picture of the nature and function of mental states. Starting from questions about the cognitive capacities of the early hominin homo floresiensis, the essays proceed to the role mental representations play in guiding the behaviour of simple organisms and robots, thence to the question of which features of its environment the human brain represents and the extent to which complex (...) cognitive skills such as language acquisition and comprehension are impaired when the brain lacks certain important neural structures. Other papers explore topics ranging from nativism to the presumed constancy of categorization across signed and spoken languages, from the formal representation of metaphor, actions and vague language to philosophical questions about conceptual schemes and colours. Anyone interested in mental states will find much to reward them in this fine volume. (shrink)

Over the past few decades, Jaegwon Kim has argued that non-reductive physicalism is an inherently unstable position. In his view, the most serious problem is that non-reductive physicalism leads to type epiphenomenalism—the causal inefficacy of mental properties. Kim suggests that we can salvage mental causation by endorsing functional reduction. Given the fact that Kim’s goal in formulating functional reduction is to provide a robust account of mental causation it would be surprising if his position implies eliminativism about (...) mental properties or leads to a view that is similar to one of the versions of non-reductive physicalism that he criticizes. We will show that depending on how certain key claims are interpreted, there are reasons for thinking functional reduction has these implications, in which case either Kim fails to provide a robust account of mental causation or there is reason to suspect that some of his criticisms of non-reductive physicalism are misguided. (shrink)

There has been considerable recent philo- sophical work on the nature of mental illness. Two..

Naturalistic accounts of mental disorder aim to identify an objective basis for attributions of mental disorder. This goal is important for demarcating genuine mental disorders from artificial or socially constructed disorders. The articulation of a demarcation criterion provides a means for assuring that attributions of 'mental disorder' are not merely pathologizing different forms of social deviance. The most influential naturalistic and hybrid definitions of mental disorder identify biological dysfunction as the objective basis of mental (...) disorders: genuine mental... (shrink)

This study investigated the impact of maternal reflective functioning (RF) and attachment security on children’s mentalization. The Adult Attachment Interview (AAI) was administered to mothers in a sample of 41 mother–preadolescent dyads. AAI transcripts were rated in terms of the Berkeley AAI System ( Main and Goldwyn, 1998 ) and the Reflective Functioning Scale (RFS; Fonagy et al., 1998 ). Preadolescent mentalization was assessed using a semi-structured interview adapted from O’Connor and Hirsch (1999) and also by analyzing mental-state talk (...) produced during an autobiographical interview. Relationships between maternal RF and children’s mentalization were analyzed, with consideration given to the different RFS markers and references to positive, negative, and mixed-ambivalent mental states. Children’s mentalization was positively correlated with the mother’s RF, particularly the mother’s ability to mentalize negative or mixed-ambivalent mental states. No significant differences in mentalization were observed between children of secure and insecure mothers. (shrink)

I clarify some of the details of the modal theory of function I outlined in Nanay (2010): (a) I explicate what it means that the function of a token biological trait is fixed by modal facts; (b) I address an objection to my trait type individuation argument against etiological function and (c) I examine the consequences of replacing the etiological theory of function with a modal theory for the prospects of using the concept of biological function to explain mental (...) content. (shrink)

Representations are not only used in our folk-psychological explanations of behaviour, but are also fruitfully postulated, for example, in cognitive science. The mainstream view in cognitive science maintains that our mind is a representational system. This popular view requires an understanding of the nature of the entities they are postulating. Teleosemantic theories face this challenge, unpacking the normativity in the relation of representation by appealing to the teleological function of the representing state. It has been argued that, if intentionality is (...) to be explained in teleological terms, then the function of a state cannot depend on its phylogenetical history, given the metaphysical possibility of a duplicate of an intentional being that lacks an evolutionary history. In this paper, I present a method to produce, according to our current knowledge in genetic engineering, human-like individuals who are not the product of natural selection in the required sense. This variation will be used to shed light on the main replies that have been offered in the literature to the Swampman thought experiment. I argue that these replies are not satisfactory: representations should better not depend on natural selection. I conclude that a non-etiological notion of function is to be preferred for characterizing the relation of representation. (shrink)

Cowan argues that the true short-term memory (STM) capacity limit is about 4 items. Functional neuroimaging data converge with this conclusion, indicating distinct neural activity patterns depending on whether or not memory task-demands exceed this limit. STM for verbal information within that capacity invokes focal prefrontal cortical activation that increases with memory load. STM for verbal information exceeding that capacity invokes widespread prefrontal activation in regions associated with executive and attentional processes that may mediate chunking processes to accommodate STM capacity (...) limits. (shrink)

It is argued that a mental integration is formed only if the result is a functional whole. This idea is then used to clarify the definition of a concept and discuss problems in which an instance may belong to different conceptual classes depending on the context. The same idea is also applied to the rules for dealing with an entity when it is formed out of sub-entities. Specific examples of how such rules are frequently violated in literature as well (...) as colloquially are discussed. (shrink)

ContextPeople with mental disorders can acquire long-term disabilities, which could impair their functioning and quality of life (QoL), requiring permanent care and social support. Systematic data on QoL and functioning, which could support a better management of these people, were not available.ObjectiveTo analyze the QoL, level of functioning and their association with sociodemographic and clinical factors of people with mental disorders who underwent deinstitutionalization using assisted living facilities.MethodsA Cross-sectional study was conducted between July 2018 and July 2019, through (...) interviews using the World Health Organization Quality of Life (WHOQOL-BREF) to determine the QoL scores, and the World Health Organization Disability Assessment Schedule (WHODAS 2.0) to determine the level of functioning. All adults (≥18 years old) with mental disorders, who underwent deinstitutionalization, users of assisted living facilities and assisted by the Psychosocial Assistance Centers III, in a city in the state of São Paulo, Brazil, were selected. For statistical analysis of the associated factors, Student’st-test was used for dichotomous variables and ANOVA for polynomial variables. Pearson correlation coefficient was used to measure the association between QoL and functioning scores.ResultsOut of 359 people who underwent deinstitutionalization with mental disorders, 147 met the eligibility criteria. The mean total score for the WHOQOL-BREF was 66.5 ± 13.4 and the mean score for WHODAS 2.0 was 10.4 ± 7.6. An association was found between people who were studying (n= 65.8; 95%CI, 63.5–68.1vs. n= 73.9; 95%CI, 67.5–80.3;p= 0.04) and better WHOQOL-BREF QoL scores or WHODAS 2.0 levels of functioning (n= 10.9; 95%CI, 9.6–12.2vs. n= 5.1; 95%CI, 2.5–7.7;p= 0.01). A weak negative correlation (r= 0.41) emerged between higher QoL scores and functioning improvement.ConclusionThis study indicates that the QoL of the sample is associated by their functioning levels, which, in turn, may reflect on their social interactions. Public policies that favor interventions increasing socialization of this population can result in better health outcomes. The QoL and functioning scores provide valuable insights to develop public policies more suited to this population profile. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:Changing Functions, Moral Responsibility, and Mental IllnessCraig Edwards (bio)Keywordsmental illness, responsibility, character, dysfunction, personhoodI thank both Wakefield and Tomasini for their illuminating comments. Both commentaries are thought provoking and warrant a full response. However, as always, space is limited and I must make the all-too-predictable apology for not addressing both commentaries in full. Wakefield's contribution more directly engages with, and challenges, my claims, and so I focus (...) on addressing his concerns.ClarificationsWakefield correctly notes that I am interested in how mental illness (and illness generally) operates to remove moral responsibility for one's actions. Despite this, it seems at several points that he and I are talking about two different, albeit related, concepts of mental illness. 'Mental illness' is used to both explain and excuse certain behaviors, but these two functions, explanatory and exculpable, do not always operate simultaneously. As we discover biological explanations for apparently immoral behaviors, the question arises as to whether the explanation should remove the immorality and liability for punishment. The 'sick role' can be divided into two aspects. One is the role of deserving and warranting medical treatment. The other is the negation of moral responsibility. Wakefield's own example, pedophilia, involves the first sense of the sick role but not the second. Wakefield's use of this example is unusual, because it deftly highlights the limitation of his HD account. Pedophilia is a mental disorder in the sense of warranting treatment, and is a mental illness under Wakefield's model, but it is not something that negates moral responsibility. There is a sense of the term 'mental illness'—an important and, as I argue, an objective sense—that is relevant to establishing one's moral responsibility for such behaviors.In addressing my account of mental illness as though it contained two distinct answers, 'mental illness as dysfunction of rational agency, or 'mental illness as moral judgment,' it is unclear whether Wakefield takes them to be conjunctive or alternative. Hence it is worth reiterating in point form the structure of my account:1. Illness involves dysfunction;2. The 'proper function' of a bodily or psychological mechanism is determined by the purpose that we impose upon that mechanism (within the constraints of our biological needs);3. Dysfunction of rational agency is necessary, but not sufficient, for 'mental illness' in the normative sense relevant to negating moral responsibility; and [End Page 105]4. The distinction between 'mental illness' (in the above sense) and the many dysfunctions of rational agency for which we are morally responsible, turns upon (objective) normative facts rather than features internal to the dysfunctions themselves.Functions and ValueWakefield misses the point when he criticizes my comment that, although bodily mechanisms are fairly uniformly valued, there is substantial historical and cross-cultural variation in the way people value personhood. He notes—accurately, but irrelevantly—that people almost always place great value on their capacity for rational agency, probably more so than many aspects of their physical health. My comment, taken in context, has nothing to do with how much people value personhood, but has everything to do with what kinds of purposes people want their mental and physical processes to achieve. A heart has the same function for a Londoner today as it did for a Japanese peasant a thousand years ago, and although it is possible for us to want it to achieve other purposes, any culture that seriously imputes a different set of vital functions on the heart is likely to be rather disappointed. By contrast, our species has experienced vast changes in the demands we make of our rational and intellectual capacities—dysfunctions like dyslexia and alcoholism were irrelevant before the availability of written communication and alcohol.Wakefield's HD account is unable to deal with the relevance of such change. The link between evolutionary function and illness is tenuous in any event. Evolutionary explanations of specific mechanisms are often untestable, simply positing some evolutionary purpose that happens to fit our understanding of what the mechanism does. If we were to discover that alcoholism evolved as a means of increasing birthrates, or (perhaps more plausibly) that anxiety disorders occur among those for whom... (shrink)