Although the role of emotion in socioeconomic decision making is increasingly recognised, the impact of specific emotional disorders, such as anxiety disorders, on these decisions has been surprisingly neglected. Twenty anxious patients and twenty matched controls completed a commonly used socioeconomic task (the Ultimatum Game), in which they had to accept or reject monetary offers from other players. Anxious patients accepted significantly more unfair offers than controls. We discuss the implications of these findings in light of recent models of anxiety, (...) in particular the importance of interpersonal factors and assertiveness in an integrated model of decision making. Finally, we were able to show that pharmacological serotonin used to treat anxious symptomatology tended to normalise decision making, further confirming and extending the role of serotonin in co-operation, prosocial behaviour, and social decision making. These results show, for the first time, a different pattern of socioeconomic behaviour in anxiety disordered patients, in addition to the known memory, attentional and emotional biases that are part of this pathological condition. (shrink)

It now seems technically feasible to culture human embryos beyond the “fourteen‐day limit,” which has the potential to increase scientific understanding of human development and perhaps improve infertility treatments. The fourteen‐day limit was adopted as a compromise but subsequently has been considered an ethical line. Does it remain relevant in light of technological advances permitting embryo maturation beyond it? Should it be changed and, if so, how and why? What justifications would be necessary to expand the limit, particularly given that (...) doing so would violate some people's moral commitments regarding human embryos? Robust stakeholder engagement preceded adoption of the fourteen‐day limit and should arguably be part of efforts to reassess it. Such engagement could also consider the need for enhanced oversight of human embryo research. In the meantime, developing and implementing reliable oversight systems should help foster high‐quality research and public confidence in it. (shrink)

It now seems technically feasible to culture human embryos beyond the “fourteen‐day limit,” which has the potential to increase scientific understanding of human development and perhaps improve infertility treatments. The fourteen‐day limit was adopted as a compromise but subsequently has been considered an ethical line. Does it remain relevant in light of technological advances permitting embryo maturation beyond it? Should it be changed and, if so, how and why? What justifications would be necessary to expand the limit, particularly given that (...) doing so would violate some people's moral commitments regarding human embryos? Robust stakeholder engagement preceded adoption of the fourteen‐day limit and should arguably be part of efforts to reassess it. Such engagement could also consider the need for enhanced oversight of human embryo research. In the meantime, developing and implementing reliable oversight systems should help foster high‐quality research and public confidence in it. (shrink)

We design a framework for assisted normative reasoning based on Aristotelian diagrams and algorithmic graph theory which can be employed to address heterogeneous tasks of deductive reasoning. Here we focus on two problems of normative determination: we show that the algorithms used to address these problems are computationally efficient and their operations are traceable by humans. Finally, we discuss an application of our framework to a scenario regulated by the GDPR.

Teaching business ethics effectively may prepare future leaders and managers to better deal with delicate situations that they might face in the workplace. However, such an aim is one of the biggest challenges that educators at universities are called on to solve. An increasing number of scholars are invoking the role of prudence in the virtue ethics context as a viable approach to teach students how to manage ethical dilemmas. In this regard, this paper discusses the “St. Albans Family Enterprises” (...) case study that can serve as an instrument to help students and practitioners develop their ethical decision-making ability and to foster a disposition towards applying sound judgment or what can be called in classical terms, prudence. The teaching note that accompanies the case study offers guidance to educators about how the case can be used for teaching purposes, and explains the implications of exercising practical wisdom within a virtue ethics framework. (shrink)

This paper puts forward the hypothesis that the distinctive features of quantum statistics are exclusively determined by the nature of the properties it describes. In particular, all statistically relevant properties of identical quantum particles in many-particle systems are conjectured to be irreducible, ‘inherent’ properties only belonging to the whole system. This allows one to explain quantum statistics without endorsing the ‘Received View’ that particles are non-individuals, or postulating that quantum systems obey peculiar probability distributions, or assuming that there are primitive (...) restrictions on the range of states accessible to such systems. With this, the need for an unambiguously metaphysical explanation of certain physical facts is acknowledged and satisfied. (shrink)

Although theoretical underpinnings of stakeholder dialog (SD) have been extensively discussed in the extant literature, there is a lack of empirical studies presenting evidence on the SD initiatives undertaken by firms. In this article, we provide information about 294 SD initiatives collected through a content analysis of the sustainability reports published by large firms in Germany, Italy, and the U. S. In addition to a country-based description of the different forms, stakeholder categories, and topics of the SD initiatives, we explore (...) the relationship between SD and characteristics of national business systems. Overall, we find firms undertake few SD initiatives, using low-involvement forms of dialog, and focusing on one category of stakeholders per initiative. Results suggest that the explicit approach to corporate social responsibility (CSR) favors the quantity of SD initiatives, but neglects the importance of the level of involvement and diversity of stakeholders participating at the dialog. Finally, we find public policies on CSR have a substantial influence on SD in national business systems with an implicit approach to CSR. Public policies based on a shared discussion involving multiple social actors encourage SD initiatives that use different forms of dialog and are characterized by high level of involvement. Our findings offer contributions to the ongoing debate about the effectiveness of SD and its relationship with CSR. (shrink)

According to the received view of evolution, only genes are inherited. From this view it follows that only genetically-caused phenotypic variation is selectable and, thereby, that all selection is at bottom genetic selection. This paper argues that the received view is wrong. In many species, there are intergenerationally-stable phenotypic differences due to environmental differences. Natural selection can act on these nongenetically-caused phenotypic differences in the same way it acts on genetically-caused phenotypic differences. Some selection is at bottom nongenetic selection. The (...) argument against the received view involves a reformulation of the concepts of inheritance and heritability. Inherited factors are all those developmental factors responsible for parent–offspring similarity; some inherited factors are genetic and some are not. Heritable variation is intergenerationally-stable phenotypic variation; some such variation is genetically-caused and some is not. The received view and its critics The possibility of nongenetic selection (the lucky butterfly) The reality of nongenetic selection 3.1 Imprinting mechanisms 3.2 Other learning mechanisms 3.3 Other nongenetic mechanisms Genetic and nongenetic inheritance mechanisms Genetic and nongenetic inherited factors Genetic and nongenetic heritability Conclusions + Current address: Dr Matteo Mameli, Research Fellow, King's College, Cambridge, CB2 1ST, United Kingdom, matteo.mameli{at}kings.cam.ac.uk' + u + '@' + d + ''//-->. (shrink)

In this paper, we develop an organizational account that defines biological functions as causal relations subject to closure in living systems, interpreted as the most typical example of organizationally closed and differentiated self-maintaining systems. We argue that this account adequately grounds the teleological and normative dimensions of functions in the current organization of a system, insofar as it provides an explanation for the existence of the function bearer and, at the same time, identifies in a non-arbitrary way the norms that (...) functions are supposed to obey. Accordingly, we suggest that the organizational account combines the etiological and dispositional perspectives in an integrated theoretical framework. IntroductionDispositional ApproachesEtiological TheoriesBiological Self-maintenance Closure, teleology, and normativityOrganizational differentiationFunctions C1: Contributing to the maintenance of the organization C2: Producing the functional trait Implications and Objections Functional versus useful Dysfunctions, side effects, and accidental contributionsProper functions and selected effectsReproductionRelation with other ‘unitarian’ approachesConclusions. (shrink)

Formal series are associated with ascriptions of numbers. They are ordered by formal operations that, unlike negation and disjunction, are not truth-operations. In spite of this, they are required to build propositions involving generic reference to numbers, and are essential to the Tractarian version of the logicist project.

This paper provides a defence of the account of partial resemblances between properties according to which such resemblances are due to partial identities of constituent properties. It is argued, first of all, that the account is not only required by realists about universals à la Armstrong, but also useful (of course, in an appropriately re-formulated form) for those who prefer a nominalistic ontology for material objects. For this reason, the paper only briefly considers the problem of how to conceive of (...) the structural universals first posited by Armstrong in order to explain partial resemblances, and focuses instead on criticisms that have been levelled against the theory (by Pautz, Eddon, Denkel and Gibb) and that apply regardless of one’s preferred ontological framework. The partial identity account is defended from these objections and, in doing so, a hitherto quite neglected connection—between the debate about partial similarity as partial identity and that concerning ontological finitism versus infinitism—is looked at in some detail. (shrink)

Some naturalistic philosophers of mind subscribing to the predictive processing theory of mind have adopted a realist attitude towards the results of Bayesian cognitive science. In this paper, we argue that this realist attitude is unwarranted. The Bayesian research program in cognitive science does not possess special epistemic virtues over alternative approaches for explaining mental phenomena involving uncertainty. In particular, the Bayesian approach is not simpler, more unifying, or more rational than alternatives. It is also contentious that the Bayesian approach (...) is overall better supported by the empirical evidence. So, to develop philosophical theories of mind on the basis of a realist interpretation of results from Bayesian cognitive science is unwarranted. Naturalistic philosophers of mind should instead adopt an anti-realist attitude towards these results and remain agnostic as to whether Bayesian models are true. For continuing on with an exclusive focus and praise of Bayes within debates about the predictive processing theory will impede progress in philosophical understanding of scientific practice in computational cognitive science as well as of the architecture of the mind. (shrink)

Entry of the Encyclopedia of Systems Biology.

Les Remarques philosophiques sont la première tentative de mettre en oeuvre le programme qui découle de l’échec du projet du Tractatus Logico-Philosophicus. Le noyau de ce programme est donné par l’abandon de l’analyse des nombres avancée dans le Tractatus. Wittgenstein se rend compte que les nombres doivent se trouver à la base même du langage, dans la structure des propositions élémentaires. En même temps, il se rend compte qu’il est impossible de fournir la logique sousjacente au langage avant d’avoir procédé (...) à l’analyse. Le projet d’une investigation logique des phénomènes s’imposait, donc, même après l’abandon de l’idée d’un langage phénoménologique. The Philosophical Remarks is a first attempt at pursuing the philosophical agenda determined by the failure of the Tractarian project. The central point of this agenda is the abandonment of the analysis of number that had been given in the Tractatus. Wittgenstein realizes that numbers should be brought back to the basis of language, as part of the structure of the elementary propositions themselves. At the same time, he realizes that it is impossible to give the logic underlying our language before the process of logical analysis is carried out. He undertakes the project of a logical investigation of phenomena even after giving up the idea of a phenomenological language. (shrink)

This paper argues that biological organisation can be legitimately conceived of as an intrinsically teleological causal regime. The core of the argument consists in establishing a connection between organisation and teleology through the concept of self-determination: biological organisation determines itself in the sense that the effects of its activity contribute to determine its own conditions of existence. We suggest that not any kind of circular regime realises self-determination, which should be specifically understood as self-constraint: in biological systems, in particular, self-constraint (...) takes the form of closure, i.e. a network of mutually dependent constitutive constraints. We then explore the occurrence of intrinsic teleology in the biological domain and beyond. On the one hand, the organisational account might possibly concede that supra-organismal biological systems could realise closure, and hence be teleological. On the other hand, the realisation of closure beyond the biological realm appears to be highly unlikely. In turn, the occurrence of simpler forms of self-determination remains a controversial issue, in particular with respect to the case of self-organising dissipative systems. (shrink)

This paper brings together results from the philosophy and the psychology of explanation to argue that there are multiple concepts of explanation in human psychology. Specifically, it is shown that pluralism about explanation coheres with the multiplicity of models of explanation available in the philosophy of science, and it is supported by evidence from the psychology of explanatory judgment. Focusing on the case of a norm of explanatory power, the paper concludes by responding to the worry that if there is (...) a plurality of concepts of explanation, one will not be able to normatively evaluate what counts as good explanation. (shrink)

We analyze the notion of guessing model, a way to assign combinatorial properties to arbitrary regular cardinals. Guessing models can be used, in combination with inaccessibility, to characterize various large cardinal axioms, ranging from supercompactness to rank-to-rank embeddings. The majority of these large cardinal properties can be defined in terms of suitable elementary embeddings j:Vγ→Vλ. One key observation is that such embeddings are uniquely determined by the image structures j[Vγ]≺Vλ. These structures will be the prototypes guessing models. We shall show, (...) using guessing models M, how to prove for the ordinal κM=jM) many of the combinatorial properties that we can prove for the cardinal j) using the structure j[Vγ]≺Vj. κM will always be a regular cardinal, but consistently can be a successor and guessing models M with κM=ℵ2 exist assuming the proper forcing axiom. By means of these models we shall introduce a new structural property of models of PFA: the existence of a “Laver function” f:ℵ2→Hℵ2 sharing the same features of the usual Laver functions f:κ→Hκ provided by a supercompact cardinal κ. Further applications of our analysis will be proofs of the singular cardinal hypothesis and of the failure of the square principle assuming the existence of guessing models. In particular the failure of square shows that the existence of guessing models is a very strong assumption in terms of large cardinal strength. (shrink)

Conf(l)essioni conclude l'itinerario in quattro tappe dedicato all'operazione del pensare. Giunge ora la morale, che, in queste Conf(l)essioni, illustra che cosa il pensiero possa donare all’esistenza del pensatore.

Les Remarques philosophiques sont la première tentative de mettre en oeuvre le programme qui découle de l’échec du projet du Tractatus Logico-Philosophicus. Le noyau de ce programme est donné par l’abandon de l’analyse des nombres avancée dans le Tractatus. Wittgenstein se rend compte que les nombres doivent se trouver à la base même du langage, dans la structure des propositions élémentaires. En même temps, il se rend compte qu’il est impossible de fournir la logique sousjacente au langage avant d’avoir procédé (...) à l’analyse. Le projet d’une investigation logique des phénomènes s’imposait, donc, même après l’abandon de l’idée d’un langage phénoménologique. The Philosophical Remarks is a first attempt at pursuing the philosophical agenda determined by the failure of the Tractarian project. The central point of this agenda is the abandonment of the analysis of number that had been given in the Tractatus. Wittgenstein realizes that numbers should be brought back to the basis of language, as part of the structure of the elementary propositions themselves. At the same time, he realizes that it is impossible to give the logic underlying our language before the process of logical analysis is carried out. He undertakes the project of a logical investigation of phenomena even after giving up the idea of a phenomenological language. (shrink)

We develop a conceptual framework that connects biological heredity and organization. We refer to heredity as the cross-generation conservation of functional elements, defined as constraints subject to organizational closure. While hereditary objects are functional constituents of biological systems, any other entity that is stable across generations—and possibly involved in the recurrence of phenotypes—belongs to their environment. The central outcome of the organizational perspective consists in extending the scope of heredity beyond the genetic domain without merging it with the broad category (...) of cross-generation stability. After discussing some implications, we conclude with a reflection on the relationship between stability and variation. 1Introduction2From Extended Heredity to Cross-generation Stability 2.1Extending the scope of heredity: A brief state of the art2.2Rethinking heredity: Conceptual challenges3Biological Heredity in Light of Organization 3.1Biological organization within organisms and beyond3.2Extending organization in time3.3What is biological heredity?4Implications and Objections 4.1Heredity as a specific kind of cross-generation stability4.2Heredity at various levels of description4.3Non-functional and dysfunctional objects5Conclusions: From Conservation to Variation. (shrink)

Some authors have argued that the human use of reproductive cloning and genetic engineering should be prohibited because these biotechnologies would undermine the autonomy of the resulting child. In this paper, two versions of this view are discussed. According to the first version, the autonomy of cloned and genetically engineered people would be undermined because knowledge of the method by which these people have been conceived would make them unable to assume full responsibility for their actions. According to the second (...) version, these biotechnologies would undermine autonomy by violating these people’s right to an open future. There is no evidence to show that people conceived through cloning and genetic engineering would inevitably or even in general be unable to assume responsibility for their actions; there is also no evidence for the claim that cloning and genetic engineering would inevitably or even in general rob the child of the possibility to choose from a sufficiently large array of life plans. (shrink)

On the occasion of the almost contemporary publication of two interesting books on Thomas Paine, SCIENZA & POLITICA has addressed the two authors – Matteo Battistini and Maurizio Griffo – with some questions about the different approaches of their works. The result is a long-distance dialogue, which explores not only the significance of the American revolutionary and constitutional events, but also the influence that the English legacy and the French revolutionary experience have exercised on the American political thinker. A (...) Tale of Two Paines handles the problem of its attribution either to liberalism or to democratic radicalism; it also faces the preoccupation with the defence of liberty in the historical reconstruction of the State in the light of the affirmation of the sovereignty of society. (shrink)

Current explanatory frameworks for social norms pay little attention to why and how brains might carry out computational functions that generate norm compliance behavior. This paper expands on existing literature by laying out the beginnings of a neurocomputational framework for social norms and social cognition, which can be the basis for advancing our understanding of the nature and mechanisms of social norms. Two neurocomputational building blocks are identified that might constitute the core of the mechanism of norm compliance. They consist (...) of Bayesian and reinforcement learning systems. It is sketched why and how the concerted activity of these systems can generate norm compliance by minimization of three specific kinds of prediction-errors. (shrink)

The present paper discusses different approaches to metaphysics and defends a specific, non-deflationary approach that nevertheless qualifies as scientifically-grounded and, consequently, as acceptable from the naturalistic viewpoint. By critically assessing some recent work on science and metaphysics, we argue that such a sophisticated form of naturalism, which preserves the autonomy of metaphysics as an a priori enterprise yet pays due attention to the indications coming from our best science, is not only workable but recommended.

Mathematical platonism is the view that abstract mathematical objects exist. Ontological pluralism is the view that there are many modes of existence. This paper examines the prospects for...

This article provides a much-needed introduction to the philosophical debates around nihilism and negative thought which preoccupied many Italian left intellectuals in the seventies, and which still have important repercussions today. In order to present the principal stakes of the ‘Left Heideggerian’ current, the article undertakes a close reading of Massimo Cacciari’s 1976 book Krisis, and of Antonio Negri’s critical response to it—first in a review of the book, and then in a number of texts from the seventies and eighties, (...) closely analysed by Mandarini, in which Negri develops a positive political metaphysics. This contrast between Cacciari and Negri allows Mandarini to investigate the significance of seemingly recondite philosophical issues to the development of Italian radical political thought, and to identify some of the key stakes of this debate: the status of politics and the political, the role of ontology, the place of dialectics and, crucially, the opposition between Cacciari’s formalistic understanding of negativity and Negri’s link between negativity and antagonism. (shrink)

Science and philosophy both express, and attempt to quench, the distinctively human thirst for knowledge. Today, their mutual relationship has become one of conflict or indifference rather than cooperation. At the same time, scientists and philosophers alike have moved away from at least some of our ordinary beliefs. But what can scientific and philosophical theories tell us about the world, in isolation from each other? And to what extent does a sophisticated investigation into the nature of things force us to (...) question commonsense beliefs? This book defends a form of naturalism which preserves the autonomy of metaphysics – the part of philosophy that aims to uncover the fundamental features of reality - while also keeping science centre stage. The proposed methodological perspective allows one to seek the right equilibrium between science, metaphysics and common sense. This is illustrated via three case studies, which provide a clear discussion of key philosophical issues. (shrink)

Since the discovery of the double helical structure of DNA, the standard account of the inheritance of features has been in terms of DNA-copying and DNA-transmission. This theory is just a version of the old theory according to which the inheritance of features is explained by the transfer at conception of some developmentally privileged material from parents to offspring. This paper does the following things: (1) it explains what the inheritance of features is; (2) it explains how the DNA-centric theory (...) emerged; (3) it clarifies the relation between the DNA-centric theory and the ‘unfolding’ theory of development; (4) it argues that (given what we now know about developmental processes and genetic activity) the DNA-centric theory should be abandoned in favour of a pluralistic (but not holistic) theory of the inheritance of features. According to this pluralistic theory, the reliable reoccurrence of phenotypes must be explained by appealing not only to processes responsible for the reliable reoccurrence of genetic developmental factors but also to processes responsible for the reliable reoccurrence (or persistence) of nongenetic developmental factors. (shrink)

This paper investigates the ethical issues surrounding the concept of Internet neutrality focusing specifically on the correlation between neutrality and fairness. Moving from an analysis of the many available definitions of Internet neutrality and the heterogeneity of the Internet infrastructure, the common assumption that a neutral Internet is also a fair Internet is challenged. It is argued that a properly neutral Internet supports undesirable situations in which few users can exhaust the majority of the available resources or in which specific (...) types of applications and services cannot be developed or properly deployed. The solution offered to these shortcomings is based on (1) an environmental approach to the Internet, (2) the four guiding principles of Floridi’s Information Ethics and (3) a principle called ‘Information Diversity’. The paper is divided into six sections. Section 1 briefly presents the debate concerning the concepts of network and Internet neutrality. Section 2 poses a general and unifying definition of Internet neutrality based on the critical assessment of several domain-specific approaches to the problem of neutrality. Section 3 is dedicated to the analysis of the relationship between Internet neutrality and the ethical principle of fairness. Section 4 introduces Floridi’s Information Ethics, the definition of Information Diversity and an analysis of how they can be used to address the limitations of Internet neutrality. Section 5 summarises the ethics of Internet neutrality and Information Diversity defining their relationship. Section 6 reviews the arguments presented in the paper clarifying the foundational role played by Information Diversity and Information Ethics in Internet policy-making activity. (shrink)

Letheby’s "Philosophy of Psychedelics" relies on Predictive Processing to try and find unifying explanations relevant to understanding how serotonergic psychedelics work in psychiatric therapy, what subjective experiences are associated with their use and whether such experiences are epistemically defective. But if Predictive Processing lacks genuinely explanatory unifying power, Letheby’s account of psychedelic therapy risks being unwarranted. In this commentary, I motivate this worry and sketch an alternative interpretation of psychedelic therapy within the Reinforcement Learning framework.

As innovations in the field of vascular composite allotransplantation (VCA) progress, whole-eye transplantation (WET) is poised to transition from non-human mammalian models to living human recipients. Present treatment options for vision loss are generally considered suboptimal, and attendant concerns ranging from aesthetics and prosthesis maintenance to social stigma may be mitigated by WET. Potential benefits to WET recipients may also include partial vision restoration, psychosocial benefits related to identity and social integration, improvements in physical comfort and function, and reduced surgical (...) risk associated with a biologic eye compared to a prosthesis. Perioperative and postoperative risks of WET are expected to be comparable to those of facial transplantation (FT), and may be similarly mitigated by immunosuppressive protocols, adequate psychosocial support, and a thorough selection process for both the recipient and donor. To minimize the risks associated with immunosuppressive medications, the first attempts in human recipients will likely be performed in conjunction with a FT. If first-in-human attempts at combined FT-WET prove successful and the biologic eye survives, this opens the door for further advancement in the field of vision restoration by means of a viable surgical option. This analysis integrates recent innovations in WET research with the existing discourse on the ethics of surgical innovation and offers preliminary guidance to VCA programs considering undertaking WET in human recipients. (shrink)

Can facts about subpersonal states and events be constitutively relevant to personal-level phenomena? And can knowledge of these facts inform explanations of personal-level phenomena? Some philosophers, like Jennifer Hornsby and John McDowell, argue for two negative answers whereby questions about persons and their behavior cannot be answered by using information from subpersonal psychology. Knowledge of subpersonal states and events cannot inform personal-level explanation such that they cast light on what constitutes persons? behaviors. In this paper I argue against this position. (...) After having distinguished between enabling and constitutive relevance, I defend the claim that at least some facts about subpersonal states and events are constitutively relevant to some personal-level phenomenon, and therefore can, and sometimes should, inform personal-level explanations. I draw some of the possible consequences of my claim for our understanding of personal-level behavior by focusing on the phenomenon of addiction. (shrink)

The idea of an unchanging human nature has always had a special place in Western philosophical thought. Far from being uncontested, this idea has received criticism from different traditions of thought, which have seen it even as an obstacle to the understanding of ourselves. Now it appears in the shape of a renewed naturalism and the opposing forces are the same as in the past. This volume shows some lines of the current debate about human nature: the revival of Herodotus (...) and Protagoras's humanistic relativism and tolerance; Darwinian ethics; the critical relationship between neo-Aristotelian and neo-Kantian moral theories and the results of empirical science; the assumption about the existence of a “moral mind” based on an innate moral grammar; the multicultural political debate which considers the idea of human nature as a product and a tool of Western hegemony; and, finally, the reflection on sex and gender in the theory of difference and on the idea of "living" nature in the contemporary biopolitics. (shrink)

Falando do ponto de vista da eternidade, Meister Eckhart era totalmente alheio ao milenarismo. No evento sempre renovado do nascimento do logos no fundo da alma, o tempo para o turíngio deixa de existir. A mística eckhartiana, ultrapassando a contraposição entre “místico” e “intelectual”, revela seus fundamentos filosófico-intelectualistas na afinidade com o pensamento neoplatônico e seu elo com os movimentos populares do Outono da Idade Média.

After the Second World War, Italy experienced an economic miracle accompanied by the emergence of a material culture highly dense with meaning. This article adopts a second-order approach, which focuses on two concepts that emphasize the component of invention contained within the innovation process.Garboindicates the peculiarly Italian way of solving a constrained optimization problem in the design of everyday objects. Meanwhile, the concept ofcenacolo– whose etymological roots indicate conviviality and good living – made possible the study of the peculiar social (...) networks of the Milanese cultural landscape during the 1960s, which enabled important cross-fertilizations between industry, culture and art. To demonstrate the connections between invention andgarboandcenacoli, the examples of Olivetti (key player in then-nascent personal computer technology) and Bialetti (producer of the Moka coffee machine) are used as case studies of innovative solutions to constrained problems. Following an outline of elements promoting the success of each, the article identifies historically determined mechanisms, which enable us to imagine and (potentially) establish the evolutionary conditions for new pathways of invention. (shrink)