Although the role of emotion in socioeconomic decision making is increasingly recognised, the impact of specific emotional disorders, such as anxiety disorders, on these decisions has been surprisingly neglected. Twenty anxious patients and twenty matched controls completed a commonly used socioeconomic task (the Ultimatum Game), in which they had to accept or reject monetary offers from other players. Anxious patients accepted significantly more unfair offers than controls. We discuss the implications of these findings in light of recent models of anxiety, (...) in particular the importance of interpersonal factors and assertiveness in an integrated model of decision making. Finally, we were able to show that pharmacological serotonin used to treat anxious symptomatology tended to normalise decision making, further confirming and extending the role of serotonin in co-operation, prosocial behaviour, and social decision making. These results show, for the first time, a different pattern of socioeconomic behaviour in anxiety disordered patients, in addition to the known memory, attentional and emotional biases that are part of this pathological condition. (shrink)

This paper is dedicated to extending and adapting to modal logic the approach of fractional semantics to classical logic. This is a multi-valued semantics governed by pure proof-theoretic considerations, whose truth-values are the rational numbers in the closed interval $[0,1]$. Focusing on the modal logic K, the proposed methodology relies on three key components: bilateral sequent calculus, invertibility of the logical rules, and stability (proof-invariance). We show that our semantic analysis of K affords an informational refinement with respect to the (...) standard Kripkean semantics (a new proof of Dugundji’s theorem is a case in point) and it raises the prospect of a proof-theoretic semantics for modal logic. (shrink)

It now seems technically feasible to culture human embryos beyond the “fourteen‐day limit,” which has the potential to increase scientific understanding of human development and perhaps improve infertility treatments. The fourteen‐day limit was adopted as a compromise but subsequently has been considered an ethical line. Does it remain relevant in light of technological advances permitting embryo maturation beyond it? Should it be changed and, if so, how and why? What justifications would be necessary to expand the limit, particularly given that (...) doing so would violate some people's moral commitments regarding human embryos? Robust stakeholder engagement preceded adoption of the fourteen‐day limit and should arguably be part of efforts to reassess it. Such engagement could also consider the need for enhanced oversight of human embryo research. In the meantime, developing and implementing reliable oversight systems should help foster high‐quality research and public confidence in it. (shrink)

It now seems technically feasible to culture human embryos beyond the “fourteen‐day limit,” which has the potential to increase scientific understanding of human development and perhaps improve infertility treatments. The fourteen‐day limit was adopted as a compromise but subsequently has been considered an ethical line. Does it remain relevant in light of technological advances permitting embryo maturation beyond it? Should it be changed and, if so, how and why? What justifications would be necessary to expand the limit, particularly given that (...) doing so would violate some people's moral commitments regarding human embryos? Robust stakeholder engagement preceded adoption of the fourteen‐day limit and should arguably be part of efforts to reassess it. Such engagement could also consider the need for enhanced oversight of human embryo research. In the meantime, developing and implementing reliable oversight systems should help foster high‐quality research and public confidence in it. (shrink)

We design a framework for assisted normative reasoning based on Aristotelian diagrams and algorithmic graph theory which can be employed to address heterogeneous tasks of deductive reasoning. Here we focus on two problems of normative determination: we show that the algorithms used to address these problems are computationally efficient and their operations are traceable by humans. Finally, we discuss an application of our framework to a scenario regulated by the GDPR.

This paper puts forward the hypothesis that the distinctive features of quantum statistics are exclusively determined by the nature of the properties it describes. In particular, all statistically relevant properties of identical quantum particles in many-particle systems are conjectured to be irreducible, ‘inherent’ properties only belonging to the whole system. This allows one to explain quantum statistics without endorsing the ‘Received View’ that particles are non-individuals, or postulating that quantum systems obey peculiar probability distributions, or assuming that there are primitive (...) restrictions on the range of states accessible to such systems. With this, the need for an unambiguously metaphysical explanation of certain physical facts is acknowledged and satisfied. (shrink)

In a recent paper, under the auspices of an unorthodox variety of bilateralism, we introduced a new kind of proof-theoretic semantics for the base modal logic \(\mathbf{K}\), whose values lie in the closed interval \([0,1]\) of rational numbers [14]. In this paper, after clarifying our conception of bilateralism – dubbed “soft bilateralism” – we generalize the fractional method to encompass extensions and weakenings of \(\mathbf{K}\). Specifically, we introduce well-behaved hypersequent calculi for the deontic logic \(\mathbf{D}\) and the non-normal modal logics (...) \(\mathbf{E}\) and \(\mathbf{M}\) and thoroughly investigate their structural properties. (shrink)

According to the received view of evolution, only genes are inherited. From this view it follows that only genetically-caused phenotypic variation is selectable and, thereby, that all selection is at bottom genetic selection. This paper argues that the received view is wrong. In many species, there are intergenerationally-stable phenotypic differences due to environmental differences. Natural selection can act on these nongenetically-caused phenotypic differences in the same way it acts on genetically-caused phenotypic differences. Some selection is at bottom nongenetic selection. The (...) argument against the received view involves a reformulation of the concepts of inheritance and heritability. Inherited factors are all those developmental factors responsible for parent–offspring similarity; some inherited factors are genetic and some are not. Heritable variation is intergenerationally-stable phenotypic variation; some such variation is genetically-caused and some is not. The received view and its critics The possibility of nongenetic selection (the lucky butterfly) The reality of nongenetic selection 3.1 Imprinting mechanisms 3.2 Other learning mechanisms 3.3 Other nongenetic mechanisms Genetic and nongenetic inheritance mechanisms Genetic and nongenetic inherited factors Genetic and nongenetic heritability Conclusions + Current address: Dr Matteo Mameli, Research Fellow, King's College, Cambridge, CB2 1ST, United Kingdom, matteo.mameli{at}kings.cam.ac.uk' + u + '@' + d + ''//-->. (shrink)

Although theoretical underpinnings of stakeholder dialog (SD) have been extensively discussed in the extant literature, there is a lack of empirical studies presenting evidence on the SD initiatives undertaken by firms. In this article, we provide information about 294 SD initiatives collected through a content analysis of the sustainability reports published by large firms in Germany, Italy, and the U. S. In addition to a country-based description of the different forms, stakeholder categories, and topics of the SD initiatives, we explore (...) the relationship between SD and characteristics of national business systems. Overall, we find firms undertake few SD initiatives, using low-involvement forms of dialog, and focusing on one category of stakeholders per initiative. Results suggest that the explicit approach to corporate social responsibility (CSR) favors the quantity of SD initiatives, but neglects the importance of the level of involvement and diversity of stakeholders participating at the dialog. Finally, we find public policies on CSR have a substantial influence on SD in national business systems with an implicit approach to CSR. Public policies based on a shared discussion involving multiple social actors encourage SD initiatives that use different forms of dialog and are characterized by high level of involvement. Our findings offer contributions to the ongoing debate about the effectiveness of SD and its relationship with CSR. (shrink)

This paper provides a defence of the account of partial resemblances between properties according to which such resemblances are due to partial identities of constituent properties. It is argued, first of all, that the account is not only required by realists about universals à la Armstrong, but also useful (of course, in an appropriately re-formulated form) for those who prefer a nominalistic ontology for material objects. For this reason, the paper only briefly considers the problem of how to conceive of (...) the structural universals first posited by Armstrong in order to explain partial resemblances, and focuses instead on criticisms that have been levelled against the theory (by Pautz, Eddon, Denkel and Gibb) and that apply regardless of one’s preferred ontological framework. The partial identity account is defended from these objections and, in doing so, a hitherto quite neglected connection—between the debate about partial similarity as partial identity and that concerning ontological finitism versus infinitism—is looked at in some detail. (shrink)

The notion of subject matter is a key concern of contemporary philosophy of language and logic. A central task for a theory of subject matter is to characterise the notion of sentential subject matter, that is, to assign to each sentence of a given language a subject matter that may count as its subject matter. In this paper, we elaborate upon David Lewis’ account of subject matter. Lewis’ proposal is simple and elegant but lacks a satisfactory characterisation of sentential subject (...) matter. Drawing on linguistic literature on focus and on the question under discussion, we offer a neo-Lewisian account of subject matter, which retains all the virtues of Lewis’ but also includes an attractive characterisation of sentential subject matter. (shrink)

In this paper, we develop an organizational account that defines biological functions as causal relations subject to closure in living systems, interpreted as the most typical example of organizationally closed and differentiated self-maintaining systems. We argue that this account adequately grounds the teleological and normative dimensions of functions in the current organization of a system, insofar as it provides an explanation for the existence of the function bearer and, at the same time, identifies in a non-arbitrary way the norms that (...) functions are supposed to obey. Accordingly, we suggest that the organizational account combines the etiological and dispositional perspectives in an integrated theoretical framework. IntroductionDispositional ApproachesEtiological TheoriesBiological Self-maintenance Closure, teleology, and normativityOrganizational differentiationFunctions C1: Contributing to the maintenance of the organization C2: Producing the functional trait Implications and Objections Functional versus useful Dysfunctions, side effects, and accidental contributionsProper functions and selected effectsReproductionRelation with other ‘unitarian’ approachesConclusions. (shrink)

Some naturalistic philosophers of mind subscribing to the predictive processing theory of mind have adopted a realist attitude towards the results of Bayesian cognitive science. In this paper, we argue that this realist attitude is unwarranted. The Bayesian research program in cognitive science does not possess special epistemic virtues over alternative approaches for explaining mental phenomena involving uncertainty. In particular, the Bayesian approach is not simpler, more unifying, or more rational than alternatives. It is also contentious that the Bayesian approach (...) is overall better supported by the empirical evidence. So, to develop philosophical theories of mind on the basis of a realist interpretation of results from Bayesian cognitive science is unwarranted. Naturalistic philosophers of mind should instead adopt an anti-realist attitude towards these results and remain agnostic as to whether Bayesian models are true. For continuing on with an exclusive focus and praise of Bayes within debates about the predictive processing theory will impede progress in philosophical understanding of scientific practice in computational cognitive science as well as of the architecture of the mind. (shrink)

Entry of the Encyclopedia of Systems Biology.

The free-energy principle states that all systems that minimize their free energy resist a tendency to physical disintegration. Originally proposed to account for perception, learning, and action, the free-energy principle has been applied to the evolution, development, morphology, anatomy and function of the brain, and has been called a postulate, an unfalsifiable principle, a natural law, and an imperative. While it might afford a theoretical foundation for understanding the relationship between environment, life, and mind, its epistemic status is unclear. Also (...) unclear is how the free-energy principle relates to prominent theoretical approaches to life science phenomena, such as organicism and mechanism. This paper clarifies both issues, and identifies limits and prospects for the free-energy principle as a first principle in the life sciences. (shrink)

C. I. Lewis’ systems were the first axiomatisations of modal logics. However some of those systems are non-normal modal logics, since they do not admit a full rule of necessitation, but only a restricted version thereof. We provide G3-style labelled sequent calculi for Lewis’ non-normal propositional systems. The calculi enjoy good structural properties, namely admissibility of structural rules and admissibility of cut. Furthermore they allow for straightforward proofs of admissibility of the restricted versions of the necessitation rule. We establish completeness (...) of the calculi and we discuss also related systems. (shrink)

Conf(l)essioni conclude l'itinerario in quattro tappe dedicato all'operazione del pensare. Giunge ora la morale, che, in queste Conf(l)essioni, illustra che cosa il pensiero possa donare all’esistenza del pensatore.

This paper argues that biological organisation can be legitimately conceived of as an intrinsically teleological causal regime. The core of the argument consists in establishing a connection between organisation and teleology through the concept of self-determination: biological organisation determines itself in the sense that the effects of its activity contribute to determine its own conditions of existence. We suggest that not any kind of circular regime realises self-determination, which should be specifically understood as self-constraint: in biological systems, in particular, self-constraint (...) takes the form of closure, i.e. a network of mutually dependent constitutive constraints. We then explore the occurrence of intrinsic teleology in the biological domain and beyond. On the one hand, the organisational account might possibly concede that supra-organismal biological systems could realise closure, and hence be teleological. On the other hand, the realisation of closure beyond the biological realm appears to be highly unlikely. In turn, the occurrence of simpler forms of self-determination remains a controversial issue, in particular with respect to the case of self-organising dissipative systems. (shrink)

On the occasion of the almost contemporary publication of two interesting books on Thomas Paine, SCIENZA & POLITICA has addressed the two authors – Matteo Battistini and Maurizio Griffo – with some questions about the different approaches of their works. The result is a long-distance dialogue, which explores not only the significance of the American revolutionary and constitutional events, but also the influence that the English legacy and the French revolutionary experience have exercised on the American political thinker. A (...) Tale of Two Paines handles the problem of its attribution either to liberalism or to democratic radicalism; it also faces the preoccupation with the defence of liberty in the historical reconstruction of the State in the light of the affirmation of the sovereignty of society. (shrink)

This paper brings together results from the philosophy and the psychology of explanation to argue that there are multiple concepts of explanation in human psychology. Specifically, it is shown that pluralism about explanation coheres with the multiplicity of models of explanation available in the philosophy of science, and it is supported by evidence from the psychology of explanatory judgment. Focusing on the case of a norm of explanatory power, the paper concludes by responding to the worry that if there is (...) a plurality of concepts of explanation, one will not be able to normatively evaluate what counts as good explanation. (shrink)

Current explanatory frameworks for social norms pay little attention to why and how brains might carry out computational functions that generate norm compliance behavior. This paper expands on existing literature by laying out the beginnings of a neurocomputational framework for social norms and social cognition, which can be the basis for advancing our understanding of the nature and mechanisms of social norms. Two neurocomputational building blocks are identified that might constitute the core of the mechanism of norm compliance. They consist (...) of Bayesian and reinforcement learning systems. It is sketched why and how the concerted activity of these systems can generate norm compliance by minimization of three specific kinds of prediction-errors. (shrink)

We develop a conceptual framework that connects biological heredity and organization. We refer to heredity as the cross-generation conservation of functional elements, defined as constraints subject to organizational closure. While hereditary objects are functional constituents of biological systems, any other entity that is stable across generations—and possibly involved in the recurrence of phenotypes—belongs to their environment. The central outcome of the organizational perspective consists in extending the scope of heredity beyond the genetic domain without merging it with the broad category (...) of cross-generation stability. After discussing some implications, we conclude with a reflection on the relationship between stability and variation. 1Introduction2From Extended Heredity to Cross-generation Stability 2.1Extending the scope of heredity: A brief state of the art2.2Rethinking heredity: Conceptual challenges3Biological Heredity in Light of Organization 3.1Biological organization within organisms and beyond3.2Extending organization in time3.3What is biological heredity?4Implications and Objections 4.1Heredity as a specific kind of cross-generation stability4.2Heredity at various levels of description4.3Non-functional and dysfunctional objects5Conclusions: From Conservation to Variation. (shrink)

The paper investigates the ethics of information transparency (henceforth transparency). It argues that transparency is not an ethical principle in itself but a pro-ethical condition for enabling or impairing other ethical practices or principles. A new definition of transparency is offered in order to take into account the dynamics of information production and the differences between data and information. It is then argued that the proposed definition provides a better understanding of what sort of information should be disclosed and what (...) sort of information should be used in order to implement and make effective the ethical practices and principles to which an organisation is committed. The concepts of “heterogeneous organisation” and “autonomous computational artefact” are further defined in order to clarify the ethical implications of the technology used in implementing information transparency. It is argued that explicit ethical designs, which describe how ethical principles are embedded into the practice of software design, would represent valuable information that could be disclosed by organisations in order to support their ethical standing. (shrink)

Teller argued that violations of Bell’s inequalities are to be explained by interpreting quantum entangled systems according to ‘relational holism’, that is, by postulating that they exhibit irreducible (‘inherent’) relations. Teller also suggested a possible application of this idea to quantum statistics. However, the basic proposal was not explained in detail nor has the additional idea about statistics been articulated in further work. In this article, I reconsider relational holism, amending it and spelling it out as appears necessary for a (...) proper assessment, and application, of the position. †To contact the author, please write to: FB Philosophie‐Zukunftskolleg, University of Konstanz, Universitätstraße 10, 78464, Konstanz, Germany; e‐mail: matteo.morganti@uni ‐konstanz.de. (shrink)

The present paper discusses different approaches to metaphysics and defends a specific, non-deflationary approach that nevertheless qualifies as scientifically-grounded and, consequently, as acceptable from the naturalistic viewpoint. By critically assessing some recent work on science and metaphysics, we argue that such a sophisticated form of naturalism, which preserves the autonomy of metaphysics as an a priori enterprise yet pays due attention to the indications coming from our best science, is not only workable but recommended.

This article provides a much-needed introduction to the philosophical debates around nihilism and negative thought which preoccupied many Italian left intellectuals in the seventies, and which still have important repercussions today. In order to present the principal stakes of the ‘Left Heideggerian’ current, the article undertakes a close reading of Massimo Cacciari’s 1976 book Krisis, and of Antonio Negri’s critical response to it—first in a review of the book, and then in a number of texts from the seventies and eighties, (...) closely analysed by Mandarini, in which Negri develops a positive political metaphysics. This contrast between Cacciari and Negri allows Mandarini to investigate the significance of seemingly recondite philosophical issues to the development of Italian radical political thought, and to identify some of the key stakes of this debate: the status of politics and the political, the role of ontology, the place of dialectics and, crucially, the opposition between Cacciari’s formalistic understanding of negativity and Negri’s link between negativity and antagonism. (shrink)

Since the discovery of the double helical structure of DNA, the standard account of the inheritance of features has been in terms of DNA-copying and DNA-transmission. This theory is just a version of the old theory according to which the inheritance of features is explained by the transfer at conception of some developmentally privileged material from parents to offspring. This paper does the following things: (1) it explains what the inheritance of features is; (2) it explains how the DNA-centric theory (...) emerged; (3) it clarifies the relation between the DNA-centric theory and the ‘unfolding’ theory of development; (4) it argues that (given what we now know about developmental processes and genetic activity) the DNA-centric theory should be abandoned in favour of a pluralistic (but not holistic) theory of the inheritance of features. According to this pluralistic theory, the reliable reoccurrence of phenotypes must be explained by appealing not only to processes responsible for the reliable reoccurrence of genetic developmental factors but also to processes responsible for the reliable reoccurrence (or persistence) of nongenetic developmental factors. (shrink)

Courtesy of its free energy formulation, the hierarchical predictive processing theory of the brain (PTB) is often claimed to be a grand unifying theory. To test this claim, we examine a central case: activity of mesocorticolimbic dopaminergic (DA) systems. After reviewing the three most prominent hypotheses of DA activity—the anhedonia, incentive salience, and reward prediction error hypotheses—we conclude that the evidence currently vindicates explanatory pluralism. This vindication implies that the grand unifying claims of advocates of PTB are unwarranted. More generally, (...) we suggest that the form of scientific progress in the cognitive sciences is unlikely to be a single overarching grand unifying theory. (shrink)

Letheby’s "Philosophy of Psychedelics" relies on Predictive Processing to try and find unifying explanations relevant to understanding how serotonergic psychedelics work in psychiatric therapy, what subjective experiences are associated with their use and whether such experiences are epistemically defective. But if Predictive Processing lacks genuinely explanatory unifying power, Letheby’s account of psychedelic therapy risks being unwarranted. In this commentary, I motivate this worry and sketch an alternative interpretation of psychedelic therapy within the Reinforcement Learning framework.

Julian Dodd [2018] persuasively argues that John Cage’s 4′33″ should be characterised as a silent piece, as opposed to a sonically replete piece, containing the environmental sounds that occur as it is performed; a piece of performance art, but not a piece of music; a work of conceptual art. While I agree with Dodd’s claims, I contend that he fails to account for two features of 4′33″. I argue that a qualified description of Cage’s work as belonging to a subgenre (...) of conceptual art could address these shortcomings. (shrink)

We analyze the notion of guessing model, a way to assign combinatorial properties to arbitrary regular cardinals. Guessing models can be used, in combination with inaccessibility, to characterize various large cardinal axioms, ranging from supercompactness to rank-to-rank embeddings. The majority of these large cardinal properties can be defined in terms of suitable elementary embeddings j:Vγ→Vλ. One key observation is that such embeddings are uniquely determined by the image structures j[Vγ]≺Vλ. These structures will be the prototypes guessing models. We shall show, (...) using guessing models M, how to prove for the ordinal κM=jM) many of the combinatorial properties that we can prove for the cardinal j) using the structure j[Vγ]≺Vj. κM will always be a regular cardinal, but consistently can be a successor and guessing models M with κM=ℵ2 exist assuming the proper forcing axiom. By means of these models we shall introduce a new structural property of models of PFA: the existence of a “Laver function” f:ℵ2→Hℵ2 sharing the same features of the usual Laver functions f:κ→Hκ provided by a supercompact cardinal κ. Further applications of our analysis will be proofs of the singular cardinal hypothesis and of the failure of the square principle assuming the existence of guessing models. In particular the failure of square shows that the existence of guessing models is a very strong assumption in terms of large cardinal strength. (shrink)

The idea of an unchanging human nature has always had a special place in Western philosophical thought. Far from being uncontested, this idea has received criticism from different traditions of thought, which have seen it even as an obstacle to the understanding of ourselves. Now it appears in the shape of a renewed naturalism and the opposing forces are the same as in the past. This volume shows some lines of the current debate about human nature: the revival of Herodotus (...) and Protagoras's humanistic relativism and tolerance; Darwinian ethics; the critical relationship between neo-Aristotelian and neo-Kantian moral theories and the results of empirical science; the assumption about the existence of a “moral mind” based on an innate moral grammar; the multicultural political debate which considers the idea of human nature as a product and a tool of Western hegemony; and, finally, the reflection on sex and gender in the theory of difference and on the idea of "living" nature in the contemporary biopolitics. (shrink)

Falando do ponto de vista da eternidade, Meister Eckhart era totalmente alheio ao milenarismo. No evento sempre renovado do nascimento do logos no fundo da alma, o tempo para o turíngio deixa de existir. A mística eckhartiana, ultrapassando a contraposição entre “místico” e “intelectual”, revela seus fundamentos filosófico-intelectualistas na afinidade com o pensamento neoplatônico e seu elo com os movimentos populares do Outono da Idade Média.

After the Second World War, Italy experienced an economic miracle accompanied by the emergence of a material culture highly dense with meaning. This article adopts a second-order approach, which focuses on two concepts that emphasize the component of invention contained within the innovation process.Garboindicates the peculiarly Italian way of solving a constrained optimization problem in the design of everyday objects. Meanwhile, the concept ofcenacolo– whose etymological roots indicate conviviality and good living – made possible the study of the peculiar social (...) networks of the Milanese cultural landscape during the 1960s, which enabled important cross-fertilizations between industry, culture and art. To demonstrate the connections between invention andgarboandcenacoli, the examples of Olivetti (key player in then-nascent personal computer technology) and Bialetti (producer of the Moka coffee machine) are used as case studies of innovative solutions to constrained problems. Following an outline of elements promoting the success of each, the article identifies historically determined mechanisms, which enable us to imagine and (potentially) establish the evolutionary conditions for new pathways of invention. (shrink)

The rise of Bayesianism in cognitive science promises to shape the debate between nativists and empiricists into more productive forms—or so have claimed several philosophers and cognitive scientists. The present paper explicates this claim, distinguishing different ways of understanding it. After clarifying what is at stake in the controversy between nativists and empiricists, and what is involved in current Bayesian cognitive science, the paper argues that Bayesianism offers not a vindication of either nativism or empiricism, but one way to talk (...) precisely and transparently about the kinds of mechanisms and representations underlying the acquisition of psychological traits without a commitment to an innate language of thought. (shrink)