Under the conditions of quarantine, distance learning turned out to be the only acceptable form of education, which corresponds to the current world norms of today's postmodern world space, because this type of organization of the educational process is included in the list of institutional forms along with full-time, part-time, network, and the like. Each institution of higher education, within the granted autonomy, has developed and implemented a system of measures for the technological and technical aspects of the implementation of (...) the educational process under quarantine conditions. Along with the variety of forms of production of distance education, there are common problems and challenges for higher education institutions: the workload of both teachers and students has significantly increased; revealed the need for intensive training in the use of distance forms in the educational process; work intensified and it turned out to be obvious that specialized distance learning centers were functioning on the basis of higher educational institutions; Students with special educational needs require significant attention, both in terms of socio-psychological support and support in distance learning. The recommendations of the world community on the course of the educational process in the conditions of quarantine are considered. Most international organizations have implemented the statements and issued a set of recommendations for education systems that countries can use in making policy decisions and implementing specific action plans. (shrink)

En Mendoza, hacia 1883, El Instructor Popular publica en la sección Noticias la creación de la “policía escolar”. El entramado periodístico permite anudar ciertos espacios y ciertas prácticas que oficiarían de parturientas para ese “vigilante secreto” que se configuraba como uno de los pilares del Sistema Educativo emergente. El inspector que alude a las figuras del vigilante y el policía, visibiliza las del político y dirigente, e ilusiona en el consejero y auditor, formador e informador, abre un espacio de engendramiento (...) tendiente a generar posibilidades materiales de inclusión de la diversidad en el sistema educativo desde una praxis gestada como “investigación educativa”. (shrink)

Features of threatening cues and the associated context influence the perceived imminence of threat and the defensive responses evoked. To provide additional knowledge about how the directionality of a threat (i.e. directed-towards or away from the viewer) might impact defensive responses in humans, participants were shown pictures of a man carrying a gun (threat) or nonlethal object (neutral) directed-away from or towards the participant. Cardiac and electrodermal responses were collected. Compared to neutral images, threatening images depicting a gun directed-towards the (...) participant induced sustained bradycardia and an increased electrodermal response, interpreted as immobility under attack. This defensive immobility reaction is evoked by high perceived threat and inescapable situations and indicates intense action preparation. Pictures of guns directed-away from the participant induced shorter bradycardia and no significant modulation of the electrodermal response compared to neutral pictures, which might be consistent with the perception of a less threatening situation. The results show that the directionality of threat stimuli is a key factor that prompts different patterns of defensive responses. (shrink)

Jurisdiction, Scale and Governance: Chronotopes of Law develops a post-metaphysical framework for analyzing the spatio-temporal workings of law and other forms of governance. In this regard, it does not seek merely to combine analyses of legal temporality carried out by anthropologists with analyses of law and space carried out by geographers and socio-legal scholars. Adding two metaphysical abstractions together does not produce anything but somewhat more complex, but equally metaphysical, abstractions. After Kant, 'time' and 'space' are simply categories of human (...) understanding, not metaphysical entities. And, in this book Mariana Valverde develops an anti-metaphysical theoretical approach to law that aims not to theorize the world in general, but rather to be useful to researchers who seek to shed light on the actual workings of law and other forms of governance. Written by one of the foremost theorists in the area, this theoretically innovative work constitutes a major contribution to contemporary studies in law and society. (shrink)

Resumo O propósito deste trabalho consiste em analisar criticamente uma recente proposta formulada por Needham no âmbito da Filosofia da Química. Este autor toma como essencialmente apropriado o modelo clássico de redução Nageliano. O objetivo fundamental deste trabalho consiste em avaliar certas implicações ontológicas desta tese neorreducionista. Em particular, a autora argumentará que a tese da redução interteórica formulada por Needham apresenta certas limitações, que advêm de uma atenção insuficiente a problemas ontológicos fundamentais. Sendo que estes emergem de uma análise (...) cuidada a algumas alegadas relações redutoras entre teorias. Palavras-chave : modelo nageliano, redução entre teorias, redução ontológica, reducionismo eliminativista, referenciaThe purpose of this paper is to analyse Needham’s recent proposal in the field of philosophy of chemistry. According to this proposal, Nagelian model of reduction is essentially appropriate. The primary aim of this paper is to evaluate certain ontological implications of this neo-reductionist thesis. Specifically, I will argue that Needham’s thesis of intertheoretic reduction has some limitations: the proposal does not pay attention to some fundamental ontological problems that emerge from a watchful analysis of some allegedly reductive relations between theories. Keywords: eliminative reductionism, Nagelian model, ontological reduction, reduction among theories, reference. (shrink)

The objective of this article is to show Augustine’s originality in ascribing a key role to will in the cognitive activity. For him, knowledge is influenced by both will and love, and cannot be grasped without will. Grounded primarily on De trinitate, the article focuses on three kinds of knowledge that shed light on his peculiar view on will: self-knowledge, knowledge of God, and the knowledge of bodies.L’objectif de cet article est de montrer que l’originalité d’Augustin est d’attribuer un rôle (...) clé à la volonté dans l’activité cognitive. Pour lui, la connaissance est influencée tant par la volonté que par l’amour et ne peut être appréhenéee sans volonté. Se basant principalement sur De trinitate, cet article se concentre sur trois genres de connaissance qui mettent en lumière sa conception particulière de la volonté : la connaissance de soi, la connaissance de Dieu et la connaissance des corps. (shrink)

Given the scarcity of educational materials (EM) to guide nutrition education strategies for phenilketonuric (PKU) patients, the goal of the present study was to develop and analyse the appearance and content validity of a EM directed to phenylketonuric children and their caregivers. The EM was evaluated by five professionals with expertise in the management of PKU. The material comprised 20 pages. All categories presented a satisfactory Index of Content Adequacy, meaning that the material was coherent, relevant and well structured. The (...) final Flesch Reading Ease Score index was 77. The ‘ABC of Phenyl’ Manual is appropriate and therefore suitable for use as an adjuvant in the management of phenylketonuria with pediatric patients. (shrink)

The aim of this essay is to analyze the notion of “loving, knowing ignorance,” a type of “arrogant perception” that produces ignorance about women of color and their work at the same time that it proclaims to have both knowledge about and loving perception toward them. The first part discusses Marilyn Frye's accounts of “arrogant” as well as of “loving” perception and presents an explanation of “loving, knowing ignorance.” The second part discusses the work of Audre Lorde, Elizabeth Spelman, and (...) María Lugones in their attempts to deal with the issue of arrogant perception within feminism, and examines how Lugones's notion of “‘world’-traveling” may help us deal with “loving, knowing ignorance.” Ultimately, the author suggests that we need to become aware of instances of “loving, knowing ignorance,” especially if we are to stay true to Third Wave feminism's commitment to diversity. (shrink)

Existential space is lived space, space permeated by our raced, gendered selves. It is representative of our very existence. The purpose of this essay is to explore the intersection between this lived space and art by analyzing the work of the Cuban‐born artist Ana Mendieta and showing how her Siluetas Series discloses a space of exile. The first section discusses existential spatiality as explained by the phenomenologists Heidegger and Watsuji and as represented in Mendieta's Siluetas. The second section analyzes the (...) space of exile as a space of in‐between‐ness and borders. Lastly, the third section discusses temporality as it relates to the space of exile. Through the analysis of Mendieta's Siluetas, and in light of phenomenological accounts of space and the works of Anzaldúa and Mignolo, Ana Mendieta herself is disclosed as well as the space characteristic of those who can no longer be said to have a “home.” My exploration through my art of the relationship between myself and nature has been a clear result of my having been torn from my homeland during my adolescence. The making of my Silueta in nature keeps (makes) the transition between my homeland and my new home. It is a way of reclaiming my roots and becoming one with nature. Although the culture in which I live is part of me, my roots and cultural identity are a result of my Cuban heritage.1 As quoted in Gloria Moure, Ana Mendieta (Barcelona: Ediciones Polígrafa, S.A., 1996), 108. Ana MendietaLiving in a state of psychic unrest, in a Borderland, is what makes poets write and artists create.2 Gloria Anzaldúa, Borderlands La Frontera, The New Mestiza (San Francisco: Aunt Lute Books, 1987), 73. Gloria Anzaldúa. (shrink)

Draws from Latina feminism, existential phenomenology, and race theory to explore the concept of selfhood. This original study intertwining Latina feminism, existential phenomenology, and race theory offers a new philosophical approach to understanding selfhood and identity. Focusing on writings by Gloría Anzaldúa, María Lugones, and Linda Martín Alcoff, Mariana Ortega articulates a phenomenology that introduces a conception of selfhood as both multiple and singular. Her Latina feminist phenomenological approach can account for identities belonging simultaneously to different worlds, including immigrants, (...) exiles, and inhabitants of borderlands. Ortega’s project forges new directions not only in Latina feminist thinking on such issues as borders, mestizaje, marginality, resistance, and identity politics, but also connects this analysis to the existential phenomenology of Martin Heidegger and to such concepts as being-in-the-world, authenticity, and intersubjectivity. The pairing of the personal and the political in Ortega’s work is illustrative of the primacy of lived experience in the development of theoretical understandings of who we are. In addition to bringing to light central metaphysical issues regarding the temporality and continuity of the self, Ortega models a practice of philosophy that draws from work in other disciplines and that recognizes the important contributions of Latina feminists and other theorists of color to philosophical pursuits. Mariana Ortega is Professor of Philosophy at John Carroll University and coeditor (with Linda Martín Alcoff) of Constructing the Nation: A Race and Nationalism Reader, also published by SUNY Press. (shrink)

Mariana Tatrchuk. Guaranteeing of Freedom of Conscience and Religions in European Union and Ukraine. In this article analysis legal protection of functioning of religious denominations in European Union and Ukraine in the context of compliance with international law and law of European Union.

El siguiente texto intenta abordar la relación existente entre los procesos de globalización-mundialización y ciertas concepciones de historia que le son solidarias. Para lo anterior apela a las reflexiones realizadas por Marc Abélès en Política de la supervivencia y Michael Hardt y Antonio Negri en Imperio. En ambos análisis se puede percibir la importancia que tiene la historia como soporte de los procesos globales que entremezclan lo político, lo económico y lo cultural, procesos que parecen avanzar, según el curso de (...) la historia, y que permiten además dar referencia de sentido a los sujetos en sus procesos identitarios y de individuación. The following text tries to approach the relation between the globalization-mondialisation process and certain conceptions of history witch are solidary with them. For the previous thing, it appeals to the reflections realized by Marc Abélès in Politics of the survival and Michael Hardt and Antonio Negri in Empire. In both analyses it is possible to perceive the importance that takes the history as a support of the global processes that intermingle the politics, the economy and culture, processes that seem to advance according to the course that history has, and they allow to give in addition reference of sense to the subjects in his processes of identity and of individuation. (shrink)

El objetivo de este artículo es estudiar el carácter enigmático de la escritura de Heráclito de Éfeso tomando en consideración la tradición de los enigmas en Grecia antigua. Compararé algunos de sus aforismos con los acertijos compuestos por Cleobulina de Lindos para mostrar que en uno y otro caso la función del enigma es similar: ocultar lo evidente haciendo uso de diversas estrategias lingüísticas con vistas a ampliar tanto el conocimiento sobre el mundo como el conocimiento de sí.

No presente trabalho tentaremos apresentar, em um primeiro momento, os aspectos gerais da leitura que Althusser fez da obra de Maquiavel, com o fito de compreender de que modo nosso autor entende o momento político da fundação do Estado. Em um segundo momento, objetivamos contrapor essa posição com outros dois modos de entender a instituição ou fundação do político, embora também a partir de Maquiavel, considerando as propostas de Hanna Arendt e de Maurice Merleau-Ponty. Por fim, esforçar-nos-emos por extrair algumas (...) conclusões a respeito da produtividade e dos limites que cada um desses modelos hermenêuticos oferecem-nos para pensar o fenômeno da instituição política. (shrink)

_Phénoménologie de la perception _es, sin duda, una de las obras más potentes del pensamiento francés del siglo XX. Allí se plantea una pregunta antigua y novedosa al mismo tiempo, en el cruce de la filosofía fenomenológico-existencial con diversas disciplinas que se ocupan del viviente humano: ¿quién es el sujeto de percepción? Merleau-Ponty responderá en esta obra ya clásica: el cuerpo vivido. Éste será, a su vez, caracterizado como un tipo particular de movimiento, que, en el camino de la fenomenología (...) existencial, adquiere la forma de un _movimiento intencional_, de una trascendencia y, finalmente, de un movimiento de temporalización que es, en términos husserlianos, la propia subjetividad. Tomando como punto de partida estos análisis, buscaremos desarrollar en este trabajo la tesis según la cual el cuerpo vivido debe comprenderse, en _Phénoménologie de la perception_, como un _movimiento subjetivo transpersonal_. Para desarrollar esta idea, partiré de un panorama general sobre el problema de la relación entre cuerpo, movimiento y vida frente al cual _Phénoménologie de la perception _se presenta como una continuidad y como una ruptura. En segundo lugar, presentaré los conceptos fundamentales que conducen a la concepción merleau-pontyana del cuerpo vivido como movimiento subjetivo para, en tercer lugar, centrar mi lectura en las posibilidades abiertas por este análisis de la experiencia corporal que denomino _transpersonal_. (shrink)

The present review on dyadic coping (DC) aims at providing a critical integration of both the conceptual and empirical DC literature and overcoming the limitations of past reviews by (a) describing, comparing, and integrating all the DC models, (b) presenting and integrating findings from studies based on DC models, and (c) suggesting directions for further research. The DC models identified and compared include: The congruence model (Revenson, 1994 ), the relationship-focused model (Coyne and Smith, 1991 ; O'Brien and DeLongis, 1996 (...) ), the communal coping model (Lyons et al., 1998 ), the systemic-transactional model (Bodenmann, 1995, 1997 ), the relational-cultural model (Kayser et al., 2007 ), and the developmental-contextual coping model (Berg and Upchurch, 2007 ). After discussing each DC model, we advance a conceptual integration of all models, which serves as the framework to organize the review of the empirical literature. This integration includes the following DC dimensions: (a) Stress Communication, (b) Positive DC by One Partner (supportive DC, empathic responding, delegated DC, active engagement), (c) Positive Conjoint DC (common, collaborative, communal, mutual responsiveness); (d) Negative DC by One Partner (protective buffering, overprotection, and hostility/ambivalence), and (e) Negative Conjoint DC (common negative DC, disengaged avoidance). Developmental, relational, and contextual variables are included as factors shaping DC. To be included in the empirical review, articles had to be published in or a peer-reviewed journal in English and/or German before 2017 and include an original empirical study guided by one of the DC models. The review included 139 studies and, with the exception of the congruence model whose findings were discussed separately, findings were presented for overall DC and each of the dimensions identified in the conceptual integration. Findings were grouped also according to whether the stressor related or not to a medical or mental health condition. Demographic and cultural factors affecting DC were discussed. Overall, the empirical review suggests that in Western couples, positive individual, and conjoint DC forms, taken together or separately, have individual and relational benefits for couples coping with stress in general and/or mental health or medical stressors. Research on DC can be expanded to include other populations and stressors and use improved designs. (shrink)

Abstract:Jessica Elkayam asks Mariana Ortega about the influence both Latina feminisms and Martin Heidegger have had on the development of Ortega's mestiza theory.

This article calls for an examination of the spectral operations of the perceptual architecture of colonization in conjunction with the enactment of a decolonial feminism as proposed by María Lugones. The first section discusses both the notion of ghostly subjectivity from Lugones's early work as well as the echoes of this notion in her recent work on the coloniality of gender that emphasizes the gender/race/sex nexus. Subsequently, through a photographic example, the article presents an analysis of the perceptual operations of (...) specter‐making in practices of colonization in light of Lugones's understanding of the “light” and “dark” sides of the coloniality of gender. This analysis highlights not only the intricate nexus between racialization and gender and sex norms both in the past and in the present context, but it also points to the necessity for of a decolonial feminism attuned to perceptual practices or a decolonial aesthesis. (shrink)

En el presente artículo intentaremos mostrar que en el Eutidemo Platón desarrolla una crítica contra la dialéctica de los filósofos megáricos que tiene por objetivo señalar los aspectos problemáticos de la teoría del lenguaje que fundamenta el procedimiento erístico. Específicamente, Platón muestra que la falta de un criterio de verdad los lleva a comprometerse con enunciados que socavan los fundamentos de la dialéctica. In this paper we shall try to show that in the Euthydemus Plato develops a critic of the (...) Megarian's dialectic, which aims to point out the problematical sides of language theory underpinning the eristic procedure. Specifically, Plato shows that the lack of a criterion of truth leads them to commit to statements that undermine the foundations of dialectic. (shrink)

Este trabajo pretende elucidar los rasgos generales de la metafísica de los megáricos en contra de las interpretaciones tradicionales que les atribuyen la defensa de un monismo numérico o una teoría de las Formas. Con base en los testimonios sobre Euclides y Estilpón de Mégara, intentaré mostrar que la metafísica megárica se caracteriza principalmente por el desarrollo de los conceptos de unidad e identidad de cada cosa consigo misma, lo que conlleva el rechazo de la diferencia y, en consecuencia, de (...) cualquier tipo de cambio. Esta perspectiva no excluye la existencia de múltiples entidades que, sin embargo, no son Formas. Por esta razón, los megáricos no desarrollan un monismo de tipo numérico, sino que su visión es coherente con un monismo de tipo predicativo que impugna la posibilidad de adjudicar atributos múltiples a una misma entidad. This paper purports to clarify the general features of Megarian metaphysics against two traditional interpretations which ascribe to this philosophical group either the defense of a numerical monism or a theory of Forms. Based on the testimonies of Euclid and Stilpo of Megara, I will aim to show that a main characteristic of Megarian metaphysics is the development of the concepts of unity and identity of each thing to itself, which involves a disavowal of difference as a possible property and, consequently, of any kind of change. I also intend to show that, although this standpoint does not exclude the existence of multiple entities, it implies that these entities are not Forms. Consequently, the Megarians do not develop a numerical monism but a predicational one, according to which the adscription of many predicates to the same entity is rejected. (shrink)

It matters that we learn to walk our brave decolonizing talks. … Coalitions that are productive are based on principled associations of mutual understanding and respect, not just declarations of solidarity that mean well but because of privileges of class, "race" or ethnicity, gender, and sexuality do not engage the work of transforming such subjectivity.Silences, when heard, become the negotiating spaces for the decolonizing subject.In this article I reflect about "decolonial woes"—not the misfortunes and distress that are associated with expressions (...) such as "woe is me" but a kind of affliction that is inherent in resistant academic practices that despite their being resistant, even radical and transformative, are... (shrink)

According to María Zambrano in order to unravel the enigmas of life, the heart must have selfcontrol and for that it must be sustained. What does this mean? In order to answer this the question must first be directed to the person who asks it: contemporary man. This person lives a series of mome..

Aunque las primeras lecturas y apropiaciones de textos de Michel Foucault en Argentina datan de fines de la década de 1950, nos interesa aquí detenernos en algunas de las formas de circulación, lectura, interpretación y apropiación de las elaboraciones foucaultianas bajo las condiciones impuestas por la última dictadura militar argentina. Esta propuesta tiene, entonces, como objetivo principal reconstruir históricamente y analizar algunas de esas apropiaciones que, entre fines de la década de 1970 y principios de los ’80, se manifestaron en (...) las Ciencias Sociales, en debates académicos y en producciones relacionadas con problemáticas locales, bajo la hipótesis de que es posible divisar la vitalidad de un espacio público subterráneo que subsistió aun en las peores condiciones de opresión. Tomar algunos de estos casos nos permitirá explorar usos estratégicos en el ámbito político-intelectual que ampliaban los márgenes de un espacio público sofocado. (shrink)

Phenomenology is a philosophical perspective first established at the beginning of the twentieth century andremains being developed. It was shaped during the first quarter of that century, diversified during the secondone, and took multiple roads since the 1950s. As a result, it is not possible to talk of ‘the one’ phenomenology, but instead it is necessary to speak of a phenomenological ‘project’. The article presents an approach to the issues, method, and possible applications of phenomenological philosophy. First, it addresses the (...) meaning of the generalphenomenological project and that of the project of three of its classical representatives: Edmund Husserl, Martin Heidegger and Maurice Merleau-Ponty. Secondly, it introduces some of the key concepts of these philosophers, highlighting the continuities and breaks. Finally, it suggests a concrete example of a possible application of the phenomenological approach and method through our contemporary experience of corporeal distance. (shrink)

Lacker (1981) and Lacker & Akin (1988) developed a mathematical model of follicular maturation and ovulation; this model of only four parameters accounts for a large number of results obtained over the past decade or more on the control of follicular growth and ovulation in mammals. It establishes a single law of maturation for each follicle which describes the interactions between growing follicles. The function put forward is sufficient to explain the constancy of the number of ovulations or large follicles (...) in a female as well as the variability of this number among strains or species and for either induced or spontaneous ovulators. According to the model, the number of ovulations or large follicles lies between two limits that are themselves simple functions of two parameters of the model. Moreover, Lacker's model exhibits interesting characteristics in agreement with results obtained by physiologists: in particular, it predicts that the number of ovulating or large follicles is independent of:1. the total number of maturing follicles, 2. the process of recruitment of newly maturing follicles towards the terminal maturation (Poisson or other), 3. the form of the LH or FSH secretion curves as functions of the systemic level of oestradiol. The model further predicts that 4. selection and dominance of follicles result from the feedback between the ovary and the hypophysis through the interactions between follicles; these interactions are expressed by the maturation function of the model. 5. recovery from atresia is possible for a follicle: from decreasing, the rate of secretion of oestradiol may increase. 6. the revised model suggests a renewal of follicles during the sexual cycle, as waves of follicular growth. Lacker's model is a model of strict dominance; it maintains a hierarchy of the follicles as soon as they start their final maturation to the ovulations as that is observed in bird or reptile ovary. Such a strict hierarchy is possible but it is probably not a general situation in all mammals. We therefore modified the maturing function of the follicle in order to make it compatible with the observations of physiologists: follicles always interact as in the initial model but they individually become old, the hierarchy of follicles can be modified with time and the largest follicles do not indefinitely grow as in the initial model. (shrink)

El presente artículo tiene por objeto analizar la figura de los demagogoí en Política de Aristóteles y cómo éstos se relacionan con la democracia. Un estudio de la descripción de dicho vínculo no puede soslayar el peso que tienen los nómoi y los psephísmata. Si bien nos enfocaremos en los libros IV y V, tendremos en cuenta la totalidad de la obra. Nuestra hipótesis es que es posible reconocer una connotación peyorativa en el campo léxico que se mantiene incluso en (...) los pasajes en donde la crítica ha visto un sentido neutro en dichas palabras. (shrink)

The aim of this essay is to carry out an analysis of the multi-voiced, multi-cultural self discussed by Latina feminists in light of a Heideggerian phenomenological account of persons or "Existential Analytic." In so doing, it points out similarities as well as differences between the Heideggerian description of the self and Latina feminists' phenomenological accounts of self, and critically assesses María Lugones's important notion of "world-traveling." In the end, the essay defends the view of a "multiplicitous" self which takes insights (...) from Lugones's view of the self that "travels 'worlds'" and from other Latina feminists' accounts of self as well as from Martin Heidegger's account of Dasein. (shrink)

As part of a book symposium on Erwin Dekker's Jan Tinbergen (1903–1994) and the Rise of Economic Expertise (2021), Mariana Mortágua and Francisco Louçã reflect on the context of Tinbergen’s evolution and, more specifically, his change(s) of focus on how to engineer social progress compared to that of the closest of his colleagues, Ragnar Frisch.

The article presents a study that aims to bring together the image and the word or ways of knowing through the concept of words and their respective ways to see images. Accordingly, when words are put together, phenomenological insight has been followed which does justice to lived experiences. Moreover, the author stresses the idea of the punctum in words as a wound.

Gender researchers have only recently begun to identify how women perceive and explain the costs and benefits associated with different femininities. Yet status hierarchies among historically white college sororities are explicit and cannot be ignored, forcing sorority women to grapple with constructions of feminine worth. Drawing on interviews with women in these sororities, we are able to capture college women’s attitudes toward status rankings that prioritize adherence to narrow models of gender complementarity. Sorority chapters were ranked according to women’s perceived (...) heterosexual appeal to elite men. Women believed that top-ranked sororities conferred social power whereas middle- and bottom-ranked sororities offered greater freedom from policing over members’ bodies, fashion, and socializing. However, middle- and bottom-ranked sororities sometimes sought to rise in the rankings. When this occurred, existing members were marginalized, and a new pledge class with a greater tolerance for socializing with high-status “rapey” fraternities was sought. Women’s discussions of sorority rankings show evidence of a hybrid femininity that fuses practices from traditional models of gender complementarity and more recent models of women’s empowerment. (shrink)

Enhancing research and development and ensuring equitable pricing and access to cutting-edge treatments are both vital to a biopharmaceutical innovation system that works in the public interest. However, despite delivering numerous therapeutic advances, the existing system suffers from major problems: a lack of directionality to meet key needs, inefficient collaboration, high prices that fail to reflect the public contribution, and an overly-financialized business model.