We define a complete theory SHF e of separably closed fields of finite invariant e (= degree of imperfection) which carry an infinite stack of Hasse-derivations. We show that SHF e has quantifier elimination and eliminates imaginaries.

This article addresses the sacredness of Ayahuasca from the perspective of the global shamanic vocation. If encounters with Ayahuasca are said to revitalize forms of sacredness in contemporary societies, this is perhaps clearest in cases where individuals understand themselves to be called to lead ceremonies. Recognizing the global scale of Ayahuasca shamanism, we compare facilitators of ceremonies in two societies to discern differences and similarities in how Ayahuasca vocations exist in differently modernized societies: Peru, a predominantly Catholic society with a (...) substantial Indigenous Amazonian population and an active Ayahuasca shamanism tourism sector, and Denmark, a secular society in Northern Europe, where Ayahuasca is illegal. Building on recent reappraisals of Weber’s reflection on vocation and Durkheim’s theory of the sacred, we argue that being called by Ayahuasca to follow shamanic vocations in contemporary societies leads to tensions around the need to both justify and resist the rationalization of Ayahuasca. (shrink)

Alm, Margit Review of: Countdown: Our last, best hope for a future on earth?, by Alan Weisman, First Published in the US by Little, Brown and Company, Hachette Book Group ISBN 978-1-4087-0267-3.

Alm, Margit Review of: Growing for broke: How the government has sold out to private interests, by Peter North, Published in 2016 by Tomorrow Press, PO Box 238, Berwick, Vic. 3806 ISBN 978-168418977-9.

As artificial intelligence systems are becoming increasingly autonomous and will soon be able to make decisions on their own about what to do, AI researchers have started to talk about the need to align AI with human values. The AI ‘value alignment problem’ faces two kinds of challenges—a technical and a normative one—which are interrelated. The technical challenge deals with the question of how to encode human values in artificial intelligence. The normative challenge is associated with two questions: “Which values (...) or whose values should artificial intelligence align with?” My concern is that AI developers underestimate the difficulty of answering the normative question. They hope that we can easily identify the purposes we really desire and that they can focus on the design of those objectives. But how are we to decide which objectives or values to induce in AI, given that there is a plurality of values and moral principles and that our everyday life is full of moral disagreements? In my paper I will show that although it is not realistic to reach an agreement on what we, humans, really want as people value different things and seek different ends, it may be possible to agree on what we do not want to happen, considering the possibility that intelligence, equal to our own, or even exceeding it, can be created. I will argue for pluralism which is compatible with objectivism. In spite of the fact that there is no uniquely best solution to every moral problem, it is still possible to identify which answers are wrong. And this is where we should begin the value alignment of AI. (shrink)

This article focuses on healthcare ethics discussions in Estonia. We begin with an overview of the reform policies that the healthcare institutions have undergone since the region regained independence from the Soviet Union in 1991. The principles of distributing healthcare services and questions regarding just what ethical healthcare should look like have received abundant coverage in the national media. An example of this is the exceptionally public case of V—a woman with leukemia whose expensive drugs the national health insurance fund (...) refused to compensate. In our subsequent discussion, we focus on a grand-scale local healthcare and research project—the Estonian Genome Project—that attempts to include 1 million DNA samples into one database. (shrink)

Photographs and text document disappearing cultural landscapes and lifestyles in rural China, capturing poignant scenes far from Beijing or Shanghai. Just a few kilometers from the glittering skylines of Shanghai and Beijing, we encounter a vast countryside, an often forgotten and seemingly limitless landscape stretching far beyond the outskirts of the cities. Following traces of old trade routes, once-flourishing marketplaces, abandoned country estates, decrepit model villages, and the sites of mystic rituals, the authors of this book spent seven years exploring, (...) photographing, and observing the vast interior of China, where the majority of Chinese people live in ways virtually unchanged for centuries. China's Vanishing Worlds is an impressive documentation in images and text of modernization's effect on traditional ways of life, and a sympathetic portrait of lives burdened by hardship but blessed by simplicity and tranquility. The scars of China's recent history and the decay of centuries-old traditions are made visible in this volume, but so is the lure and promise of technology and another life for young people. In the next twenty years, an estimated 280 million Chinese villagers will become city dwellers, leaving their ancestral homes in search of urban jobs and opportunities. In striking and evocative color photographs, we see picturesque villages set against a background of rolling hills, planned centuries ago according to the principles of feng shui; a restaurant with bright pink resin chairs and a wide-screen television; traditional buildings preserved by the accident of poverty and isolation; ramshackle rooms decorated with portraits of Chairman Mao; backpack-wearing children walking to school; festivals with elaborately costumed performers; old men playing cards; buyers and sellers at open-air markets. China's Vanishing Worlds offers readers a rare opportunity to glimpse China as it once was, and as it will soon no longer be. (shrink)

Physiologically accurate mouse models of cancer are critical in the pre‐clinical development of novel cancer therapies. However, current standardized animal‐housing temperatures elicit chronic cold‐associated stress in mice, which is further increased in the presence of tumor. This cold‐stress significantly impacts experimental outcomes. Data from our lab and others suggest standard housing fundamentally alters murine physiology, and this can produce altered immune baselines in tumor and other disease models. Researchers may thus underestimate the efficacy of therapies that are benefitted by immune (...) responses. A potential mediator, norepinephrine, also underlies stress pathways common in mice and humans. Therefore, research into mechanisms connecting cold‐stress and norepinephrine signaling with immune depression in mice could highlight new combination therapies for humans to simultaneously target stress while stimulating anti‐tumor immunity. (shrink)

THE STRUGGLE FOR THE WORKERS - POLITICAL CONCEPTUALIZATIONS OF 'THE WORKER', 1750-2015Although ‘the worker’ has been one of the key concepts in political language since the second half of the 19th century only few studies have been made of the historical shifts in its definition and semantic demarcation. Inspired by present day semantic shifts in the meaning and use of ‘the worker’ in Danish political debate, this article examines the long history of the politicization of the concept. With inspiration from (...) Reinhart Kosellecks Begrieffsgeschichte, the article analyzes how ‘the worker’ functions as both an indicator of and a factor in the creation of ‘the modern’. From being a concept used purely as a descriptive category for the wageworker in manual production in the pre-1790-era it changes into a category defining the workers as a social group with a revolutionary potential. The article argues that the concept plays a key role in political parties’ different strategies of mobilization and legitimization, and that since the 1970s a definitive change can be identified. A change that embodies what Francois Hartog has described as a transition from the future-oriented to the presentist regime. (shrink)

Apoptosis is a physiological mechanism for the removal of unwanted or damaged cells. Apoptotic cells are rarely seen in living tissues, however, because of their rapid and efficient removal by phagocytosis. Phagocytotic cells such as macrophages or dendritic cells recognize apoptotic cells by specific changes of cell surface markers, which usually are not present on normal cells. One such event is the exposure of phosphatidylserine, which moves from the plasma membrane inner leaflet to the outer leaflet in preapoptotic cells. An (...) unresolved problem, however, was the nature of the phosphatidylserine receptor on the phagocytotic cells. In a recent issue of Nature, Fadok et al.(1) have reported the cloning of a phosphatidylserine receptor using an antibody raised against activated macrophages. Antibody treatment of these macrophages blocks this capacity to engulf. BioEssays 22:878–881, 2000. © 2000 John Wiley & Sons, Inc. (shrink)

This reply focusses on three aspects: advantages and disadvantages of our proposed ‘cooperative entry certificates’ for the countries of origin, for the migrants, and for the host countries. It analyzes in what respects our proposal can be improved based on the valuable points made by the commentators. In addition, the question of how to deal with winners and losers within the three groups is discussed.

Name der Zeitschrift: Kant-Studien Jahrgang: 109 Heft: 4 Seiten: 597-634.

Auf die Frage nach der Rationalität des Glaubens hat William P. Alston, einer der prominentesten Vertreter der Analytischen Religionsphilosophie, eine zeitgemäße, aber auch spannungsreiche Antwort vorgelegt. Alstons Ansatz wird in diesem Buch systematisch aufgearbeitet und damit einer breiteren Rezeption im deutschsprachigen Raum zugänglich gemacht. Die Analyse der Autorin Margit Wasmaier macht deutlich, dass Alston angesichts der Frage, ob man religiöse Überzeugungen heute überhaupt noch begründet vertreten kann, einen pragmatischen Weg einschlägt, ohne aber den Standpunkt eines metaphysischen Realismus zu verlassen.

Large-scale migration is one of the most topical issues of our time. There are two main problems. First, millions of persons will enter Europe in the short and middle run in spite of the firewalls we have built. When the income levels in the development countries raises, the migration pressure will even become stronger for a long time. Second, the present integration policy in most European countries is deficient. In contrast to common knowledge, strong social benefits for migrants, multicultural policies (...) and fast naturalization do not further integration. To address these two problems we propose a procedure that takes into account that most migrants react to incentives in a rational way. Migrants in our countries are joining a cooperative and take advantage of many collective goods and social institutions the citizen of the immigration countries have provided. Migrants therefore should pay an entry fee to join the cooperative. This proposal has positive consequences for both the countries of immigration and of origin, as well as for actual and would-be immigrants. It has many advantages compared to other schemes. (shrink)

Performance evaluation in research is more and more based on numbers of publications, citations, and impact factors. In the wake of New Public Management output control has been introduced into research governance without taking into account the conditions necessary for this kind of control to work efficiently. It is argued that to evaluate research by output control is counterproductive. It induces to substitute the ‘taste for science’ by a ‘taste for publication’. Instead, input control by careful selection and socialization serves (...) as an alternative. (shrink)

Open source software production is a successful new innovation model which disproves that only private ownership of intellectual property rights fosters innovations. It is analyzed here under which conditions the open source model may be successful in general. We show that a complex interplay of situational, motivational, and institutional factors have to be taken into account to understand how to manage the ‘tragedy of the commons’ as well as the ‘tragedy of the anticommons’. It is argued that the success of (...) this new innovation model is greatly facilitated by a well balanced portfolio of intrinsic and extrinsic motivation, low costs for contributors and governance mechanisms that do not crowd out intrinsic motivation. (shrink)

Whereas in the 1970s early bioethicists believed that bioethics is an arena for the application of philosophical theories of utilitarianism, deontology, and natural law thinking, contemporary policy-oriented bioethicists seem rather to be keen on framing ethical issues through political ideologies. Bioethicists today are often labeled “liberal” or “communitarian,” referring to their different understandings of the relationship between the individual and society. Liberal individualism, with its conceptual base of autonomy, dignity, and privacy, enjoyed a long period of dominance in bioethics, but (...) it has increasingly come under attack from ideologies promoting a more salient role for concepts of solidarity, community, and public interest. (shrink)

_This article explores Vilhjálmur Árnason’s critique of contemporary bioethics, particularly its limited focus on individualistic principles, and its neglect of the broader social implications of emerging technologies. Vilhjálmur 1 argues that the commonly used “four principles approach”—respect for autonomy, beneficence, non-maleficence, and justice—is inadequate for addressing the complex ethical and societal impacts of new technologies. He suggests that ethical evaluations must extend beyond immediate individual risks to consider broader societal consequences._ _In critiquing overly individual-centered bioethical frameworks, Vilhjálmur raises a critical (...) theoretical question: what kind of ethical theory does bioethics truly require? This examination considers whether Vilhjálmur’s critique of the four-principles approach is justified and whether a more expansive ethical framework or theory of value is needed to specify and rank bioethical principles. By scrutinizing collective values like solidarity and the notion that “the personal is political” this paper suggests that new layers of disagreement arise, moving beyond traditional debates over moral theories. In a diverse society with conflicting values, such conflicts may be unavoidable. However, by highlighting the interconnection between individual moral agency and socio-political context, Vilhjálmur underscores the importance of self-reflection on personal values and the need to seek understanding across differing viewpoints in bioethical discussions_. _Keywords_: bioethics, personalized medicine, genetic database, four-principles approach, principlism, pluralism, value, ethical theory, personal is political, socio-political context. (shrink)

This article challenges hierarchical and binary thinking in constitutional theory, and offers an alternative basis that draws on multidimensionality. The recognition that constitutionalism is a collection of ingrained tensions between competing forces and conceptual bases is applied in a study of the executive branch, a field that is especially lacking in general theory. The existing research of the executive is almost entirely concerned with specific legal systems and is typically normative; descriptively, references to puzzles and ambiguity offer an inadequate, a-theoretical (...) basis for the understanding of the nature of the executive. Rejecting three alternative models, two of them hierarchical, the third, binary, I reach the internal tension model, which acknowledges the internal irresolvable tension between the executive’s subservience to law and its dominance beyond law, which underlies executive action. The article addresses the ways law can, and does, maintain this internal tension, and ends with some comments on future research directions. (shrink)

Muscle synergies reflect the presence of a common neural input to multiple muscles. Steering small sets of synergies is commonly believed to simplify the control of complex motor tasks like walking and running. When these locomotor patterns emerge, it is likely that synergies emerge as well. We hence hypothesized that in children learning to run the number of accompanying synergies increases and that some of the synergies’ activities display a temporal shift related to a reduced stance phase as observed in (...) adults. We investigated the development of locomotion in 23 children aged 2–9 years of age and compared them with seven young adults. Muscle activity of 15 bilateral leg, trunk, and arm muscles, ground reaction forces, and kinematics were recorded during comfortable treadmill walking and running, followed by a muscle synergy analysis. We found that toddlers and preschoolers utilize a “walk-run strategy” when learning to run: they managed the fastest speeds on the treadmill by combining double support and flight phases. In particular the activity duration of the medial gastrocnemius muscle was weakly correlated with age. The number of synergies across groups and conditions needed to cover sufficient data variation ranged between four and eight. The number of synergies tended to be smaller in toddlers than it did in preschoolers and school-age children but the adults had the lowest number for both conditions. Against our expectations, the age groups did not differ significantly in the timing or duration of synergies. We believe that the increase in the number of muscle synergies in older children relates to motor learning and exploration. The ability to run with a FP is clearly associated with an increase in the number of muscle synergies. (shrink)

If we ascribe someone an intention we presuppose that his actions are directed towards a goal. The origin of the word “intention” is derived from the Latin word “tendere” which means “to strain” or “tense” (a muscle) and together with the prefix “in” the word denotes someone’s “focusing on” or “being directed at an object”. If someone intends to do something one is directed towards an ob-jective. Whereas intention is a set of coordinated acts as part of an overall en-deavour (...) to achieve X, the objective is X itself. In English the expression intention is used for a determination to act in a certain way. The related expression ‘purpose’ denotes as well an intention or plan but additionally points to the reason for an action. German has the two expressions ‘Intention’ and ‘Absicht’. Both are synonymous but with ‘Absicht’ it is usually assumed that measures have been taken to achieve an envisaged objective. As such it was particularly used in Austrian officialese of the state administration in the late 19th and at the beginning of the 20th century. Whereas “intention” points to a person’s orientation or tendency towards an aim, “Ab-sicht” implies an elaborated plan ready to be put in practice. The word “Zweck” corresponds to purpose in English and refers to aspects, such as the function, benefit or application of an objective. (shrink)

The aim of this volume is to investigate three fundamental issues of the new millennium: language, truth and democracy. The authors approach the themes from different philosophical perspectives. One group of authors examines the use of language and the meaning of concepts from an analytic point of view, the ontology of scientific terms and explores the nature of knowledge in general. Another group examines truth and types of relation. A third group of authors focuses on the current factors influencing our (...) concept of democracy and its legal foundations and makes reference to moral aspects and the question of political responsibility. The chapters provide the reader with an overview of current philosophical problems and the answers to these questions will be decisive for future development. (shrink)

This descriptive qualitative study examined how the Storypath (also known as Storyline) approach to teaching social studies involves elementary school students in action civics (authentic civic activities, self-chosen issues, ongoing reflection, decisions valued). Storypath, a project-based approach, utilizes the story structure to frame learning through an inquiry process whereby students consider an overarching question about a topic, create a relevant setting, become characters in the setting, and engage in the plot of the story (critical incidents). This Storypath engaged a class (...) of ethnically and culturally diverse fifth graders in creating a music company (setting) dedicated to producing songs for social change. As company employees (characters), students researched issues they chose (affirming their agency in the learning process), then created songs and music videos for social impact. The arts (songs and videos) and technology (digital media) became integral to students’ efforts as they created and recorded music to share with the world. Students responded to Padlet and worksheet prompts, wrote song lyrics, and recorded music videos which all were analyzed to address this research question: What did authentic civic advocacy through creating music within the Storypath approach reveal about elementary students’ civic disciplinary knowledge, thinking, and skills? Findings revealed two overarching types of thinking: civic and political. Evidence indicates that civic thinking was justice-oriented for social well-being while political thinking was influence-oriented for strategic impact. This suggests that the Storypath implemented in this study can engage elementary school students in authentic civic advocacy within the classroom to cultivate civic and political thinking for meaningful participation in democratic life beyond the classroom. (shrink)

This article examines non-statutory executive powers, which are commonly employed in the modern state but rarely studied as a distinct concept. The article assesses three treatments of these powers available in current English public law—prerogative, common law powers which rely on analogies between the state and legal persons, and judicial review—and argues that they fail to provide a proper balance between legality and need. Royal prerogative connotes a shrinking reservoir of ancient powers, while non-statutory powers respond to unexpected futures and (...) statute’s intrinsic eventual failings. Analogies to legal persons fail to address the particularities of executive powers. Judicial review provides only a partial solution, since absence of parliamentary approval is not, in itself, ground for special treatment of executive action. The author joins calls for theoretization of public law and advances a model of executive powers that draws on a composite theory of the executive branch and its functions.This article examines non-statutory executive powers, which are commonly employed in the modern state but rarely studied as a distinct concept. The article assesses three treatments of these powers available in current English public law—prerogative, common law powers which rely on analogies between the state and legal persons, and judicial review—and argues that they fail to provide a proper balance between legality and need. Royal prerogative connotes a shrinking reservoir of ancient powers, while non-statutory powers respond to unexpected futures and statute’s intrinsic eventual failings. Analogies to legal persons fail to address the particularities of executive powers. Judicial review provides only a partial solution, since absence of parliamentary approval is not, in itself, ground for special treatment of executive action. The author joins calls for theoretization of public law and advances a model of executive powers that draws on a composite theory of the executive branch and its functions. (shrink)

It has sometimes been argued that Ludwig Wittgenstein’s philosophy is marked by relativism. According to this view people view general concepts in relative terms due to different considerations and perceptions. More specifically, there is a tendency among some philosophers to assign the Wittgensteinian concept of form of life to the idea of culture. The argument goes like this: as language games and forms of life develop within a particular culture and cultures are different they are no absolute phenomena but rather (...) relative depending on the frame within which they developed. I would like to take up this thought and examine whether we can find any relativistic position in Wittgenstein’s writings. The question is whether the existence of a multitude of forms of life points to any sort of relativism. Many philosophers have speculated over the significant concept of “form of life”. There has been an ongoing debate over the question whether the concept is to be understood in the singular or in the plural. The discussion here revolves around the question of whether there is only one prevailing form of life to which others can be subsumed. Or else, is there a variety of coexisting forms of life of equal value? (shrink)