Human hybridomas secreting monoclonal antibodies (MoAb) reactive with tumor cell antigens were produced in our laboratory by the immortalization of UC 729‐6 with B lymphocytes isolated from regional draining lymph nodes of cancer patients. MoAbs were purified from the hybridoma supernates by standard biochemical procedures for in vivo studies and by affinity methods for in vitro experiments. Using a novel method in the preparation of slides containing adherent tumor cells, immunoreactivities of the MoAbs were evaluated by an indirect immunofluorescence assay. (...) Based on this data, human MoAbs can, therefore, be used as research reagents. (shrink)

Features include a comprehensive review of existing material, combined with new perspectives to equip students for the challenges in the work environment; chapter overviews and student learning objectives offer a solid and useful framework in which to organise study; diagrams and charts present overviews and contexts for the subject to act as useful revision aids; effective pedagogy including a review of the arguments considered, a menu of seminar topics, and questions in every chapter, serving as an ideal basis for seminar (...) study; and additional open-ended simulations to allow students to work through unfolding scenarios. (shrink)

Originally published in 1988, M.C. Dillon's classic study of Merleau-Ponty is now available in a revised second edition containing a new preface and a new chapter on "Truth in Art." Dillon's thesis is that Merleau-Ponty has developed the first genuine alternative to ontological dualism seen in Western philosophy. From his early work on the philosophical significance of the human body to his later ontology of flesh, Merleau-Ponty shows that the perennial problems growing out of dualistic conceptions of mind and body, (...) subject and object, immanence and transcendence can be resolved within the framework of a new way of thinking based on the exemplar of the worldly embodiment of thought. (shrink)

This book will be a comprehensive exploration of the dynamic intersection between academic practice and research methodologies within higher education settings.

We give an example of a countable theory $T$ such that for every cardinal $\lambda \geq \aleph_2$ there is a fully indiscernible set $A$ of power $\lambda$ such that the principal types are dense over $A$, yet there is no atomic model of $T$ over $A$. In particular, $T$ is a theory of size $\lambda$ where the principal types are dense, yet $T$ has no atomic model.

Upshot: Responding to and further developing the points raised by the open peer commentaries, I discuss a range of themes, including possible roles of lecture-based teaching in a radical constructivist approach to education, approaches to the teaching of large cohorts in a radical constructivist manner, the role of assessment in students’ learning experiences, the distinction of “models of” student learning, contrasted with “models for” student learning, the distinction of literal conversation from an atmosphere conducive to conversation, and the use of (...) design-based tasks to support and encourage students’ individual conceptual constructing. (shrink)

Open peer commentary on the article “Design Research as a Variety of Second-Order Cybernetic Practice” by Ben Sweeting. Upshot: Based on Sweeting’s central question of what design can bring to cybernetics, this commentary extends and adds further depth to the target article. Aspects discussed include the nature of practice in relation to design, the introduction of designerly ways of acting and thinking through acting to cybernetics, and the re-introduction of material experimentation typical of early cybernetics.

This volume sheds light on still unexplored issues and raises new questions in the main areas addressed by the philosophy of science. Bringing together selected papers from three main events, the book presents the most advanced scientific results in the field and suggests innovative lines for further investigation. It explores how discussions on several notions of the philosophy of science can help different scientific disciplines in learning from each other. Finally, it focuses on the relationship between Cambridge and Vienna in (...) twentieth century philosophy of science. The areas examined in the book are: formal methods, the philosophy of the natural and life sciences, the cultural and social sciences, the physical sciences, and the history of the philosophy of science. (shrink)