ObjectiveThe effects and possible mechanisms of cerebellar high-frequency repetitive transcranial magnetic stimulation on swallowing-related neural networks were studied using resting-state functional magnetic resonance imaging.MethodA total of 23 healthy volunteers were recruited, and 19 healthy volunteers were finally included for the statistical analysis. Before stimulation, the cerebellar hemisphere dominant for swallowing was determined by the single-pulse TMS. The cerebellar representation of the suprahyoid muscles of this hemisphere was selected as the target for stimulation with 10 Hz rTMS, 100% resting motor threshold, (...) and 250 pulses, with every 1 s of stimulation followed by an interval of 9 s. The motor evoked potential amplitude of the suprahyoid muscles in the bilateral cerebral cortex was measured before and after stimulation to evaluate the cortical excitability. Forty-eight hours after elution, rTMS was reapplied on the dominant cerebellar representation of the suprahyoid muscles with the same stimulation parameters. Rs-fMRI was performed before and after stimulation to observe the changes in amplitude of low-frequency fluctuation and regional homology at 0.01–0.08 Hz, 0.01–0.027 Hz, and 0.027–0.073 Hz.ResultsAfter cerebellar high-frequency rTMS, MEP recorded from swallowing-related bilateral cerebral cortex was increased. The results of rs-fMRI showed that at 0.01–0.08 Hz, ALFF was increased at the pons, right cerebellum, and medulla and decreased at the left temporal lobe, and ReHo was decreased at the left insular lobe, right temporal lobe, and corpus callosum. At 0.01–0.027 Hz, ALFF was decreased at the left temporal lobe, and ReHo was decreased at the right temporal lobe, left putamen, and left supplementary motor area.ConclusionRepetitive transcranial magnetic stimulation of the swallowing cortex in the dominant cerebellar hemisphere increased the bilateral cerebral swallowing cortex excitability and enhanced pontine, bulbar, and cerebellar spontaneous neural activity, suggesting that unilateral high-frequency stimulation of the cerebellum can excite both brainstem and cortical swallowing centers. These findings all provide favorable support for the application of cerebellar rTMS in the clinical practice. (shrink)

Smartphone addiction behaviors are becoming more and more common with the rapid popularity and widespread use of smartphones. Such behaviors are significantly influenced by the overuse of smartphones before bedtime. In this study, the overuse of smartphones after 9:00 pm before bedtime was investigated by an online questionnaire. The sample consists of 1,035 college students in China. The artificial neural networks were applied to predict the use time of smartphones before bedtime based on their different usages, and the relationship between (...) smartphone usage and additive behaviors was analyzed. The results show that the neural network model can more accurately predict the usage time of smartphones according to the usage of smartphones before going to bed. At the same time, it is also found that the prediction accuracy of the samples that use the smartphone for less than half an hour and more than 3 h before bed is higher than that of other samples. Moreover, watching short videos and playing games are more likely to lead to mobile phone addiction behavior. These findings would help guide college students to correctly use phones and reduce smartphone addition, which is of great significance for mental health education. (shrink)

On the premise that the good knowing is the originary reality, this article provides a synopsis of Wang Yangming’s exposition of the fundamental essence of liangzhi. The self-existent resemblances of the originary reality are outlined and summarized as the eight virtues of liangzhi: voidness, intelligence, luminousness, awareness, constancy, happiness, true I, and purity. These eight virtues are, however, ultimately subsumed by the middle, which governs them in common. The middle is the original state and true form of the fundamental essence (...) of liangzhi, which Wang Yangming describes as a transparent mirror and level balance. (shrink)

From the 11th through 13th centuries, the mass of yogic techniques informed by the Yoganiruttara cycle of Buddhist Tantra flowed over the Himalayan range and extended to the Hexi Corridor. The Tibetan, Tangut, and Chinese peoples who had been exposed to such a yogic and tantric culture actively drew on Indian Buddhist legacies as taxonomical and conceptual device to structure and make sense of these cutting-edge contemplative techniques. One such discursive device was the Mahāmudrā rubric considered as the pinnacle of (...) a systematic presentation of both tantric and sūtric paths to ultimacy. In this article, I explore the sūtric path structure embedded within a 12th-century Tangut Mahāmudrā presentation—in the Keypoints of Mahāmudrā as the Ultimate along with its commentary—formulated under the Tibetan auspices. I analyze the relevance of the Keypoints exoteric expositions of Mahāmudrā to the Mahāyāna intellectual history through the lens of non-conceptual meditation scheme. In specific, I argue that the Tangut Mahāmudrā works under survey map out a “positive-mystical” paradigm of Buddhist soteriology shared across those Mahāyāna scholastic traditions inspired by the Buddha-nature doctrine to account for the tantric phenomenology. (shrink)

This paper focuses on the debate between Jonathan Dancy and Brad Hooker regarding the validity of moral particularism and investigates whether both philosophers have overlooked any important factors in their discussions. According to Jonathan Dancy’s ideas of particularism, morality which encompasses our moral thought, judgment, and the possibility of moral distinctions, is independent of the codification of moral principles. He appeals to holism in the theory of reasons to defend his belief that the same property or feature that is a (...) reason in one case can count morally for or against action in different circumstances. Hooker, on the other hand, takes issue with Dancy’s account by suggesting that moral particularism is socially impractical, and Dancy’s provision of premises ought to be overwhelmingly plausible. Hooker argues that moral particularism fails to provide the moral assurance that is required of a shared commitment to morality that brings about mutually beneficial practices that we can generalize in consideration of the features of contexts in which they take place within the specification of reason(s) for belief and action. By comparing Hooker’s example involving theoretical particularist Patty and the Rossian generalist Gerry with Dancy’s rebuttal, this paper propounds that Dancy and Hooker both insufficiently address the conceptual relation between moral obligation and accountability within the moral domain. Morality as accountability does not exclusively relate to the valuable consequences of creating and following rules and principles. Rather, it entails our obligations conceptually to hold ourselves mutually accountable if and only if there are existing general rules and principles that are also accessible to all members within the community bounded by such common moral knowledge. (shrink)

Abstract: When the Ming dynasty Confucian Wang Yangming (1472-1529) proposed his tenet of the unity of knowing and acting (zhi xing heyi 知行合一), he did so because he believed that Zhu Xi (1130-1200), his revered Song dynasty predecessor and architect of the School of Principle (Neo-Confucianism), had wrongly conceptually divided knowledge and action, and that this had led to profound problems of an existential nature for the individual with real-world consequences. For Wang Yangming, the relation between knowledge and action is (...) fundamentally one of identity, an identity grounded in the inherent, true condition of the vital being of the individual, in a unity of mind and body. He called this identity the original condition and original form of knowing and acting, explaining it in various ways. This article first explains how Wang Yangming positioned his tenet in relation to Zhu Xi’s conceptualization of the relation between knowledge and action, and then elucidates his conception of the unity of knowing and acting in four orientations, according to the different senses in which knowledge/knowing are understood: as perception, as awareness, as what is known, and as the innate knowing. (This is an abbreviated and edited translation of 論 ‘知行合一“的四重向度， 原载于《社会科学战线》2019年第2期). (shrink)

Not for the academic value of some of the situational events, often with a comprehensive, decisive, Yan'an new philosophy will the home of its columns. Will establish a new philosophy, a lot of grand strategy is one of the actions in Yan'an. This paper examines a new philosophy will be the basic process, an analysis of its membership and the subsequent effects, assessing its characteristics in the formation of contemporary Chinese culture, the unique role, made ​​a number of issues need (...) to be further explored. This paper shows that the new philosophy will not academics, but the educational organization. It is the ideology of expert training, knowledge and control of legal rights, the implementation of the regulatory action of self-sufficiency and closed culture strategy. New philosophy will be mainly in the construction and maintenance of highly exclusive mode of thinking to make contributions, as the full value of its effect remains to be thorough and reasonable debate. Some situational events, which have been neglected by academics, may be of significant importance. The Yan'an New Philosophy Association is an example. Its establishment was one of the ambitious strategic actions of the CCP in Yan'an. This paper examines the process of the YNPA's establishment, analyses the composition of its membership, assesses its unique effect on the formation of contemporary Chinese ideology, and raises some issues that are in need of further research. This study shows that the YNPA was an educational institution instead of an academic society, and that the experts in ideology it produced had exclusive power in the cultural domain and implemented the party's cultural policies. We can see that the YNPA greatly contributed to the construction and maintenance of a high degree of cultural exclusivity. A full picture of this association, however, requires much more in-depth studies. (shrink)

Faced with the choice between saving one person and saving two others, what should we do? It seems intuitively plausible that we ought to save the two, and many forms of consequentialists offer a straightforward rationale for the intuition by appealing to interpersonal aggregation. But still many other philosophers attempt to provide a justification for the duty to save the greater number without combining utilities or claims of separate individuals. I argue against one such attempt proposed by Iwao Hirose. Despite (...) being consequentialist, his argument is aggregation-free since it relies on a non-aggregative value judgement method, instead of interpersonal aggregation, to establish that (other things being equal) a state of affairs is better when more people survive therein. I do not take issue with its consequentialist element; rather, I claim that there is no good reason to adopt the method in question, and thus no good reason to be moved by his argument overall. What we are in search of is not merely a logically possible method that can produce the conclusion that we already want, but one that we have good reason to adopt. Hirose's argument elegantly demonstrates how it could possibly be true that it is right to save the greater number; but it fails to show that we have reason to believe so - even when we do not combine the interests of different individuals. (shrink)

Supply networks as complex systems are significant challenges for decision-makers in predicting the evolution of cooperation among firms. The impact of environmental heterogeneity on firms is critical. Environment-based preference selection plays a pivotal role in clarifying the existence and maintenance of cooperation in supply networks. This paper explores the implication of the heterogeneity of environment and environment-based preference on the evolution of cooperation in supply networks. Cellular automata are considered to examine the synchronized evolution of cooperation and defection across supply (...) networks. The Prisoner’s Dilemma Game and Snowdrift Game reward schemes have been formed, and the heterogeneous environment and environmental preference have been applied. The results show that the heterogeneous environment’s degree leads to higher cooperation for both Prisoner’s Dilemma Game and Snowdrift Game. We also probe into the impact of the environmental preference on the evolution of cooperation, and the results of which confirm the usefulness of preference of environment. This work offers a valuable perspective to improve the level of cooperation among firms and understand the evolution of cooperation in supply networks. (shrink)

Business Ethics, the Environment & Responsibility, EarlyView.

BackgroundTo investigate the factors related to approval after review by an Institutional Review Board, the structure equation model was used to analyze the latent variables ‘investigators’, ‘vulnerability’ and ‘review process’ for 221 proposals submitted to our IRB.MethodsThe vulnerability factor included vulnerable cases, and studies that involved drug tests and genetic analyses. The principal investigator factor included the license level of the PI and whether they belonged to our institution. The review factor included administration time, total review time, and revision frequency. (...) The revision frequency and total review time influenced the efficiency of review.ResultsThe latent variable of reviewing was the most important factor mediating the PIs and vulnerability to IRB review approval. The local PIs moderated with genetic study and revision frequency had an impact on the review process and mediated non-approval.ConclusionsBetter guidance of the investigators and reviewers might improve the efficiency with which IRBs function. (shrink)

Biological pacemakers can be achieved by various gene‐based and cell‐based approaches. Embryonic stem cells (ESCs)‐derived pacemaker cells might be the most promising way to form biological pacemakers, but there are challenges as to how to control the differentiation of ESCs and to overcome the neoplasia, proarrhythmia, or immunogenicity resulting from the use of ESCs. As a potential approach to solve these difficult problems, tissue‐engineering techniques may provide a precise control on the different cell components of multicellular aggregates and the forming (...) of a construct with‐defined architectures and functional properties. The combined interactions between ESC‐derived pacemaker cells, supporting cells, and matrices may completely reproduce pacemaker properties and result in a steady functional unit to induce rhythmic electrical and contractile activities. As ESCs have a high capability for self‐renewal, proliferation, and potential differentiation, we hypothesize that ESCs can be used as a source of pacemaker cells for tissue‐engineering applications and the ambitious goal of biological cardiac pacemakers may ultimately be achieved with ESCs via tissue‐engineering technology. -/- . (shrink)

People often judge trustworthiness based on others’ faces (e.g., facial expression and facial gender). However, it is unclear whether social context plays a moderating role in forming trustworthiness judgments. Based on the emotions as social information (EASI) model, differing contexts may impact the effect of facial expression; however, there is no evidence demonstrating that differing contexts will or will not influence the effect of facial gender. In this study, we used two experiments to examine how facial expression and facial gender (...) affect facial trustworthiness judgments and whether the effects on facial trustworthiness judgments are consistent in cooperative and competitive settings. Twenty-seven undergraduates (14 female; Mage = 21.81 years, SD = 2.66) participated in experiment 1. The results showed significant main effects of facial expression and facial gender as well as the interaction between them. To examine the social context effect, 28 undergraduates (18 female; Mage = 20.93 years, SD = 2.94) participated in experiment 2. The results showed the main effects of facial expression, facial gender, and social context. Moreover, there was a significant interaction between facial gender and facial expression and a marginally significant interaction between social context and facial expression. These results suggest that in the process of judging facial trustworthiness, individuals’ judgments are affected by both facial expression and facial gender. Furthermore, the effect of facial gender on facial trustworthiness judgments presents cross-situational stability, and the role of facial expression is influenced by the settings. These findings support and expand the EASI model. (shrink)

In the philosophical purview of our intellectual endeavors, Emil Brunner’s sojourn through the theological corridors reveals a tapestry of rigorous mental exercises and paradigmatic shifts. Commencing his exploration harmonized with the liberal theological currents, Brunner found himself adrift, embroiled in the tumultuous seas of Karl Barth’s unequivocal “No!” to the paradigms of natural theology, etching an indelible ideological chasm. Traversing three profound metamorphic epochs—initiating within the precincts of consciousness theology, an echo chamber of Schleiermacher’s musings, segueing into the gravitational pull (...) of dialectical theological realms, and reaching zenith in his unparalleled emphasis on the “Truth as Encounter”—Brunner’s spiritual and intellectual topography is an odyssey of profound depths. This literary endeavor plumbs the profundities of Brunner’s philosophical-theological metamorphosis. A journey delineating his intricate dance with Bergson’s intuitive paradigm, his symbolic lexicon of faith, an eventual critique of dialectical theology’s embrace, culminates in an intricate interpretation of sin and the imago Dei. Of paramount significance is Brunner’s theological bifurcation from Barth on the quintessential essence of human-divine dynamics. While both theological maestros recognize sin’s pervasive imprint on the human soul, Brunner postulates the tantalizing possibility of personal divine rendezvous. In this erudite exposition on Brunner’s theology, we embark on an intellectual odyssey, elucidating the subtle shades and profound resonances of his cognitive evolution. An evolution, wherein, juxtaposed against theological titans, he architects an idiosyncratic theological timbre echoing through the annals of time. (shrink)

Justin D’Arms and Daniel Jacobson have argued that to evaluate the funniness of a joke based on the consideration of whether it is morally appropriate to feel amused commits the “moralistic fallacy.” We offer a new and empirically informed reply. We argue that there is a way to take morality into consideration without committing this fallacy, that is, it is legitimate to say that for some people, witty but immoral jokes can fail to be funny because they are immoral. In (...) our account, one has an intramural moral reason not to feel amused if one focuses on the moral feature itself of a joke rather than the moral consequence implied in one’s reaction to the joke. When one judges a joke as not funny because of the intramural moral reason, one is in a negative emotional state with high arousal, for example, moral disgust or anger. This state is psychologically incompatible with amusement. That one has an intramural reason not to feel amused thus implies that one does not have a reason to feel amused. Moral consideration thus plays an indirect and appropriate role in the evaluation of the funniness of a joke. (shrink)

v.1. Yuhak ŭi parwŏn kwa wansŏng -- v. 2. Chungguk Yuhak ŭi chŏn'gae -- v. 3. Han'guk ŭi Yuhak (sang) -- v. 4. Han'guk ŭi Yuhak (ha) -- v. 5. Ilbon kwa Pet'ŭnam ŭi Yuhak.

While investigating the value of achievements, Dunkle claims that lucky achievements are possible. For instance, if a person does great works, then it is possible that the works have the status of achievements, even if luck plays a crucial role in doing the great works. Rather than examining Dunkle’s claim, this paper proceeds discussion under the assumption that lucky achievements are possible. In particular, based on this assumption, this paper suggests a new approach to the nature of achievement named the (...) Comparative Value Approach. According to the comparative value approach, a product can have the status of an achievement if the product is valuable in an achievement-relevant domain, and in that domain the product is valuable more than most other items which either have been achieved or can be achieved by others. This paper shows that the comparative value approach successfully explains the cases of achievements, including the cases of lucky achievements. Besides this reason, this paper provides three more reasons to show that the comparative value approach is a feasible view of achievements. The comparative value approach can accommodate the fact that there are various kinds of achievements; the approach can explain the relation between the nature of achievement and the achievement-value of a product; and the approach can show why in determining the status of a product it matters that for average people achieving a similar kind of product is sufficiently difficult. Based on these four reasons, this paper concludes that the comparative value approach is a plausible understanding of achievements. (shrink)

Some goals have special significance to agents. For instance, an agent could find her life worth living because she is pursuing her current goal, and the agent could also think that her previous life has no value because she did not pursue the current goal. If an agent’s current goal has special importance to the agent, then in terms of prudence the agent’s decision to obtain her current goal could be permissible even in the case where achieving her previous goal (...) brings out larger advantages. A widely endorsed thesis of prudence (i.e. the temporal neutrality thesis) does not successfully explain this phenomenon of goal achievement. Furthermore, the present-aim thesis and the harmony thesis also fail in explaining why an agent has prudential reason to prioritize her current goal. This paper introduces a new thesis of prudence, according to which an agent’s caring is significant in deciding whether the agent’s actions are prudentially permissible. In particular, after introducing this thesis named the care thesis, I argue that the care thesis can explain why an agent has reason to prioritize her current goal if the agent finds her life worth living due to her current goal. It is permissible that an agent obtains her current goal rather than previous goal because achieving her current goal benefits the agent’s cared one (i.e. the self who pursues her current goal). (shrink)

The redemption thesis assumes that how events in a person’s life are related to one another is important in evaluating the person’s welfare throughout life. In particular, according to this thesis of welfare, the fact that a person’s previous hardships contribute to bringing out the same person’s later successes, and the person would regard the hardships as having been worthwhile in light of the successes makes the person’s life better for the person herself. Recently, Ian D. Dunkle provided four objections (...) to the redemption thesis: the intuition concern, the different redemptions argument, the downplaying hardships argument, and the reconciled irreconcilables argument. This paper examines these four objections. In particular, this paper dismisses all the objections showing that the redemption thesis bases on an appealing idea, does not consider the degree of hardship significant in itself, has plausible reasons to evaluate hardships not as serious as people think, and can successfully reconcile its synchronic and diachronic evaluations. (shrink)

Due to the population ageing, building an elderly livable community has become an urgent task of social welfare development. This Public-Private Partnership construction project faces a variety of pressures from its complex stakeholders. Based on the Qingdao elderly livable community construction project, this paper builds up interpretations about its relationship governance by conducting stakeholder analysis. The paper aims to explore the relationship governance mechanism of multiple connections between related stakeholders. On the basis of complex network theory, this paper establishes a (...) stakeholder relationship network model and describes different modes of different stakeholder relationship in the Qingdao construction project. The paper analyzes the optimal decision-making behavior and interaction of different stakeholders, constructs the objective functions of stakeholder relationship network, applies centrality measure and dominant-set clustering to analyze the optimal conditions of the whole network, and finally carries out simulation calculation. The results show that it is feasible and effective to apply network analysis method to the study of stakeholder relationship in Public-Private Partnership construction projects. (shrink)

Abstract:Retro-writing has ethical implications. How a speaking subject applies a retro-perspective frames a piece of writing within certain cultural discourses. In contemporary Chinese poetry, cultural nostalgia and the attempted revival of ancient aesthetics is a complex issue, one that is largely the result of a general interest in cultural archeology, writers’ anxiety of influence, the desire to escape from various political pressures, and the claim of a need for a distinctive Chinese cultural identity. The subject in many contemporary Chinese poems, (...) in many cases, is a male subject striving to retrieve the premodern holistic state of being, which is illusory. Han Bo’s two poems “Modern Sex Machine” and “Mass(ive) Killing Machine” are unique in that they examine the bludgeoning of modernity within postmodern parameters and attempt to map the dynamics of modern and contemporary subjecthood, which is in fact a transcorporeal experience of the subject as that which is, ultimately, subjectless. Such work, in creating a cross-corporeal subjectless subject, embraces alterity and renders possibilities for the reader to reject a prior unitary transcendental subject that is illusory, and thereby to discover the beings of themselves and their roles in the world—and to extend this work of reconfiguring subjecthood from literature into other aspects of social life. (shrink)

Background: Truth-telling toward terminally ill patients is a challenging ethical issue in healthcare practice. However, there are no existing ethical guidelines or frameworks provided for Chinese nurses in relation to decision-making on truth-telling of terminal illness and the role of nurses thus is not explicit when encountering this issue. Objectives: The intention of this paper is to provide ethical guidelines or strategies with regards to decision-making on truth-telling of terminal illness for Chinese nurses. Methods: This paper initially present a case (...) scenario and then critically discuss the ethical issue in association with ethical principles and philosophical theories. Instead of focusing on attitudes toward truth disclosure, it aims to provide strategies regarding this issue for nurses. It highlights and discusses some of the relevant ethical assumptions around the perceived role of nurses in healthcare settings by focusing on nursing ethical virtues, nursing codes of ethics, and philosophical perspectives. And Confucian culture is discussed to explicate that deontology does not consider family-oriented care in China. Conclusion: Treating each family individually to explore the family’s beliefs and values on this issue is essential in healthcare practice and nurses should tailor their own approach to individual needs regarding truth-telling in different situations. Moreover, the Chinese Code of Ethics should be modified to be more specific and applicable. Finally, a narrative ethics approach should be applied and teamwork between nurses, physicians and families should be established to support cancer patients and to ensure their autonomy and hope. Ethical considerations: This paper was approved by the Ethics Committee of The Second Affiliated Hospital of Guangzhou Medical University. The authors have obtained consent to use the case study and it has been anonymised to preserve the patient's confidentiality. (shrink)

Article aims to explore Augustine's "two cities" theory. First, a brief discussion of the "City of God" writing background and the main structure; Secondly, in both religious and secular aspects of life on the analysis of the "City of God" on the "two cities" of the main points; again, three perspectives of the "two cities" theory of history and ideological background. Although the "two cities" doctrine embodies a form with two points tend to think, but both different from the ontological (...) dualism and the dualism of body and soul, but also avoids the complex social reality for too absolute two points. The focus of this study is Augustine's doctrine of the "Two Cities." The first part treats the background and the structure of the City of God. In the second and the third part, the essay examines both the religious and the temporal aspect of this doctrine. Finally, the historical and intellectual background of the doctrine is discussed. The author argues that even though the doctrine of the "Two Cities" manifests a dualistic tendency in the thought of Augustine, it can hardly be labeled as a dualism. (shrink)

This paper conducts a numerical simulation of the antiseismic performance for single-layer masonry structures, completes a study on crack distributions and detailed characteristics of masonry structures, and finally verifies the correctness of the numerical model by experimental tests. This paper also provides a reinforced proposal to improve the antiseismic performance of single-layer masonry structures. Results prove that the original model suffers more serious damage than the reinforced model; in particular, longitudinal cracks appear on bottoms of two longitudinal walls in the (...) original model, while these cracks appear later in the reinforced model; a lot of cracks appear on the door hole of the original model, and no crack appears in the reinforced model till the end of seismic waves; seismic damage of walls in the reinforced model is obviously lighter than that in the original model; dynamic responses at all observed points of the reinforced masonry are obviously less than those of the original model. Strains at all positions of the reinforced model are obviously smaller than those of the original model. From macroscopic and microscopic perspectives, the computational results prove that the reinforced proposal proposed in this paper can effectively improve the antiseismic performance of the masonry structure. (shrink)

Spanning the 19th and 20th centuries and identifying multiple waves of modernization, this book illustrates how principles originating in Chinese Confucianism have impacted the modernization of East Asia, especially in Korea. It also analyzes how such principles are exercised at personal, interpersonal and organizational levels. As modernization unfolds in East Asia, there is a rising interest in tradition of Confucianism and reconsider the relevance of Confucianism to global development. This book considers the actual historical significance of Confucianism in the modernization (...) of the three nations in this region, China, Korea, and Japan through the nineteenth century and early twentieth century to the aftermath of the end of World War II. Examining the existing literature dealing with how Confucianism has been viewed in connection with modernization, it provides insight into western attitudes towards Confucianism and the changes in perceptions relative to Asia in the very process of modernization itself. (shrink)