A prefrontal control system that is less mature than the limbic reward system in adolescence is thought to impede self-regulatory abilities, which could contribute to poor dietary choices and obesity. We, therefore, aimed to examine whether structural morphology of the prefrontal cortex and the amygdala are associated with dietary decisions and obesity in children and adolescents. Seventy-one individuals between the ages of 8–22 years participated in this study; each participant completed a computer-based food choice task and a T1- and T2-weighted (...) structural brain scans. Two indices of obesity were assessed, including age- and sex-specific body mass index and waist-to-height ratio. The behavioral task included rating 60 food stimuli for tastiness, healthiness, and liking. Based on each participant’s self-ratings, 100 binary food choices were then made utilizing a computer mouse. Dietary “self-control” was calculated as the proportion of trials where the individual chose the healthier food item over the total number of trials. Cortical thickness and amygdala subnuclei volumes were quantified using FreeSurfer 6.0 and CIT168 atlas, respectively. We found that WHtR was negatively associated with the thickness of bilateral superior frontal, left superior temporal, right insula, and right inferior temporal regions. We also found WHtR to be positively associated with the volume of the central nucleus region of the amygdala, after adjusting for the hemisphere, age, sex, and intracranial volumes. A similar data pattern was observed when BMIz was used. Moreover, we found that across all participants, thinner right superior frontal cortex and larger left CEN volumes predicted lower dietary self-control. These results suggest that differential development of the PFC and amygdala relate to obesity and dietary self-control. Further longitudinal studies are merited to determine causal relationships among altered PFC to amygdala neural circuitry, dietary self-control, and obesity. (shrink)

El ejercicio filosófico de raíz marxista en Chile tiene un capítulo escrito por los intelectuales comunistas de la década del 60 del siglo XX. Uno de ellos, Sergio Vuskovic, se abocó a discutir con las tesis althusserianas que identificaron la teorización de Marx como un antihumanismo teórico. Para oponerse a tal perspectiva, Vuskovic realiza una operación teórica al interior de la obra de Marx con el objetivo de afirmar la categoría de sujeto, así como la interna relación entre ejercicio teórico (...) y praxis socio-histórica. Chilean communist intellectuals of the 1960's wrote a chapter of the history of Marxist philosophy. One of them was Sergio Vuskovic who focused on discussing Marx's theories according to Althusser's thesis of anti-humanism. By affirming the subject category and the internal relationship between "theoretical operation" and socio-historical praxis within Marx's philosophy, Vuskovic opposes Althusser's perspective. (shrink)

Marc Crépon es director de investigación en el Centre National de la Recherche Scientifique y director del Departamento de Filosofía de l’École normale supérieure de París. Entre sus publicaciones se encuentran: La culture de la peur, I. Démocratie, identité, sécurité ; La culture de la peur, II. La guerre des civilisations ; Le consentement meurtrier ; La vocation de l’écriture ; La gauche c’est quand?.

So-called ‘facial’ cumshots, when a man ejaculates onto a woman’s face, are very common in pornography. While they are frequently said to be degrading and misogynistic, the fact that women are usually shown as enjoying this act should make us think again. Facials are instead rooted in male insecurity: of a fear that an aspect of how men orgasm—semen—is disgusting to women. By contrast, the fantasy, which pornography makes vivid, is that women might not just tolerate but celebrate and eroticize (...) both ejaculation and its product. The way mainstream pornography presents facials may often be misogynistic, but it does not have to be, and it is not always. -/- NOTE: This may not be a philosophy paper. My intention is to submit it to a sexuality studies journal. (shrink)

So-called `disentangled' truth-theories are supposed to prevent assumptions about the truth of statements in the object-language from inadvertently strengthening the background syntax. In earlier work, I proved some limitative results in an attempt to show that the strategy works, but those results leave several questions unanswered. We address some of them here. We also discuss a subtlety that has so far been overlooked in discussions of these theories.

In this paper I argue that some human reproductive genome editing interventions can be therapeutic in nature, and thus that it is false that all such interventions just create healthy individuals. I do this by showing that the conditions established by a therapy definition are met by certain reproductive genome editing interventions. I then defend this position against two objections: (a) reproductive genome editing interventions do not attain one of the two conditions for something to be a therapy, and (b) (...) some reproductive genome editing interventions are therapeutic but in a nonstandard way. In the Conclusion I call for a more nuanced discussion of the nature of reproductive genome editing interventions. (shrink)

Many people have sexual fantasies about being forced to have sex, or forcing someone to have sex. Several authors have argued that it is wrong to enjoy such fantasies: They lead to harm, or reinforce oppressive social structures, are liable to corrupt our character, or, mostly interestingly, are wrong in themselves, because they involve the eroticization of things that are wrong. I argue here that all such arguments fail properly to distinguish between fantasy and desire (despite authors' acknowledgement of that (...) distinction), and between objects of desire and sources of arousal. The broader significance of this point is also discussed. -/- This paper is intended, in part, as a defense of claims about sexual fantasy made at the end of "Does Pornography Presuppose Rape Myths?". (shrink)

RESUMEN El presente trabajo está dirigido a exponer elementos inherentes al modelo de superación profesional del tecnólogo de la salud en laboratorio clínico desde la integración ciencias básicas biomédicas-laboratorio. Entre los métodos teóricos empleados, el analítico-sintético permitió la determinación de los fundamentos epistemológicos y praxiológicos del proceso de superación, el inductivo-deductivo posibilitó la determinación de las categorías que surgen en el proceso investigativo, el sistémico estructural funcional para fundamentar el carácter de sistema del modelo y la modelación con la finalidad (...) de construirlo. Se concluye que se establecen como subsistemas del modelo, la proyección profesional de las ciencias básicas biomédicas, la contextualización profesional de la integración ciencias básicas biomédicas-laboratorio y la valoración contextual de la integración en el proceso de superación, lo que explica el proceso de superación del tecnólogo de la salud en laboratorio clínico. ABSTRACT This paper aims at setting out elements inherent to the health technologist in clinical laboratory’s professional training model from the integration of basic biomedical-laboratory sciences. Among the theoretical methods used, analysis-synthesis allowed establishing the epistemological and praxeological basis of the training process; the inductive-deductive method made it possible to determine the categories that result from the research process and the systemic-structural-functional method was used to support the system-like nature of the model and modelling with the end of building it. In conclusion, subsystems of the model are established: basic biomedical sciences professionals’ aims, professional conceptualization of the integration of basic biomedical-laboratory sciences and the contextual assessment of integration in the training process, which expounds the training process of the health technologist in clinical laboratory. (shrink)

El propósito fundamental del trabajo fue destacar la trascendencia social de las ciencias básicas biomédicas en la superación profesional de los tecnólogos en Laboratorio Clínico, egresados de la Facultad de Tecnología de la Salud de Camagüey. Se partió de las insuficiencias que influyen en el desempeño profesional de estos licenciados, y se justifica la importancia de las ciencias básicas biomédicas para el laboratorista clínico. Se concluyó que la ciencia y la tecnología son prácticas sociales que debe tener en cuenta en (...) su labor cotidiana el tecnólogo de la salud en Laboratorio Clínico y la necesidad de las ciencias básicas biomédicas en la superación profesional de estos tecnólogos ya que aportan los fundamentos científicos del proceder técnico en un laboratorio, lo cual permite capacitar un profesional no solo para llevar a cabo procederes, sino para comprender el porqué de los mismos. The main goal of this work was to highlight the social implications of the basic biomedical sciences in the professional training of the technologist in clinical laboratory graduated at the Health Technologic Faculty in Camaguey taking into account the insufficiencies in the professional performance of these specialists. It was evident that science and technology are social practices that the health technologist specialized in clinical laboratory has to take into account and the need of basic biomedical sciences in the professional development of these technologists because they offer the scientific basis of the technical procedure in a laboratory which allows the professional training not only to perform the procedures but also to understand the reason of them. (shrink)

El perfeccionamiento del desempeño profesional del laboratorista clínico constituye una necesidad, por lo que el objetivo de la investigación fue elaborar una estrategia para la superación profesional del tecnólogo de la salud en laboratorio clínico a partir de la integración con las ciencias básicas biomédicas. La estrategia se efectuó en la Facultad de Tecnología de la Salud de Camagüey. Su factibilidad fue valorada por expertos y la validación se llevó a cabo con un pre experimento pedagógico que se desarrolló en (...) el curso 2014- 2015. Los resultados corroboran su efectividad. The improvement in professional performance of clinical lab technicians is a continuous necessity. As such, the aim of the research was to develop a strategy for achieving improved professional development for health technologists specialized in clinical laboratory practices through integration with basic biomedical sciences. The study was conducted at the School of Health Technology in Camagüey. Its feasibility was assessed by experts and validation was performed with a pre-pedagogical experiment that developed during the 2014- 2015 academic year. Results confirm the effectiveness of the strategy as developed within the scope of the study. (shrink)

It has long been recognized that cancer onset and progression represent a type of reversion to an ancestral quasi‐unicellular phenotype. This general concept has been refined into the atavistic model of cancer that attempts to provide a quantitative analysis and testable predictions based on genomic data. Over the past decade, support for the multicellular‐to‐unicellular reversion predicted by the atavism model has come from phylostratigraphy. Here, we propose that cancer onset and progression involve more than a one‐off multicellular‐to‐unicellular reversion, and are (...) better described as a series of reversionary transitions. We make new predictions based on the chronology of the unicellular‐eukaryote‐to‐multicellular‐eukaryote transition. We also make new predictions based on three other evolutionary transitions that occurred in our lineage: eukaryogenesis, oxidative phosphorylation and the transition to adaptive immunity. We propose several modifications to current phylostratigraphy to improve age resolution to test these predictions. Also see the video abstract here: https://youtu.be/3unEu5JYJrQ. (shrink)

Objeto o sujeto de derechos Nature: Object or subject of rights Cartay, Belkis Acerca de la racionalidad científica: Feyerabend y los límites de la argumentación Scientific rationality, Feyerabend and the limits of the argument Castrejón, Gilberto El embrión es vida humana The embryo is human life Chacín, Ronald Ética y política: Las consecuencias prácticas de la modernización en la óptica de una acción comunicativa Ethics and politics: Practical consequences of modernization from the viewpoint of a comunicative act De La Vega, (...) Marta La libertad de expresión: De la doctrina a la ley The freedom of expresion: From doctrine to law Belandria, Margarita y González, Javier Globalización y "Glocalización" frente al debate postmoderno Globalization and "Glocalizacion" in the post-moderne debate Mora García, José Pascual El Derecho en "El Alcalde de Zalamea" Law in "The Mayor of Zalamea" Parodi Remón, Carlos Interdisciplinares La palabra y su universo de sentido Word and its universe of sense Espar, Teresa Procesos existenciales en el ritmo de la poesía Existential processes in the thythm of poetry Hocevar, Drina Traducciones Karl Löwith "Mi vida en Alemania antes y después de 1933" Vasquez, Eduardo. (shrink)

Alberto Sobrado, Carlos González-García y María Ruz Centro de Investigación Mente, Cerebro y Comportamiento, Universidad de Granada, España El término … Read More →.

Here some reflections from Leonardo Polo about basic questions of educative philosophy are presented: the family, affection, imagination, interest, ethic and the global orientation. He points out the importance of the idea that belongs to the family to obtain the affective stability of the son.

Following González Vergara (2006a, 2009, 2012), the presence of the morpheme se in Spanish is explained by a lexical phenomenon that modifies the logical structure of sentences in which it appears. This phenomenon decreases the importance of the Actor and favors the Undergoer. According to this proposal, this phenomenon expresses itself, in most of the Spanish sesentences, as a lexical rule that makes unspecific the highest ranking argument. Taking the above as a basis, this paper explores and proposes explanations for (...) se alternating verbs of the type of matar(se), morir(se), dormir(se), despertar(se), terminar(se), adelgazar(se), engordar(se), envejecer(se), mejorar(se), controlar(se), crecer(se) y aparecer(se) in the framework of the Role and Reference Grammar. (shrink)

The paper makes a twofold contribution. Firstly, it advances a preliminary account of the conditions that need to obtain for constitutional rights to be democratic. Secondly, in so doing, it defends precommitment-based theories from a criticism raised by Jeremy Waldron—namely, that constitutional rights do not become any more democratic when they are democratically adopted, for the people could adopt undemocratic policies without such policies becoming democratic as a result. The paper shows that the reductio applies to political rights, yet not (...) to non-political rights, such as reproductive, environmental, or privacy rights. The democratic status of the former is process-independent. The latter, by contrast, are democratic precisely when they are adopted by democratic means. (shrink)

We start from a line of research that studies the prophetic knowledge in Islamic philosophy of the classical period, as a symbol and a promise of perfect knowledge which can be reached by man. And from this place, we ask after the meaning of perfect knowledge in Suarez’s epistemology. We will discuss a number of issues that will emerge from the analysis of the faculty of imagination inserted into an intentional conception of knowledge supported on two pillars: a theory of (...) representation, explained by the mediation of intentional species and a theory of understanding, ending in judicative judgment as a path to truth. The depth and branching statements that present problems will cause us to focus on the last one. (shrink)

The present paper has a negative aim and a positive aim, both limited in the present context to a sketch or outline. The negative aim, today less controversial, is to show that Aristotle’s theory of final causality has little or nothing to do with the teleology rejected by modern science and that, therefore, far from having been rendered obsolete, it has yet to be fully understood. This aim will be met through the identification and brief discussion of some key points (...) on which Aristotle’s theory differs from teleology as still commonly understood. The positive aim is more controversial as it proposes that we take an ontology of life as the proper context for understanding the significance and nature of final causation in Aristotle. The argument for final causation, in other words, is that, without it, we would lose the phenomenon of life and, indeed, of nature altogether, reducing nature to the inanimate and mechanical. (shrink)

Contemporary scholars have generally labelled Adolf Reinach, a founding member of early phenomenology’s Göttingen Circle, a Platonist. Because Reinach conceives of states of affairs as neither real nor ideal, as involved with timeless essences and necessary logical laws, many have hastily concluded that states of affairs are Platonic entities. In this essay, I analyse Barry Smith’s argument that Reinach is a Platonist. Smith’s widely accepted argument often becomes utilised to show that Reinach and other phenomenologists, including Husserl, are Platonic realists (...) (or, simply, Platonists). A closer look at Reinach’s text indicates, however, that he is notcommitted to Platonic realism. (shrink)

. In this paper we present a proposal that (i) could validate more relations in the square than those allowed by classical logic (ii) without a modification of canonical notation neither of current symbolization of categorical statements though (iii) with a different but reliable semantics.

The present article provides an overview of the different positions throughout history on the connections between science and religion. We expose the diffi culty to classify these connections and the defi ciency in the taxonomic proposals. This study is intended to revise this interplay from the perspective of the impertinences committed to each other, as well as from the benefi ts that one has received from the other. From this point of view, we can get a glimpse of a more (...) complex and rich scene than that offered by a simple classifi cation. We also reveal that, when one of these fi elds ignores what pertains to the other and fi nally rejects it, it ends up either taking its role or accepting it as its own, but in a poor or completely unfocussed way. The consequence of this is unavoidably scepticism. (shrink)

Christianity shaped Europe and Europe shaped Christianity until the Enlightenment broke of from earlier institutions and dogmas. Was this to eliminate them or to bring them to a better realization? The relationship of Modernity to Christianity has been interpreted in different ways: as an alternative. as a better realization or as a secularized continuation. Looking to the future, can Christianity exist without Europe, an can Europe exist without Chistianity? After listing what are the values and undeniable achievements of Christianity, without (...) wich Europe would cease to be what it has been, the author highlights the contribution of Christianity to a new use of reason, and he concludes with a reflection on the relationship between Christianity and his-tory (continuity-innovation, sinking-rebirth). (shrink)