Beta‐oxidation of fatty acids and detoxification of reactive oxygen species are generally accepted as being fundamental functions of peroxisomes. Additionally, these pathways might have been the driving force favoring the selection of this compartment during eukaryotic evolution. Here we performed phylogenetic analyses of enzymes involved in beta‐oxidation of fatty acids in Bacteria, Eukaryota, and Archaea. These imply an alpha‐proteobacterial origin for three out of four enzymes. By integrating the enzymes' history into the contrasting models on the origin of eukaryotic cells, (...) we conclude that peroxisomes most likely evolved non‐symbiotically and subsequent to the acquisition of mitochondria in an archaeal host cell. (shrink)

At first glance the three eukaryotic protein translocation machineries – the ER‐associated degradation (ERAD) transport apparatus of the endoplasmic reticulum, the peroxisomal importomer and SELMA, the pre‐protein translocator of complex plastids – appear quite different. However, mechanistic comparisons and phylogenetic analyses presented here suggest that all three translocation machineries share a common ancestral origin, which highlights the recycling of pre‐existing components as an effective evolutionary driving force.Editor's suggested further reading in BioEssays ERAD ubiquitin ligases Abstract.

The objects we encounter in ordinary life and scientific practice - cars, trees, people, houses, molecules, galaxies, and the like - have long been a fruitful source of perplexity for metaphysicians. The Structure of Objects gives an original analysis of those material objects to which we take ourselves to be committed in our ordinary, scientifically informed discourse. Koslicki focuses on material objects in particular, or, as metaphysicians like to call them "concrete particulars", i.e., objects which occupy a single region of (...) space-time at each time at which they exist and which have a certain range of properties that go along with space-occupancy, such as weight, shape, color, texture, and temperature. The Structure of Objects focuses in particular on the question of how the parts of such objects, assuming that they have parts, are related to the wholes which they compose. (shrink)

Normativism in the theory of meaning and content is the view that linguistic meaning and/or intentional content are essentially normative. As both normativity and its essentiality to meaning/content can be interpreted in a number of different ways, there is now a whole family of views laying claim to the slogan “meaning/content is normative”. In this essay, we discuss a number of central normativist theses, and we begin by identifying different versions of meaning normativism, presenting the arguments that have been put (...) forth for and against them. (shrink)

In _Form, Matter, Substance_, Kathrin Koslicki defends a hylomorphic analysis of concrete particular objects (e.g., living organisms). The Aristotelian doctrine of hylomorphism holds that those entities that fall under it are compounds of matter (hulē) and form (morphē or eidos). Koslicki argues that a hylomorphic analysis of concrete particular objects is well-equipped to compete with alternative approaches when measured against a wide range of criteria of success. A successful application of the doctrine of hylomorphism to the special case of (...) concrete particular objects, however, hinges on how hylomorphists conceive of the matter composing a concrete particular object, its form, and the hylomorphic relations which hold between a matter-form compound, its matter and its form. Through the detailed answers to these questions Koslicki develops in this book, matter-form compounds, despite their metaphysical complexity, emerge as occupying the privileged ontological status traditionally associated with substances, due in particular to their high degree of unity. (shrink)

As meaning's claim to normativity has grown increasingly suspect the normativity thesis has shifted to mental content. In this paper, we distinguish two versions of content normativism: 'CE normativism', according to which it is essential to content that certain 'oughts' can be derived from it, and 'CD normativism', according to which content is determined by norms in the first place. We argue that neither type of normativism withstands scrutiny. CE normativism appeals to the fact that there is an essential connection (...) between content and correctness conditions. But, we argue, this fact is by itself normatively innocent, and attempts to add a normative dimension via the normativity of belief ultimately fail. CD normativism, in turn, falls prey to the 'dilemma of regress and idleness': the appeal to rules either leads to some form of regress of rules, or the notion of rule-following is reduced to an idle label. We conclude by suggesting that our arguments do not support naturalism: it is a mistake to assume that normativism and naturalism are our only options. (shrink)

Non-modalists about essence reject the idea that metaphysical modality is prior to essence, e.g., in the sense that the latter can be reduced to or defined in terms of the former. On the contrary, according to these theorists, the explanation, if anything, proceeds in the opposite direction: metaphysical modality does not explain, but is instead explained in terms of, essence. Thus, for non-modalists like Aristotle, Kit Fine and E. J. Lowe, one of the primary theoretical roles of essence is to (...) provide an explanatory basis for metaphysical necessity and possibility. This chapter explores a range of different types of explanatory connections which raise the question of how the non-modalist’s program of explaining metaphysical modality in terms of essence is best carried out. The considerations advanced in this chapter suggest that non-modalists must proceed by way of a non-logical case-by-case engagement with specific cases, since no logical “one-size-fits- all” strategy appears to be available. (shrink)

Does the notion of ground, as it has recently been employed by metaphysicians, point to a single unified phenomenon? Jonathan Schaffer holds that the phenomenon of grounding exhibits the unity characteristic of a single genus. In defense of this hypothesis, Schaffer proposes to take seriously the analogy between causation and grounding. More specifically, Schaffer argues that both grounding and causation are best approached through a single formalism, viz., that utilized by structural equation models of causation. In this paper, I present (...) several concerns which suggest that the structural equation model does not transfer as smoothly from the case of causation to the case of grounding as Schaffer would have us believe. If it can in fact be shown that significant differences surface in how the formalism in question applies to the two types of phenomena in question, Schaffer’s attempt at establishing an analogy between grounding and causation has thereby been weakened and, as a result, the application of the Unity Hypothesis to the case of grounding once again stands in need of justification. (shrink)

Today, many philosophers think that perceptual experiences are conscious mental states with representational content and phenomenal character. Subscribers to this view often go on to construe experience more precisely as a propositional attitude sui generis ascribing sensible properties to ordinary material objects. I argue that experience is better construed as a kind of belief ascribing 'phenomenal' properties to such objects. A belief theory of this kind deals as well with the traditional arguments against doxastic accounts as the sui generis view. (...) Moreover, in contrast to sui generis views, it can quite easily account for the rational or reason providing role of experience. (shrink)

Die Arbeit wendet sich einem zentralen Problem der Modernen Sprachphilosophie zu. Mit Kripkes 'Wittgenstein' hat die Sprachphilosophie einen neuen Slogan erhalten: Beudeutung ist normativ. Dass die Sprache nicht naturlich, sondern konventionell sei, gehort dabei seit der griechischen Sophistik zu den Binsenweisheiten dieses Zweigs der Philosophie. Sehen wir jedoch mit Wittgenstein sprachliche Bedeutung als durch den Gebrauch sprachlicher Ausdrucke bestimmt an, wird daraus schnell die These, es seien die 'Regeln' fur den Gebrauch solcher Ausdrucke, die deren Bedeutung bestimmen, die - mit (...) anderen Worten - bestimmen, was korrekter und was inkorrekter Gebrauch ist. Als Normativthese reformuliert, findet die antike Binsenweisheit so auch in der aktuellen Kontroverse breiten Konsens, eint sie Sprachphilosophen unterschiedlicher Couleur. In Auseinadnersetzung u.a. mit Dummett, Kripke, McDowell, Putnam und Wittgenstein arbeitet Kathrin Gluer nicht nur heraus, dass dieser Konsens aufgrund der Unterschiedlichkeit der dabei in Anspruch genommenen Normativitatsverstandnisse ein scheinbarer isr. Daruber hinaus argumentiert sie, an der Normativitatsthese selbst sei so gut wie alles falsch. Auf der Grundlage eines teilweise an der Philosophie Davidsons orientierten nicht-reduktiven Verstandnisses von Bedeutung und Intentionalitat zeige sich vielmehr, dass Normen oder Regeln nicht in den elementaren "Zirkel" intentionaler Begriffe gehoren. Bei der Untersuchung dieser Fragen erweisen sich Sprachphilosophie, Handlungstheorie und Philosophie des Geistes als untrennbar miteinander verbunden. (shrink)

A significant reorientation is currently under way in analytic metaphysics, away from an almost exclusive focus on questions of existence and towards a greater concentration on questions concerning the dependence of one type of phenomenon on another. Surprisingly, despite the central role dependence has played in philosophy since its inception, interest in a systematic study of this concept has only recently surged among contemporary metaphysicians. In this paper, I focus on a promising account of ontological dependence in terms of a (...) non-modal and sufficiently constrained conception of essence developed by Kit Fine. I argue that even this essentialist account is, as it stands, not fine-grained enough to recognize different varieties of dependence which ought to be distinguished even within the realm of ontology. In some cases, an entity may be ontologically dependent on its essential constituents out of which it is constructed; but in other cases, an entity may be ontologically dependent on another for a different reason. A framework which glosses over these differences does not offer a proper diagnosis of why one entity ontologically depends on another. (shrink)

According to some phenomenologists, a tool can be experienced as incorporated when, as a result of habitual use or deliberate practice, someone is able to manipulate it without conscious effort. In this article, we specifically focus on the experience of expertise tool use in elite sport. Based on a case study of elite rope skipping, we argue that the phenomenological concept of incorporation does not suffice to adequately describe how expert tool users feel when interacting with their tools. By analyzing (...) a combination of insights gained from participant observation of 11 elite rope skippers and autoethnographic material from one former elite skipper, we take some initial steps toward the development of a more nuanced understanding of the concept of incorporation; one that is able to accommodate the experiences of expert tool users. In sum, our analyses indicate that the possibility for experiencing a tool as incorporated depends on the existence of an extraordinary kind of relationship between th... (shrink)

Is it possible to find an ethical and generative way to speak about the ‘work’ of Indigenous art? Regardless of what prohibitions exist to protect sacred knowledge from the gaze of Western eyes, Indigenous work is circulating; it is being read, misread, interpreted, misinterpreted and otherwise known. How can a non-Indigenous person ‘speak’ about Indigenous art without reducing it to the diagram, collapsing it into Western modes of knowing, or intruding into the domain of restricted cultural information? Given the lessons (...) of the Indigenous cultural practices, I propose that the work of art is performative and not merely representational. Through attention to the operation of rhythm in Kathleen Petyarre’s paintings, I propose to reconfigure contemporary understandings of performativity. In this formulation I will argue that in the dynamic productivity of the performative act, the world intrudes into practice, and in a double movement, practice casts its effects back towards the world. In this way I suggest that just as life gets into images, so imaging also produces reality. This mutual reflection is the work of art. (shrink)

'Wessen Wissen?' ist einerseits eine Frage nach Akteur-innen, Körpern, Materialien und Technologien, die in künstlerischen Produktions- und Wissensprozessen miteinander interagieren. Diese lassen sich als Übersetzungen und Transformationen beschreiben, in denen Künstler-nnen längst nicht mehr die einzigen Subjekte des Wissens sind. Denn in den künstlerischen Praktiken des Entwerfens, Skizzierens, Modellierens, Probens und Experimentierens entfalten Medien und Materialien ihre je eigene agentielle Kraft. 'Wessen Wissen?' ist andererseits eine Frage nach der Heterogenität von Wissensformationen in ihren partikularen und partialen Perspektiven, also nach situated (...) knowledges. Damit wird die Vorstellung einer allgemeingültigen, körperlosen, neutralen Objektivität bestritten. Im Gegenzug nimmt das situierte Wissen der Künste für sich in Anspruch, Erkenntnisse hervorzubringen und zur Verfügung zu stellen. Es steht demnach für verkörperte Kenntnisse, die in das Feld des zugelassenen und legitimen Wissens kritisch intervenieren. (shrink)

This essay provides an opinionated survey of some recent developments in the literature on ontological dependence. Some of the most popular definitions of ontological dependence are formulated in modal terms; others in non-modal terms (e.g., in terms of the explanatory connective, ‘because’, or in terms of a non-modal conception of essence); some (viz., the existential construals of ontological dependence) emphasise requirements that must be met in order for an entity to exist; others (viz., the essentialist construals) focus on conditions that (...) must be satisfied in order for an entity to be the very entity it is at each time at which it exists; some are rigid, in the sense that they concern a relation between particular entities; others are generic, in the sense that they involve only a relation between an entity and some entities or other, which bear certain characteristics. I identify three potential measures of success with respect to which these different definitions of ontological dependence can be evaluated and consider the question of how well they in fact meet these desiderata. I end by noting that certain challenges face even the most promising essentialist construals of ontological dependence. (shrink)

Epigenetic markers could potentially be used for risk assessment in risk-stratified population-based cancer screening programmes. Whereas current screening programmes generally aim to detect existing cancer, epigenetic markers could be used to provide risk estimates for not-yet-existing cancers. Epigenetic risk-predictive tests may thus allow for new opportunities for risk assessment for developing cancer in the future. Since epigenetic changes are presumed to be modifiable, preventive measures, such as lifestyle modification, could be used to reduce the risk of cancer. Moreover, epigenetic markers (...) might be used to monitor the response to risk-reducing interventions. In this article, we address ethical concerns related to personal responsibility raised by epigenetic risk-predictive tests in cancer population screening. Will individuals increasingly be held responsible for their health, that is, will they be held accountable for bad health outcomes? Will they be blamed or subject to moral sanctions? We will illustrate these ethical concerns by means of a Europe-wide research programme that develops an epigenetic risk-predictive test for female cancers. Subsequently, we investigate when we can hold someone responsible for her actions. We argue that the standard conception of personal responsibility does not provide an appropriate framework to address these concerns. A different, prospective account of responsibility meets part of our concerns, that is, concerns about inequality of opportunities, but does not meet all our concerns about personal responsibility. We argue that even if someone is responsible on grounds of a negative and/or prospective account of responsibility, there may be moral and practical reasons to abstain from moral sanctions. (shrink)

Implicit bias is one of the most successful cases in recent memory of an academic concept being translated into practice. Its use in the National Science Foundation ADVANCE program—which seeks to promote gender equality in STEM careers through institutional transformation—has raised fundamental questions about organizational change. How do advocates translate theories into practice? What makes some concepts more tractable than others? What happens to theories through this translation process? We explore these questions using the ADVANCE program as a case study. (...) Using an inductive, theory-building approach and combination of computational and qualitative methods, we investigate how the concept of implicit bias was translated into practice through the ADVANCE program and identify five key features that made implicit bias useful as a change framework in the academic STEM setting. We find that the concept of implicit bias works programmatically because it is demonstrable, relatable, versatile, actionable, and impartial. While enabling the concept’s diffusion, these characteristics also limit its scope. We reflect on implications for gender theories of organizational change and for practitioners. (shrink)

Some theories of linguistic meaning, such as those of Paul Grice and David Lewis, make appeal to higher–order thoughts: thoughts about thoughts. Because of this, such theories run the risk of being empirically refuted by the existence of speakers who lack, completely or to a high degree, the capacity of thinking about thoughts. Research on autism during the past 15 years provides strong evidence for the existence of such speakers. Some persons with autism have linguistic abilities that qualify them as (...) speakers, but manifest a severely impaired capacity to understand what it is to have beliefs. (shrink)

Barbara Bolt takes the most relevant of Heidegger's texts, including his most famous work, 'Being and Time', and sets out ways of thinking about art in a post-medium, digital, technocratic and post-human age.

Essences have been assigned important but controversial explanatory roles in philosophical, scientific, and social theorizing. Is it possible for the same organism to be first a caterpillar and then a butterfly? Is it impossible for a human being to transform into an insect like Gregor Samsa does in Franz Kafka’s The Metamorphosis? Is it impossible for Lot’s wife to survive being turned into a pillar of salt? Traditionally, essences (or natures) have been thought to help answer such central questions about (...) existence, identity, persistence, and modality. These questions are not only of great philosophical interest, they also are of great interest to society at large. This Handbook surveys the state of the art on essence. Core issues about essence are discussed in 33 chapters, all of them written exclusively for this volume by leading experts. (shrink)

The question “What is it to be an artifact?” must be distinguished from the question “What is it to be an artifact of kind K?”. Failure to distinguish between these two questions leads to an exaggeration of the role of intentions in the philosophy of artifacts. We accept that intentions are necessary to de ne the category of artifacts, but we reject the view that intentions are constitutive of what makes something a specic kind of artifact. In the first part (...) of this paper, we discuss a series of cases involving what we call “faith-based artifacts” which often exhibit a social dimension. These cases, we argue, constitute counterexamples to the thesis that something is an artifact of a specific kind if it was produced with the intention that it be an object of that kind. In the second part of the paper, we explain how a capacity-based approach to artifacts, by contrast, can accommodate faith-based artifacts. In the last section, we address an objection to the capacity-based approach. (shrink)

The aim of this article is to illustrate how a belief in the existence of kinds may be justified for the particular case of natural kinds: particularly noteworthy in this respect is the weight borne by scientific natural kinds (e.g., physical, chemical, and biological kinds) in (i) inductive arguments; (ii) the laws of nature; and (iii) causal explanations. It is argued that biological taxa are properly viewed as kinds as well, despite the fact that they have been by some alleged (...) to be individuals. Since it turns out that the arguments associated with the standard Kripke/Putnam semantics for natural kind terms only establish the non-descriptiveness of natural kind terms and not their rigidity, the door is open to analyze these terms as denoting traditional predicate-extensions. Finally, special issues raised by physical and chemical kinds are considered briefly, in particular impurities, isotopes and the threat of incommensurability. (shrink)

In this book, Kathrin Gl¨uer carefully outlines Donald Davidson's principal claims and arguments, and discusses them in some detail, providing a concise, systematic introduction to all the main elements of Davidson's philosophy.

Our knowledge of the human brain and the influence of pharmacological substances on human mental functioning is expanding. This creates new possibilities to enhance personality and character traits. Psychopharmacological enhancers, as well as other enhancement technologies, raise moral questions concerning the boundary between clinical therapy and enhancement, risks and safety, coercion and justice. Other moral questions include the meaning and value of identity and authenticity, the role of happiness for a good life, or the perceived threats to humanity. Identity and (...) authenticity are central in the debate on psychopharmacological enhancers. In this paper, I first describe the concerns at issue here as extensively propounded by Carl Elliott. Next, I address David DeGrazia’s theory, which holds that there are no fundamental identity-related and authenticity-related arguments against enhancement technologies. I argue, however, that DeGrazia’s line of reasoning does not succeed in settling these concerns. His conception of identity does not seem able to account for the importance we attach to personal identity in␣cases where personal identity is changed through enhancement technology. Moreover, his conception of authenticity does not explain the reason why we find inauthentic values objectionable. A broader approach to authenticity can make sense of concerns about changes in personal identity by means of enhancement technologies. (shrink)

This paper evaluates six contenders which might be invoked by essentialists in order to meet Quine’s challenge, viz., to provide necessary and sufficient conditions for the crossworld identity of individuals: (i) an object’s qualitative character; (ii) matter; (iii) origins; (iv) haecceities or primitive non-qualitative thisness properties; (v) “world-indexed properties”; and (iv) individual forms. The first three candidates, I argue, fail to provide conditions that are both necessary and sufficient for the crossworld identity of individuals; the fourth and fifth criteria are (...) open to the charge that they do not succeed in meeting Quine’s demand in an explanatorily adequate fashion. On balance, then, individual forms, or so I propose, deserve to be taken very seriously as a possible response to Quine’s challenge, especially by neo-Aristotelians who are already committed to a hylomorphic conception of composite concrete particular objects for other reasons. Theorists who also accept a non-modal conception of essence, i.e., a conception according to which essence is not reducible to modality, in addition face the further difficult task, over and above what is required to meet Quine’s challenge, of having to explain how an object’s de re modal profile in some way follows from facts about its essence. Haecceities and world-indexed properties, as I indicate, are unlikely to be of much help with respect to this second challenge, while the forms of hylomorphic compounds are in fact well-suited for this purpose. (shrink)

This chapter reviews several varieties of grounding skepticism as well as responses that have been proposed by grounding enthusiasts to considerations raised by grounding skeptics. Grounding skeptics, as I conceive of them here, are theorists who belong to one of the following two schools of thought. “Old-school” grounding skeptics doubt the theoretical utility of the grounding idiom by denying one of its presuppositions, viz., that this notion is at least intelligible or coherent. “Second-generation” grounding skeptics call into question the theoretical (...) utility of the grounding idiom for other reasons; their skeptical doubts tend to focus on one of the following three purported theoretical virtues grounding enthusiasts ascribe to their idiom: (i) its alleged power to unify an apparently heterogeneous collection of phenomena; (ii) its alleged power to capture and/or elucidate the distinction between the fundamental and the non-fundamental; or (iii) the alleged metaphysical (as opposed to mind-dependent, epistemic, or psychological) utility of grounding claims. Grounding enthusiasts have already formulated responses to many of the objections described in this chapter. At this point, however, it is fair to say that the state of the literature is still evolving, and no conclusive judgment can therefore be reached as of yet as to whether grounding enthusiasts or grounding skeptics have gained the upper hand in these debates. In the meantime, though, grounding skeptics continue to maintain that the classification of factual and/or nonfactual connections under the rubric of grounding does not really help us illuminate the nature of the connections at issue; instead, from the view of the grounding skeptic, we are better off studying these various connections separately and in their own right. (shrink)

This inaugural lecture, delivered on 17 November 2021 at the University of Neuchâtel, addresses the question: Are material objects analyzable into more basic constituents and, if so, what are they? It might appear that this question is more appropriately settled by empirical means as utilized in the natural sciences. For example, we learn from physics and chemistry that water is composed of H2O-molecules and that hydrogen and oxygen atoms themselves are composed of smaller parts, such as protons, which are in (...) turn composed of yet smaller parts, such as quarks, and so on. While the question at the center of this lecture might thus appear to fall more appropriately into the empirical domain of natural science, I argue that metaphysics in fact has an important role to play in determining how best to answer the question before us. More concretely, I propose that the Aristotelian doctrine of hylomorphism, when appropriately interpreted, provides the best metaphysical answer to the question of whether and how material objects are analyzable into more basic constituents. Hylomorphism holds that those entities to which this doctrine applies are, in some sense, compounds of matter (“hylē”) and form (“morphē” or “eidos”). Thus, the title of this lecture, “Form, Matter, Substance”, refers to the claim that lies at the center of the doctrine of hylomorphism, as applied to the domain of material objects, namely that sensible substances are the result of combining matter and form in the right sort of way; or, for short, “form + matter = substance”. I begin in Section II by providing some historical background which brings out Aristotle’s motivations for proposing the doctrine of hylomorphism in the context of his analysis of change. Section III turns to some of the main features of the contemporary hylomorphic theory I have defended especially in Koslicki (2008) and Koslicki (2018). Section IV discusses some challenging questions concerning artifacts which arise for both hylomorphic and other approaches to the metaphysics of concrete particular objects. Section V concludes by summarizing why, as contemporary metaphysicians, we should prefer a hylomorphic theory over its competitors as an analysis of concrete particular objects that is compatible with our current scientific understanding of the world. (shrink)

Saul Kripke’s thesis that ordinary proper names are rigid designators is supported by widely shared intuitions about the occurrence of names in ordinary modal contexts. By those intuitions names are scopeless with respect to the modal expressions. That is, sentences in a pair like (a) Aristotle might have been fond of dogs (b) Concerning Aristotle, it is true that he might have been fond of dogs will have the same truth value. The same does not in general hold for definite (...) descriptions. If we, like Kripke, account for this difference by means of the intensions of names and descriptions, we have to conclude that names do not in general have the same intension as any normal, identifying description. However, the difference in scope behavior between names and description can be accounted for alternatively by appeal to the semantics of the modal expressions. On the account we suggest, dubbed ‘relational modality’, simple singular terms, like proper names, contribute to modal contexts simply by their actual world reference, not by their (standard) intension. The relational modality account turns out to be fully equivalent with the rigidity account when it comes to truth of modal and non-modal sentences (with respect to the actual world), and hence supports the same basic intuitions. Given an alternative definition of consequence for relational modality, and a restriction to models with reflexive accessibility relations and non-empty world-bound domains, relational modality also turns out to be model theoretically equivalent with rigidity semantics with respect to logical consequence. Here we introduce the semantics, give the truth definition for relational modality models, and prove the equivalence results. (shrink)

As an analogy, triangulation was introduced into the philosophy of mind and language in Donald Davidson's 1982 paper ‘Rational animals’. The analogy is used to support the claim that linguistic communication not only suffices to show that a creature is a rational animal in the sense of having propositional thoughts, but that it is necessary as well: ‘rationality is a social trait. Only communicators have it’. The triangulation argument employs the premise that in order to have any propositional thought whatsoever, (...) a creature needs to have the concept of objective truth. To have this concept, however, it must stand in certain relations of interaction not only with objects or events in the world but also with other creatures sufficiently like itself. The most simple such situation involves a ‘triangle’ of two creatures interacting with each other and an object or event in the world. (shrink)

Emotion Review, Volume 14, Issue 1, Page 84-95, January 2022. Emotional stimuli such as images, words, or video clips are often used in studies researching emotion. New sets are continuously being published, creating an immense number of available sets and complicating the task for researchers who are looking for suitable stimuli. This paper presents the KAPODI-database of emotional stimuli sets that are freely available or available upon request. Over 45 aspects including over 25 key set characteristics have been extracted and (...) listed for each set. The database facilitates finding of and comparison between individual sets. It currently contains sets published between 1963 and 2020. A searchable online version allows users to select specific set characteristics and to find matching sets accordingly, as well as to add new published sets. (shrink)

According to intentionalism, perceptual experience is a mental state with representational content. When it comes to the epistemology of perception, it is only natural for the intentionalist to hold that the justificatory role of experience is at least in part a function of its content. In this paper, I argue that standard versions of intentionalism trying to hold on to this natural principle face what I call the “defeasibility problem”. This problem arises from the combination of standard intentionalism with further (...) plausible principles governing the epistemology of perception: that experience provides defeasible justification for empirical belief, and that such justification is best construed as probabilification. After exploring some ways in which the standard intentionalist could deal with the defeasibility problem, I argue that the best option is to replace standard intentionalism by what I call “phenomenal intentionalism”. Where standard intentionalism construes experiences as of p as having the content p, phenomenal intentionalism construes experiences as of p as having “phenomenal” or “looks contents”: contents of the form Lp. (shrink)

It is common to think of essence along modal lines: the essential truths, on this approach, are a subset of the necessary truths. But Aristotle conceives of the necessary truths as being distinct and derivative from the essential truths. Such a non-modal conception of essence also constitutes a central component of the neo-Aristotelian approach to metaphysics defended over the last several decades by Kit Fine. Both Aristotle and Fine rely on a distinction between what belongs to the essence proper of (...) an object and what merely follows from the essence proper of an object. In order for this type of approach to essence and modality to be successful, we must be able to identify an appropriate consequence relation which in fact generates the result that the necessary truths about objects follow from the essential truths. I discuss some proposals put forward by Fine and then turn to Aristotle’s account: Aristotle’s central idea, to trace the explanatory power of definitions to the causal power of essences has the potential to open the door to a philosophically satisfying response to the question of why certain things are relevant, while others are irrelevant, to the nature or essence of entities. If at all possible, it would be desirable for example to have something further to say by way of explanation to such questions as ‘Why is the number 2 completely irrelevant to the nature of camels?’. (shrink)

This paper provides a detailed examination of Kit Fine’s sizeable contribution to the development of a neo-Aristotelian alternative to standard mereology; I focus especially on the theory of ‘rigid’ and ‘variable embodiments’, as defended in Fine 1999. Section 2 briefly describes the system I call ‘standard mereology’. Section 3 lays out some of the main principles and consequences of Aristotle’s own mereology, in order to be able to compare Fine’s system with its historical precursor. Section 4 gives an exposition of (...) Fine’s theory of embodiments and goes on to isolate a number of potential concerns to which this account gives rise. In particular, I argue that (i) Fine’s theory threatens to proliferate primitive sui generis relations of parthood and composition, whose characteristics must be stipulatively imposed on them, relative to particular domains; (ii) given its ‘superabundance’ of objects, Fine’s system far outstrips the (arguably) already inflated ontological commitments of standard mereology; and (iii) there is a legitimate question as to why we should consider Fine’s primitive and sui generis relations of parthood and composition to be genuinely mereological at all, given their formal profile. These three objections lead me to conclude that we ought to explore other avenues that preserve the highly desirable, hylomorphic, features of Fine’s mereology, while avoiding its methodological and ontological excesses. (shrink)

In a difficult but fascinating passage in Metaphysics Z.17, Aristotle puts forward a proposal, by means of a regress argument, according to which a whole or matter/form-compound is one or unified, in contrast to a heap, due to the presence of form or essence. This proposal gives rise to two central questions: (i) the question of whether form itself is to be viewed, literally and strictly speaking, as part of the matter/form-compound; and (ii) the question of whether form is to (...) be regarded as itself having parts. It is argued that both questions may be answered affirmatively, without giving rise to a regress worry. (shrink)

Concrete particular objects (e.g., living organisms) figure saliently in our everyday experience as well as our in our scientific theorizing about the world. A hylomorphic analysis of concrete particular objects holds that these entities are, in some sense, compounds of matter (hūlē) and form (morphē or eidos). The Grounding Problem asks why an object and its matter (e.g., a statue and the clay that constitutes it) can apparently differ with respect to certain of their properties (e.g., the clay’s ability to (...) survive being squashed, as compared to the statue’s inability to do so), even though they are otherwise so much alike. In this paper, I argue that a hylomorphic analysis of concrete particular objects, in conjunction with a non-modal conception of essence of the type encountered for example in the works of Aristotle and Kit Fine, has the resources to yield a solution to the Grounding Problem. (shrink)

This paper critically examines the implications of state efforts to expand prescriptive authority of pharmacists, which will allow them to prescribe various types of hormonal contraceptives. With this expansion, women no longer need to see a physician before being prescribed such contraceptives, but instead, they must answer self-assessment questionnaires at the pharmacy to ensure that their chosen method is safe and appropriate. This paper argues that while these measures to expand pharmacists’ prescriptive authority will surely meet the stated goal to (...) increase access to hormonal contraceptives, the measures may have detrimental consequences that have largely been downplayed. Studies consistently show that the OB-GYN is a significant primary care provider identified by young female patients, and some of the main reasons provided by these young women for going to the OB-GYN is to discuss, or obtain a prescription for, contraceptives. Through the expansion of pharmacists’ prescriptive authority, a likely consequence is that some women will relinquish going to the OB-GYN. However, the OB-GYN provides important services beyond contraceptives, such as preventive screenings for hypertension, cardiovascular diseases, alcohol abuse, mental health, etc., and there is evidence supporting both the effectiveness and cost–benefits of these interventions. By increasing access to contraceptives, the likely result is that many women will have less interaction with a physician and will receive fewer preventive screenings. I do not wish to suggest that these bills should not pass, nor that OB-GYNs should hold contraceptives hostage, only that there are consequences to expanded prescriptive authority that must be anticipated. Further, expanding prescriptive authority obscures the real problem: some individuals have trouble accessing the health care system, not merely trouble accessing hormonal contraceptives. The expansion of prescriptive authority to include contraceptives applies a Band-Aid to treat one aspect of this problem. What is needed is not merely expanded access to hormonal contraceptives, but better access to health care in general. (shrink)

The article brings together three short texts by Giorgio Agamben: “What is a people?” from Means without Ends from 1996, the third chapter from The Time that Remains from 2000 and the oral presentation “What is a movement?” from 2005. It analyzes Agamben’s idea of the people as internally divided. Through a juxtaposition with Marx’ notion of the proletariat, the article discusses Agamben’s attempt to develop a inoperative, but nonetheless revolutionary counter-paradigm to the biopolitical power paradigm of the West.

For relativistic particles with spin 1/2, which are described by the Dirac equation, a semiclassical trace formula is introduced that incorporates expectation values of observables in eigenstates of the Dirac-Hamiltonian. Furthermore, the semiclassical limit of an average of expectation values is expressed in terms of a classical average of the corresponding classical observable.