Behavioral interventions have shown promising neuroprotective effects, but the cascade of molecular, brain and behavioral changes involved in these benefits remains poorly understood. Projecte Moviment is a 12-week multi-domain, single-blind, proof-of-concept randomized controlled trial examining the cognitive effect and underlying mechanisms of an aerobic exercise, computerized cognitive training and a combined groups compared to a waitlist control group. Adherence was > 80% for 82/109 participants recruited. In this study we report intervention-related changes in plasma biomarkers and structural-MRI and how they (...) related to changes in physical activity and individual variables and their potential role as mediators in the cognitive changes. Our results show that although there were no significant changes in molecular biomarker concentrations in any intervention group, changes in ICAM-1 and SDF1-α were negatively associated with changes in physical activity outcomes in AE and COMB groups. Brain volume changes were found in the CCT showing a significant increase in precuneus volume. Sex moderated the brain volume change in the AE and COMB groups, suggesting that men may benefit more than women. Changes in molecular biomarkers and brain volumes did not significantly mediate the cognitive-related benefits found previously for any group. This study shows crucial initial molecular and brain volume changes related to lifestyle interventions at early stages and highlights the value of examining activity parameters, individual difference characteristics and using a multi-level analysis approach to address these questions. (shrink)

It is expected that children increasingly learn to identify errors throughout their schooling process and even before it. As a further step, however, some scholars have suggested how a culture of error should be implemented in the classroom for the student to be able not only to locate errors but also, and above all, to learn from them. Yet the various proposals aimed at generating a culture of error in the classroom keep regarding error as all those responses and reactions (...) that are not considered as true or correct in each specific case, thereby not realizing that many of these alleged errors are really anomalies with very different characteristics and consequences despite their seeming resemblance. In this paper, I rely on Ludwig Wittgenstein’s On Certainty to clarify the difference between errors and anomalies. Subsequently, I provide guidelines that may be adapted by each teacher to her students’ needs and development level in order to foster a culture of error that begins by distinguishing er... (shrink)

Wittgenstein’s conception of ‘persuasion’, understood as the persuader’s attempt to modify the persuadee’s certainties, has been recently misinterpreted by some scholars. For Persichetti has overlooked the fact that one cannot persuade unintentionally, while Marconi and Perissinotto have not only taken for granted that persuasion consists in the mere transfer of a world-picture or set of certainties to an individual even when she has not alternative or different certainties, but also that education is restricted to persuading or transmitting certainties. After clarifying (...) these misinterpretations, among others, I argue that persuasion is not used for teaching certainties at the outset, but for modifying them when they do not fit the ones expected by the persuader. If it is agreed that education partly consists in transmitting a world-picture, then persuasion constitutes a necessary resource for educators. Lastly, I provide a set of guidelines for teachers to draw attention to the basic aspects of persuasion that they should consider in the classroom. (shrink)

Literature on indoctrination has focused on imparting and revising beliefs, but it has hardly considered the way of teaching and acquiring certainties—in Wittgenstein’s sense. Therefore, the role played by rationality in the acquisition of our linguistic practices has been overestimated. Furthermore, analyses of the relationship between certainty and indoctrination contain major errors. In this paper, the clarification of the aforementioned issues leads me to suggest the avoidance of the term ‘indoctrination’ so as to avoid focusing on the suitability of the (...) case to the concept rather than on the analysis of the case itself. This should facilitate that the process of helping children to acquire a world-picture—by teaching them to ignore alternatives to certainties—is definitely accepted as normal and natural, for many beliefs are expected to end up becoming ungrounded certainties not only in the medium or long term, but also, and above all, in the short term. (shrink)

Among the elements which have gradually been complicating the countless representations of the Virgin Mary throughout history, this paper seeks to highlight and interpret conceptually one of special doctrinal significance in some Marian images during the fourteenth and fifteenth centuries: the temple, in whose interior some artists place some actual or symbolic episodes of Mary, from her birth or her Annunciation to the Sacra Conversazione, to give a few examples. Even though at first sight it looks as a mere scenographic (...) or ornamental ingredient, without iconographic value, this precise shape of temple reveals in fact some profound Mariological and Christological meanings. In that order of ideas, this essay is based on a double methodological strategy: first and foremost, to analyze some Marian images which include in the aforementioned period the shape of a temple, in order to see what kind of role such a religious building plays in them; secondly, to discover the relevant keys for interpreting such images, by analyzing some specific texts of the Church Fathers and medieval theologians who identify with Mary the figure of the «temple of God». For this reason, after a brief introduction to the problem, the present study is structured into three main parts inextricably intertwined: in the first we comparatively analyze twelve Marian paintings of the fourteenth and fifteenth centuries in which the Virgin appears inside a temple; in the second we explain the many exegesis that, in a consistent and strong patristic and theological tradition, identify the analogy of the templum Dei directly with the Virgin Mary, or indirectly with the Christ’s human body conceived in her womb; on the basis of this double analysis of images and exegetical writings, the third part of the paper states as a synthetic conclusion that the artistic representation of a temple or a church building in some Marian images of this period offers a compelling plastic metaphor of Mary and, ultimately, of her virginal divine motherhood. (shrink)

Philosophical Investigations, Volume 45, Issue 1, Page 91-97, January 2022.

Algunos autores han intentado considerar los delirios como certezas –entendidas en el sentido de Wittgenstein– debido a las similitudes que parecen existir entre sus respectivos estatus epistemológicos. Sin embargo, dicho intento ha sido criticado con agudeza, entre otras razones, porque el contenido de los delirios choca frontalmente con el contenido de las certezas, por lo que los delirios no pueden ser comprendidos debido a los cambios en las relaciones de significado. Pero es evidente que, aunque los delirios no se puedan (...) contemplar como certezas, muchos delirios afectan de un modo u otro al sistema de certezas del paciente. Partiendo de esta base, no es descabellado pensar que dicha influencia pudiera ser también recíproca: en otras palabras, parece sumamente recomendable analizar si algunos delirios se podrían contemplar como el resultado de variaciones en certezas. En este artículo llevo a cabo dicho análisis al intentar mostrar que el origen de algunos delirios pedestres y severos puede ser hallado en lo que llamaré “ceguera a posibilidades” e “incertidumbre”, términos que he desarrollado teniendo en cuenta la obra del filósofo Ludwig Wittgenstein. (shrink)

While in his late works Walter Benjamin seems to employ painting in an accessory way —either as an auratic counterfigure, or as a propitiatory victim of the technical image—, the allusions to the medium that guide his trajectory show its importance in the whole of his aesthetic reflection and even in the development of his theory of language. Especially relevant to understanding the general features of his idea of painting is the unpublished youth essay “On Painting, or Sign and Mark”, (...) as well as other writings of the same period that, although address the matter tangentially, shape it to a greater or lesser degree and determine its general scope. (shrink)

En el neoplatonismo tardío la profunda imbricación que hay entre filosofía y religión es una cuestión incontrovertible o, expresado con otras palabras, la estructura religiosa de la fi losofía neoplatónica plantea un horizonte especulativo muy singular que a todo lector moderno de esos textos, tanto en el género del comentario a los diálogos platónicos como en las obras más personales donde reluce la reflexión metafísico-teológica, no se le hace fácil comprender. En efecto, el modo singular de leer el diálogo platónico (...) Parménides, la manera de interpretar este texto fundacional del pensar neoplatónico, implica tener presente la influencia del vocabulario de los cultos antiguos de misterios y el modo en el cual dicho vocabulario se convierte en una parte orgánica o mejor dicho axial de tal estrategia exegética. En el presente trabajo se intentará mostrar tal estrategia exegética recurriendo a Proclo, el cual al discutir la irrelevancia de la interpretación lógica del Parménides se hace heredero de las claves de lectura aprendidas de su maestro, Siriano. (shrink)

El análisis detenido del pensamiento teológico-musical de Isidoro de Sevilla ha sido repetidamente ignorado por la crítica, hecho que ha provocado que el estado de la cuestión sobre la materia sea prácticamente inexistente. Debido a ello, este trabajo tiene un cuádruple objetivo. En primer lugar, fijar con precisión el citado estado de la cuestión. En segundo lugar, sistematizar el estudio del pensamiento teológico-musical isidoriano dentro de la totalidad de su pensamiento musical para que el primero pueda ser estudiado exhaustivamente y (...) de manera generalizada en el futuro. En tercer lugar, localizar, clasificar e introducir por primera vez todos los textos litúrgico-musicales de Isidoro de Sevilla de cara a su posterior estudio en futuras publicaciones. En cuarto lugar, exponer, también por primera vez, algunas de las ideas más relevantes del pensamiento teológico-musical isidoriano como ejemplo de la sistematización propuesta y como punto de partida para el establecimiento de futuras líneas de investigación. (shrink)

Wittgenstein scholars have tended to interpret the acquisition of certainties, and by extension, of a world-picture, as the achievement of a state in which these certainties are assimilated in a seemingly unconscious way as one masters language-games. However, it has not been stressed that the attainment of this state often involves facing a series of challenges or difficulties which must be overcome for the development of the world-picture and therefore the socialization process to be achieved. After showing, on the one (...) hand, how a world-picture is usually developed, and on the other hand, why a child who seemingly found itself trapped in a precocious skepticism might have serious problems in assimilating certainties, in this paper, I describe some of the challenges children often meet as they acquire a world-picture. Since the overcoming of these challenges is often needed for children to develop a world-picture, I aim at raising the awareness of the necessity of ‘learning to believe’, that is, of developing a series of skills that allow children to undertake the challenges described in this paper. (shrink)

Aunque Jusep Torres Campalans, la peculiar creación literaria de Max Aub, ha venido siendo objeto de numerosos comentarios, estudios y exposiciones, la peripecia editorial de la obra –un aspecto determinante para su adecuada valoración y recepción– apenas si ha captado el interés que merece hasta la fecha. Con el propósito de suplir esa carencia, el artículo se detiene en primera instancia en el marco intencional y coyuntural de su primera aparición y despliega después un ejercicio adaptado de bibliografía analítica donde (...) la edición príncipe es objeto de un somero análisis estructural y formal y se ve después sometida a contraste con todas y cada una de las ediciones en distintos idiomas que, desde 1958, se han venido sucediendo. Más allá de atender a las distintas versiones de una obra caracterizada en origen por una cuidada articulación de palabra, imagen y hechura material, el artículo aspira a promover la reflexión sobre el riesgo que entrañan ciertas rutinas editoriales para aquellas obras literarias que desbordan los márgenes de la convención. (shrink)

Aunque política y ciencia constituyen hoy en día ramas casi antagónicas del conocimiento humano -acaso combinables en ámbitos ficcionales como el cine y la literatura-, la relación entre filosofía política y astronomía es una constante histórica que alcanza especial fuerza en el pensamiento emancipatorio del siglo xix. El presente artículo sitúa en ese marco La eternidad por los astros y, asimismo, somete a contraste la peculiaridad retórica e ideológica de esta obra, en donde Louis-Auguste Blanqui propone una contigüidad entre orbe (...) celeste y sociedades humanas, basada en su análogo funcionamiento y su común atavismo. (shrink)

An analysis of the particular kind of determinism that is to be found in the moral election according to Leibniz shows the model of practical reason held in his philosophy. The hermeneutical clue used in the article is to make a parallelism between the model of rationality of God’s election to create the best possible world and that of human moral election.

Traducción, selección y estudio preliminar José María Felipe Mendoza * Edición bilingüe. Se recomienda descargar el PDF para visualizar mejor la traducción y el original en paralelo.

Este trabajo se centra en la indagación histórica del cosmopolitismo en el pensamiento decimonónico español de origen krausista como precursor en nuestro país de la idea de ciudadanía global y gobernanza cosmopolita. Hay que decir que el pensamiento krausista español de finales del siglo XIX, resulto crucial en el desarrollo de las ciencias sociales de nuestro país, interesándose por el derecho, la sociología, la psicología, la ciencia política y, sobre todo, la educación, al tiempo que también fue decisivo en la (...) emergencia del primer feminismo español. El objetico de este trabajo, por tanto, no ha sido otro que mostrar la importancia del hispanismo krausista en el desarrollo del cosmopolitismo, elucidando el alcance de su influencia en los más variados ámbitos de la vida de la época, lo que le confiere especificidad y una relevancia singular desde un punto de vista crítico e historiográfico. Los krausistas creían en una humanidad unificada, la educación integral y humanista, y la participación ciudadana. Abogaban por una sociedad equitativa y justa, la descentralización del poder, y la colaboración entre naciones. También promovían la tolerancia religiosa y el diálogo intercultural. (shrink)

Este artículo reseña: Oscar Celador Angón, Entidades locales y libertad religiosa, Ed. Dykinson, Madrid 2023, 214 pp.

Major depression etiopathogenesis is related to a wide variety of genetics, demographic and psychosocial factors, as well as to environmental factors. The objective of this study is to analyze sociodemographic and environmental variables that are related to the prevalence of depression through correlation analysis and to develop a regression model that explains the behavior of this disease from an ecological perspective. This is an ecological, retrospective, cross-sectional study. The target population was 1,148,430 individuals over the age of 16 who were (...) registered in Aragon (Spain) during 2010, with electronic medical records in the community’s primary health care centers. The spatial unit was the Basic Health Area (BHA). The dependent variable was the diagnosis of Depression and the ecological independent variables were: Demographic variables (gender and age), population distribution, typology of the entity, population structure by sex and age, by nationality, by education, by work, by salary, by marital status, structure of the household by number of members, and state of the buildings. The results show moderate and positive correlations appear with higher rates of depression in areas having a higher femininity index, higher population density, areas with a higher unemployment rate and higher average salary. The results of the linear regression show that aging +75 and rural entities act as protective factors for depression, while urban areas and deficient buildings act as risk factors. In conclusion, the ecological methodology may be a useful tool which, together with the statistical epidemiological analysis, can help in the political decision making process. (shrink)

Por providencia divina entendemos el cuidado y protección que ejerce Dios sobre los hombres. Esto no resulta claro para todos, desde los ateos hasta los deístas. La dificultad mayor está en la presencia y la experiencia del mal en el mundo y en la historia. Este artículo se acerca tanto a la filosofía como a la revelación bíblica para ofrecer una respuesta a la siempre difícil relación entre providencia y mal, teniendo como punto de llegada los principios hermenéuticos de la (...) creación. (shrink)

Fray Carlos Amigo Vallejo celebra este año su XXV aniversario como obispo de la Iglesia Católica (1973-1998). Su ministerio episcopal abarca dos etapas: Tánger (Marruecos) y la actual en Sevilla. El objetivo de este trabajo es dar a conocer la personalidad, el pensamiento y la actividad de este arzobispo a partir de sus 299 escritos pastorales durante estos 25 años.